Digoxin
453 interactions 2 explained in plain English 980 cited referencesDigoxin is a cardiac glycoside used to treat heart failure and abnormal heart rhythms by strengthening the heart's contractions and slowing heart rate. Read the full Digoxin drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Major
Digoxin Etodolac Lodine Increased digoxin exposure and prolonged half-life of digoxin Details Digoxin Etofenamate Increased digoxin exposure and prolonged half-life of digoxin Details Digoxin Etoricoxib Increased digoxin exposure and prolonged half-life of digoxin Details Digoxin Exenatide Bydureon Reduced digoxin exposure Details Digoxin Felbinac Increased digoxin exposure and prolonged half-life of digoxin Details Digoxin Felodipine Plendil® Increased digoxin exposure and an increased risk of bradycardia and advanced complete heart block Details Digoxin Fenoprofen Fenopron Increased digoxin exposure and prolonged half-life of digoxin Details Digoxin Fepradinol Increased digoxin exposure and prolonged half-life of digoxin Details Digoxin Feprazone Increased digoxin exposure and prolonged half-life of digoxin Details Digoxin Fingolimod Gilenya Severe bradycardia or heart block Details Digoxin Flibanserin Addyi Increased digoxin exposure and an increased risk of digoxin toxicity Details Digoxin Floctafenine Increased digoxin exposure and prolonged half-life of digoxin Details Digoxin Flufenamic Acid Increased digoxin exposure and prolonged half-life of digoxin Details Digoxin Fluoxetine RECONCILE Increased digoxin exposure and an increased risk of digoxin toxicity (nausea, vomiting, arrhythmias) Details Digoxin Flurbiprofen Ansaid Increased digoxin exposure and prolonged half-life of digoxin Details Digoxin Fluvoxamine Increased digoxin exposure Details Digoxin Fosinopril Monopril® An increased digoxin exposure Details Digoxin Fosphenytoin Cerebyx Reduced digoxin exposure Details Digoxin Fostamatinib Tavalisse Increased digoxin exposure Details Digoxin Gentamicin Increased digoxin exposure Details Digoxin Gepotidacin Blujepa Increased digoxin exposure Details Digoxin Gilteritinib Xospata Increased P-gp substrate exposure and increased incidence and severity of adverse reactions associated with the P-gp substrate Details Digoxin Ginkgo Increased digoxin exposure Details Digoxin Hawthorn Potentiation of digoxin effects Details Digoxin Hydrochlorothiazide Inzirqo Increased risk of digitalis toxicity (nausea, vomiting, arrhythmias) Details Digoxin Hydroflumethiazide Increased risk of digitalis toxicity (nausea, vomiting, arrhythmias) Details Digoxin Hydroxychloroquine Plaquenil Increased digoxin exposure Details Digoxin Ibrexafungerp Brexafemme Increased digoxin exposure Details Digoxin Ibrutinib Imbruvica Increased digoxin exposure Details Digoxin Imlunestrant Inluriyo Increased P-gp substrate exposure and an increased risk of P-gp substrate-related adverse reactions Details Digoxin Indapamide Increased risk of digitalis toxicity (nausea, vomiting, arrhythmias) Details Digoxin Indinavir Increased digoxin exposure Details Digoxin Indomethacin Indocin Increased digoxin exposure Details Digoxin Irbesartan Avapro An increased digoxin exposure Details Digoxin Isavuconazole Increased exposure of P-gp substrate Details Digoxin Isavuconazonium Cresemba Increased exposure of P-gp substrate Details Digoxin Isradipine DynaCirc® An increased risk of bradycardia and an increased risk of complete heart block Details Digoxin Istradefylline Nourianz Increased digoxin exposure Details Digoxin Itraconazole Sporanox Increased digoxin exposure and an increased risk of digoxin toxicity (nausea, vomiting, arrhythmias) Details Digoxin Ivabradine Corlanor An increased risk of bradycardia DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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