Metformin
378 interactions 1 explained in plain English 428 cited referencesMetformin is a biguanide medication used to help control blood sugar levels in type 2 diabetes. Read the full Metformin drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Major
Metformin Ranolazine Aspruzyo Increased metFORMIN exposure and an increased risk of lactic acidosis Details Metformin Somatrogon-Ghla Reduced insulin sensitivity Details Metformin Sparfloxacin Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Metformin Tafenoquine Arakoda Increased plasma concentrations of OCT2 and MATE substrates Details Metformin Thioctic Acid Increased risk of hypoglycemia Details Metformin Topiramate Eprontia An increased risk of lactic acidosis and reduced serum bicarbonate Details Metformin Trilaciclib Increased metFORMIN exposure and an increased risk of lactic acidosis Details Metformin Trimethoprim Primsol Increased metFORMIN exposure and an increased risk of lactic acidosis Details Metformin Trovafloxacin Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Metformin Tucatinib Tukysa Increased metFORMIN exposure and an increased risk of lactic acidosis Details Metformin Vandetanib Caprelsa Increased metFORMIN exposure and an increased risk of lactic acidosis Details Metformin Vimseltinib Romvimza Increased risk of OCT2 substrate exposure Details Metformin Zonisamide Zonegran An increased risk of lactic acidosis and reduced serum bicarbonate Details Metformin Moxifloxacin Injection Avelox Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Metformin Moxifloxacin Ophthalmic Moxeza® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Metformin Octreotide Bynfezia An increased risk of hypoglycemia and impaired glucose regulation Details Metformin Octreotide Injection Bynfezia An increased risk of hypoglycemia and impaired glucose regulation Details Metformin Ofloxacin Ophthalmic Ocuflox Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Metformin Ofloxacin Otic Floxin® Otic Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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