Methylene Blue
45 interactions 6 explained in plain English
Also sold as:
Provayblue
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Acetaminophen And Codeine
Methyldopa
Levodopa Oral Inhalation
Entacapone
Maprotiline
Deutetrabenazine
Moderate
Methylene Blue Acarbose Prandase® Explained An increased risk of hypoglycemia Details Methylene Blue Clonidine Transdermal Patch Catapres An increased risk of sedation and somnolence Details Methylene Blue Glimepiride Amaryl An increased risk of hypoglycemia Details Methylene Blue Glipizide Glucotrol An increased risk of hypoglycemia Details Methylene Blue Insulin Degludec (Rdna Origin) Injection Ryzodeg® (as a combination product containing Insulin Degludec and Insulin Aspart) An increased risk of hypoglycemia Details Methylene Blue Insulin Detemir (Rdna Origin) Injection Levemir An increased risk of hypoglycemia Details Methylene Blue Insulin Glulisine (Rdna Origin) Injection Apidra An increased risk of hypoglycemia Details Methylene Blue Metformin Fortamet® An increased risk of hypoglycemia Details Methylene Blue Nateglinide Starlix® An increased risk of hypoglycemia DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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