Metronidazole Vaginal

242 interactions 832 cited references

Also sold as: MetroGel® Vaginal Nuvessa Nuvessa® Vandazole Vandazole®

About Metronidazole Vaginal

Metronidazole is used to treat vaginal infections such as bacterial vaginosis (an infection caused from too much of certain bacteria in the vagina). Metronidazole is in a class of medications called nitroimidazole antimicrobials. It works by stopping the growth of bacteria. Read the full Metronidazole Vaginal drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Pimozide Piperaquine Saquinavir Sparfloxacin Terfenadine Thioridazine

15 Contraindicated 214 Major 13 Moderate

All (242) Contraindicated (15) Major (214) Moderate (13)

Major

Metronidazole Vaginal Lonafarnib Zokinvy An increased risk of QT interval prolongation and torsade de pointes Details Metronidazole Vaginal Loperamide Diamode An increased risk of QT interval prolongation, which may increase risk of cardiotoxicity (torsade de pointes, cardiac arrest) Details Metronidazole Vaginal Lumefantrine An increased risk of QT interval prolongation Details Metronidazole Vaginal Macimorelin Increased risk of QT interval prolongation Details Metronidazole Vaginal Mavorixafor Xolremdi An increased risk of QT interval prolongation and torsade de pointes Details Metronidazole Vaginal Mebendazole Emverm Increased risk of Stevens-Johnson syndrome and/or toxic epidermal necrolysis Details Metronidazole Vaginal Mefloquine Lariam® An increased risk of QT interval prolongation Details Metronidazole Vaginal Methadone Diskets An increased risk of QT interval prolongation Details Metronidazole Vaginal Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Metronidazole Vaginal Methotrimeprazine An increased risk of QT interval prolongation Details Metronidazole Vaginal Mifepristone Korlym An increased risk of QT interval prolongation Details Metronidazole Vaginal Milsaperidone An increased risk of QT interval prolongation Details Metronidazole Vaginal Mirtazapine Mirataz An increased risk of QT interval prolongation Details Metronidazole Vaginal Mizolastine An increased risk of QT interval prolongation Details Metronidazole Vaginal Mobocertinib Exkivity An increased risk of QT interval prolongation Details Metronidazole Vaginal Moricizine An increased risk of QT interval prolongation Details Metronidazole Vaginal Moxifloxacin Avelox An increased risk of QT interval prolongation Details Metronidazole Vaginal Mycophenolate Mofetil Decreased mycophenolate plasma exposure and possible reduced efficacy Details Metronidazole Vaginal Mycophenolic Acid Myfortic Decreased mycophenolate plasma exposure and possible reduced efficacy Details Metronidazole Vaginal Nelfinavir Viracept An increased risk of QT interval prolongation Details Metronidazole Vaginal Nilotinib An increased risk of QT interval prolongation Details Metronidazole Vaginal Norfloxacin An increased risk of QT interval prolongation Details Metronidazole Vaginal Octreotide Bynfezia An increased risk of QT interval prolongation Details Metronidazole Vaginal Ofloxacin Floxin® An increased risk of QT interval prolongation Details Metronidazole Vaginal Olanzapine An increased risk of QT interval prolongation Details Metronidazole Vaginal Olodaterol Striverdi An increased risk of QT interval prolongation and an increased risk of ventricular arrhythmias Details Metronidazole Vaginal Ondansetron An increased risk of QT interval prolongation Details Metronidazole Vaginal Osilodrostat Isturisa Increased risk of QT interval prolongation Details Metronidazole Vaginal Osimertinib Tagrisso Increased risk of QT interval prolongation Details Metronidazole Vaginal Oxaliplatin Increased risk of QT-interval prolongation Details Metronidazole Vaginal Ozanimod Additive effects on heart rate Details Metronidazole Vaginal Pacritinib Vonjo® An increased risk of QT interval prolongation Details Metronidazole Vaginal Paliperidone Erzofri An increased risk of QT interval prolongation Details Metronidazole Vaginal Panobinostat Farydak Increased risk of QT interval prolongation Details Metronidazole Vaginal Papaverine Pavacot® An increased risk of QT interval prolongation Details Metronidazole Vaginal Paroxetine Paxil An increased risk of QT interval prolongation Details Metronidazole Vaginal Pasireotide Signifor An increased risk of QT interval prolongation Details Metronidazole Vaginal Pazopanib Votrient An increased risk of QT-interval prolongation Details Metronidazole Vaginal Pentamidine NebuPent An increased risk of QT interval prolongation Details Metronidazole Vaginal Perphenazine An increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.