Metronidazole Vaginal

242 interactions 832 cited references

Also sold as: MetroGel® Vaginal Nuvessa Nuvessa® Vandazole Vandazole®

About Metronidazole Vaginal

Metronidazole is used to treat vaginal infections such as bacterial vaginosis (an infection caused from too much of certain bacteria in the vagina). Metronidazole is in a class of medications called nitroimidazole antimicrobials. It works by stopping the growth of bacteria. Read the full Metronidazole Vaginal drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Pimozide Piperaquine Saquinavir Sparfloxacin Terfenadine Thioridazine

15 Contraindicated 214 Major 13 Moderate

All (242) Contraindicated (15) Major (214) Moderate (13)

Major

Metronidazole Vaginal Phenobarbital Fidoquel An increased risk of QT interval prolongation, reduced metroNIDAZOLE exposure and reduced metroNIDAZOLE efficacy Details Metronidazole Vaginal Phenprocoumon An increased risk of bleeding Details Metronidazole Vaginal Phenytoin Dilantin An increased risk of phenytoin toxicity or reduced metroNIDAZOLE exposure Details Metronidazole Vaginal Pimavanserin Nuplazid An increased risk of QT interval prolongation Details Metronidazole Vaginal Pipamperone An increased risk of QT interval prolongation Details Metronidazole Vaginal Pitolisant Wakix Increased risk of QT interval prolongation Details Metronidazole Vaginal Ponesimod Ponvory An increased risk of QT interval prolongation Details Metronidazole Vaginal Posaconazole Noxafil An increased risk of QT interval prolongation Details Metronidazole Vaginal Primidone Mysoline An increased risk of QT interval prolongation, reduced metroNIDAZOLE exposure and reduced metroNIDAZOLE efficacy Details Metronidazole Vaginal Probucol An increased risk of QT interval prolongation Details Metronidazole Vaginal Procainamide Procan® An increased risk of QT interval prolongation Details Metronidazole Vaginal Prochlorperazine An increased risk of QT interval prolongation Details Metronidazole Vaginal Promethazine Phenadoz An increased risk of QT interval prolongation Details Metronidazole Vaginal Propafenone Rythmol An increased risk of QT interval prolongation Details Metronidazole Vaginal Protriptyline An increased risk of QT interval prolongation Details Metronidazole Vaginal Quetiapine Seroquel An increased risk of QT interval prolongation Details Metronidazole Vaginal Quinidine Cardioquin® An increased risk of QT interval prolongation Details Metronidazole Vaginal Quinine An increased risk of QT interval prolongation Details Metronidazole Vaginal Quizartinib Vanflyta An increased risk of QT interval prolongation Details Metronidazole Vaginal Ranolazine Aspruzyo An increased risk of QT interval prolongation Details Metronidazole Vaginal Relugolix Orgovyx Increased risk of QT interval prolongation Details Metronidazole Vaginal Revumenib Revuforj An increased risk of QT interval prolongation Details Metronidazole Vaginal Ribociclib Kisqali An increased risk of QT interval prolongation Details Metronidazole Vaginal Rilpivirine Edurant An increased risk of QT interval prolongation and torsade de pointes Details Metronidazole Vaginal Risperidone Perseris An increased risk of QT interval prolongation Details Metronidazole Vaginal Ritonavir Norvir An increased risk of QT interval prolongation Details Metronidazole Vaginal Selpercatinib Retevmo Increased risk of QT interval prolongation Details Metronidazole Vaginal Sertindole An increased risk of QT interval prolongation Details Metronidazole Vaginal Sertraline An increased risk of QT interval prolongation Details Metronidazole Vaginal Sevoflurane Petrem An increased risk of QT interval prolongation Details Metronidazole Vaginal Siponimod Mayzent An increased risk of QT interval prolongation Details Metronidazole Vaginal Sodium Phosphate OsmoPrep An increased risk of QT interval prolongation Details Metronidazole Vaginal Sodium Phosphate, Dibasic An increased risk of QT interval prolongation Details Metronidazole Vaginal Sodium Phosphate, Monobasic An increased risk of QT interval prolongation Details Metronidazole Vaginal Solifenacin Vesicare An increased risk of QT interval prolongation Details Metronidazole Vaginal Sorafenib Nexavar An increased risk of QT interval prolongation Details Metronidazole Vaginal Sotalol Betapace An increased risk of QT interval prolongation Details Metronidazole Vaginal Sulpiride An increased risk of QT interval prolongation Details Metronidazole Vaginal Sultopride An increased risk of QT interval prolongation Details Metronidazole Vaginal Sunitinib Sutent An increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.