Relugolix

340 interactions 260 explained in plain English 125 cited references

Also sold as: Orgovyx Orgovyx®

About Relugolix

Relugolix is a gonadotropin-releasing hormone receptor antagonist used to treat advanced prostate cancer in adult men. Read the full Relugolix drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 2, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

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22 Contraindicated 313 Major 5 Moderate

All (340) Contraindicated (22) Major (313) Moderate (5)

Major

Relugolix Triptorelin Explained Increased risk of QT interval prolongation Details Relugolix Tucatinib Tukysa Explained Increased relugolix exposure Details Relugolix Valbenazine Ingrezza Explained Increased relugolix exposure Details Relugolix Vandetanib Caprelsa Explained Increased relugolix exposure and an increased risk of QT interval prolongation Details Relugolix Vanzacaftor Explained Increased relugolix exposure Details Relugolix Vardenafil Levitra Explained Increased risk of QT interval prolongation Details Relugolix Velpatasvir Explained Increased relugolix exposure Details Relugolix Vemurafenib Zelboraf Explained Increased relugolix exposure and an increased risk of QT interval prolongation Details Relugolix Venetoclax Venclexta Explained Increased relugolix exposure Details Relugolix Venlafaxine Explained Increased risk of QT interval prolongation Details Relugolix Verapamil Calan Explained Increased relugolix exposure Details Relugolix Vibegron Gemtesa Explained Increased relugolix exposure Details Relugolix Vilanterol Explained Increased risk of QT interval prolongation Details Relugolix Vilazodone Viibryd Explained Increased relugolix exposure Details Relugolix Vimseltinib Romvimza Explained Increased risk of P-gp substrate exposure Details Relugolix Vinflunine Explained Increased risk of QT interval prolongation Details Relugolix Voclosporin Lupkynis Explained Increased relugolix exposure and an increased risk of QT interval prolongation Details Relugolix Vorapaxar Zontivity Explained Increased relugolix exposure Details Relugolix Voriconazole Vfend Explained Increased risk of QT interval prolongation, reduced voriconazole exposure and an reduced efficacy of voriconazole Details Relugolix Vorinostat Zolinza Explained Increased risk of QT interval prolongation Details Relugolix Voxilaprevir Explained Increased relugolix exposure Details Relugolix Zanubrutinib Brukinsa Explained Increased relugolix exposure Details Relugolix Zotepine Explained Increased risk of QT interval prolongation Details Relugolix Zuclopenthixol Explained Increased risk of QT interval prolongation Details Relugolix Amisulpride Injection Barhemsys Increased risk of QT interval prolongation Details Relugolix Aripiprazole Injection Abilify Increased risk of QT interval prolongation Details Relugolix Arsenic Trioxide Injection Trisenox Increased risk of QT interval prolongation Details Relugolix Asenapine Transdermal Patch Secuado Increased risk of QT interval prolongation Details Relugolix Cyclosporine Injection Atopica Increased relugolix exposure Details Relugolix Cyclosporine Ophthalmic Cequa Increased relugolix exposure Details Relugolix Degarelix Injection Firmagon Increased risk of QT interval prolongation Details Relugolix Dolasetron Injection Anzemet Increased risk of QT interval prolongation Details Relugolix Eribulin Injection Halaven Increased risk of QT interval prolongation Details Relugolix Famotidine Injection Calmicid Increased risk of QT interval prolongation Details Relugolix Foscarnet Injection Foscavir Increased risk of QT interval prolongation Details Relugolix Gatifloxacin Ophthalmic Zymar® Increased risk of QT interval prolongation Details Relugolix Goserelin Implant Zoladex Increased risk of QT interval prolongation Details Relugolix Granisetron Transdermal Patch Sancuso Increased risk of QT interval prolongation Details Relugolix Granisetron Injection Granisol Increased risk of QT interval prolongation Details Relugolix Histrelin Implant Supprelin Increased risk of QT interval prolongation Details

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