Rifampin

Major

Rifampin Clopidogrel Plavix Increased clopidogrel active metabolite exposure and an increased platelet inhibition Details Rifampin Cobimetinib Cotellic Decreased cobimetinib plasma concentrations Details Rifampin Cyclosporine Injection Atopica Increased or reduced cycloSPORINE exposure and potentially an increased risk of organ rejection Details Rifampin Cyclosporine Ophthalmic Cequa Increased or reduced cycloSPORINE exposure and potentially an increased risk of organ rejection Details Rifampin Dabigatran Pradaxa® Reduced dabigatran exposure, reduced efficacy of dabigatran and an increased risk of thrombosis Details Rifampin Dabigatran Etexilate Reduced dabigatran exposure, reduced efficacy of dabigatran and an increased risk of thrombosis Details Rifampin Daprodustat Jesduvroq Reduced daprodustat exposure and reduced efficacy of daprodustat Details Rifampin Dapsone Aczone Reduced dapsone exposure, reduced efficacy of dapsone, an increased hydroxylamine metabolite of dapsone and an increased the risk... Details Rifampin Dapsone Topical Aczone Reduced dapsone exposure, reduced efficacy of dapsone, an increased hydroxylamine metabolite of dapsone and an increased the risk... Details Rifampin Darolutamide Nubeqa Decreased darolutamide exposure Details Rifampin Dasatinib Phyrago Reduced dasatinib exposure and reduced efficacy of dasatinib Details Rifampin Deferasirox Exjade Decreased deferasirox concentrations Details Rifampin Deflazacort Emflaza Decreased exposure to active metabolite of deflazacort Details Rifampin Deuruxolitinib Reduced deuruxolitinib exposure and reduced efficacy of deuruxolitinib Details Rifampin Dexamethasone Injection Decadron Reduced dexAMETHasone exposure Details Rifampin Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Reduced dexAMETHasone exposure Details Rifampin Diazepam Nasal Spray Valtoco Reduced diazePAM exposure Details Rifampin Diazepam Rectal Diastat Reduced diazePAM exposure Details Rifampin Digoxin Cardoxin® Altered digoxin exposure and an increased risk of digoxin toxicity Details Rifampin Disopyramide Norpace Reduced disopyramide exposure Details Rifampin Docetaxel Beizray Reduced docetaxel exposure Details Rifampin Docetaxel Injection Beizray Reduced docetaxel exposure Details Rifampin Dolutegravir Juluca® (as a combination product containing dolutegravir, rilpivirine) Reduced dolutegravir exposure and reduced efficacy of dolutegravir Details Rifampin Doxorubicin Adriamycin Altered DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Rifampin Doxycycline Injection Acticlate Reduced doxycycline exposure and potential loss of doxycycline efficacy Details Rifampin Edoxaban Savaysa Decreased edoxaban concentration Details Rifampin Elacestrant Orserdu Reduced elacestrant exposure and reduced efficacy of elacestrant Details Rifampin Eluxadoline Viberzi Increased eluxadoline exposure Details Rifampin Enalapril Epaned Reduced enalapril active metabolite exposure Details Rifampin Encorafenib Braftovi Reduced encorafenib exposure and reduced efficacy of encorafenib Details Rifampin Entrectinib Rozlytrek Reduced entrectinib exposure and reduced efficacy of entrectinib Details Rifampin Eravacycline Injection Xerava Reduced eravacycline concentrations and efficacy Details Rifampin Erdafitinib Balversa Reduced erdafitinib exposure Details Rifampin Erlotinib Tarceva Decreased erlotinib exposure and potential loss of efficacy Details Rifampin Estradiol Delestrogen Reduced hormonal contraceptive exposure, reduced efficacy of hormonal contraceptives and increased risk of contraceptive failure Details Rifampin Estradiol Topical Divigel Reduced hormonal contraceptive exposure, reduced efficacy of hormonal contraceptives and increased risk of contraceptive failure Details Rifampin Estradiol Transdermal Patch Alora® Reduced hormonal contraceptive exposure, reduced efficacy of hormonal contraceptives and increased risk of contraceptive failure Details Rifampin Everolimus Afinitor Reduced everolimus exposure and reduced efficacy of everolimus Details Rifampin Exemestane Aromasin Reduced exemestane exposure Details Rifampin Fentanyl Transdermal Patch Duragesic® Reduced exposure of fentaNYL, reduced efficacy of fentaNYL and/or onset of opioid withdrawal symptoms Details