Drug & supplement interaction

1-androsterone + Olsalazine Sodium

Olsalazine Sodium brand name: Dipentum.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between 1-androsterone and Olsalazine Sodium in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

1-androsterone and Olsalazine Sodium

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Olsalazine Sodium and 1-androsterone in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

1-androsterone safety at a glance

1-androsterone overall Avoid It is a hormonal compound with real health risks and little safety testing.
Pregnancy Avoid Hormone-altering prohormones should never be used during pregnancy.
Breastfeeding Avoid Avoid while breastfeeding because of unknown hormonal risks to the baby.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Olsalazine Sodium and 1-androsterone? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Olsalazine Sodium

Interactions in our licensed database are recorded against drug classes, not just single drug names. Olsalazine Sodium is filed under a single classification — oral drugs. 1-androsterone has documented interactions with 1 drug class — the most serious being testosterone (moderate) — and none of Olsalazine Sodium’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

1-androsterone Does Interact With Other Medications

1-androsterone has 8 moderate known drug interactions in our database — Olsalazine Sodium isn’t one of them. If you take anything else, check it against the full list below.

Moderate 8 No known interaction 2,822 (incl. Olsalazine Sodium)
Taking anything else?

Check Another of Your Medications Against 1-androsterone

Covers the 2,830 medications we’ve checked against 1-androsterone. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests 1-androsterone and Olsalazine Sodium May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. 2 of them are worth acting on rather than waiting out — marked below.

  • Kidney problems Worth acting on Additional detail

    1-androsterone

    “Significant increases in serum creatinine of around 0.2 mg/dL and significant decreases in GFR of around 16.4 mL/min/1.72m2 have been reported in patients taking 1-androsterone for 4 weeks. Serum creatinine remained within normal range despite the elevation, GFR dropped below 89 mL/min/1.72m2, which is suggestive of renal impairment.”

    1-androsterone · Natural Medicines adverse-effect record, reported in myasthenia gravis.

    1 source cited
    1. 91095. Granados J, Gillum TL, Christmas KM, et al. Prohormone supplement 3b-hydroxy-5a-androst-1-en-17-one enhances resistance training gains but impairs user health. J Appl Physiol (1985). 2014;116(5):560-9.

    Olsalazine Sodium

    Listed in the ADVERSE REACTIONS section of the FDA label for Olsalazine Sodium. Read the label on DailyMed ›

  • Liver problems Worth acting on Additional detail

    1-androsterone

    “There is currently a limited amount of information on the adverse effects of 1-androsterone. A thorough evaluation of safety outcomes has not been conducted.

    Most Common Adverse Effects:

    Orally: Dyslipidemia, transaminitis, renal dysfunction.”

    1-androsterone · Natural Medicines adverse-effect record, reported in dyslipidemia.

    Olsalazine Sodium

    Listed in the ADVERSE REACTIONS section of the FDA label for Olsalazine Sodium. Read the label on DailyMed ›

Effects for Olsalazine Sodium come from the ADVERSE REACTIONS section of its FDA label; effects for 1-androsterone come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Everything else you take

See Every Supplement That Interacts With Olsalazine Sodium

This page covers 1-androsterone only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Olsalazine Sodium page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Olsalazine Sodium page

“Olsalazine sodium (Dipentum) treats ulcerative colitis, and it only works if enough of the drug travels intact to the colon, so anything that binds it or interferes with its passage through the gut deserves real attention. All 17 supplement interactions on file involve absorption, and one carries a major rating: activated charcoal, whi…”

Reviewed by 2 · Jul 18, 2026

Open the Olsalazine Sodium interaction page

One more smart check

Taking 1-androsterone as Part of a Dietary Supplement Product? Check It for Interactions

We hold 35 real supplement products containing 1-androsterone, each one broken down to its full ingredient list — and combination products often carry several ingredients besides 1-androsterone. Even though 1-androsterone itself has no known interaction with Olsalazine Sodium, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where 1-androsterone and Olsalazine Sodium Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement 1-androsterone
Top half

#452 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Olsalazine Sodium
Steady interest

#2,192 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every 1-androsterone reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The 1-androsterone and Olsalazine Sodium records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About 1-androsterone

What is 1-androsterone?

1-androsterone
  • Muscle building
  • Increasing strength
  • Athletic performance
  • Body recomposition

1-Androsterone (1-DHEA or 1-Andro) is a synthetic prohormone marketed to bodybuilders for muscle and strength gains, but it has not been proven safe or effective in quality human studies. It can affect hormones and may harm the liver and other organs, so most pharmacists would recommend avoiding it.

Synthetic compound (not a plant part) · Capsules, tablets, sometimes combined with other prohormones

An interaction check asks whether these two react with each other — it does not ask whether 1-androsterone is a good idea for someone in your situation. Here is what our 1-androsterone record says about it on its own.

1-androsterone: dosing

There is no established safe or standard dose for 1-androsterone, and no medical guideline supports its use. Products vary widely in strength and ingredients.Because of the health risks involved, the safest choice for most people is not to use it at all. Never combine it with other prohormones or hormone products.

From our 1-androsterone monograph — the full record covers uses, side effects and every documented interaction.

Read the full 1-androsterone monograph & all interactions
Medication

About Olsalazine

What Is Olsalazine Used For?

Brand name: Dipentum

Dipentum (olsalazine) is used to keep ulcerative colitis in remission — meaning it helps prevent the disease from flaring up after it has been brought under control. It is specifically approved for adults who are intolerant of sulfasalazine, another medication commonly used for ulcerative colitis.

Most-Reported Side Effects for Olsalazine Sodium

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Colitis ulcerative 19 reports
Diarrhea 14 reports
Fatigue 9 reports
Pain in extremity 7 reports
Pruritus 7 reports
See full Olsalazine drug information
Keep checking

Other Drugs & 1-androsterone

Browse every other medication we’ve checked against 1-androsterone — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
8Moderate
0Minor
2,821No known interaction
8 Moderate 2,821 No interaction
Moderate

8 interactions

No interaction 2,821 drugs checked — show the list

We also checked 1-androsterone against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,821 medications checked with no known interaction — see the full 1-androsterone list.

See the full 1-androsterone interactions page
See every supplement checked against Olsalazine Sodium, ranked by severity
Evidence & sources

1-androsterone References

The 2 references that drive our 1-androsterone monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Parr MK, Opfermann G, Geyer H, et al. Seized designer supplement named "1-Androsterone": identification as 3ß-hydroxy-5a-androst-1-en-17-one and its urinary elimination. Steroids 2011;76(6):540-7.
  2. Granados J, Gillum TL, Christmas KM, et al. Prohormone supplement 3b-hydroxy-5a-androst-1-en-17-one enhances resistance training gains but impairs user health. J Appl Physiol (1985). 2014;116(5):560-9.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking 1-androsterone and Olsalazine Sodium Together: Common Questions

Is it safe to take 1-androsterone with Olsalazine Sodium?
We do not list a known interaction between 1-androsterone and Olsalazine Sodium. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do 1-androsterone and Olsalazine Sodium have any of the same side effects?
Yes — our sources link each of them separately to 2 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the 1-androsterone and Olsalazine Sodium combination checked?
Interactions in our licensed database are recorded against drug classes. Olsalazine Sodium is filed under 1 classification, and 1-androsterone has documented interactions with 1 drug class — none of Olsalazine Sodium's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does 1-androsterone interact with any other medications?
Yes. 1-androsterone has 8 documented drug interactions in our database — Olsalazine Sodium is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Olsalazine Sodium interact with any supplements?
Yes. Olsalazine Sodium has documented interactions with 17 supplements in our database — 1-androsterone is not one of them. The Olsalazine Sodium interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

1-androsterone monograph Uses, safety profile, and every drug interaction in one place Olsalazine drug information The full plain-English guide to this medication Olsalazine Sodium supplement interactions Every supplement checked against Olsalazine Sodium, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Olsalazine Sodium and 1-androsterone?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.