Drug & supplement interaction

Acupressure + Propranolol

Propranolol brand names: Inderal LA, Inderal, Angilol, Syprol, Inderal Injection, and others.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Acupressure and Propranolol in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Acupressure and Propranolol

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Propranolol and Acupressure in our sources. This does not guarantee that the combination is completely free of risk — research on Acupressure alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Acupressure at all — not against Propranolol, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Acupressure is a treatment rather than something you take. Tell whoever provides it which medicines you use, and ask your prescriber whether it is appropriate for your health and treatment. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Acupressure safety at a glance

Acupressure overall Generally safe Generally safe and low-risk when applied gently by a trained person or with proper instruction.
Pregnancy Possibly Safe When used appropriately. Acupressure has been safely used during pregnancy in clinical trials without significant adverse effects. Read the full pregnancy detail
Breastfeeding Possibly Safe When used appropriately. Acupressure has been safely used during pregnancy in clinical trials without significant adverse effects. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Propranolol and Acupressure? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Acupressure Itself Has Been Linked To

This is not an interaction — nothing below involves Propranolol. It is the side-effect record for Acupressure on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Acupressure, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Bleeding or bruising Worth acting on Additional detail

    “Skin discomfort, such as bruising, itching, irritation, pressure, and inflammation at the site of application has been reported in people using both acupressure and sham acupressure.”

    Acupressure · Natural Medicines adverse-effect record, reported in pruritus.

    5 sources cited
    1. 103398. Zhang CS, Xia J, Zhang AL, Yang AW, Thien F, Li Y, Wu D, Cai J, DaCosta C, Xue CC. Ear acupressure for perennial allergic rhinitis: A multicenter randomized controlled trial. Am J Rhinol Allergy. 2014 Jul-Aug;28(4):e152-7. doi: 10.2500/ajra.2014.28.4081. PubMed
    2. 103407. Vallim ETA, Marques ADCB, Coelho RCFP, Guimarães PRB, Felix JVC, Kalinke LP. Auricular acupressure in the quality of life of women with breast cancer: a randomized clinical trial. Rev Esc Enferm USP. 2019 Dec 2;53:e03525. doi: 10.1590/S1980-220X2018043603
    3. 105120. Susana CT, Maria TML, Pilar DS, et al. Effectiveness of self-applied acupressure for cervical pain of benign origin (EDIDO-CUH): a randomized controlled clinical trial. Acupunct Med. 2020:964528420961398. PubMed
    4. 110311. Yeung WF, Yu BY, Chung KF, et al. Self-administered acupressure for insomnia disorder: A randomized controlled trial. Phytomedicine 2022;99:153993. PubMed
    5. 114084. Jiang ZF, Liu G, Sun XX, et al. Auricular acupressure for constipation in adults: a systematic review and meta-analysis. Front Physiol 2023;14:1257660. PubMed
  • Bloating or gas / Nausea Additional detail

    “Nausea, bloating, and stomachache have been reported rarely in clinical research.”

    Acupressure · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    2 sources cited
    1. 110307. Israel L, Rotter G, Förster-Ruhrmann U, et al. Acupressure in patients with seasonal allergic rhinitis: a randomized controlled exploratory trial. Chin Med 2021;16(1):137. PubMed
    2. 110311. Yeung WF, Yu BY, Chung KF, et al. Self-administered acupressure for insomnia disorder: A randomized controlled trial. Phytomedicine 2022;99:153993. PubMed
  • A fast or pounding heartbeat / Low blood pressure Additional detail

    “Hypotension and palpitations have been reported rarely in clinical trials.”

    Acupressure · Natural Medicines adverse-effect record, reported in hypotension.

    4 sources cited
    1. 105120. Susana CT, Maria TML, Pilar DS, et al. Effectiveness of self-applied acupressure for cervical pain of benign origin (EDIDO-CUH): a randomized controlled clinical trial. Acupunct Med. 2020:964528420961398. PubMed
    2. 110296. Chen SR, Hou WH, Lai JN, Kwong JSW, Lin PC. Effects of acupressure on anxiety: A systematic review and meta-analysis. J Integr Complement Med 2022;28(1):25-35. PubMed
    3. 110308. Lin J, Chen T, He J, Chung RC, Ma H, Tsang H. Impacts of acupressure treatment on depression: A systematic review and meta-analysis. World J Psychiatry 2022;12(1):169-186. PubMed
    4. 110313. Wu Y, Yang L, Zhong Z, et al. Auricular acupressure for hemodialysis patients with insomnia: A multicenter double-blind randomized sham-controlled trial. J Integr Complement Med 2022;28(4):339-348. PubMed
  • Itching Additional detail

    Recorded for Acupressure in the same Natural Medicines adverse-effect record shown under Bleeding or bruising above.

  • Dizziness / Headache Additional detail

    “Headache and dizziness have been reported in people using both acupressure and sham acupressure.”

    Acupressure · Natural Medicines adverse-effect record, reported in cluster headache.

    6 sources cited
    1. 103398. Zhang CS, Xia J, Zhang AL, Yang AW, Thien F, Li Y, Wu D, Cai J, DaCosta C, Xue CC. Ear acupressure for perennial allergic rhinitis: A multicenter randomized controlled trial. Am J Rhinol Allergy. 2014 Jul-Aug;28(4):e152-7. doi: 10.2500/ajra.2014.28.4081. PubMed
    2. 103407. Vallim ETA, Marques ADCB, Coelho RCFP, Guimarães PRB, Felix JVC, Kalinke LP. Auricular acupressure in the quality of life of women with breast cancer: a randomized clinical trial. Rev Esc Enferm USP. 2019 Dec 2;53:e03525. doi: 10.1590/S1980-220X2018043603
    3. 105120. Susana CT, Maria TML, Pilar DS, et al. Effectiveness of self-applied acupressure for cervical pain of benign origin (EDIDO-CUH): a randomized controlled clinical trial. Acupunct Med. 2020:964528420961398. PubMed
    4. 110296. Chen SR, Hou WH, Lai JN, Kwong JSW, Lin PC. Effects of acupressure on anxiety: A systematic review and meta-analysis. J Integr Complement Med 2022;28(1):25-35. PubMed
    5. 110308. Lin J, Chen T, He J, Chung RC, Ma H, Tsang H. Impacts of acupressure treatment on depression: A systematic review and meta-analysis. World J Psychiatry 2022;12(1):169-186. PubMed
    6. 110311. Yeung WF, Yu BY, Chung KF, et al. Self-administered acupressure for insomnia disorder: A randomized controlled trial. Phytomedicine 2022;99:153993. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Acupressure — expand a row for the licensed statement it rests on. We haven’t matched Propranolol to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Propranolol.

Special populations

Acupressure in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Safe

When used appropriately. Acupressure has been safely used during pregnancy in clinical trials without significant adverse effects.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Overlapping uses

What Propranolol Is Prescribed For, and What Acupressure Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Propranolol is a prescription medicine with approved uses on its FDA label. Acupressure is a treatment: what follows is what researchers have looked at it for, and how strong that evidence is.

Propranolol is prescribed for: This intravenous (IV) form of propranolol is used in hospital or clinical settings to treat dangerous heart rhythm problems. It is generally reserved for life-threatening arrhythmias (abnormal heart rhythms) or those that occur during anesthesia. Specific conditions it treats include fast heart rates coming from the upper chambers of the heart (supraventricular tachycardia), certain arrhythmias caused by digitalis toxicity, dangerous ventricular rhythms that haven't responded to other treatments, and fast heart rates caused by excess adrenaline-like substances during surgery.

Acupressure has been studied for:

  • Stroke studied, not established Acupressure has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Acupressure for stroke

    It is unclear if acupressure is beneficial for improving outcomes in patients who have experienced a stroke.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Propranolol on your own; if you are taking Acupressure for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Propranolol

This page covers Acupressure only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Propranolol page lists 236 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Indian Snakeroot (major) and Tyramine (major).

By severity: 5 major · 194 moderate · 37 minor.

From our pharmacist’s overview on the Propranolol page

“Propranolol (Inderal) slows the heart and lowers blood pressure, which is exactly why its 236-ingredient interaction list deserves genuine care. Five entries rate major, and those are the ones to understand first.”

Reviewed by 2 · Jul 18, 2026

Open the Propranolol interaction page

How much people look this up

Where Acupressure and Propranolol Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Acupressure
Steady interest

#1,084 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Propranolol
Top 10

#10 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Acupressure reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Acupressure and Propranolol records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Treatment approach

About Acupressure

What is Acupressure?

  • Nausea and vomiting
  • Tension and stress
  • Pain relief
  • Headache
  • Sleep problems
  • Menstrual cramps

Acupressure is a hands-on technique that applies physical pressure to specific points on the body, based on traditional Chinese medicine. It is not an herb or supplement. It is generally low-risk when done gently, and the best evidence is for easing certain types of nausea, though results for most other uses are mixed or limited.

Not applicable — acupressure is a physical technique, not a plant or supplement · Finger or hand pressure on body points; acupressure wristbands; acupressure mats

An interaction check asks whether these two react with each other — it does not ask whether Acupressure is a good idea for someone in your situation. Here is what our Acupressure record says about it on its own.

Acupressure: dosing

There is no standardized "dose" for acupressure because it is a physical technique, not a pill or supplement. Sessions and pressure vary from person to person. A practitioner may press on a point for a number of seconds to a few minutes, sometimes repeating several times.If you use a product such as an acupressure wristband or mat, follow the directions on the label.

From our Acupressure monograph — the full record covers uses, side effects and every documented interaction.

Read the full Acupressure monograph & all interactions
Medication

About Propranolol (Cardiovascular)

What Is Propranolol (Cardiovascular) Used For?

Brand names: Inderal LA, Inderal, Angilol, Syprol, Inderal Injection, Half-Inderal LA, Bedranol SR, Half Beta Prograne, Beta Prograne, Lopranol LA, Slo-Pro, InnoPran XL

This intravenous (IV) form of propranolol is used in hospital or clinical settings to treat dangerous heart rhythm problems. It is generally reserved for life-threatening arrhythmias (abnormal heart rhythms) or those that occur during anesthesia.

Specific conditions it treats include fast heart rates coming from the upper chambers of the heart (supraventricular tachycardia), certain arrhythmias caused by digitalis toxicity, dangerous ventricular rhythms that haven't responded to other treatments, and fast heart rates caused by excess adrenaline-like substances during surgery.

See full Propranolol (Cardiovascular) drug information
Keep checking

Other Drugs & Acupressure

Browse every other medication we’ve checked against Acupressure — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Acupressure References

The 20 references that drive our Acupressure monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Jamigorn M, Phupong V. Acupressure and vitamin B6 to relieve nausea and vomiting in pregnancy: a randomized study. Arch Gynecol Obstet 2007;276:245-9. PubMed
  2. Helmreich, R. J., Shiao, S. Y., and Dune, L. S. Meta-analysis of acustimulation effects on nausea and vomiting in pregnant women. Explore (NY) 2006;2(5):412-421. PubMed
  3. de Aloysio, D. and Penacchioni, P. Morning sickness control in early pregnancy by Neiguan point acupressure. Obstet Gynecol 1992;80(5):852-854.
  4. Alkaissi, A., Ledin, T., Odkvist, L. M., and Kalman, S. P6 acupressure increases tolerance to nauseogenic motion stimulation in women at high risk for PONV. Can J Anaesth 2005;52(7):703-709. PubMed
  5. Steele, N. M., French, J., Gatherer-Boyles, J., Newman, S., and Leclaire, S. Effect of acupressure by Sea-Bands on nausea and vomiting of pregnancy. J Obstet Gynecol Neonatal Nurs 2001;30(1):61-70. DOI
  6. Werntoft, E. and Dykes, A. K. Effect of acupressure on nausea and vomiting during pregnancy. A randomized, placebo-controlled, pilot study. J Reprod Med 2001;46(9):835-839.
  7. O'Brien, B., Relyea, M. J., and Taerum, T. Efficacy of P6 acupressure in the treatment of nausea and vomiting during pregnancy. Am J Obstet Gynecol 1996;174(2):708-715. PubMed
  8. Hyde, E. Acupressure therapy for morning sickness. A controlled clinical trial. J Nurse Midwifery 1989;34(4):171-178. PubMed
  9. Shin, H. S., Song, Y. A., and Seo, S. Effect of Nei-Guan point (P6) acupressure on ketonuria levels, nausea and vomiting in women with hyperemesis gravidarum. J Adv Nurs 2007;59(5):510-519. PubMed
  10. Zhang CS, Xia J, Zhang AL, Yang AW, Thien F, Li Y, Wu D, Cai J, DaCosta C, Xue CC. Ear acupressure for perennial allergic rhinitis: A multicenter randomized controlled trial. Am J Rhinol Allergy. 2014 Jul-Aug;28(4):e152-7. doi: 10.2500/ajra.2014.28.4081. PubMed
  11. Vallim ETA, Marques ADCB, Coelho RCFP, Guimarães PRB, Felix JVC, Kalinke LP. Auricular acupressure in the quality of life of women with breast cancer: a randomized clinical trial. Rev Esc Enferm USP. 2019 Dec 2;53:e03525. doi: 10.1590/S1980-220X2018043603
  12. Tara F, Bahrami-Taghanaki H, Amini Ghalandarabad M, Zand-Kargar Z, Azizi H, Esmaily H, Azizi H. The Effect of Acupressure on the Severity of Nausea, Vomiting, and Retching in Pregnant Women: A Randomized Controlled Trial. Complement Med Res. 2020;27(4):25 PubMed
  13. Susana CT, Maria TML, Pilar DS, et al. Effectiveness of self-applied acupressure for cervical pain of benign origin (EDIDO-CUH): a randomized controlled clinical trial. Acupunct Med. 2020:964528420961398. PubMed
  14. Hamidzadeh A, Tavakol Z, Maleki M, et al. Effect of acupressure at the BL67 spot on the spontaneous rotation of fetus with breech presentation: A randomized controlled trial. Explore (NY) 2021. PubMed
  15. Chen SR, Hou WH, Lai JN, Kwong JSW, Lin PC. Effects of acupressure on anxiety: A systematic review and meta-analysis. J Integr Complement Med 2022;28(1):25-35. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Having Acupressure While Taking Propranolol: Common Questions

Is it safe to have Acupressure while taking Propranolol?
We do not list a known interaction between Acupressure and Propranolol. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Acupressure and Propranolol used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Acupressure in each. That is a conversation for your prescriber, especially if Propranolol is being adjusted to a target.
Does Propranolol interact with any supplements?
Yes. Propranolol has documented interactions with 236 supplements in our database — Acupressure is not one of them. The Propranolol interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Propranolol and Acupressure?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.