Drug & supplement interaction

Arimistane + Abiraterone Acetate

Abiraterone Acetate brand names: Zytiga, Yonsa.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Arimistane and Abiraterone Acetate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Arimistane and Abiraterone Acetate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Abiraterone Acetate and Arimistane in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Arimistane safety at a glance

Arimistane overall Avoid It is a hormone-altering drug with little safety data, and regulators warn against aromatase inhibitor supplements.
Pregnancy Possibly Unsafe When used orally or parenterally. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing aromatase inhibit... Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally or parenterally. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing aromatase inhibit... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Abiraterone Acetate and Arimistane? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Abiraterone Acetate

Interactions in our licensed database are recorded against drug classes, not just single drug names. Abiraterone Acetate is filed under 5 classifications — including cytochrome p450 2d6 (cyp2d6) inhibitors, hepatotoxic drugs, cytochrome p450 3a4 (cyp3a4) substrates. Arimistane has documented interactions with 1 drug class — the most serious being aromatase inhibitors (moderate) — and none of Abiraterone Acetate’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Arimistane Does Interact With Other Medications

Arimistane has 4 moderate known drug interactions in our database — Abiraterone Acetate isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Arimistane

Covers the 2,830 medications we’ve checked against Arimistane. Pick one to open its full report.

Special populations

Arimistane in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally or parenterally. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing aromatase inhibitors are dangerous. Avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

From our Q&A

Questions About Arimistane or Abiraterone Acetate

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Arimistane or Abiraterone Acetate, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Abiraterone Acetate

This page covers Arimistane only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Abiraterone Acetate page lists 171 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Grapefruit (major), Siberian Cocklebur (major) and St. John's Wort (major).

By severity: 6 major · 128 moderate · 37 minor.

From our pharmacist’s overview on the Abiraterone Acetate page

“Six of the 171 supplement and herbal interactions on file for abiraterone acetate (Zytiga, Yonsa) are rated major, and with an advanced prostate cancer treatment there is little margin for a drug level that drifts, so these pairings deserve genuine care. The bulk of the list, 121 ingredients, affects the CYP3A4 enzyme that clears abira…”

Reviewed by 2 · Jul 18, 2026

Open the Abiraterone Acetate interaction page

One more smart check

Taking Arimistane as Part of a Dietary Supplement Product? Check It for Interactions

We hold 80 real supplement products containing Arimistane, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Arimistane. Even though Arimistane itself has no known interaction with Abiraterone Acetate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Arimistane and Abiraterone Acetate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Arimistane
Top half

#573 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Abiraterone Acetate
Top 10%

#227 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Arimistane reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Arimistane and Abiraterone Acetate records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Arimistane

What is Arimistane?

Arimistane
  • Lowering estrogen levels
  • Post-cycle therapy after steroid or prohormone use
  • Reducing gynecomastia ('gyno')
  • Boosting testosterone
  • Bodybuilding and physique support

Arimistane (sometimes sold as Estrovade) is a synthetic aromatase inhibitor marketed as a dietary supplement to lower estrogen and raise testosterone, often during or after steroid or prohormone cycles. It is not a true dietary ingredient, has very little human safety data, and U.S. regulators have warned against products containing aromatase inhibitors. Talk to a pharmacist or doctor before using it.

Not applicable (synthetic compound) · Capsules, tablets, powders

An interaction check asks whether these two react with each other — it does not ask whether Arimistane is a good idea for someone in your situation. Here is what our Arimistane record says about it on its own.

Arimistane: dosing

There is no officially established or proven safe dose for Arimistane. It has not gone through the testing that approved medicines undergo, so reliable dosing guidance does not exist.Product labels vary widely, and the actual amount in a given product may not match what is claimed. Honestly, for most people the safest choice is to avoid it.

From our Arimistane monograph — the full record covers uses, side effects and every documented interaction.

Read the full Arimistane monograph & all interactions
Medication

About Abiraterone

What Is Abiraterone Used For?

Brand names: Zytiga, Yonsa

Abiraterone acetate tablets are used to treat two types of advanced prostate cancer: metastatic castration-resistant prostate cancer (CRPC — cancer that has spread and keeps growing despite low testosterone levels) and metastatic high-risk castration-sensitive prostate cancer (CSPC — cancer that has spread but still responds to hormone-lowering treatment). It is always taken together with a corticosteroid — most products pair with prednisone, while Yonsa is specifically indicated with methylprednisolone.

All products — including Abiraterone, Abiraterone Acetate, Abirtega, Yonsa, and Zytiga — are taken by mouth as a tablet. Yonsa is approved only for metastatic CRPC, while the other products (Abiraterone, Abiraterone Acetate, Abirtega, and Zytiga) are approved for both metastatic CRPC and metastatic high-risk CSPC.

See full Abiraterone drug information
Keep checking

Other Drugs & Arimistane

Browse every other medication we’ve checked against Arimistane — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
4Moderate
0Minor
2,825No known interaction
Moderate

4 interactions

No interaction 2,825 drugs checked — show the list
Evidence & sources

Arimistane References

The 1 references that drive our Arimistane monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Arimistane and Abiraterone Acetate Together: Common Questions

Is it safe to take Arimistane with Abiraterone Acetate?
We do not list a known interaction between Arimistane and Abiraterone Acetate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Arimistane and Abiraterone Acetate combination checked?
Interactions in our licensed database are recorded against drug classes. Abiraterone Acetate is filed under 5 classifications, and Arimistane has documented interactions with 1 drug class — none of Abiraterone Acetate's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Arimistane interact with any other medications?
Yes. Arimistane has 4 documented drug interactions in our database — Abiraterone Acetate is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Abiraterone Acetate interact with any supplements?
Yes. Abiraterone Acetate has documented interactions with 171 supplements in our database — Arimistane is not one of them. The Abiraterone Acetate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Abiraterone Acetate and Arimistane?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.