Drug & supplement interaction

Asian Water Plantain + Pacritinib

Pacritinib brand name: Vonjo.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Asian Water Plantain and Pacritinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Asian Water Plantain and Pacritinib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Pacritinib and Asian Water Plantain in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Asian Water Plantain safety at a glance

Asian Water Planta... overall Use caution Human safety data are limited, and high or long-term use may stress the kidneys or liver.
Pregnancy Avoid Not enough safety information is available, so it is best avoided during pregnancy.
Breastfeeding Avoid There is no reliable safety data, so avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Pacritinib and Asian Water Plantain? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Pacritinib

Interactions in our licensed database are recorded against drug classes, not just single drug names. Pacritinib is filed under 5 classifications — including cytochrome p450 1a2 (cyp1a2) inhibitors, qt interval-prolonging drugs, cytochrome p450 3a4 (cyp3a4) inhibitors. Asian Water Plantain has documented interactions with 1 drug class — the most serious being nephrotoxic drugs (minor) — and none of Pacritinib’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Asian Water Plantain Does Interact With Other Medications

Asian Water Plantain has 355 minor known drug interactions in our database — Pacritinib isn’t one of them. If you take anything else, check it against the full list below.

Minor 355 No known interaction 2,475 (incl. Pacritinib)
Taking anything else?

Check Another of Your Medications Against Asian Water Plantain

Covers the 2,830 medications we’ve checked against Asian Water Plantain. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Asian Water Plantain and Pacritinib May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • Bleeding or bruising Worth acting on Additional detail

    Asian Water Plantain

    “One case report of drug-induced systemic toxicity, including hepatotoxicity, has occurred in a 59-year-old man with chronic hepatitis B who had taken six doses of a combination product containing Asian water plantain 3 weeks prior to admission. He presented with gum bleed and petechiae, and his admission lab values indicated fulminant liver failure.”

    Asian Water Plantain · Natural Medicines adverse-effect record, reported in hepatitis.

    1 source cited
    1. 99434. Yuen MF, Tam S, Fung J, Wong DK, Wong BC, Lai CL. Traditional Chinese medicine causing hepatotoxicity in patients with chronic hepatitis B infection: a 1-year prospective study. Aliment Pharmacol Ther. 2006 Oct 15;24(8):1179-86. PubMed

    Pacritinib

    Listed in the ADVERSE REACTIONS section of the FDA label for Pacritinib. Read the label on DailyMed ›

Reported for Asian Water Plantain but not commonly for Pacritinib: liver problems and kidney problems.

Effects for Pacritinib come from the ADVERSE REACTIONS section of its FDA label; effects for Asian Water Plantain come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Everything else you take

See Every Supplement That Interacts With Pacritinib

This page covers Asian Water Plantain only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Pacritinib page lists 158 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).

By severity: 8 major · 110 moderate · 40 minor.

From our pharmacist’s overview on the Pacritinib page

“Someone on pacritinib (Vonjo) is usually fighting myelofibrosis, and the supplements people reach for during cancer treatment, herbal blends, immune boosters, St. John's wort for mood, are where this list gets serious.”

Reviewed by 2 · Jul 18, 2026

Open the Pacritinib interaction page

How much people look this up

Where Asian Water Plantain and Pacritinib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Asian Water Plantain
Steady interest

#1,358 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Pacritinib
Steady interest

#1,462 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Asian Water Plantain reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Asian Water Plantain and Pacritinib records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Asian Water Plantain

What is Asian Water Plantain?

Asian Water Plantain
  • Promoting urination (diuretic)
  • Fluid retention and swelling
  • Urinary discomfort
  • Cholesterol and heart health support
  • Kidney and bladder support

Asian water plantain (Ze Xie) is a rhizome long used in traditional Chinese medicine, mainly as a diuretic and for fluid retention. Modern evidence is mostly limited to laboratory and animal studies, so its benefits in people are not well proven, and quality human safety data are lacking. Talk with a pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Alisma plantago-aquatica · Alismataceae · Dried rhizome (root-like stem), known as Rhizoma Alismatis or Ze Xie · Dried sliced rhizome, powders, decoctions (teas), capsules, and as part of multi-herb traditional Chinese medicine formulas

An interaction check asks whether these two react with each other — it does not ask whether Asian Water Plantain is a good idea for someone in your situation. Here is what our Asian Water Plantain record says about it on its own.

Asian Water Plantain: dosing

There is no well-established standardized dose for Asian water plantain as a supplement. In traditional Chinese medicine, the dried rhizome is typically used as part of a multi-herb formula prepared by a trained practitioner, not taken alone.If you use a commercial product, follow the directions on the label and do not exceed the recommended amount. Do not use it as a substitute for prescribed diuretics or other proven treatments.

From our Asian Water Plantain monograph — the full record covers uses, side effects and every documented interaction.

Read the full Asian Water Plantain monograph & all interactions
Medication

About Pacritinib

What Is Pacritinib Used For?

Brand name: Vonjo

Vonjo (pacritinib) is used to treat adults with intermediate or high-risk myelofibrosis (MF) — a serious bone marrow disease — including primary MF and secondary MF that developed after polycythemia vera or essential thrombocythemia (other blood disorders). It is specifically approved for patients whose platelet count is below 50 × 10⁹/L (very low platelets), a group that has limited treatment options.

This approval is based on demonstrated reductions in spleen size. Continued approval may depend on results from confirmatory trials showing broader clinical benefit.

See full Pacritinib drug information
Keep checking

Other Drugs & Asian Water Plantain

Browse every other medication we’ve checked against Asian Water Plantain — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
355Minor
2,474No known interaction
355 Minor 2,474 No interaction
Minor

355 interactions

Showing 60 of 355 minor interactions — see all 355 on the Asian Water Plantain page.

No interaction 2,474 drugs checked — show the list

We also checked Asian Water Plantain against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,474 medications checked with no known interaction — see the full Asian Water Plantain list.

See the full Asian Water Plantain interactions page
See every supplement checked against Pacritinib, ranked by severity
Evidence & sources

Asian Water Plantain References

The 1 references that drive our Asian Water Plantain monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Yuen MF, Tam S, Fung J, Wong DK, Wong BC, Lai CL. Traditional Chinese medicine causing hepatotoxicity in patients with chronic hepatitis B infection: a 1-year prospective study. Aliment Pharmacol Ther. 2006 Oct 15;24(8):1179-86. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Asian Water Plantain and Pacritinib Together: Common Questions

Is it safe to take Asian Water Plantain with Pacritinib?
We do not list a known interaction between Asian Water Plantain and Pacritinib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Asian Water Plantain and Pacritinib have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Asian Water Plantain and Pacritinib combination checked?
Interactions in our licensed database are recorded against drug classes. Pacritinib is filed under 5 classifications, and Asian Water Plantain has documented interactions with 1 drug class — none of Pacritinib's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Asian Water Plantain interact with any other medications?
Yes. Asian Water Plantain has 355 documented drug interactions in our database — Pacritinib is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Pacritinib interact with any supplements?
Yes. Pacritinib has documented interactions with 158 supplements in our database — Asian Water Plantain is not one of them. The Pacritinib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Asian Water Plantain monograph Uses, safety profile, and every drug interaction in one place Pacritinib drug information The full plain-English guide to this medication Pacritinib supplement interactions Every supplement checked against Pacritinib, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Pacritinib and Asian Water Plantain?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.