Banana + Lapatinib
Lapatinib brand name: Tykerb.
We found no known interaction between Banana and Lapatinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Banana and Lapatinib
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Lapatinib and Banana in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Banana safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Lapatinib
Interactions in our licensed database are recorded against drug classes, not just single drug names. Lapatinib is filed under 3 classifications — cytochrome p450 3a4 (cyp3a4) inhibitors, cytochrome p450 3a4 (cyp3a4) substrates, oral drugs. Banana has documented interactions with 1 drug class — the most serious being levodopa (moderate) — and none of Lapatinib’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Banana Does Interact With Other Medications
Banana has 5 moderate known drug interactions in our database — Lapatinib isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Banana
We haven’t checked that one against Banana yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Banana. Pick one to open its full report.
What Lapatinib Is Prescribed For, and What Banana Has Been Studied For
These two come up together because they touch the same health topic — not because they do the same job. Lapatinib is a prescription medicine with approved uses on its FDA label. Banana is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.
Lapatinib is prescribed for: Lapatinib tablets — sold under the brand name Tykerb — are used to treat advanced or metastatic breast cancer in patients whose tumors overexpress the HER2 protein. They are always used in combination with another medicine, not alone. Tykerb is approved in combination with capecitabine for HER2-positive advanced or metastatic breast cancer in patients who have already received prior treatment including an anthracycline, a taxane, and trastuzumab, and whose disease has progressed on trastuzumab. Tykerb is also approved in combination with letrozole for postmenopausal women with hormone receptor-positive, HER2-positive metastatic breast cancer when hormonal therapy is appropriate.
Banana has been studied for:
-
Cancer studied, not established Banana has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows
Banana for cancer
Although there has been interest in using topical banana green fruit for cancer, there is insufficient reliable information about the clinical effects of banana for this purpose.
Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Lapatinib on your own; if you are taking Banana for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.
See Every Supplement That Interacts With Lapatinib
This page covers Banana only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Lapatinib page lists 143 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).
By severity: 3 major · 100 moderate · 40 minor.
From our pharmacist’s overview on the Lapatinib page
“Of the 143 supplements on file for lapatinib (Tykerb), nearly all press on the same point, the CYP3A4 enzyme that clears this HER2-targeted breast cancer drug. That deserves real caution, since lapatinib only works when its blood level stays in range.”
Reviewed by 2 · Jul 18, 2026
Taking Banana as Part of a Dietary Supplement Product? Check It for Interactions
We hold 985 real supplement products containing Banana, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Banana. Even though Banana itself has no known interaction with Lapatinib, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Banana and Lapatinib Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#333 of 1,452 supplements looked up here in the last 7 days
#2,248 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Banana reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Banana and Lapatinib records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Banana
What is Banana?
- Source of potassium and energy
- Digestive health and diarrhea
- Blood pressure support
- Heartburn and stomach ulcers (traditional)
- Weight management
Bananas are a nutritious, widely eaten fruit that provide potassium, fiber, vitamin B6, and quick energy, and they are part of a healthy diet. While some traditional uses (like easing diarrhea or supporting blood pressure) have plausible support, most specific health claims are not strongly proven. For most people bananas are a safe food, but those with kidney problems or a latex-fruit allergy should be cautious.
Musa acuminata · Musaceae · Fruit (most common); peel, flower, and leaves are also used in some traditions · Fresh fruit, dried banana, banana powder, green (unripe) banana flour, smoothies
An interaction check asks whether these two react with each other — it does not ask whether Banana is a good idea for someone in your situation. Here is what our Banana record says about it on its own.
Banana: dosing
There is no official medicinal dose for bananas. As a food, one to a few bananas per day fits easily into a healthy diet for most people.For banana supplements, powders, or green banana flour, a standardized dose has not been established.
From our Banana monograph — the full record covers uses, side effects and every documented interaction.
About Lapatinib
What Is Lapatinib Used For?
Brand name: Tykerb
Lapatinib tablets — sold under the brand name Tykerb — are used to treat advanced or metastatic breast cancer in patients whose tumors overexpress the HER2 protein. They are always used in combination with another medicine, not alone.
Tykerb is approved in combination with capecitabine for HER2-positive advanced or metastatic breast cancer in patients who have already received prior treatment including an anthracycline, a taxane, and trastuzumab, and whose disease has progressed on trastuzumab. Tykerb is also approved in combination with letrozole for postmenopausal women with hormone receptor-positive, HER2-positive metastatic breast cancer when hormonal therapy is appropriate.
Most-Reported Side Effects for Lapatinib
From FAERS, the FDA’s public side-effect reporting system (15,427 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Banana
Browse every other medication we’ve checked against Banana — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
5 interactions
No interaction 2,824 drugs checked — show the list
We also checked Banana against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Losartan Potassium ›
- Testosterone ›
- Ivermectin ›
- Abemaciclib ›
- Aspirin ›
- Metoprolol ›
- Acetaminophen ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Tadalafil ›
- Docusate ›
- Tirzepatide ›
- Ibuprofen ›
- Methamphetamine ›
- Hydroxyurea ›
- Warfarin Sodium ›
- Valacyclovir ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Lisdexamfetamine ›
- Propranolol ›
- Metformin ›
- Amitriptyline ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Methotrexate ›
- Amlodipine Besylate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Fluoxetine ›
- Doxycycline ›
- Acyclovir ›
- Azithromycin ›
- Lamotrigine ›
- Pregabalin ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Quetiapine ›
- Clonazepam ›
- Levothyroxine, Liothyronine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Methylene Blue ›
- Duloxetine ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,824 medications checked with no known interaction — see the full Banana list.
Banana References
The 11 references that drive our Banana monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Ble-Castillo JL, Aparicio-Trápala MA, Francisco-Luria MU, Córdova-Uscanga R, Rodríguez-Hernández A, Méndez JD, Díaz-Zagoya JC. Effects of native banana starch supplementation on body weight and insulin sensitivity in obese type 2 diabetics. Int J Environ PubMed
- Jiménez-Domínguez G, Ble-Castillo JL, Aparicio-Trápala MA, Juárez-Rojop IE, Tovilla-Zárate CA, Ble-Castillo DJ, García-Vázquez C, Olvera-Hernández V, Pérez-Pimienta B, Diaz-Zagoya JC, Mendez JD. Effects of Acute Ingestion of Native Banana Starch on Glycem
- Nieman DC, Gillitt ND, Sha W, et al. Metabolomics-Based Analysis of Banana and Pear Ingestion on Exercise Performance and Recovery. J Proteome Res 2015;14(12):5367-77. doi: 10.1021/acs.jproteome.5b00909. PubMed
- Rabbani GH, Ahmed S, Hossain I, Islam R, Marni F, Akhtar M, Majid N. Green banana reduces clinical severity of childhood shigellosis: a double-blind, randomized, controlled clinical trial. Pediatr Infect Dis J. 2009 May;28(5):420-5. PubMed
- Schoeffl V, Varatorn R, Blinnikov O, Vidamaly V. Intestinal obstruction due to phytobezoars of banana seeds: a case report. Asian J Surg. 2004 Oct;27(4):348-51. PubMed
- Don M, Longo G. Food protein-induced enterocolitis syndrome due to banana: an uncommon entity. Eur Ann Allergy Clin Immunol. 2013 Apr;45(2):61-2.
- Tazoe M, Narita M, Sakuta R, Nagai T, Narita N. Hyperkalemia and hyperdopaminemia induced by an obsessive eating of banana in an anorexia nervosa adolescent. Brain Dev. 2007 Jul;29(6):369-72. PubMed
- Meynadier J, Meynadier JM, Guilhou JJ. [Contact urticaria in atopic patients. Apropos of 2 cases]. Ann Dermatol Venereol. 1982;109(10):871-4.
- Hauswirth DW, Burks AW. Banana anaphylaxis with a negative commercial skin test. J Allergy Clin Immunol. 2005 Mar;115(3):632-3. PubMed
- Hotozuka S, Yasu T, Hikita E, Shirota M. Interaction Between Levodopa and Banana in a Patient With Parkinson's Disease. Am J Ther 2022;29(4):465-467. PubMed
- Arias-Córdova Y, Ble-Castillo JL, García-Vázquez C, et al. Resistant Starch Consumption Effects on Glycemic Control and Glycemic Variability in Patients with Type 2 Diabetes: A Randomized Crossover Study. Nutrients 2021;13(11):4052. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Banana and Lapatinib Together: Common Questions
Is it safe to take Banana with Lapatinib?
Do Banana and Lapatinib have any of the same side effects?
Are Banana and Lapatinib used for the same thing?
How was the Banana and Lapatinib combination checked?
Does Banana interact with any other medications?
Does Lapatinib interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Keep Exploring
Still Have a Question About Lapatinib and Banana?
Our pharmacists answer your medication & supplement questions — free.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.