Drug & supplement interaction

Banana + Tasimelteon

Tasimelteon brand names: Hetlioz, Hetlioz Lq.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Banana and Tasimelteon in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Tasimelteon states a food rule worth keeping to.

Know someone taking this? Share
Interaction report

Banana and Tasimelteon

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Tasimelteon and Banana in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Banana safety at a glance

Banana overall Generally safe Bananas are a common, generally safe food for most people when eaten in normal amounts.
Pregnancy Generally safe Bananas as a food are considered safe in pregnancy; concentrated supplements are less studied.
Breastfeeding Generally safe Bananas as a food are considered safe while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Tasimelteon and Banana? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Tasimelteon

Interactions in our licensed database are recorded against drug classes, not just single drug names. Tasimelteon is filed under 5 classifications — including cytochrome p450 1a2 (cyp1a2) substrates, cytochrome p450 1a2 (cyp1a2) substrates, cns depressants. Banana has documented interactions with 1 drug class — the most serious being levodopa (moderate) — and none of Tasimelteon’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Banana Does Interact With Other Medications

Banana has 5 moderate known drug interactions in our database — Tasimelteon isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Banana

Covers the 2,830 medications we’ve checked against Banana. Pick one to open its full report.

What to actually watch for

What Banana Itself Has Been Linked To

This is not an interaction — nothing below involves Tasimelteon. It is the side-effect record for Banana on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Banana, this list is the first place to look. 4 entries are worth acting on rather than waiting out — marked below.

  • A bowel blockage Worth acting on Additional detail

    “Orally, banana starch isolated from green bananas has resulted in bloating, gas, cramping, and softer feces. When consumed prior to exercise, fullness and bloating during exercise have been reported. In children, nausea, vomiting, and abdominal distension have been reported when banana is used in the treatment of diarrhea.”

    Banana · Natural Medicines adverse-effect record, reported in diarrhea.

    6 sources cited
    1. 93448. Ble-Castillo JL, Aparicio-Trápala MA, Francisco-Luria MU, Córdova-Uscanga R, Rodríguez-Hernández A, Méndez JD, Díaz-Zagoya JC. Effects of native banana starch supplementation on body weight and insulin sensitivity in obese type 2 diabetics. Int J Environ PubMed
    2. 93449. Jiménez-Domínguez G, Ble-Castillo JL, Aparicio-Trápala MA, Juárez-Rojop IE, Tovilla-Zárate CA, Ble-Castillo DJ, García-Vázquez C, Olvera-Hernández V, Pérez-Pimienta B, Diaz-Zagoya JC, Mendez JD. Effects of Acute Ingestion of Native Banana Starch on Glycem
    3. 110619. Arias-Córdova Y, Ble-Castillo JL, García-Vázquez C, et al. Resistant Starch Consumption Effects on Glycemic Control and Glycemic Variability in Patients with Type 2 Diabetes: A Randomized Crossover Study. Nutrients 2021;13(11):4052. PubMed
    4. 93459. Nieman DC, Gillitt ND, Sha W, et al. Metabolomics-Based Analysis of Banana and Pear Ingestion on Exercise Performance and Recovery. J Proteome Res 2015;14(12):5367-77. doi: 10.1021/acs.jproteome.5b00909. PubMed
    5. 93461. Rabbani GH, Ahmed S, Hossain I, Islam R, Marni F, Akhtar M, Majid N. Green banana reduces clinical severity of childhood shigellosis: a double-blind, randomized, controlled clinical trial. Pediatr Infect Dis J. 2009 May;28(5):420-5. PubMed
    6. 93777. Schoeffl V, Varatorn R, Blinnikov O, Vidamaly V. Intestinal obstruction due to phytobezoars of banana seeds: a case report. Asian J Surg. 2004 Oct;27(4):348-51. PubMed
  • High potassium Worth acting on Additional detail

    “In one case report, an adolescent girl who consumed nothing other than 20 bananas daily developed hyperkalemia and hyperdopaminemia. These changes in the blood resulted in pseudoaldosteronism and dysthymia.”

    Banana · Natural Medicines adverse-effect record, reported in hyperkalemia.

    1 source cited
    1. 93780. Tazoe M, Narita M, Sakuta R, Nagai T, Narita N. Hyperkalemia and hyperdopaminemia induced by an obsessive eating of banana in an anorexia nervosa adolescent. Brain Dev. 2007 Jul;29(6):369-72. PubMed
  • Shortness of breath / An allergic reaction Worth acting on Additional detail

    “Orally, banana has been reported to cause allergic reaction, including urticaria and redness, abdominal pain and nausea, dyspnea, and anaphylaxis. Topically, contact urticara has also been reported. Skin testing is not always accurate, even for patients with severe banana allergy.”

    Banana · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).

    2 sources cited
    1. 93784. Meynadier J, Meynadier JM, Guilhou JJ. [Contact urticaria in atopic patients. Apropos of 2 cases]. Ann Dermatol Venereol. 1982;109(10):871-4.
    2. 93793. Hauswirth DW, Burks AW. Banana anaphylaxis with a negative commercial skin test. J Allergy Clin Immunol. 2005 Mar;115(3):632-3. PubMed
  • A severe allergic reaction / Hives Worth acting on Additional detail

    Recorded for Banana in the same Natural Medicines adverse-effect record shown under A bowel blockage above.

  • Bloating or gas Additional detail

    Recorded for Banana in the same Natural Medicines adverse-effect record shown under A bowel blockage above.

  • Stomach pain Additional detail

    Recorded for Banana in the same Natural Medicines adverse-effect record shown under Shortness of breath / An allergic reaction above.

  • Diarrhea / Vomiting Additional detail

    Recorded for Banana in the same Natural Medicines adverse-effect record shown under A bowel blockage above.

Showing the 10 most notable of 11 recorded effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

Everything above comes from the Natural Medicines adverse-effect record for Banana — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Tasimelteon’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Tasimelteon column appears here.

How to take them

Some Tasimelteon Products Have a Food Rule — Banana Should Not Break It

At least one FDA label for a product containing Tasimelteon says to take it on an empty stomach. Most supplements — Banana included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Tasimelteon on its own and move Banana to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Tasimelteon products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

2 DOSAGE AND ADMINISTRATION Indicated Population Dosage Form Body Weight Recommended Dosage Non-24 ( 2.2 ) Adults Capsules Not applicable 20 mg one hour prior to bedtime Nighttime sleep disturbances in SMS ( 2.3 ) Patients 16 years of age and older Capsules Not applicable 20 mg one hour prior to bedtime Pediatric Patients 3 to 15 years of age Oral Suspension ≤ 28 kg 0.7 mg/kg one hour before bedti

From the Dosage and Administration section of the FDA label we read for Tasimelteon — where that label names a specific product, the instruction is that product's. See the Tasimelteon drug page ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Tasimelteon

This page covers Banana only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tasimelteon page lists 218 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Grapefruit (major).

By severity: 9 major · 166 moderate · 43 minor.

From our pharmacist’s overview on the Tasimelteon page

“Tasimelteon (Hetlioz) resets the body clock in people with non-24-hour sleep-wake disorder, and the sleep aids they often reach for, melatonin and kava among them, sit on an interaction list that deserves real respect. Nine of the 218 ingredients on file rate major, mostly in two directions: sedatives like kava stack drowsiness onto a…”

Reviewed by 2 · Jul 18, 2026

Open the Tasimelteon interaction page

One more smart check

Taking Banana as Part of a Dietary Supplement Product? Check It for Interactions

We hold 985 real supplement products containing Banana, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Banana. Even though Banana itself has no known interaction with Tasimelteon, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Banana and Tasimelteon Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Banana
Top 25%

#330 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Tasimelteon
Steady interest

#1,943 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Banana reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Banana and Tasimelteon records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Banana

What is Banana?

Banana
  • Source of potassium and energy
  • Digestive health and diarrhea
  • Blood pressure support
  • Heartburn and stomach ulcers (traditional)
  • Weight management

Bananas are a nutritious, widely eaten fruit that provide potassium, fiber, vitamin B6, and quick energy, and they are part of a healthy diet. While some traditional uses (like easing diarrhea or supporting blood pressure) have plausible support, most specific health claims are not strongly proven. For most people bananas are a safe food, but those with kidney problems or a latex-fruit allergy should be cautious.

Musa acuminata · Musaceae · Fruit (most common); peel, flower, and leaves are also used in some traditions · Fresh fruit, dried banana, banana powder, green (unripe) banana flour, smoothies

An interaction check asks whether these two react with each other — it does not ask whether Banana is a good idea for someone in your situation. Here is what our Banana record says about it on its own.

Banana: dosing

There is no official medicinal dose for bananas. As a food, one to a few bananas per day fits easily into a healthy diet for most people.For banana supplements, powders, or green banana flour, a standardized dose has not been established.

From our Banana monograph — the full record covers uses, side effects and every documented interaction.

Read the full Banana monograph & all interactions
Medication

About Tasimelteon

What Is Tasimelteon Used For?

Brand names: Hetlioz, Hetlioz Lq

Tasimelteon capsules are approved to treat Non-24-Hour Sleep-Wake Disorder (Non-24) in adults. Non-24 is a condition where the body's internal clock does not align with the normal 24-hour day, causing sleep and wake times to shift continuously.

Hetlioz capsules are also approved to treat nighttime sleep disturbances in Smith-Magenis Syndrome (SMS) in patients 16 years of age and older. Hetlioz LQ oral suspension is approved specifically for nighttime sleep disturbances in SMS in pediatric patients ages 3 to 15 years.

Most-Reported Side Effects for Tasimelteon

From FAERS, the FDA’s public side-effect reporting system (5,770 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Insomnia 728 reports
Middle insomnia 414 reports
Somnolence 408 reports
Headache 386 reports
Nightmare 268 reports
See full Tasimelteon drug information
Keep checking

Other Drugs & Banana

Browse every other medication we’ve checked against Banana — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
5Moderate
0Minor
2,824No known interaction
Moderate

5 interactions

No interaction 2,824 drugs checked — show the list
Evidence & sources

Banana References

The 11 references that drive our Banana monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Ble-Castillo JL, Aparicio-Trápala MA, Francisco-Luria MU, Córdova-Uscanga R, Rodríguez-Hernández A, Méndez JD, Díaz-Zagoya JC. Effects of native banana starch supplementation on body weight and insulin sensitivity in obese type 2 diabetics. Int J Environ PubMed
  2. Jiménez-Domínguez G, Ble-Castillo JL, Aparicio-Trápala MA, Juárez-Rojop IE, Tovilla-Zárate CA, Ble-Castillo DJ, García-Vázquez C, Olvera-Hernández V, Pérez-Pimienta B, Diaz-Zagoya JC, Mendez JD. Effects of Acute Ingestion of Native Banana Starch on Glycem
  3. Nieman DC, Gillitt ND, Sha W, et al. Metabolomics-Based Analysis of Banana and Pear Ingestion on Exercise Performance and Recovery. J Proteome Res 2015;14(12):5367-77. doi: 10.1021/acs.jproteome.5b00909. PubMed
  4. Rabbani GH, Ahmed S, Hossain I, Islam R, Marni F, Akhtar M, Majid N. Green banana reduces clinical severity of childhood shigellosis: a double-blind, randomized, controlled clinical trial. Pediatr Infect Dis J. 2009 May;28(5):420-5. PubMed
  5. Schoeffl V, Varatorn R, Blinnikov O, Vidamaly V. Intestinal obstruction due to phytobezoars of banana seeds: a case report. Asian J Surg. 2004 Oct;27(4):348-51. PubMed
  6. Don M, Longo G. Food protein-induced enterocolitis syndrome due to banana: an uncommon entity. Eur Ann Allergy Clin Immunol. 2013 Apr;45(2):61-2.
  7. Tazoe M, Narita M, Sakuta R, Nagai T, Narita N. Hyperkalemia and hyperdopaminemia induced by an obsessive eating of banana in an anorexia nervosa adolescent. Brain Dev. 2007 Jul;29(6):369-72. PubMed
  8. Meynadier J, Meynadier JM, Guilhou JJ. [Contact urticaria in atopic patients. Apropos of 2 cases]. Ann Dermatol Venereol. 1982;109(10):871-4.
  9. Hauswirth DW, Burks AW. Banana anaphylaxis with a negative commercial skin test. J Allergy Clin Immunol. 2005 Mar;115(3):632-3. PubMed
  10. Hotozuka S, Yasu T, Hikita E, Shirota M. Interaction Between Levodopa and Banana in a Patient With Parkinson's Disease. Am J Ther 2022;29(4):465-467. PubMed
  11. Arias-Córdova Y, Ble-Castillo JL, García-Vázquez C, et al. Resistant Starch Consumption Effects on Glycemic Control and Glycemic Variability in Patients with Type 2 Diabetes: A Randomized Crossover Study. Nutrients 2021;13(11):4052. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Banana and Tasimelteon Together: Common Questions

Is it safe to take Banana with Tasimelteon?
We do not list a known interaction between Banana and Tasimelteon. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Banana and Tasimelteon at the same time of day?
At least one FDA label for a product containing Tasimelteon says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Tasimelteon on its own and move Banana to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
How was the Banana and Tasimelteon combination checked?
Interactions in our licensed database are recorded against drug classes. Tasimelteon is filed under 5 classifications, and Banana has documented interactions with 1 drug class — none of Tasimelteon's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Banana interact with any other medications?
Yes. Banana has 5 documented drug interactions in our database — Tasimelteon is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Tasimelteon interact with any supplements?
Yes. Tasimelteon has documented interactions with 218 supplements in our database — Banana is not one of them. The Tasimelteon interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Tasimelteon and Banana?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.