Drug & supplement interaction

Banderol + Orlistat

Orlistat brand names: Xenical, Alli.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Banderol and Orlistat in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Banderol and Orlistat

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Orlistat and Banderol in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Banderol safety at a glance

Banderol overall Use caution Human safety data are very limited, so use carefully and under professional guidance.
Pregnancy Avoid Not enough safety information; avoid during pregnancy.
Breastfeeding Avoid Not enough safety information; avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Pharmacist analysis

Due to the lack of scientific data, it is difficult to make definitive statements about potential drug interactions involving Banderol (Otoba parvifolia).

Although some preliminary studies done in a lab setting have noted some potential interactions (which can be found in our interaction checker), more are needed to better understand the safety of Banderol when combined with OTC (over-the-counter) or prescription drugs.

Still wondering about combining Orlistat and Banderol? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Orlistat

Interactions in our licensed database are recorded against drug classes, not just single drug names. Orlistat is filed under 2 classifications — including oral drugs. Banderol has documented interactions with 2 drug classes — the most serious being organic anion transporter 1 (oat1) substrates (moderate) and organic anion transporter 3 (oat3) substrates (moderate) — and none of Orlistat’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Banderol Does Interact With Other Medications

Banderol has 177 moderate known drug interactions in our database — Orlistat isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Banderol

Covers the 2,830 medications we’ve checked against Banderol. Pick one to open its full report.

What to actually watch for

What Orlistat’s Own FDA Label Lists

This is not an interaction — none of it involves Banderol. These are the most notable effects listed in the ADVERSE REACTIONS section of Orlistat’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Bleeding in the gut Worth acting on
  • Low blood sugar Worth acting on
  • Pancreatitis Worth acting on
  • Wheezing Worth acting on
  • Low mood Worth acting on
  • A severe allergic reaction Worth acting on
  • Hives Worth acting on
  • Liver problems Worth acting on
  • Bleeding or bruising Worth acting on
  • A higher chance of infection Worth acting on

Showing the 10 most notable of 28 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Orlistat. Read the label on DailyMed › Where a percentage is shown, it is the share of 25,755 voluntary FDA FAERS reports for Orlistat that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Banderol’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Banderol side to compare — that is a limit of the record, not a statement that Banderol has no side effects.

Everything else you take

See Every Supplement That Interacts With Orlistat

This page covers Banderol only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Orlistat page lists 18 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Fish Oil (moderate) and Glucomannan (moderate).

By severity: 1 major · 8 moderate · 9 minor.

From our pharmacist’s overview on the Orlistat page

“People who take Orlistat (Xenical, Alli) for weight loss often browse the very supplement aisle where fiber products and fish oil sit, and both show up on this page, so it deserves genuine attention before you mix anything in. Nearly all 18 ingredients on file can change how oral medications absorb from the gut, and the single major-ra…”

Reviewed by 2 · Jul 18, 2026

Open the Orlistat interaction page

How much people look this up

Where Banderol and Orlistat Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Banderol
Top half

#579 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Orlistat
Top half

#896 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Banderol is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Banderol reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Banderol and Orlistat records this page draws on were last updated June 20, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Banderol

What is Banderol?

Banderol
  • Lyme disease support
  • Antimicrobial
  • Antifungal
  • Immune support
  • Inflammation

Banderol is a Nutramedix-branded herbal extract made from the bark of the Amazonian tree Otoba parvifolia, most often promoted as part of alternative Lyme disease protocols. There is very little high-quality human research to support its use, so the evidence behind its benefits is weak and largely preliminary. Talk with your pharmacist or doctor before using it, and never use it to replace proven treatments.

Otoba parvifolia · Myristicaceae · Bark (extract) · Liquid tincture/drops, capsules

An interaction check asks whether these two react with each other — it does not ask whether Banderol is a good idea for someone in your situation. Here is what our Banderol record says about it on its own.

Banderol: dosing

There is no official, standardized dose for Banderol. It has not been studied enough in humans to set a proven safe and effective amount.If you choose to use it, follow the directions on the product label exactly, since the manufacturer's tincture is typically dosed as a small number of drops in water.

From our Banderol monograph — the full record covers uses, side effects and every documented interaction.

Read the full Banderol monograph & all interactions
Medication

About Orlistat

What Is Orlistat Used For?

Brand names: Xenical, Alli

Xenical and prescription-strength orlistat are approved to help obese adults lose weight and keep it off when used with a reduced-calorie diet. They are intended for people with a body mass index (BMI) of 30 or higher, or 27 or higher if other risk factors such as high blood pressure, diabetes, or dyslipidemia (abnormal cholesterol or fat levels in the blood) are present.

Alli is the over-the-counter version, approved for weight loss in overweight adults 18 and older when used with a reduced-calorie, low-fat diet and exercise program.

Most-Reported Side Effects for Orlistat

From FAERS, the FDA’s public side-effect reporting system (25,755 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Rectal discharge 2,434 reports
Gastrointestinal disorder 2,186 reports
Constipation 1,991 reports
Diarrhea 1,960 reports
Weight increased 1,944 reports
See full Orlistat drug information
Keep checking

Other Drugs & Banderol

Browse every other medication we’ve checked against Banderol — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
177Moderate
0Minor
2,652No known interaction
Moderate

177 interactions

Showing 60 of 177 moderate interactions — see all 177 on the Banderol page.

No interaction 2,652 drugs checked — show the list
Evidence & sources

Banderol References

The 3 sources that drive our Banderol monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Banderol is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Lyme Disease and Alternative Treatments — NIH NCCIH Source
  2. Using Dietary Supplements Wisely — NIH NCCIH Source
  3. Herbal Supplements — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Banderol and Orlistat Together: Common Questions

Is it safe to take Banderol with Orlistat?
We do not list a known interaction between Banderol and Orlistat. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Banderol and Orlistat combination checked?
Interactions in our licensed database are recorded against drug classes. Orlistat is filed under 2 classifications, and Banderol has documented interactions with 2 drug classes — none of Orlistat's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Banderol interact with any other medications?
Yes. Banderol has 177 documented drug interactions in our database — Orlistat is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Orlistat interact with any supplements?
Yes. Orlistat has documented interactions with 18 supplements in our database — Banderol is not one of them. The Orlistat interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Orlistat and Banderol?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.