Bee Pollen + Alosetron
Alosetron brand name: Lotronex.
We found no known interaction between Bee Pollen and Alosetron in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Bee Pollen and Alosetron
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Alosetron and Bee Pollen in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Bee Pollen safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Alosetron
Interactions in our licensed database are recorded against drug classes, not just single drug names. Alosetron is filed under 3 classifications — serotonergic drugs, serotonergic drugs, oral drugs. Bee Pollen has documented interactions with 1 drug class — the most serious being warfarin (coumadin) (moderate) — and none of Alosetron’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Bee Pollen Does Interact With Other Medications
Bee Pollen has 2 moderate known drug interactions in our database — Alosetron isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Bee Pollen
We haven’t checked that one against Bee Pollen yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Bee Pollen. Pick one to open its full report.
Bee Pollen in Pregnancy & Breastfeeding
When used orally. There is some concern that bee pollen might have uterine stimulant effects; avoid using.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
What Alosetron Is Prescribed For, and What Bee Pollen Has Been Studied For
These two come up together because they touch the same health topic — not because they do the same job. Alosetron is a prescription medicine with approved uses on its FDA label. Bee Pollen is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.
Alosetron is prescribed for: Alosetron tablets — available as Alosetron, Alosetron Hydrochloride, and Lotronex — are approved only for women with severe diarrhea-predominant irritable bowel syndrome (IBS) whose symptoms have lasted 6 months or longer and who have not gotten adequate relief from conventional therapy. Other causes of GI symptoms must be ruled out first. To qualify as severe, diarrhea-predominant IBS must include diarrhea plus at least one of the following: frequent and severe abdominal pain or discomfort, frequent bowel urgency or fecal incontinence (accidental stool leakage), or significant disruption to daily activities. Clinical studies have not confirmed the same benefit in men.
Bee Pollen has been studied for:
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Diarrhea studied, not established Bee Pollen has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows
Bee Pollen for diarrhea
Although there has been interest in using oral bee pollen for diarrhea, there is insufficient reliable information about the clinical effects of bee pollen for this purpose.
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Constipation studied, not established Bee Pollen has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows
Bee Pollen for constipation
Although there has been interest in using oral bee pollen for constipation, there is insufficient reliable information about the clinical effects of bee pollen for this purpose.
Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Alosetron on your own; if you are taking Bee Pollen for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.
Questions About Bee Pollen or Alosetron
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Bee Pollen or Alosetron, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Alosetron
This page covers Bee Pollen only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Alosetron page lists 38 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Lithium (major), 5-htp (moderate), Acetyl-l-carnitine (moderate) and Ayahuasca (moderate).
By severity: 2 major · 25 moderate · 11 minor.
From our pharmacist’s overview on the Alosetron page
“Alosetron (Lotronex) treats severe diarrhea-predominant IBS by acting on serotonin receptors in the gut, and that is where most of its 38 supplement interactions come from. Twenty of the ingredients, 5-HTP among them, raise serotonin on their own, and stacking them on a serotonin-acting drug is a combination I want you to treat with re…”
Reviewed by 2 · Jul 18, 2026
Taking Bee Pollen as Part of a Dietary Supplement Product? Check It for Interactions
We hold 686 real supplement products containing Bee Pollen, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Bee Pollen. Even though Bee Pollen itself has no known interaction with Alosetron, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Bee Pollen and Alosetron Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#279 of 1,452 supplements looked up here in the last 7 days
#1,755 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Bee Pollen reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Bee Pollen and Alosetron records this page draws on were last updated July 11, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Bee Pollen
What is Bee Pollen?
- General energy and vitality
- Immune support
- Nutritional supplement
- Athletic performance
- Allergy relief (traditional belief)
- Skin and wound care
Bee pollen is a nutrient-rich product collected by bees and marketed as a 'superfood' for energy and immune support, but solid human evidence for most of these claims is lacking. It can cause serious allergic reactions in some people, and it should be avoided during pregnancy and breastfeeding because safety is not established.
Pollen collected by honeybees (often combined with nectar and bee secretions) · Granules, capsules, tablets, powder, chewables
An interaction check asks whether these two react with each other — it does not ask whether Bee Pollen is a good idea for someone in your situation. Here is what our Bee Pollen record says about it on its own.
Bee Pollen: dosing
There is no official or standardized dose for bee pollen. Products vary widely in their content and strength, so the right amount is not well defined.If you choose to use it, follow the directions on the product label and start with a small amount to see how your body reacts.
From our Bee Pollen monograph — the full record covers uses, side effects and every documented interaction.
About Alosetron
What Is Alosetron Used For?
Brand name: Lotronex
Alosetron tablets — available as Alosetron, Alosetron Hydrochloride, and Lotronex — are approved only for women with severe diarrhea-predominant irritable bowel syndrome (IBS) whose symptoms have lasted 6 months or longer and who have not gotten adequate relief from conventional therapy. Other causes of GI symptoms must be ruled out first.
To qualify as severe, diarrhea-predominant IBS must include diarrhea plus at least one of the following: frequent and severe abdominal pain or discomfort, frequent bowel urgency or fecal incontinence (accidental stool leakage), or significant disruption to daily activities. Clinical studies have not confirmed the same benefit in men.
Other Drugs & Bee Pollen
Browse every other medication we’ve checked against Bee Pollen — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
2 interactions
No interaction 2,827 drugs checked — show the list
We also checked Bee Pollen against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Sertraline ›
- Losartan Potassium ›
- Testosterone ›
- Ivermectin ›
- Abemaciclib ›
- Aspirin ›
- Metoprolol ›
- Acetaminophen ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Tadalafil ›
- Docusate ›
- Tirzepatide ›
- Ibuprofen ›
- Methamphetamine ›
- Hydroxyurea ›
- Valacyclovir ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Lisdexamfetamine ›
- Propranolol ›
- Metformin ›
- Amitriptyline ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Methotrexate ›
- Amlodipine Besylate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Fluoxetine ›
- Doxycycline ›
- Acyclovir ›
- Azithromycin ›
- Lamotrigine ›
- Pregabalin ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Quetiapine ›
- Clonazepam ›
- Levothyroxine, Liothyronine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Methylene Blue ›
- Duloxetine ›
- Buspirone ›
- Citalopram ›
- Ciprofloxacin ›
- Bisoprolol ›
Showing the 60 most looked-up of 2,827 medications checked with no known interaction — see the full Bee Pollen list.
Bee Pollen References
The 15 references that drive our Bee Pollen monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Shad JA, Chinn CG, Brann OS. Acute hepatitis after ingestion of herbs. South Med J 1999;92:1095-7. PubMed
- Puente S, Iniguez A, Subirats M, et al. [Eosinophilic gastroenteritis caused by bee pollen sensitization]. Med Clin (Barc) 1997;108:698-700.
- Winther K, Hedman C. Assessment of the Effects of the Herbal Remedy Femal on the Symptoms of Premenstrual Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study. Curr Ther Res Clin Exp 2002;63:344-53. DOI
- Cohen SH, Yunginger JW, Rosenberg N, Fink JN. Acute allergic reaction after composite pollen ingestion. J Allergy Clin Immunol 1979;64:270-4. PubMed
- Hurren KM, Lewis CL. Probable interaction between warfarin and bee pollen. Am J Health Syst Pharm 2010;67:2034-7. PubMed
- Akiyasu T, Paudyal B, Paudyal P, et al. A case report of acute renal failure associated with bee pollen contained in nutritional supplements. Ther Apher Dial 2010;14:93-7. PubMed
- Greenberger, P. A. and Flais, M. J. Bee pollen-induced anaphylactic reaction in an unknowingly sensitized subject. Ann.Allergy Asthma Immunol 2001;86(2):239-242. PubMed
- Lin FL, Vaughan TR, Vandewalker ML, et al. Hypereosinophilia, neurologic, and gastrointestinal symptoms after bee-pollen ingestion. J Allergy Clin Immunol 1989;83(4):793-796. PubMed
- Mansfield LE, Goldstein GB. Anaphylactic reaction after ingestion of local bee pollen. Ann Allergy 1981;47(3):154-156.
- Choi JH, Jang YS, Oh JW, Kim CH, Hyun IG. Bee pollen-induced anaphylaxis: a case report and literature review. Allergy Asthma Immunol Res 2015 Sep;7(5):513-7. PubMed
- Nonotte-Varly C. Allergenicity of Artemisia contained in bee pollen is proportional to its mass. Eur Ann Allergy Clin Immunol 2015;47(6):218-24.
- Leang ZX, Thalayasingam M, O'Sullivan M. A paediatric case of exercise-augmented anaphylaxis following bee pollen ingestion in Western Australia. Asia Pac Allergy. 2022 Jul 12;12(3):e23. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Bee Pollen and Alosetron Together: Common Questions
Is it safe to take Bee Pollen with Alosetron?
Do Bee Pollen and Alosetron have any of the same side effects?
Are Bee Pollen and Alosetron used for the same thing?
How was the Bee Pollen and Alosetron combination checked?
Does Bee Pollen interact with any other medications?
Does Alosetron interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.