Drug & supplement interaction

Beta-cryptoxanthin + Naloxegol

Naloxegol brand name: Movantik.

No Known Interaction
Medically reviewed by · Updated October 2026 · Pair last verified Oct 4, 2026
The bottom line No known interaction

We found no known interaction between Beta-cryptoxanthin and Naloxegol in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Naloxegol states a food rule worth keeping to.

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Interaction report

Beta-cryptoxanthin and Naloxegol

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Naloxegol and Beta-cryptoxanthin in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Beta-cryptoxanthin at all — not against Naloxegol, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Beta-cryptoxanthin safety at a glance

Beta-cryptoxanthin overall Use caution Considered safe in normal food amounts, but the safety of high-dose supplements is not well studied.
Pregnancy Likely Safe When used orally and appropriately in amounts found in foods. There is insufficient reliable information available about the safety of supplemental beta-cryptox... Read the full pregnancy detail
Breastfeeding Likely Safe When used orally and appropriately in amounts found in foods. There is insufficient reliable information available about the safety of supplemental beta-cryptox... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Naloxegol and Beta-cryptoxanthin? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Beta-cryptoxanthin Itself Has Been Linked To

This is not an interaction — nothing below involves Naloxegol. It is the side-effect record for Beta-cryptoxanthin on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Beta-cryptoxanthin, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Yellowing of the skin or eyes Worth acting on Additional detail

    “Orally, beta-cryptoxanthin may cause carotenemia. While this yellowing of the skin is benign, carotenemia can be mistaken for jaundice.”

    Beta-cryptoxanthin · Natural Medicines adverse-effect record, reported in neonatal jaundice.

Everything above comes from the Natural Medicines adverse-effect record for Beta-cryptoxanthin — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Naloxegol’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Naloxegol column appears here.

Special populations

Beta-cryptoxanthin in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Safe

When used orally and appropriately in amounts found in foods. There is insufficient reliable information available about the safety of supplemental beta-cryptoxanthin; avoid use.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

How to take them

Some Naloxegol Products Have a Food Rule — Beta-cryptoxanthin Should Not Break It

At least one FDA label for a product containing Naloxegol says to take it on an empty stomach. Most supplements — Beta-cryptoxanthin included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Naloxegol on its own and move Beta-cryptoxanthin to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Naloxegol products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

(2.1) Take on an empty stomach at least 1 hour prior to the first meal of the day or 2 hours after the meal.

From the Dosage and Administration section of the FDA label we read for Naloxegol — where that label names a specific product, the instruction is that product's. See the Naloxegol drug page ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Overlapping uses

What Naloxegol Is Prescribed For, and What Beta-cryptoxanthin Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Naloxegol is a prescription medicine with approved uses on its FDA label. Beta-cryptoxanthin is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Naloxegol is prescribed for: Naloxegol treats opioid-induced constipation (OIC). That is constipation caused by taking opioid pain medicine. Movantik is used in adults with chronic non-cancer pain. This includes people with chronic pain from prior cancer or its treatment who do not need frequent (for example, weekly) opioid dose increases.

Beta-cryptoxanthin has been studied for:

  • Cancer studied, not established Beta-cryptoxanthin has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Beta-cryptoxanthin for cancer

    It is unclear if dietary beta-cryptoxanthin intake can reduce the risk of cancer.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Naloxegol on your own; if you are taking Beta-cryptoxanthin for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Naloxegol

This page covers Beta-cryptoxanthin only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Naloxegol page lists 138 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 94 moderate · 41 minor.

From our pharmacist’s overview on the Naloxegol page

“Naloxegol (Movantik) relieves the constipation that opioids cause, and this is a list that deserves real care before you add anything from it. Nearly all of the trouble traces to a single enzyme, CYP3A4, which the body relies on to clear naloxegol.”

Reviewed by 2 · Jul 18, 2026

Open the Naloxegol interaction page

How much people look this up

Where Beta-cryptoxanthin and Naloxegol Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Beta-cryptoxanthin
Steady interest

#786 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Naloxegol
Steady interest

#1,694 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Beta-cryptoxanthin is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Beta-cryptoxanthin reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Beta-cryptoxanthin and Naloxegol records this page draws on were last updated October 6, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Beta-cryptoxanthin

What is Beta-cryptoxanthin?

  • Antioxidant support
  • Eye health
  • Bone health
  • Vitamin A source
  • General wellness

Beta-cryptoxanthin is a natural orange-red plant pigment (a carotenoid) found in fruits like oranges, tangerines, and papaya, and it can be turned into vitamin A in the body. Diets rich in beta-cryptoxanthin are linked in some studies to better bone and lung health, but the evidence for supplements is limited. For most people, getting it from colorful fruits and vegetables is the safest and best-studied approach.

Naturally found in fruits and vegetables; also made as a supplement · Capsules, softgels, and multivitamin/carotenoid blends; naturally present in whole foods

An interaction check asks whether these two react with each other — it does not ask whether Beta-cryptoxanthin is a good idea for someone in your situation. Here is what our Beta-cryptoxanthin record says about it on its own.

Beta-cryptoxanthin: dosing

There is no established standard supplement dose for beta-cryptoxanthin. Most research reflects amounts obtained through a normal diet rich in fruits and vegetables rather than from pills.If you choose to take a supplement, follow the directions on the product label and do not exceed the recommended amount.

From our Beta-cryptoxanthin monograph — the full record covers uses, side effects and every documented interaction.

Read the full Beta-cryptoxanthin monograph & all interactions
Medication

About Naloxegol

What Is Naloxegol Used For?

Brand name: Movantik

Naloxegol treats opioid-induced constipation (OIC). That is constipation caused by taking opioid pain medicine.

Movantik is used in adults with chronic non-cancer pain. This includes people with chronic pain from prior cancer or its treatment who do not need frequent (for example, weekly) opioid dose increases.

See full Naloxegol drug information
Keep checking

Other Drugs & Beta-cryptoxanthin

Browse every other medication we’ve checked against Beta-cryptoxanthin — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Beta-cryptoxanthin against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Beta-cryptoxanthin list.

See the full Beta-cryptoxanthin interactions page
See every supplement checked against Naloxegol, ranked by severity
Evidence & sources

Beta-cryptoxanthin References

The 2 sources that drive our Beta-cryptoxanthin monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Beta-cryptoxanthin is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Vitamin A and Carotenoids - Health Professional Fact Sheet — NIH Office of Dietary Supplements Source
  2. Vitamin A — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Beta-cryptoxanthin and Naloxegol Together: Common Questions

Is it safe to take Beta-cryptoxanthin with Naloxegol?
We do not list a known interaction between Beta-cryptoxanthin and Naloxegol. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Beta-cryptoxanthin and Naloxegol at the same time of day?
At least one FDA label for a product containing Naloxegol says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Naloxegol on its own and move Beta-cryptoxanthin to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
Are Beta-cryptoxanthin and Naloxegol used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Beta-cryptoxanthin in each. That is a conversation for your prescriber, especially if Naloxegol is being adjusted to a target.
Does Naloxegol interact with any supplements?
Yes. Naloxegol has documented interactions with 138 supplements in our database — Beta-cryptoxanthin is not one of them. The Naloxegol interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Beta-cryptoxanthin monograph Uses, safety profile, and every drug interaction in one place Naloxegol drug information The full plain-English guide to this medication Naloxegol supplement interactions Every supplement checked against Naloxegol, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Naloxegol and Beta-cryptoxanthin?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.