Drug & supplement interaction

Black Mustard + Mitomycin

Mitomycin brand names: Mutamycin, Mitosol, Jelmyto.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Black Mustard and Mitomycin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Black Mustard and Mitomycin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Mitomycin and Black Mustard in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Black Mustard safety at a glance

Black Mustard overall Use caution Generally safe as a food spice, but concentrated seeds or oil can irritate the skin and digestive tract.
Pregnancy Likely Unsafe When used orally for medicinal purposes. Black mustard might have abortifacient and menstrual stimulant effects. There is insufficient reliable information avai... Read the full pregnancy detail
Breastfeeding Use caution Food amounts are likely fine, but there is not enough safety data on medicinal use, so caution is advised.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Mitomycin and Black Mustard? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Mitomycin

Interactions in our licensed database are recorded against drug classes, not just single drug names. Mitomycin is filed under 3 classifications — antitumor antibiotics, topical drugs, oral drugs. Black Mustard has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Mitomycin’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Black Mustard Does Interact With Other Medications

Black Mustard has 86 moderate known drug interactions in our database — Mitomycin isn’t one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. Mitomycin)
Taking anything else?

Check Another of Your Medications Against Black Mustard

Covers the 2,830 medications we’ve checked against Black Mustard. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Black Mustard and Mitomycin May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Stomach pain / Vomiting Additional detail

    Black Mustard

    “Orally, taking very large amounts of black mustard seed can lead to vomiting, stomach pain, and diarrhea (18).”

    Black Mustard · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    Mitomycin

    Listed in the ADVERSE REACTIONS section of the FDA label for Mitomycin. Read the label on DailyMed ›

Reported for Black Mustard but not commonly for Mitomycin: shortness of breath and diarrhea.

Effects for Mitomycin come from the ADVERSE REACTIONS section of its FDA label; effects for Black Mustard come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Black Mustard in Pregnancy & Breastfeeding

Pregnancy Likely Unsafe

When used orally for medicinal purposes. Black mustard might have abortifacient and menstrual stimulant effects. There is insufficient reliable information available about the safety of black mustard for its other uses during pregnancy; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Mitomycin

This page covers Black Mustard only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Mitomycin page lists 26 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Acerola (moderate), Alpha-lipoic Acid (moderate), Coffee Charcoal (moderate) and Dimethylsulfoxide (dmso) (moderate).

By severity: 1 major · 15 moderate · 10 minor.

From our pharmacist’s overview on the Mitomycin page

“Activated charcoal is the entry to know first with mitomycin (Mutamycin, Mitosol, Jelmyto), a chemotherapy drug, because charcoal binds medications and can cut the amount the body receives, and it carries this list's only major rating. A weakened dose of a cancer treatment is a real loss, so I would treat these 26 interactions with gen…”

Reviewed by 2 · Jul 18, 2026

Open the Mitomycin interaction page

One more smart check

Taking Black Mustard as Part of a Dietary Supplement Product? Check It for Interactions

We hold 77 real supplement products containing Black Mustard, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Black Mustard. Even though Black Mustard itself has no known interaction with Mitomycin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Black Mustard and Mitomycin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Black Mustard
Top half

#555 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Mitomycin
Top 25%

#415 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Black Mustard reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Black Mustard and Mitomycin records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Black Mustard

What is Black Mustard?

Black Mustard
  • Culinary spice
  • Muscle and joint aches (topical plaster)
  • Chest congestion (chest rub or poultice)
  • Digestive upset
  • Antioxidant and anti-inflammatory support

Black mustard is best known as a pungent culinary spice and a traditional topical remedy for muscle aches and congestion. Solid human evidence for any specific health benefit is limited, and concentrated seed extracts or undiluted oil can irritate or burn the skin. Use it mainly as a food, and talk to a pharmacist or doctor before using it medicinally.

Brassica nigra · Brassicaceae · Seeds and seed oil; sometimes leaves · Whole or ground seeds (spice), mustard oil, poultices/plasters, powder

An interaction check asks whether these two react with each other — it does not ask whether Black Mustard is a good idea for someone in your situation. Here is what our Black Mustard record says about it on its own.

Black Mustard: dosing

There is no well-established standardized medicinal dose for black mustard. As a culinary spice, it is simply used to taste in cooking.For topical or supplement products, follow the directions on the product label, and do not leave mustard plasters on the skin for long periods.

From our Black Mustard monograph — the full record covers uses, side effects and every documented interaction.

Read the full Black Mustard monograph & all interactions
Medication

About Mitomycin

What Is Mitomycin Used For?

Brand names: Mutamycin, Mitosol, Jelmyto

Mitomycin (and its brand Mutamycin) is used intravenously in combination with other chemotherapy drugs to treat disseminated adenocarcinoma (a type of cancer that has spread) of the stomach or pancreas, when other treatments have not worked. It is not intended to replace surgery or radiation therapy.

Mitomycin is also the active ingredient in other products for different uses: Jelmyto treats low-grade upper tract urothelial cancer (cancer of the upper urinary tract); Zusduri treats recurrent low-grade intermediate-risk non-muscle invasive bladder cancer; and Mitosol is used as a surgical aid during certain glaucoma eye surgery. These are separate products with distinct indications and are not interchangeable with the intravenous injection form.

See full Mitomycin drug information
Keep checking

Other Drugs & Black Mustard

Browse every other medication we’ve checked against Black Mustard — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
86 Moderate 2,743 No interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Black Mustard page.

No interaction 2,743 drugs checked — show the list

We also checked Black Mustard against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Black Mustard list.

See the full Black Mustard interactions page
See every supplement checked against Mitomycin, ranked by severity
Evidence & sources

Black Mustard References

The 8 references that drive our Black Mustard monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  5. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  6. Anand, P., Murali, K. Y., Tandon, V., Chandra, R., and Murthy, P. S. Preliminary studies on antihyperglycemic effect of aqueous extract of Brassica nigra (L.) Koch in streptozotocin induced diabetic rats. Indian J Exp.Biol 2007;45(8):696-701.
  7. Anand, P., Murali, Y. K., Tandon, V., Murthy, P. S., and Chandra, R. Insulinotropic effect of aqueous extract of Brassica nigra improves glucose homeostasis in streptozotocin induced diabetic rats. Exp.Clin.Endocrinol.Diabetes 2009;117(6):251-256.
  8. Gulbransen, G. and Esernio-Jenssen, D. Aspiration of black mustard. J Toxicol.Clin.Toxicol. 1998;36(6):591-593. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Black Mustard and Mitomycin Together: Common Questions

Is it safe to take Black Mustard with Mitomycin?
We do not list a known interaction between Black Mustard and Mitomycin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Black Mustard and Mitomycin have any of the same side effects?
Yes — our sources link each of them separately to 2 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Black Mustard and Mitomycin combination checked?
Interactions in our licensed database are recorded against drug classes. Mitomycin is filed under 3 classifications, and Black Mustard has documented interactions with 1 drug class — none of Mitomycin's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Black Mustard interact with any other medications?
Yes. Black Mustard has 86 documented drug interactions in our database — Mitomycin is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Mitomycin interact with any supplements?
Yes. Mitomycin has documented interactions with 26 supplements in our database — Black Mustard is not one of them. The Mitomycin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Black Mustard monograph Uses, safety profile, and every drug interaction in one place Mitomycin drug information The full plain-English guide to this medication Mitomycin supplement interactions Every supplement checked against Mitomycin, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 8 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Mitomycin and Black Mustard?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.