Drug & supplement interaction

Caralluma + Esomeprazole Strontium

Esomeprazole Strontium brand name: Esomeprazole Strontium.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Caralluma and Esomeprazole Strontium in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Caralluma and Esomeprazole Strontium

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Esomeprazole Strontium and Caralluma in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Caralluma at all — not against Esomeprazole Strontium, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Caralluma safety at a glance

Caralluma overall Use caution Generally tolerated short-term in studies, but long-term safety is not well established.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid No reliable safety data, so avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Esomeprazole Strontium and Caralluma? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Caralluma and Esomeprazole Strontium May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Constipation / Bloating or gas reported in 10.5% of FDA reports for Esomeprazole Strontium Additional detail

    Caralluma

    “Orally, in clinical trials, side effects have included gastrointestinal upset, abdominal distention, flatulence, constipation, and gastritis. These side effects appeared to subside within the first two weeks of use and have also been reported in patients taking placebo.”

    Caralluma · Natural Medicines adverse-effect record, reported in constipation.

    Esomeprazole Strontium

    Listed in the ADVERSE REACTIONS section of the FDA label for Esomeprazole Strontium, and in voluntary FDA adverse-event reports. Read the label on DailyMed ›

Reported for Caralluma but not commonly for Esomeprazole Strontium: stomach upset and raised blood pressure.

Effects for Esomeprazole Strontium come from the ADVERSE REACTIONS section of its FDA label; effects for Caralluma come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 19 voluntary FDA FAERS reports for Esomeprazole Strontium that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Everything else you take

See Every Supplement That Interacts With Esomeprazole Strontium

This page covers Caralluma only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Esomeprazole Strontium page lists 154 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 102 moderate · 49 minor.

From our pharmacist’s overview on the Esomeprazole Strontium page

“People managing reflux or ulcers with esomeprazole strontium, a proton pump inhibitor, are often the same people reaching for herbal remedies and fiber, and this list of 154 interacting ingredients deserves a careful read, not a shrug. Three entries rate major, and all three, grapefruit, St.”

Reviewed by 2 · Jul 18, 2026

Open the Esomeprazole Strontium interaction page

One more smart check

Taking Caralluma as Part of a Dietary Supplement Product? Check It for Interactions

We hold 151 real supplement products containing Caralluma, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Caralluma. Even though Caralluma itself has no known interaction with Esomeprazole Strontium, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Caralluma and Esomeprazole Strontium Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Caralluma
Top half

#718 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Esomeprazole Strontium
Steady interest

#1,978 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Caralluma reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Caralluma and Esomeprazole Strontium records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Caralluma

What is Caralluma?

  • Appetite suppression
  • Weight management
  • Reducing waist circumference
  • Boosting energy/endurance

Caralluma fimbriata is an edible succulent plant from India that is marketed mainly as an appetite suppressant and weight-loss aid. Some small studies suggest it may modestly reduce appetite or waist size, but the overall evidence is limited and not strong. Talk to your pharmacist or doctor before trying it, and avoid it during pregnancy and breastfeeding.

Caralluma fimbriata · Apocynaceae · Aerial parts (stems) and whole-plant extract · Capsules, tablets, powder, standardized extract

An interaction check asks whether these two react with each other — it does not ask whether Caralluma is a good idea for someone in your situation. Here is what our Caralluma record says about it on its own.

Caralluma: dosing

There is no official or well-established standard dose for Caralluma. Studies have used standardized extracts, but the amounts varied, and there is not enough consistent evidence to recommend a specific milligram dose.The best approach is to follow the directions on the product label and not exceed the recommended amount. Because supplement strengths differ, it is a good idea to review the specific product with your pharmacist or doctor before using it.

From our Caralluma monograph — the full record covers uses, side effects and every documented interaction.

Read the full Caralluma monograph & all interactions
Medication

About Esomeprazole Strontium

Most-Reported Side Effects for Esomeprazole Strontium

From FAERS, the FDA’s public side-effect reporting system (19 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Diarrhea 3 reports
Fatigue 3 reports
Abdominal pain 2 reports
Asthenia 2 reports
Constipation 2 reports
Keep checking

Other Drugs & Caralluma

Browse every other medication we’ve checked against Caralluma — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Caralluma against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Caralluma list.

See the full Caralluma interactions page
See every supplement checked against Esomeprazole Strontium, ranked by severity
Evidence & sources

Caralluma References

The 1 references that drive our Caralluma monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Arora E, Khajuria V, Tandon VR, et al. To evaluate efficacy and safety of Caralluma fimbriata in overweight and obese patients: a randomized, single blinded, placebo control trial. Perspect Clin Res 2015;6(1):39-44. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Caralluma and Esomeprazole Strontium Together: Common Questions

Is it safe to take Caralluma with Esomeprazole Strontium?
We do not list a known interaction between Caralluma and Esomeprazole Strontium. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Caralluma and Esomeprazole Strontium have any of the same side effects?
Yes — our sources link each of them separately to 2 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Esomeprazole Strontium interact with any supplements?
Yes. Esomeprazole Strontium has documented interactions with 154 supplements in our database — Caralluma is not one of them. The Esomeprazole Strontium interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Caralluma monograph Uses, safety profile, and every drug interaction in one place Esomeprazole Strontium supplement interactions Every supplement checked against Esomeprazole Strontium, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Esomeprazole Strontium and Caralluma?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.