Drug & supplement interaction

Caraway + Brompheniramine, Phenylephrine, Phenyltoloxamine

Brompheniramine, Phenylephrine, Phenyltoloxamine brand name: Atrohist Sprinkle.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated July 2026 · Pair last verified Sep 13, 2026

The bottom line No known interaction

We found no known interaction between Caraway and Brompheniramine, Phenylephrine, Phenyltoloxamine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Caraway and Brompheniramine, Phenylephrine, Phenyltoloxamine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Brompheniramine, Phenylephrine, Phenyltoloxamine and Caraway in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Caraway safety at a glance

Caraway overall Use caution Generally safe in food amounts, but concentrated oil and supplement doses are less studied.

Pregnancy Possibly Unsafe When used in medicinal amounts. Caraway oil has been used to stimulate menstruation; avoid using. Read the full pregnancy detail

Breastfeeding Use caution Food amounts are likely fine, but safety of concentrated supplements while breastfeeding is not well studied.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Brompheniramine, Phenylephrine, Phenyltoloxamine and Caraway? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

How we checked

Why No Interaction Is Listed for Brompheniramine, Phenylephrine, Phenyltoloxamine

Interactions in our licensed database are recorded against drug classes, not just single drug names. Brompheniramine, Phenylephrine, Phenyltoloxamine is filed under 5 classifications — including alpha-adrenergic agonists, stimulant drugs, photosensitizing drugs. Caraway has documented interactions with 7 drug classes — the most serious being antidiabetes drugs (moderate), cns depressants (moderate) and diuretic drugs (moderate) — and none of Brompheniramine, Phenylephrine, Phenyltoloxamine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Caraway Does Interact With Other Medications

Caraway has 408 moderate, 5 minor known drug interactions in our database — Brompheniramine, Phenylephrine, Phenyltoloxamine isn’t one of them. If you take anything else, check it against the full list below.

Moderate 408 Minor 5 No known interaction 2,417 (incl. Brompheniramine, Phenylephrine, Phenyltoloxamine)

Taking anything else?

Check Another of Your Medications Against Caraway

Covers the 2,830 medications we’ve checked against Caraway. Pick one to open its full report.

What to actually watch for

What Caraway Itself Has Been Linked To

This is not an interaction — nothing below involves Brompheniramine, Phenylephrine, Phenyltoloxamine. It is the side-effect record for Caraway on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Caraway, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

Wheezing / An allergic reaction Worth acting on Additional detail
“Orally, an allergic reaction has been reported after use of caraway oil in combination with peppermint oil in a patient with a history of bronchial asthma. It is unclear if this adverse effect is due to caraway oil, peppermint oil, or the combination.”

Caraway · Natural Medicines adverse-effect record, reported in asthma.
1 source cited

96344. Rich G, Shah A, Koloski N, et al. A randomized placebo-controlled trial on the effects of Menthacarin, a proprietary peppermint- and caraway-oil-preparation, on symptoms and quality of life in patients with functional dyspepsia. Neurogastroenterol Motil 2 PubMed
Bloating or gas / Vomiting / Nausea Additional detail
“Orally, caraway oil, when used in combination with peppermint oil, may cause a substernal burning sensation, belching, nausea, and vomiting. It is unclear if these adverse effects are due to caraway oil, peppermint oil, or the combination. Peppermint oil, when used alone, has been reported to cause similar adverse effects.”

Caraway · Natural Medicines adverse-effect record, reported in nausea and vomiting.
4 sources cited

6741. May B, Kuntz HD, Kieser M, Kohler S. Efficacy of a fixed peppermint oil/caraway oil combination in non-ulcer dyspepsia. Arzneimittelforschung 1996;46:1149-53.

6742. Micklefield GH, Greving I, May B. Effects of peppermint oil and caraway oil on gastroduodenal motility. Phytother Res 2000;14:20-3. DOI

10075. May B, Kohler S, Schneider B. Efficacy and tolerability of a fixed combination of peppermint oil and caraway oil in patients suffering from functional dyspepsia. Aliment Pharmacol Ther 2000;14:1671-7. PubMed

96344. Rich G, Shah A, Koloski N, et al. A randomized placebo-controlled trial on the effects of Menthacarin, a proprietary peppermint- and caraway-oil-preparation, on symptoms and quality of life in patients with functional dyspepsia. Neurogastroenterol Motil 2 PubMed

Everything above comes from the Natural Medicines adverse-effect record for Caraway — expand a row for the licensed statement it rests on. We haven’t matched Brompheniramine, Phenylephrine, Phenyltoloxamine to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Brompheniramine, Phenylephrine, Phenyltoloxamine.

Special populations

Caraway in Pregnancy & Breastfeeding

Pregnancy Possibly Unsafe

When used in medicinal amounts. Caraway oil has been used to stimulate menstruation; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Brompheniramine, Phenylephrine, Phenyltoloxamine

This page covers Caraway only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Brompheniramine, Phenylephrine, Phenyltoloxamine page lists 87 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Ephedra (major), Peyote (major), Rauvolfia Vomitoria (major) and Sida Cordifolia (major).

By severity: 5 major · 68 moderate · 14 minor.

Open the Brompheniramine, Phenylephrine, Phenyltoloxamine interaction page

One more smart check

Taking Caraway as Part of a Dietary Supplement Product? Check It for Interactions

We hold 191 real supplement products containing Caraway, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Caraway. Even though Caraway itself has no known interaction with Brompheniramine, Phenylephrine, Phenyltoloxamine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Caraway and Brompheniramine, Phenylephrine, Phenyltoloxamine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Caraway

Top half

#401 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Brompheniramine, Phenylephrine, Phenyltoloxamine

Top half

#811 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Caraway reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Caraway and Brompheniramine, Phenylephrine, Phenyltoloxamine records this page draws on were last updated July 11, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Caraway

What is Caraway?

Digestive upset and bloating
Gas (flatulence)
Indigestion (dyspepsia)
Irritable bowel symptoms
Increasing breast milk (traditional)

Caraway is a common cooking spice that has long been used to ease gas, bloating, and indigestion. Some evidence suggests caraway oil—often combined with peppermint oil—may help with indigestion, but evidence for most other uses is limited. Food amounts are generally safe; concentrated oils and supplements should be used cautiously and discussed with your pharmacist or doctor.

Carum carvi · Apiaceae · Seeds (fruit) and essential oil · Whole or ground seeds, tea, capsules, essential oil, tincture

An interaction check asks whether these two react with each other — it does not ask whether Caraway is a good idea for someone in your situation. Here is what our Caraway record says about it on its own.

Caraway: dosing

There is no official, standardized dose of caraway for any health condition. Doses used in research and products vary widely depending on the form—seeds, tea, oil, or capsules.The best approach is to follow the directions on the product label and not exceed the recommended amount. Essential oil is highly concentrated and should only be used as directed.

From our Caraway monograph — the full record covers uses, side effects and every documented interaction.

Read the full Caraway monograph & all interactions

Keep checking

Other Drugs & Caraway

Browse every other medication we’ve checked against Caraway — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

408Moderate

5Minor

2,416No known interaction

408 Moderate 5 Minor 2,416 No interaction

Moderate

408 interactions

Showing 60 of 408 moderate interactions — see all 408 on the Caraway page.

Minor

5 interactions

No interaction 2,416 drugs checked — show the list

We also checked Caraway against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,416 medications checked with no known interaction — see the full Caraway list.

See the full Caraway interactions page

See every supplement checked against Brompheniramine, Phenylephrine, Phenyltoloxamine, ranked by severity

Evidence & sources

Caraway References

The 11 references that drive our Caraway monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
May B, Kuntz HD, Kieser M, Kohler S. Efficacy of a fixed peppermint oil/caraway oil combination in non-ulcer dyspepsia. Arzneimittelforschung 1996;46:1149-53.
Micklefield GH, Greving I, May B. Effects of peppermint oil and caraway oil on gastroduodenal motility. Phytother Res 2000;14:20-3. DOI
Herb Info Canada. Caraway website. www.herb.plant.org/caraway.htm (Accessed 11 September 2000).
May B, Kohler S, Schneider B. Efficacy and tolerability of a fixed combination of peppermint oil and caraway oil in patients suffering from functional dyspepsia. Aliment Pharmacol Ther 2000;14:1671-7. PubMed
Eddouks M, Lemhardri A, Michel JB. Caraway and caper: potential anti-hyperglycaemic plants in diabetic rats. J Ethnopharmacol 2004;94:143-8. PubMed
Sachin BS, Monica P, Sharma SC, et al. Pharmacokinetic interaction of some antitubercular drugs with caraway: implications in the enhancement of drug bioavailability. Hum Exp Toxicol. 2009;28(4):175-84. PubMed
Lahlou, S., Tahraoui, A., Israili, Z., and Lyoussi, B. Diuretic activity of the aqueous extracts of Carum carvi and Tanacetum vulgare in normal rats. J Ethnopharmacol. 4-4-2007;110(3):458-463. PubMed
de Sousa, D. P., Farias Nobrega, F. F., and de Almeida, R. N. Influence of the chirality of (R)-(-)- and (S)-(+)-carvone in the central nervous system: a comparative study. Chirality 5-5-2007;19(4):264-268.
Modu S, Gohla K Umar IA. The hypoglycaemic and hypocholrsterolaemic properties of black caraway (Carum carvi L.) oil in alloxan diabetic rats. Biokemistri (Nigeria) 1997;7:91-97.
Rich G, Shah A, Koloski N, et al. A randomized placebo-controlled trial on the effects of Menthacarin, a proprietary peppermint- and caraway-oil-preparation, on symptoms and quality of life in patients with functional dyspepsia. Neurogastroenterol Motil 2 PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Caraway and Brompheniramine, Phenylephrine, Phenyltoloxamine Together: Common Questions

Is it safe to take Caraway with Brompheniramine, Phenylephrine, Phenyltoloxamine?

We do not list a known interaction between Caraway and Brompheniramine, Phenylephrine, Phenyltoloxamine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

How was the Caraway and Brompheniramine, Phenylephrine, Phenyltoloxamine combination checked?

Interactions in our licensed database are recorded against drug classes. Brompheniramine, Phenylephrine, Phenyltoloxamine is filed under 5 classifications, and Caraway has documented interactions with 7 drug classes — none of Brompheniramine, Phenylephrine, Phenyltoloxamine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.

Does Caraway interact with any other medications?

Yes. Caraway has 413 documented drug interactions in our database — Brompheniramine, Phenylephrine, Phenyltoloxamine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Does Brompheniramine, Phenylephrine, Phenyltoloxamine interact with any supplements?

Yes. Brompheniramine, Phenylephrine, Phenyltoloxamine has documented interactions with 87 supplements in our database — Caraway is not one of them. The Brompheniramine, Phenylephrine, Phenyltoloxamine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Caraway monograph Uses, safety profile, and every drug interaction in one place Brompheniramine, Phenylephrine, Phenyltoloxamine supplement interactions Every supplement checked against Brompheniramine, Phenylephrine, Phenyltoloxamine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 11 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Brompheniramine, Phenylephrine, Phenyltoloxamine and Caraway?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.