Drug & supplement interaction

Chaulmoogra + Aripiprazole

Aripiprazole brand names: Abilify, Abilify Mycite, Abilify Maintena.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Chaulmoogra and Aripiprazole in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Chaulmoogra and Aripiprazole

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Aripiprazole and Chaulmoogra in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Chaulmoogra at all — not against Aripiprazole, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Chaulmoogra safety at a glance

Chaulmoogra overall Use caution Largely outdated remedy with limited modern safety data and a history of irritation and side effects.
Pregnancy Avoid Not enough safety information; avoid during pregnancy.
Breastfeeding Avoid Not enough safety information; avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Aripiprazole and Chaulmoogra? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Chaulmoogra and Aripiprazole May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • Shortness of breath Worth acting on Additional detail

    Chaulmoogra

    “Orally, ingestion of the seed can cause cough, dyspnea, laryngospasms, nephrotoxicity, visual disorders, head and muscle pain, and central paralysis (18).

    Topically, use can cause skin irritation (18).”

    Chaulmoogra · Natural Medicines adverse-effect record, reported in cough.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    Aripiprazole

    Listed in the ADVERSE REACTIONS section of the FDA label for Aripiprazole. Read the label on DailyMed ›

  • Cough / Muscle pain Additional detail

    Chaulmoogra

    Recorded for Chaulmoogra in the same Natural Medicines adverse-effect record shown under Shortness of breath above.

    Aripiprazole

    Listed in the ADVERSE REACTIONS section of the FDA label for Aripiprazole. Read the label on DailyMed ›

Reported for Chaulmoogra but not commonly for Aripiprazole: kidney problems.

Effects for Aripiprazole come from the ADVERSE REACTIONS section of its FDA label; effects for Chaulmoogra come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 125,626 voluntary FDA FAERS reports for Aripiprazole that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

From our Q&A

Questions About Chaulmoogra or Aripiprazole

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Chaulmoogra or Aripiprazole, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Aripiprazole

This page covers Chaulmoogra only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Aripiprazole page lists 250 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), American Hellebore (major), Arsenic (major) and Beer (major).

By severity: 17 major · 194 moderate · 39 minor.

From our pharmacist’s overview on the Aripiprazole page

“Aripiprazole (Abilify) is an antipsychotic prescribed for schizophrenia, bipolar disorder, and as an add-on for depression, and this is one of the lists I want readers to treat with real care. The biggest cluster changes how the body handles the drug itself: grapefruit can raise aripiprazole levels, while St.”

Reviewed by 2 · Jul 18, 2026

Open the Aripiprazole interaction page

How much people look this up

Where Chaulmoogra and Aripiprazole Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Chaulmoogra
Steady interest

#1,125 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Aripiprazole
Top 25%

#346 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Chaulmoogra reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Chaulmoogra and Aripiprazole records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Chaulmoogra

What is Chaulmoogra?

  • Leprosy (historical)
  • Skin conditions and rashes
  • Wound and sore care
  • Eczema and psoriasis (traditional)
  • Rheumatic complaints (traditional)

Chaulmoogra oil is an old herbal remedy famous for being the main treatment for leprosy before modern antibiotics. Today it has been replaced by safer, more effective drugs, and there is little reliable modern evidence to support its use. If you are considering it, talk to a pharmacist or doctor first, and avoid it during pregnancy and breastfeeding.

Hydnocarpus kurzii · Achariaceae · Seed oil (chaulmoogra oil) and seeds · Seed oil, topical preparations, and historically injectable oil derivatives

An interaction check asks whether these two react with each other — it does not ask whether Chaulmoogra is a good idea for someone in your situation. Here is what our Chaulmoogra record says about it on its own.

Chaulmoogra: dosing

There is no established, standardized dose for chaulmoogra in modern use, and it is not a recommended treatment today. Historical doses varied widely and were used under medical supervision in an era before modern drugs.If you find a product that contains chaulmoogra, follow the directions on the label and do not use it internally.

From our Chaulmoogra monograph — the full record covers uses, side effects and every documented interaction.

Read the full Chaulmoogra monograph & all interactions
Medication

About Aripiprazole

What Is Aripiprazole Used For?

Brand names: Abilify, Abilify Mycite, Abilify Maintena

Aripiprazole treats several mental health conditions. It is approved for schizophrenia, acute manic and mixed episodes of Bipolar I Disorder, and as an add-on to antidepressants for Major Depressive Disorder.

It is also used for irritability linked to autistic disorder and for Tourette's disorder — in both children and adults depending on the condition.

Most-Reported Side Effects for Aripiprazole

From FAERS, the FDA’s public side-effect reporting system (125,626 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Weight increased 8,027 reports
Anxiety 5,268 reports
Fatigue 4,437 reports
Suicidal ideation 4,154 reports
Depression 4,147 reports
See full Aripiprazole drug information
Keep checking

Other Drugs & Chaulmoogra

Browse every other medication we’ve checked against Chaulmoogra — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Chaulmoogra References

The 1 references that drive our Chaulmoogra monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Chaulmoogra and Aripiprazole Together: Common Questions

Is it safe to take Chaulmoogra with Aripiprazole?
We do not list a known interaction between Chaulmoogra and Aripiprazole. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Chaulmoogra and Aripiprazole have any of the same side effects?
Yes — our sources link each of them separately to 3 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Aripiprazole interact with any supplements?
Yes. Aripiprazole has documented interactions with 250 supplements in our database — Chaulmoogra is not one of them. The Aripiprazole interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Aripiprazole and Chaulmoogra?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.