Drug & supplement interaction

Chive + Ergoloid Mesylates

Ergoloid Mesylates brand name: Hydergine.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Chive and Ergoloid Mesylates in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Chive and Ergoloid Mesylates

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Ergoloid Mesylates and Chive in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Chive at all — not against Ergoloid Mesylates, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Chive safety at a glance

Chive overall Generally safe Chive is generally safe when eaten in normal food amounts.
Pregnancy Use caution Food amounts are likely fine, but avoid concentrated supplement doses since they are not well studied.
Breastfeeding Use caution Normal culinary amounts are likely fine; concentrated supplements lack safety data.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Ergoloid Mesylates and Chive? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Chive Itself Has Been Linked To

This is not an interaction — nothing below involves Ergoloid Mesylates. It is the side-effect record for Chive on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Chive, this list is the first place to look.

  • Stomach upset Additional detail

    “Orally, chive is generally well tolerated. Consuming large quantities of chive can lead to dyspepsia (18).

    Topically, chive has been rarely reported to cause contact dermatitis.”

    Chive · Natural Medicines adverse-effect record, reported in dermatitis.

    3 sources cited
    1. 4912. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
    2. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
    3. 41757. Roller, E., Meller, S., Homey, B., Ruzicka, T., and Neumann, N. J. [Contact dermatitis caused by spinach, hedge mustard and chives]. Hautarzt 2003;54(4):374-375.

    “Orally, large, unspecified quantities of chive can cause dyspepsia (18).”

    Chive · Natural Medicines adverse-effect record, reported in dyspepsia.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  • A skin rash Additional detail

    “Topically, immune-related contact dermatitis associated with chive and other vegetable exposure has been reported in a 54-year-old female vegetable farmer.”

    Chive · Natural Medicines adverse-effect record, reported in dermatitis.

    1 source cited
    1. 41757. Roller, E., Meller, S., Homey, B., Ruzicka, T., and Neumann, N. J. [Contact dermatitis caused by spinach, hedge mustard and chives]. Hautarzt 2003;54(4):374-375.

Everything above comes from the Natural Medicines adverse-effect record for Chive — expand a row for the licensed statement it rests on. We haven’t matched Ergoloid Mesylates to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Ergoloid Mesylates.

Everything else you take

See Every Supplement That Interacts With Ergoloid Mesylates

This page covers Chive only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ergoloid Mesylates page lists 20 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), Ephedra (moderate), Ergot (moderate) and European Mandrake (moderate).

By severity: 1 major · 10 moderate · 9 minor.

From our pharmacist’s overview on the Ergoloid Mesylates page

“Before you add any supplement while taking ergoloid mesylates (Hydergine), a medicine prescribed for age-related declines in memory and thinking, look hard at this list, because one item on it can effectively wipe out a dose. Activated charcoal, the only major-rated interaction of the 20 on file, binds medicines in the gut and can shar…”

Reviewed by 2 · Jul 18, 2026

Open the Ergoloid Mesylates interaction page

One more smart check

Taking Chive as Part of a Dietary Supplement Product? Check It for Interactions

We hold 23 real supplement products containing Chive, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Chive. Even though Chive itself has no known interaction with Ergoloid Mesylates, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Chive and Ergoloid Mesylates Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Chive
Steady interest

#794 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Ergoloid Mesylates
Top half

#1,249 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Chive reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Chive and Ergoloid Mesylates records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Chive

What is Chive?

  • Culinary flavoring
  • Digestive support
  • General immune support
  • Antimicrobial
  • Source of vitamins and antioxidants

Chive is a common kitchen herb in the onion and garlic family that is safe and nutritious when eaten as food. There is little human research supporting it as a medicine, so any health benefits beyond basic nutrition are not well proven. Enjoy it in cooking, and talk to your pharmacist or doctor before using concentrated chive supplements.

Allium schoenoprasum · Amaryllidaceae · Leaves (and sometimes flowers and bulbs) · Fresh or dried herb, culinary seasoning, powder, occasional supplement extracts

An interaction check asks whether these two react with each other — it does not ask whether Chive is a good idea for someone in your situation. Here is what our Chive record says about it on its own.

Chive: dosing

There is no established medicinal dose for chive. It is normally used in whatever amount tastes good in food.

From our Chive monograph — the full record covers uses, side effects and every documented interaction.

Read the full Chive monograph & all interactions
Medication

About Ergoloid Mesylates

What Is Ergoloid Mesylates Used For?

Brand name: Hydergine

  • This medication, a combination of several drugs that belong to a group of drugs called ergoloid mesylates, is used to relieve the signs and symptoms of decreased mental capacity due to the aging process.

  • This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

See full Ergoloid Mesylates drug information
Keep checking

Other Drugs & Chive

Browse every other medication we’ve checked against Chive — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Chive against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Chive list.

See the full Chive interactions page
See every supplement checked against Ergoloid Mesylates, ranked by severity
Evidence & sources

Chive References

The 3 references that drive our Chive monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  3. Roller, E., Meller, S., Homey, B., Ruzicka, T., and Neumann, N. J. [Contact dermatitis caused by spinach, hedge mustard and chives]. Hautarzt 2003;54(4):374-375.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Chive and Ergoloid Mesylates Together: Common Questions

Is it safe to take Chive with Ergoloid Mesylates?
We do not list a known interaction between Chive and Ergoloid Mesylates. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Ergoloid Mesylates interact with any supplements?
Yes. Ergoloid Mesylates has documented interactions with 20 supplements in our database — Chive is not one of them. The Ergoloid Mesylates interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Chive monograph Uses, safety profile, and every drug interaction in one place Ergoloid Mesylates drug information The full plain-English guide to this medication Ergoloid Mesylates supplement interactions Every supplement checked against Ergoloid Mesylates, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Ergoloid Mesylates and Chive?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.