Drug & supplement interaction

Chive + Nystatin

Nystatin brand names: Mycostatin, Nilstat.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Chive and Nystatin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Chive and Nystatin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Nystatin and Chive in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Chive at all — not against Nystatin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Chive safety at a glance

Chive overall Generally safe Chive is generally safe when eaten in normal food amounts.
Pregnancy Use caution Food amounts are likely fine, but avoid concentrated supplement doses since they are not well studied.
Breastfeeding Use caution Normal culinary amounts are likely fine; concentrated supplements lack safety data.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Nystatin and Chive? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Chive and Nystatin May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • A skin rash Additional detail

    Chive

    “Orally, chive is generally well tolerated. Consuming large quantities of chive can lead to dyspepsia (18).

    Topically, chive has been rarely reported to cause contact dermatitis.”

    Chive · Natural Medicines adverse-effect record, reported in dermatitis.

    3 sources cited
    1. 4912. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
    2. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
    3. 41757. Roller, E., Meller, S., Homey, B., Ruzicka, T., and Neumann, N. J. [Contact dermatitis caused by spinach, hedge mustard and chives]. Hautarzt 2003;54(4):374-375.

    “Topically, immune-related contact dermatitis associated with chive and other vegetable exposure has been reported in a 54-year-old female vegetable farmer.”

    Chive · Natural Medicines adverse-effect record, reported in dermatitis.

    1 source cited
    1. 41757. Roller, E., Meller, S., Homey, B., Ruzicka, T., and Neumann, N. J. [Contact dermatitis caused by spinach, hedge mustard and chives]. Hautarzt 2003;54(4):374-375.

    Nystatin

    Listed in the ADVERSE REACTIONS section of the FDA label for Nystatin. Read the label on DailyMed ›

Reported for Chive but not commonly for Nystatin: stomach upset.

Effects for Nystatin come from the ADVERSE REACTIONS section of its FDA label; effects for Chive come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

From our Q&A

Questions About Chive or Nystatin

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Chive or Nystatin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Nystatin

This page covers Chive only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Nystatin page lists 20 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 12 minor.

From our pharmacist’s overview on the Nystatin page

“Nystatin (Mycostatin, Nilstat) treats yeast infections such as oral thrush, and one of the 20 supplement ingredients on this list warrants real care. The single major-rated entry is activated charcoal, which can soak up the drug before it has a chance to work.”

Reviewed by 2 · Jul 18, 2026

Open the Nystatin interaction page

One more smart check

Taking Chive as Part of a Dietary Supplement Product? Check It for Interactions

We hold 23 real supplement products containing Chive, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Chive. Even though Chive itself has no known interaction with Nystatin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Chive and Nystatin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Chive
Steady interest

#832 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Nystatin
Steady interest

#2,180 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Chive reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Chive and Nystatin records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Chive

What is Chive?

  • Culinary flavoring
  • Digestive support
  • General immune support
  • Antimicrobial
  • Source of vitamins and antioxidants

Chive is a common kitchen herb in the onion and garlic family that is safe and nutritious when eaten as food. There is little human research supporting it as a medicine, so any health benefits beyond basic nutrition are not well proven. Enjoy it in cooking, and talk to your pharmacist or doctor before using concentrated chive supplements.

Allium schoenoprasum · Amaryllidaceae · Leaves (and sometimes flowers and bulbs) · Fresh or dried herb, culinary seasoning, powder, occasional supplement extracts

An interaction check asks whether these two react with each other — it does not ask whether Chive is a good idea for someone in your situation. Here is what our Chive record says about it on its own.

Chive: dosing

There is no established medicinal dose for chive. It is normally used in whatever amount tastes good in food.

From our Chive monograph — the full record covers uses, side effects and every documented interaction.

Read the full Chive monograph & all interactions
Medication

About Nystatin

What Is Nystatin Used For?

Brand names: Mycostatin, Nilstat

Nystatin treats infections caused by Candida yeast. The specific use depends on the form prescribed.

Topical creams, ointments, and powders (including brands like Mycostatin, Nystatin Cream, Klayesta, Nyamyc, Nystop, and Nystatin Topical Powder) treat Candida infections of the skin and mucous membranes. Nystatin Oral Suspension and Nystatin oral suspension treat candidiasis (yeast infection) in the mouth and oral cavity. Nystatin tablets are intended for non-esophageal mucous membrane Candida infections of the gastrointestinal tract.

Most-Reported Side Effects for Nystatin

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Nausea 2,063 reports
Fatigue 1,856 reports
Diarrhea 1,844 reports
Pneumonia 1,689 reports
Dyspnea 1,535 reports
See full Nystatin drug information
Keep checking

Other Drugs & Chive

Browse every other medication we’ve checked against Chive — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Chive References

The 3 references that drive our Chive monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  3. Roller, E., Meller, S., Homey, B., Ruzicka, T., and Neumann, N. J. [Contact dermatitis caused by spinach, hedge mustard and chives]. Hautarzt 2003;54(4):374-375.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Chive and Nystatin Together: Common Questions

Is it safe to take Chive with Nystatin?
We do not list a known interaction between Chive and Nystatin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Chive and Nystatin have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Nystatin interact with any supplements?
Yes. Nystatin has documented interactions with 20 supplements in our database — Chive is not one of them. The Nystatin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Nystatin and Chive?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.