Drug & supplement interaction

Clary Sage + Fosfomycin

Fosfomycin brand name: Monurol.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Clary Sage and Fosfomycin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Clary Sage and Fosfomycin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Fosfomycin and Clary Sage in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Clary Sage at all — not against Fosfomycin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Clary Sage safety at a glance

Clary Sage overall Use caution Generally considered safe as a diluted essential oil for aromatherapy, but it should not be taken by mouth.
Pregnancy Avoid Often discouraged in pregnancy because it is traditionally linked to uterine activity, so avoid it.
Breastfeeding Avoid There is not enough safety information, so it is best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Fosfomycin and Clary Sage? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Fosfomycin’s Own FDA Label Lists

This is not an interaction — none of it involves Clary Sage. These are the most notable effects listed in the ADVERSE REACTIONS section of Fosfomycin’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 4 of them are worth acting on rather than waiting out — marked below.

  • Low potassium Worth acting on
  • An irregular heartbeat Worth acting on
  • A low white blood cell count Worth acting on
  • An allergic reaction Worth acting on
  • Stomach pain
  • Diarrhea
  • Vomiting
  • Headache
  • Nausea

From the ADVERSE REACTIONS section of the FDA label for Fosfomycin. Read the label on DailyMed › Clary Sage’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Clary Sage side to compare — that is a limit of the record, not a statement that Clary Sage has no side effects.

Everything else you take

See Every Supplement That Interacts With Fosfomycin

This page covers Clary Sage only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Fosfomycin page lists 44 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Bacillus Coagulans (moderate), Bacillus Subtilis (moderate), Bifidobacterium Animalis Subsp. Lactis (moderate) and Bifidobacterium Bifidum (moderate).

By severity: 1 major · 33 moderate · 10 minor.

From our pharmacist’s overview on the Fosfomycin page

“Fosfomycin (Monurol) is often given as a single sachet to knock out a bladder infection, so you get one chance to absorb the full dose, and that is exactly where this list deserves real care. The clearest hazard is activated charcoal, which binds medicines in the gut and can cut how much fosfomycin your body actually takes in.”

Reviewed by 2 · Jul 18, 2026

Open the Fosfomycin interaction page

One more smart check

Taking Clary Sage as Part of a Dietary Supplement Product? Check It for Interactions

We hold 31 real supplement products containing Clary Sage, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Clary Sage. Even though Clary Sage itself has no known interaction with Fosfomycin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Clary Sage and Fosfomycin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Clary Sage
Steady interest

#1,260 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Fosfomycin
Steady interest

#2,018 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Clary Sage reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Clary Sage and Fosfomycin records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Clary Sage

What is Clary Sage?

  • Stress and anxiety
  • Menstrual cramps
  • Menopause symptoms
  • Aromatherapy and relaxation
  • Skin care

Clary sage is a Mediterranean herb most often used as an essential oil for aromatherapy and to ease stress or menstrual discomfort. Evidence for these uses is limited and mostly from small studies, and the oil should never be swallowed and should always be diluted before skin contact.

Salvia sclarea · Lamiaceae · Flowering tops and leaves (essential oil) · Essential oil, aromatherapy blends, diluted topical oils

An interaction check asks whether these two react with each other — it does not ask whether Clary Sage is a good idea for someone in your situation. Here is what our Clary Sage record says about it on its own.

Clary Sage: dosing

There is no official or standardized dose for clary sage, and it is not meant to be taken by mouth as a supplement.For aromatherapy, people typically add a few drops to a diffuser or dilute a small amount in a carrier oil before applying it to the skin.

From our Clary Sage monograph — the full record covers uses, side effects and every documented interaction.

Read the full Clary Sage monograph & all interactions
Medication

About Fosfomycin

What Is Fosfomycin Used For?

Brand name: Monurol

Fosfomycin is an antibiotic used to treat urinary tract infections (UTIs) caused by specific bacteria. The right form depends on how serious the infection is.

Oral forms (Fosfomycin Tromethamine and Monurol) are approved only for uncomplicated UTIs — also called acute cystitis — in women 18 and older, caused by E. coli or Enterococcus faecalis. They are not for kidney infections or abscesses around the kidney. Contepo (intravenous) is approved for adults 18 and older with complicated UTIs, including acute pyelonephritis (kidney infection), caused by susceptible E. coli or Klebsiella pneumoniae.

See full Fosfomycin drug information
Keep checking

Other Drugs & Clary Sage

Browse every other medication we’ve checked against Clary Sage — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Clary Sage References

The 2 references that drive our Clary Sage monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Ou, M. C., Hsu, T. F., Lai, A. C., Lin, Y. T., and Lin, C. C. Pain relief assessment by aromatic essential oil massage on outpatients with primary dysmenorrhea: a randomized, double-blind clinical trial. J Obstet.Gynaecol.Res 2012;38(5):817-822. PubMed
  2. Amirhosseini M, Dehghan M, Mangolian Shahrbabaki P, Pakmanesh H. Effectiveness of aromatherapy for relief of pain, nausea, and vomiting after percutaneous nephrolithotomy: a randomized controlled trial. Complement Med Res 2020:1-9. Online ahead of print. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Clary Sage and Fosfomycin Together: Common Questions

Is it safe to take Clary Sage with Fosfomycin?
We do not list a known interaction between Clary Sage and Fosfomycin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Fosfomycin interact with any supplements?
Yes. Fosfomycin has documented interactions with 44 supplements in our database — Clary Sage is not one of them. The Fosfomycin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Fosfomycin and Clary Sage?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.