Drug & supplement interaction

Clown's Mustard Plant + Oxaprozin

Oxaprozin brand name: Daypro.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Clown's Mustard Plant and Oxaprozin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Clown's Mustard Plant and Oxaprozin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Oxaprozin and Clown's Mustard Plant in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Clown's Mustard Plant at all — not against Oxaprozin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Clown's Mustard Plant safety at a glance

Clown's Mustard Pl... overall Use caution Generally well tolerated as part of standardized combination products, but stand-alone safety data are limited.
Pregnancy Avoid Not enough safety information; it is best to avoid during pregnancy.
Breastfeeding Avoid Not enough safety information; avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Oxaprozin and Clown's Mustard Plant? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Clown's Mustard Plant and Oxaprozin May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Nausea / Diarrhea / A skin rash reported in 6.8% of FDA reports for Oxaprozin Additional detail

    Clown's Mustard Plant

    “Orally, clown's mustard plant can cause nausea and diarrhea in some patients. Some patients might be hypersensitive to clown's mustard plant. There is one case of a facial rash following oral use.”

    Clown's Mustard Plant · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 7051. Steimer P. Iberogast therapy in gastroenterology. Der Krankenhaus Arzt 1983;56:1005-8.

    Oxaprozin

    Listed in the ADVERSE REACTIONS section of the FDA label for Oxaprozin, and in voluntary FDA adverse-event reports. Read the label on DailyMed ›

Effects for Oxaprozin come from the ADVERSE REACTIONS section of its FDA label; effects for Clown's Mustard Plant come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 883 voluntary FDA FAERS reports for Oxaprozin that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

From our Q&A

Questions About Clown's Mustard Plant or Oxaprozin

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Clown's Mustard Plant or Oxaprozin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Oxaprozin

This page covers Clown's Mustard Plant only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Oxaprozin page lists 52 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Beer (major), Siberian Cocklebur (major) and Wine (major).

By severity: 5 major · 35 moderate · 12 minor.

From our pharmacist’s overview on the Oxaprozin page

“I would put oxaprozin (Daypro), a long-acting NSAID prescribed for arthritis pain, in the read-carefully category. The interactions that concern me most pile onto the drug's own weak spots: alcohol, meaning the beer and wine entries below, raises the odds of stomach bleeding on any NSAID, and several kidney-stressing herbs can deepen t…”

Reviewed by 2 · Jul 18, 2026

Open the Oxaprozin interaction page

One more smart check

Taking Clown's Mustard Plant as Part of a Dietary Supplement Product? Check It for Interactions

We hold 3 real supplement products containing Clown's Mustard Plant, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Clown's Mustard Plant. Even though Clown's Mustard Plant itself has no known interaction with Oxaprozin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Clown's Mustard Plant and Oxaprozin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Clown's Mustard Plant
Steady interest

#816 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Oxaprozin
Steady interest

#2,441 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Clown's Mustard Plant reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Clown's Mustard Plant and Oxaprozin records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Clown's Mustard Plant

What is Clown's Mustard Plant?

  • Indigestion (dyspepsia)
  • Bloating and stomach fullness
  • Irritable bowel syndrome (IBS) symptoms
  • Heartburn and stomach discomfort
  • Gas and cramping

Clown's Mustard Plant (Iberis amara) is a small flowering herb best known as one ingredient in a popular European multi-herb digestive formula used for indigestion and IBS. Most of the supportive evidence comes from studies of that combination product, not the herb by itself, so it is hard to know how well Clown's Mustard alone works. If you want to try it, talk with your pharmacist or doctor first, especially if you are pregnant, breastfeeding, or have ongoing stomach problems.

Iberis amara · Brassicaceae · Whole flowering plant (often used fresh or dried), including seeds · Liquid herbal extract (a key ingredient in multi-herb combination products), tincture

An interaction check asks whether these two react with each other — it does not ask whether Clown's Mustard Plant is a good idea for someone in your situation. Here is what our Clown's Mustard Plant record says about it on its own.

Clown's Mustard Plant: dosing

There is no well-established stand-alone dose for Clown's Mustard Plant. In practice, it is almost always taken as part of a standardized liquid combination product, where the dose is set by the manufacturer.If you use a product containing this herb, follow the directions on the label and do not exceed the recommended amount.

From our Clown's Mustard Plant monograph — the full record covers uses, side effects and every documented interaction.

Read the full Clown's Mustard Plant monograph & all interactions
Medication

About Oxaprozin

What Is Oxaprozin Used For?

Brand name: Daypro

Oxaprozin is used to relieve the signs and symptoms of three types of arthritis: osteoarthritis, rheumatoid arthritis and juvenile rheumatoid arthritis.

The supplied labels for Coxanto (capsule), Oxaprozin capsules and Oxaprozin tablets all list these same three uses.

Most-Reported Side Effects for Oxaprozin

From FAERS, the FDA’s public side-effect reporting system (883 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Chronic kidney disease 82 reports
Drug hypersensitivity 61 reports
Nausea 60 reports
Renal failure 54 reports
Acute kidney injury 51 reports
See full Oxaprozin drug information Oxaprozin NDC codes and packages
Keep checking

Other Drugs & Clown's Mustard Plant

Browse every other medication we’ve checked against Clown's Mustard Plant — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Clown's Mustard Plant References

The 4 references that drive our Clown's Mustard Plant monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Holtmann G, Madisch A, Juergen H, et al. A double-blind, randomized, placebo-controlled trial on the effects of an herbal preparation in patients with functional dyspepsia [Abstract]. Ann Mtg Digestive Disease Week 1999 May.
  2. Steimer P. Iberogast therapy in gastroenterology. Der Krankenhaus Arzt 1983;56:1005-8.
  3. Madisch A, Holtmann G, Mayr G, et al. Treatment of functional dyspepsia with a herbal preparation. A double-blind, randomized, placebo-controlled, multicenter trial. Digestion 2004;69:45-52. PubMed
  4. Melzer J, Rosch W, Reichling J, et al. Meta-analysis: phytotherapy of functional dyspepsia with the herbal drug preparation STW 5 (Iberogast). Aliment Pharmacol Ther 2004;20:1279-87. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Clown's Mustard Plant and Oxaprozin Together: Common Questions

Is it safe to take Clown's Mustard Plant with Oxaprozin?
We do not list a known interaction between Clown's Mustard Plant and Oxaprozin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Clown's Mustard Plant and Oxaprozin have any of the same side effects?
Yes — our sources link each of them separately to 3 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Oxaprozin interact with any supplements?
Yes. Oxaprozin has documented interactions with 52 supplements in our database — Clown's Mustard Plant is not one of them. The Oxaprozin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Oxaprozin and Clown's Mustard Plant?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.