Oxaprozin

Generic name: Pronounced as (ox a proe' zin)
Brand names
  • Daypro®
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Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 03/15/2021

People who take nonsteroidal anti-inflammatory medications (NSAIDs) (other than aspirin) such as oxaprozin may have a higher risk of having a heart attack or a stroke than people who do not take these medications. These events may happen without warning and may cause death. This risk may be higher for people who take NSAIDs for a long time. Do not take an NSAID such as oxaprozin if you have recently had a heart attack, unless directed to do so by your doctor. Tell your doctor if you or anyone in your family has or has ever had heart disease, a heart attack, or a stroke, if you smoke, and if you have or have ever had high cholesterol, high blood pressure, or diabetes. Get emergency medical help right away if you experience any of the following symptoms: chest pain, shortness of breath, weakness in one part or side of the body, or slurred speech.

If you will be undergoing a coronary artery bypass graft (CABG; a type of heart surgery), you should not take oxaprozin right before or right after the surgery.

NSAIDs such as oxaprozin may cause ulcers, bleeding, or holes in the stomach or intestine. These problems may develop at any time during treatment, may happen without warning symptoms, and may cause death. The risk may be higher for people who take NSAIDs for a long time, are older in age, have poor health. or drink large amounts of alcohol while you are taking oxaprozin. Tell your doctor if you take any of the following medications: anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); aspirin; other NSAIDs such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); oral steroids such as dexamethasone, methylprednisolone (Medrol), and prednisone (Rayos); selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), and sertraline (Zoloft); or serotonin norepinephrine reuptake inhibitors (SNRIs) such as desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), and venlafaxine (Effexor XR). Also tell your doctor if you have or have ever had ulcers or bleeding in your stomach or intestines or other bleeding disorders. If you experience any of the following symptoms, stop taking oxaprozin and call your doctor: stomach pain, heartburn, vomiting a substance that is bloody or looks like coffee grounds, blood in the stool, or black and tarry stools.

Keep all appointments with your doctor and the laboratory. Your doctor will monitor your symptoms carefully and will probably order certain tests to check your body's response to oxaprozin. Be sure to tell your doctor how you are feeling so that your doctor can prescribe the right amount of medication to treat your condition with the lowest risk of serious side effects.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with oxaprozin and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer's website to obtain the Medication Guide.

Oxaprozin is used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints) and rheumatoid arthritis (arthritis caused by swelling of the lining of the joints). Oxaprozin is also used to relieve pain, tenderness, swelling, and stiffness caused by juvenile rheumatoid arthritis in children 6 years of age and older. Oxaprozin is in a class of medications called nonsteroidal anti-inflammatory medications (NSAIDs). It works by stopping the body's production of a substance that causes pain, fever, and inflammation.

Oxaprozin comes as a tablet to take by mouth. It is usually taken once or twice a day. Take oxaprozin at around the time(s) each day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take oxaprozin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking oxaprozin,

  • tell your doctor and pharmacist if you are allergic to oxaprozin, aspirin, or other NSAIDs such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn), any other medications, or any of the inactive ingredients in oxaprozin tablets. Ask your pharmacist for a list of the inactive ingredients.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin, in Lotrel), captopril, enalapril (Vasotec, in Vaseretic), fosinopril (Monopril), lisinopril (in Zestoretic), moexipril (Univasc), perindopril (Aceon, in Prestalia), quinapril (Accupril, in Quinaretic), ramipril (Altace), and trandolapril (Mavik, in Tarka); angiotensin receptor blockers (ARBs) such as azilsartan (Edarbi, in Edarbyclor), candesartan (Atacand, in Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, in Avalide), losartan (Cozaar, in Hyzaar), olmesartan (Benicar, in Azor, in Benicar HCT, in Tribenzor), telmisartan (Micardis, in Micardis HCT, in Twynsta), and valsartan (in Exforge HCT); beta blockers such as atenolol (Tenormin, in Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, in Dutoprol), nadolol (Corgard, in Corzide), and propranolol (Hemangeol, Inderal, Innopran); diuretics ('water pills'); glyburide (Glynase, Micronase); lithium (Lithobid); and methotrexate (Otrexup, Rasuvo, Trexall). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • tell your doctor if you have or ever had asthma, especially if you also have frequent stuffed or runny nose or nasal polyps; heart failure; swelling of the hands, feet, ankles, or lower legs; or kidney or liver disease.

  • tell your doctor if you are pregnant, plan to become pregnant; or are breast-feeding. Oxaprozin may harm the fetus and cause problems with delivery if it is taken around 20 weeks or later during pregnancy. Do not take oxaprozin around or after 20 weeks of pregnancy, unless you are told to do so by your doctor. If you become pregnant while taking oxaprozin, call your doctor.

  • talk to your doctor about the risks and benefits of taking oxaprozin if you are 65 years of age or older. Older adults should take lower doses of oxaprozin for only a short time period because higher doses used regularly may not be more effective and are more likely to cause serious side effects.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking oxaprozin.

  • plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Oxaprozin may make your skin sensitive to sunlight.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Oxaprozin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • diarrhea

    • constipation

    • vomiting

    • gas or bloating

    • drowsiness

    • difficulty sleeping

    • confusion

    • depression

    • dizziness

    • headache

    • ringing in the ears

  • Some side effects can be serious. If you experience any of the following symptoms or those mentioned in the IMPORTANT WARNING section, call your doctor immediately. Do not take any more oxaprozin until you speak to your doctor:

    • unexplained weight gain

    • shortness of breath or difficulty breathing

    • swelling in the abdomen, ankles, feet, or legs

    • fever

    • blisters

    • rash

    • itching

    • hives

    • swelling of the eyes, face, lips, tongue, throat, or hands

    • hoarseness

    • difficulty breathing or swallowing

    • yellowing of the skin or eyes

    • lack of energy

    • excessive tiredness

    • upset stomach

    • loss of appetite

    • pain in the upper right part of the stomach

    • flu-like symptoms

    • pale skin

    • fast heartbeat

    • cloudy, discolored, or bloody urine

    • back pain

    • difficult or painful urination

  • Oxaprozin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include the following:

  • lack of energy

  • drowsiness

  • upset stomach

  • vomiting

  • stomach pain

  • bloody, black, or tarry stools

  • vomiting a substance that is bloody or looks like coffee grounds

  • difficulty breathing

  • seizures

  • coma (loss of consciousness for a period of time)

Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking oxaprozin.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Moxifloxacin Moxifloxacin Oxaprozin may increase the neuroexcitatory activities of Moxifloxacin.
Alendronate Alendronate The risk or severity of adverse effects can be increased when Oxaprozin is combined with Alendronic acid.
Anagrelide Anagrelide The risk or severity of bleeding can be increased when Oxaprozin is combined with Anagrelide.
Candesartan Candesartan The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Candesartan is combined with Oxaprozin.
Cilostazol Cilostazol The risk or severity of bleeding can be increased when Oxaprozin is combined with Cilostazol.
Clopidogrel Clopidogrel The risk or severity of bleeding can be increased when Oxaprozin is combined with Clopidogrel.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) Oxaprozin may decrease the excretion rate of Conjugated estrogens which could result in a higher serum level.
Fenofibrate Fenofibrate Oxaprozin may decrease the excretion rate of Fenofibrate which could result in a higher serum level.
Guanfacine Guanfacine The therapeutic efficacy of Guanfacine can be decreased when used in combination with Oxaprozin.
Magnesium Hydroxide Magnesium Hydroxide Oxaprozin may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level.
Methylergonovine Methylergonovine The risk or severity of hypertension can be increased when Methylergometrine is combined with Oxaprozin.
Mycophenolate Mycophenolate Oxaprozin may decrease the excretion rate of Mycophenolic acid which could result in a higher serum level.
Naratriptan Naratriptan The risk or severity of hypertension can be increased when Naratriptan is combined with Oxaprozin.
Olsalazine Olsalazine The therapeutic efficacy of Olsalazine can be decreased when used in combination with Oxaprozin.
Penbutolol Penbutolol Oxaprozin may decrease the antihypertensive activities of Acebutolol.
Potassium Potassium Oxaprozin may decrease the excretion rate of Potassium cation which could result in a higher serum level.
Prednisone Prednisone The risk or severity of gastrointestinal irritation can be increased when Oxaprozin is combined with Prednisone.
Ranitidine Ranitidine Oxaprozin may decrease the excretion rate of Ranitidine which could result in a higher serum level.
Reserpine Reserpine The therapeutic efficacy of Reserpine can be decreased when used in combination with Oxaprozin.
Rizatriptan Rizatriptan Oxaprozin may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Sumatriptan Sumatriptan Oxaprozin may decrease the excretion rate of Sumatriptan which could result in a higher serum level.
Tacrolimus Tacrolimus The risk or severity of renal failure can be increased when Oxaprozin is combined with Tacrolimus.
Tiludronate Tiludronate The risk or severity of gastrointestinal bleeding can be increased when Oxaprozin is combined with Etidronic acid.
Triamcinolone Triamcinolone The risk or severity of gastrointestinal irritation can be increased when Triamcinolone is combined with Oxaprozin.
Zolmitriptan Zolmitriptan The risk or severity of hypertension can be increased when Zolmitriptan is combined with Oxaprozin.
Ampicillin Injection Ampicillin Injection Oxaprozin may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Doxycycline Injection Doxycycline Injection Oxaprozin may decrease the excretion rate of Doxycycline which could result in a higher serum level.
Fluconazole Injection Fluconazole Injection Oxaprozin may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Foscarnet Injection Foscarnet Injection The risk or severity of nephrotoxicity can be increased when Oxaprozin is combined with Foscarnet.
Hydromorphone Injection Hydromorphone Injection Oxaprozin may decrease the excretion rate of Hydromorphone which could result in a higher serum level.
Levofloxacin Injection Levofloxacin Injection Oxaprozin may decrease the excretion rate of Levofloxacin which could result in a higher serum level.
Meperidine Injection Meperidine Injection Oxaprozin may decrease the excretion rate of Meperidine which could result in a higher serum level.
Methylprednisolone Injection Methylprednisolone Injection The risk or severity of gastrointestinal irritation can be increased when Methylprednisolone is combined with Oxaprozin.
Metoclopramide Injection Metoclopramide Injection Oxaprozin may decrease the excretion rate of Metoclopramide which could result in a higher serum level.
Pamidronate Injection Pamidronate Injection The risk or severity of gastrointestinal bleeding can be increased when Oxaprozin is combined with Pamidronic acid.
Vancomycin Injection Vancomycin Injection Oxaprozin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Zidovudine Injection Zidovudine Injection The risk or severity of bleeding can be increased when Zidovudine is combined with Oxaprozin.
Altretamine Altretamine Oxaprozin may decrease the excretion rate of Amphetamine which could result in a higher serum level.
Cefuroxime Cefuroxime Cefuroxime may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Cyclosporine Cyclosporine The risk or severity of renal failure and hypertension can be increased when Oxaprozin is combined with Cyclosporine.
Enoxaparin Injection Enoxaparin Injection The risk or severity of bleeding and hemorrhage can be increased when Oxaprozin is combined with Enoxaparin.
Torsemide Torsemide The therapeutic efficacy of Torasemide can be decreased when used in combination with Oxaprozin.
Eprosartan Eprosartan The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Eprosartan is combined with Oxaprozin.
Meloxicam Meloxicam The risk or severity of adverse effects can be increased when Meloxicam is combined with Oxaprozin.
Pantoprazole Pantoprazole Oxaprozin may decrease the excretion rate of Pantoprazole which could result in a higher serum level.
Risedronate Risedronate The risk or severity of gastrointestinal bleeding can be increased when Oxaprozin is combined with Risedronic acid.
Sevelamer Sevelamer Sevelamer can cause a decrease in the absorption of Oxaprozin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Telmisartan Telmisartan The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Telmisartan is combined with Oxaprozin.
Temozolomide Temozolomide Oxaprozin may decrease the excretion rate of Temozolomide which could result in a higher serum level.
Zaleplon Zaleplon Oxaprozin may decrease the excretion rate of Zaleplon which could result in a higher serum level.
Linezolid Linezolid The risk or severity of hypertension can be increased when Linezolid is combined with Oxaprozin.
Pentosan Polysulfate Pentosan Polysulfate The risk or severity of bleeding and hemorrhage can be increased when Oxaprozin is combined with Pentosan polysulfate.
Trimipramine Trimipramine The risk or severity of hypertension can be increased when Trimipramine is combined with Oxaprozin.
Perindopril Perindopril The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Oxaprozin is combined with Perindopril.
Tenofovir Tenofovir Oxaprozin may increase the nephrotoxic activities of Tenofovir.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate The risk or severity of adverse effects can be increased when Oxaprozin is combined with Choline magnesium trisalicylate.
Dutasteride Dutasteride The risk or severity of hypertension can be increased when Oxaprozin is combined with Dutasteride.
Epinephrine Injection Epinephrine Injection The risk or severity of hypertension can be increased when Epinephrine is combined with Oxaprozin.
Eplerenone Eplerenone The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Oxaprozin is combined with Eplerenone.
Escitalopram Escitalopram The risk or severity of gastrointestinal bleeding can be increased when Escitalopram is combined with Oxaprozin.
Olmesartan Olmesartan The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Olmesartan is combined with Oxaprozin.
Zonisamide Zonisamide Oxaprozin may decrease the excretion rate of Zonisamide which could result in a higher serum level.
Aripiprazole Aripiprazole The risk or severity of hypertension can be increased when Oxaprozin is combined with Aripiprazole.
Atomoxetine Atomoxetine Oxaprozin may decrease the excretion rate of Atomoxetine which could result in a higher serum level.
Dexmethylphenidate Dexmethylphenidate The risk or severity of hypertension can be increased when Oxaprozin is combined with Dexmethylphenidate.
Atazanavir Atazanavir Atazanavir may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Almotriptan Almotriptan Oxaprozin may decrease the excretion rate of Almotriptan which could result in a higher serum level.
Eletriptan Eletriptan The risk or severity of hypertension can be increased when Eletriptan is combined with Oxaprozin.
Emtricitabine Emtricitabine Oxaprozin may decrease the excretion rate of Emtricitabine which could result in a higher serum level.
Memantine Memantine Oxaprozin may decrease the excretion rate of Memantine which could result in a higher serum level.
Tadalafil Tadalafil Oxaprozin may decrease the excretion rate of Tadalafil which could result in a higher serum level.
Frovatriptan Frovatriptan The risk or severity of hypertension can be increased when Oxaprozin is combined with Frovatriptan.
Gemifloxacin Gemifloxacin Oxaprozin may increase the neuroexcitatory activities of Gemifloxacin.
Protriptyline Protriptyline The risk or severity of hypertension can be increased when Protriptyline is combined with Oxaprozin.
Duloxetine Duloxetine The risk or severity of gastrointestinal bleeding can be increased when Duloxetine is combined with Oxaprozin.
Tinidazole Tinidazole Oxaprozin may decrease the excretion rate of Tinidazole which could result in a higher serum level.
Bosentan Bosentan The therapeutic efficacy of Bosentan can be decreased when used in combination with Oxaprozin.
Cefditoren Cefditoren Oxaprozin may decrease the excretion rate of Cefdinir which could result in a higher serum level.
Cyanocobalamin Injection Cyanocobalamin Injection Oxaprozin may decrease the excretion rate of Hydroxocobalamin which could result in a higher serum level.
Eszopiclone Eszopiclone Oxaprozin may decrease the excretion rate of Eszopiclone which could result in a higher serum level.
Ganciclovir Ganciclovir Oxaprozin may decrease the excretion rate of Ganciclovir which could result in a higher serum level.
Ribavirin Ribavirin Oxaprozin may decrease the excretion rate of Ribavirin which could result in a higher serum level.
Solifenacin Solifenacin The risk or severity of hypertension can be increased when Oxaprozin is combined with Solifenacin.
Valganciclovir Valganciclovir Oxaprozin may decrease the excretion rate of Valganciclovir which could result in a higher serum level.
Zoledronic Acid Injection Zoledronic Acid Injection The risk or severity of gastrointestinal bleeding can be increased when Oxaprozin is combined with Zoledronic acid.
Adefovir Adefovir Adefovir may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Dextroamphetamine Dextroamphetamine Oxaprozin may decrease the excretion rate of Amphetamine which could result in a higher serum level.
Ibandronate Ibandronate The risk or severity of gastrointestinal bleeding can be increased when Oxaprozin is combined with Ibandronate.
Isocarboxazid Isocarboxazid The risk or severity of hypertension can be increased when Oxaprozin is combined with Isocarboxazid.
Ramelteon Ramelteon Oxaprozin may decrease the excretion rate of Ramelteon which could result in a higher serum level.
Fentanyl Fentanyl Fentanyl may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Pregabalin Pregabalin Oxaprozin may decrease the excretion rate of Pregabalin which could result in a higher serum level.
Deferasirox Deferasirox The risk or severity of gastrointestinal bleeding and peptic ulcer can be increased when Oxaprozin is combined with Deferasirox.
Phenylephrine Phenylephrine The risk or severity of hypertension can be increased when Phenylephrine is combined with Oxaprozin.
Ranolazine Ranolazine Oxaprozin may decrease the excretion rate of Ranolazine which could result in a higher serum level.
Rasagiline Rasagiline Oxaprozin may decrease the excretion rate of Rasagiline which could result in a higher serum level.
Sitagliptin Sitagliptin Oxaprozin may decrease the excretion rate of Sitagliptin which could result in a higher serum level.
Varenicline Varenicline Oxaprozin may decrease the excretion rate of Varenicline which could result in a higher serum level.
Albuterol Albuterol Oxaprozin may decrease the excretion rate of Salbutamol which could result in a higher serum level.
Paliperidone Paliperidone Oxaprozin may decrease the excretion rate of Paliperidone which could result in a higher serum level.
Clofarabine Injection Clofarabine Injection Oxaprozin may decrease the excretion rate of Clofarabine which could result in a higher serum level.
Lubiprostone Lubiprostone Oxaprozin may decrease the excretion rate of Lubiprostone which could result in a higher serum level.
Aliskiren Aliskiren The risk or severity of renal failure and hypertension can be increased when Oxaprozin is combined with Aliskiren.
Bismuth Subsalicylate Bismuth Subsalicylate The therapeutic efficacy of Bismuth subsalicylate can be decreased when used in combination with Oxaprozin.
Pemetrexed Injection Pemetrexed Injection Oxaprozin may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Lisdexamfetamine Lisdexamfetamine The risk or severity of hypertension can be increased when Oxaprozin is combined with Lisdexamfetamine.
Sorafenib Sorafenib Oxaprozin may decrease the excretion rate of Sorafenib which could result in a higher serum level.
Levocetirizine Levocetirizine Oxaprozin may decrease the excretion rate of Levocetirizine which could result in a higher serum level.
Pegaptanib Injection Pegaptanib Injection Oxaprozin may decrease the excretion rate of Pegaptanib which could result in a higher serum level.
Azacitidine Injection Azacitidine Injection Oxaprozin may decrease the excretion rate of Azacitidine which could result in a higher serum level.
Lenalidomide Lenalidomide Oxaprozin may decrease the excretion rate of Lenalidomide which could result in a higher serum level.
Budesonide Budesonide The risk or severity of gastrointestinal irritation can be increased when Oxaprozin is combined with Budesonide.
Desmopressin Desmopressin The risk or severity of hypertension, hyponatremia, and water intoxication can be increased when Oxaprozin is combined with Desmopressin.
Doripenem Injection Doripenem Injection Oxaprozin may decrease the excretion rate of Doripenem which could result in a higher serum level.
Arsenic Trioxide Injection Arsenic Trioxide Injection Oxaprozin may decrease the excretion rate of Arsenic trioxide which could result in a higher serum level.
Desvenlafaxine Desvenlafaxine The risk or severity of gastrointestinal bleeding can be increased when Desvenlafaxine is combined with Oxaprozin.
Cevimeline Cevimeline Oxaprozin may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Nebivolol Nebivolol Oxaprozin may decrease the antihypertensive activities of Nebivolol.
Certolizumab Injection Certolizumab Injection Oxaprozin may decrease the excretion rate of Certolizumab pegol which could result in a higher serum level.
Daptomycin Injection Daptomycin Injection Oxaprozin may decrease the excretion rate of Daptomycin which could result in a higher serum level.
Methylnaltrexone Injection Methylnaltrexone Injection Oxaprozin may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level.
Midazolam Midazolam Oxaprozin may decrease the excretion rate of Midazolam which could result in a higher serum level.
Dexrazoxane Injection Dexrazoxane Injection Oxaprozin may decrease the excretion rate of Dexrazoxane which could result in a higher serum level.
Milnacipran Milnacipran The risk or severity of gastrointestinal bleeding can be increased when Milnacipran is combined with Oxaprozin.
Plerixafor Injection Plerixafor Injection Oxaprozin may decrease the excretion rate of Plerixafor which could result in a higher serum level.
Sodium Phosphate Sodium Phosphate The risk or severity of renal failure can be increased when Sodium phosphate, monobasic is combined with Oxaprozin.
Fesoterodine Fesoterodine Oxaprozin may decrease the excretion rate of Fesoterodine which could result in a higher serum level.
Betaxolol Betaxolol Oxaprozin may decrease the antihypertensive activities of Betaxolol.
Iloperidone Iloperidone The risk or severity of hypertension can be increased when Oxaprozin is combined with Iloperidone.
Prasugrel Prasugrel The risk or severity of bleeding and hemorrhage can be increased when Oxaprozin is combined with Prasugrel.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) Oxaprozin may increase the excretion rate of Tolvaptan which could result in a lower serum level and potentially a reduction in efficacy.
Dronedarone Dronedarone The risk or severity of hypertension can be increased when Oxaprozin is combined with Dronedarone.
Pralatrexate Injection Pralatrexate Injection Oxaprozin may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection Palonosetron Injection Oxaprozin may decrease the excretion rate of Palonosetron which could result in a higher serum level.
Saxagliptin Saxagliptin Oxaprozin may decrease the excretion rate of Saxagliptin which could result in a higher serum level.
Telavancin Injection Telavancin Injection Oxaprozin may decrease the excretion rate of Telavancin which could result in a higher serum level.
Topotecan Topotecan Oxaprozin may decrease the excretion rate of Topotecan which could result in a higher serum level.
Asenapine Asenapine The risk or severity of hypertension can be increased when Oxaprozin is combined with Asenapine.
Dabigatran Dabigatran The risk or severity of bleeding and hemorrhage can be increased when Oxaprozin is combined with Dabigatran.
Dalfampridine Dalfampridine Oxaprozin may decrease the excretion rate of Dalfampridine which could result in a higher serum level.
Ceftaroline Injection Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Lurasidone Lurasidone The risk or severity of hypertension can be increased when Oxaprozin is combined with Lurasidone.
Acetaminophen Injection Acetaminophen Injection The risk or severity of adverse effects can be increased when Acetaminophen is combined with Oxaprozin.
Vilazodone Vilazodone The risk or severity of hypertension can be increased when Oxaprozin is combined with Vilazodone.
Ipilimumab Injection Ipilimumab Injection Oxaprozin may decrease the excretion rate of Ipilimumab which could result in a higher serum level.
Denileukin Diftitox Injection Denileukin Diftitox Injection Oxaprozin may decrease the excretion rate of Aldesleukin which could result in a higher serum level.
Terbutaline Injection Terbutaline Injection Oxaprozin may decrease the excretion rate of Terbutaline which could result in a higher serum level.
Azilsartan Azilsartan The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Azilsartan medoxomil is combined with Oxaprozin.
Roflumilast Roflumilast Oxaprozin may decrease the excretion rate of Roflumilast which could result in a higher serum level.
Potassium Iodide Potassium Iodide Potassium Iodide may increase the hyperkalemic activities of Oxaprozin.
Rivaroxaban Rivaroxaban The risk or severity of bleeding and hemorrhage can be increased when Oxaprozin is combined with Rivaroxaban.
Ticagrelor Ticagrelor The risk or severity of bleeding and hemorrhage can be increased when Oxaprozin is combined with Ticagrelor.
Ruxolitinib Ruxolitinib Oxaprozin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Clobazam Clobazam Oxaprozin may decrease the excretion rate of Clobazam which could result in a higher serum level.
Deferiprone Deferiprone Oxaprozin may decrease the excretion rate of Deferiprone which could result in a higher serum level.
Cabergoline Cabergoline The risk or severity of hypertension can be increased when Cabergoline is combined with Oxaprozin.
Naloxone Injection Naloxone Injection Oxaprozin may decrease the excretion rate of Naloxone which could result in a higher serum level.
Ambrisentan Ambrisentan The therapeutic efficacy of Ambrisentan can be decreased when used in combination with Oxaprozin.
Fondaparinux Injection Fondaparinux Injection The risk or severity of bleeding and hemorrhage can be increased when Oxaprozin is combined with Fondaparinux.
Iloprost Iloprost The risk or severity of bleeding and hemorrhage can be increased when Oxaprozin is combined with Iloprost.
Enzalutamide Enzalutamide Oxaprozin may decrease the excretion rate of Enzalutamide which could result in a higher serum level.
Mirabegron Mirabegron Oxaprozin may decrease the excretion rate of Mirabegron which could result in a higher serum level.
Corticotropin, Repository Injection Corticotropin, Repository Injection The risk or severity of gastrointestinal irritation can be increased when Corticotropin is combined with Oxaprozin.
Teduglutide Injection Teduglutide Injection Oxaprozin may decrease the excretion rate of Teduglutide which could result in a higher serum level.
Icosapent Ethyl Icosapent Ethyl The risk or severity of bleeding can be increased when Oxaprozin is combined with Icosapent ethyl.
Alogliptin Alogliptin Oxaprozin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Pomalidomide Pomalidomide Oxaprozin may decrease the excretion rate of Pomalidomide which could result in a higher serum level.
Apixaban Apixaban The risk or severity of bleeding and hemorrhage can be increased when Oxaprozin is combined with Apixaban.
Canagliflozin Canagliflozin Oxaprozin may decrease the excretion rate of Canagliflozin which could result in a higher serum level.
Methazolamide Methazolamide Methazolamide may increase the excretion rate of Oxaprozin which could result in a lower serum level and potentially a reduction in efficacy.
Trametinib Trametinib Oxaprozin may decrease the excretion rate of Trametinib which could result in a higher serum level.
Levomilnacipran Levomilnacipran The risk or severity of gastrointestinal bleeding can be increased when Levomilnacipran is combined with Oxaprozin.
Ertapenem Injection Ertapenem Injection Oxaprozin may decrease the excretion rate of Ertapenem which could result in a higher serum level.
Vortioxetine Vortioxetine Oxaprozin may decrease the excretion rate of Vortioxetine which could result in a higher serum level.
Ketorolac Injection Ketorolac Injection The risk or severity of adverse effects can be increased when Ketorolac is combined with Oxaprozin.
Sofosbuvir Sofosbuvir Oxaprozin may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin Dapagliflozin Dapagliflozin may increase the excretion rate of Oxaprozin which could result in a lower serum level and potentially a reduction in efficacy.
Apremilast Apremilast Oxaprozin may decrease the excretion rate of Apremilast which could result in a higher serum level.
Droxidopa Droxidopa Oxaprozin may decrease the excretion rate of Droxidopa which could result in a higher serum level.
Testosterone Injection Testosterone Injection Oxaprozin may decrease the excretion rate of Testosterone which could result in a higher serum level.
Vorapaxar Vorapaxar The risk or severity of bleeding and hemorrhage can be increased when Oxaprozin is combined with Vorapaxar.
Edoxaban Edoxaban The risk or severity of bleeding and hemorrhage can be increased when Oxaprozin is combined with Edoxaban.
Methamphetamine Methamphetamine Oxaprozin may decrease the excretion rate of Metamfetamine which could result in a higher serum level.
Tasimelteon Tasimelteon Oxaprozin may decrease the excretion rate of Tasimelteon which could result in a higher serum level.
Riociguat Riociguat The therapeutic efficacy of Riociguat can be decreased when used in combination with Oxaprozin.
Risperidone Injection Risperidone Injection The risk or severity of hypertension can be increased when Risperidone is combined with Oxaprozin.
Haloperidol Injection Haloperidol Injection The therapeutic efficacy of Haloperidol can be increased when used in combination with Oxaprozin.
Amiloride Amiloride The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Oxaprozin is combined with Amiloride.
Macitentan Macitentan The therapeutic efficacy of Macitentan can be decreased when used in combination with Oxaprozin.
Flibanserin Flibanserin The risk or severity of hypertension can be increased when Oxaprozin is combined with Flibanserin.
Prednisolone Prednisolone The risk or severity of gastrointestinal irritation can be increased when Prednisolone is combined with Oxaprozin.
Brexpiprazole Brexpiprazole The risk or severity of hypertension can be increased when Oxaprozin is combined with Brexpiprazole.
Ziprasidone Injection Ziprasidone Injection The risk or severity of hypertension can be increased when Ziprasidone is combined with Oxaprozin.
Cariprazine Cariprazine The risk or severity of hypertension can be increased when Oxaprozin is combined with Cariprazine.
Penicillin G Procaine Injection Penicillin G Procaine Injection Oxaprozin may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level.
Ixazomib Ixazomib Oxaprozin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Lesinurad Lesinurad Oxaprozin may decrease the excretion rate of Lesinurad which could result in a higher serum level.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection Amphotericin B may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Dexamethasone Injection Dexamethasone Injection The risk or severity of gastrointestinal irritation can be increased when Dexamethasone is combined with Oxaprozin.
Defibrotide Injection Defibrotide Injection The risk or severity of bleeding and hemorrhage can be increased when Oxaprozin is combined with Defibrotide.
Brivaracetam Injection Brivaracetam Injection Oxaprozin may decrease the excretion rate of Brivaracetam which could result in a higher serum level.
Midodrine Midodrine The risk or severity of hypertension can be increased when Midodrine is combined with Oxaprozin.
Selexipag Selexipag The therapeutic efficacy of Selexipag can be decreased when used in combination with Oxaprozin.
Furosemide Injection Furosemide Injection The therapeutic efficacy of Furosemide can be decreased when used in combination with Oxaprozin.
Lixisenatide Injection Lixisenatide Injection Oxaprozin may decrease the excretion rate of Lixisenatide which could result in a higher serum level.
Doxepin (Insomnia) Doxepin (Insomnia) Oxaprozin may decrease the excretion rate of Doxepin which could result in a higher serum level.
Deutetrabenazine Deutetrabenazine Oxaprozin may decrease the excretion rate of Deutetrabenazine which could result in a higher serum level.
Valbenazine Valbenazine Oxaprozin may decrease the excretion rate of Valbenazine which could result in a higher serum level.
Deflazacort Deflazacort The risk or severity of gastrointestinal irritation can be increased when Deflazacort is combined with Oxaprozin.
Safinamide Safinamide The risk or severity of hypertension can be increased when Oxaprozin is combined with Safinamide.
Naldemedine Naldemedine Oxaprozin may decrease the excretion rate of Naldemedine which could result in a higher serum level.
Benznidazole Benznidazole Oxaprozin may decrease the excretion rate of Benznidazole which could result in a higher serum level.
Delafloxacin Delafloxacin Oxaprozin may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
Betrixaban Betrixaban The risk or severity of bleeding can be increased when Betrixaban is combined with Oxaprozin.
Ertugliflozin Ertugliflozin Ertugliflozin may increase the excretion rate of Oxaprozin which could result in a lower serum level and potentially a reduction in efficacy.
Apalutamide Apalutamide Oxaprozin may decrease the excretion rate of Apalutamide which could result in a higher serum level.
Baricitinib Baricitinib Oxaprozin may decrease the excretion rate of Baricitinib which could result in a higher serum level.
Lofexidine Lofexidine The therapeutic efficacy of Lofexidine can be decreased when used in combination with Oxaprozin.
Plazomicin Injection Plazomicin Injection Oxaprozin may decrease the excretion rate of Plazomicin which could result in a higher serum level.
Cannabidiol Cannabidiol The risk or severity of hypertension can be increased when Oxaprozin is combined with Cannabidiol.
Stiripentol Stiripentol Oxaprozin may decrease the excretion rate of Stiripentol which could result in a higher serum level.
Prucalopride Prucalopride Oxaprozin may decrease the excretion rate of Prucalopride which could result in a higher serum level.
Siponimod Siponimod The risk or severity of hypertension can be increased when Oxaprozin is combined with Siponimod.
Acyclovir Ophthalmic Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Caplacizumab-yhdp Injection Caplacizumab-yhdp Injection The risk or severity of bleeding can be increased when Oxaprozin is combined with Caplacizumab.
Solriamfetol Solriamfetol The risk or severity of hypertension can be increased when Solriamfetol is combined with Oxaprozin.
Pitolisant Pitolisant The risk or severity of adverse effects can be increased when Oxaprozin is combined with Pitolisant.
Phenytoin Injection Phenytoin Injection The serum concentration of Phenytoin can be increased when it is combined with Oxaprozin.
Selpercatinib Selpercatinib The risk or severity of hypertension can be increased when Oxaprozin is combined with Selpercatinib.
Naxitamab-gqgk Injection Naxitamab-gqgk Injection The risk or severity of hypertension can be increased when Oxaprozin is combined with Naxitamab.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The risk or severity of hyperkalemia can be increased when Oxaprozin is combined with Drospirenone.
Viloxazine Viloxazine Oxaprozin may decrease the excretion rate of Viloxazine which could result in a higher serum level.
Tobramycin Injection Tobramycin Injection Oxaprozin may decrease the excretion rate of Tobramycin which could result in a higher serum level.
Fenoprofen Fenoprofen The risk or severity of adverse effects can be increased when Fenoprofen is combined with Oxaprozin.
Indomethacin Indomethacin The risk or severity of adverse effects can be increased when Indomethacin is combined with Oxaprozin.
Mefenamic Acid Mefenamic Acid The risk or severity of adverse effects can be increased when Mefenamic acid is combined with Oxaprozin.
Naproxen Naproxen The risk or severity of adverse effects can be increased when Naproxen is combined with Oxaprozin.
Tolmetin Tolmetin The risk or severity of adverse effects can be increased when Tolmetin is combined with Oxaprozin.
Sulindac Sulindac The risk or severity of adverse effects can be increased when Sulindac is combined with Oxaprozin.
Trazodone Trazodone The risk or severity of gastrointestinal bleeding can be increased when Trazodone is combined with Oxaprozin.
Isotretinoin Isotretinoin Oxaprozin may decrease the excretion rate of Isotretinoin which could result in a higher serum level.
Sucralfate Sucralfate Oxaprozin may decrease the excretion rate of Sucralfate which could result in a higher serum level.
Floxuridine Floxuridine Oxaprozin may decrease the excretion rate of Floxuridine which could result in a higher serum level.
Metaxalone Metaxalone Oxaprozin may decrease the excretion rate of Metaxalone which could result in a higher serum level.
Methotrexate Injection Methotrexate Injection The serum concentration of Methotrexate can be increased when it is combined with Oxaprozin.
Methsuximide Methsuximide The risk or severity of hyperkalemia can be increased when Oxaprozin is combined with Methsuximide.
Diethylpropion Diethylpropion The risk or severity of hypertension can be increased when Diethylpropion is combined with Oxaprozin.
Chlorpromazine Chlorpromazine Oxaprozin may decrease the excretion rate of Chlorpromazine which could result in a higher serum level.
Diazepam Diazepam Oxaprozin may decrease the excretion rate of Diazepam which could result in a higher serum level.
Oxazepam Oxazepam Oxaprozin may decrease the excretion rate of Oxazepam which could result in a higher serum level.
Flurazepam Flurazepam Oxaprozin may decrease the excretion rate of Flurazepam which could result in a higher serum level.
Clorazepate Clorazepate Oxaprozin may decrease the excretion rate of Clorazepic acid which could result in a higher serum level.
Lorazepam Lorazepam Oxaprozin may decrease the excretion rate of Lorazepam which could result in a higher serum level.
Phenoxybenzamine Phenoxybenzamine The therapeutic efficacy of Phenoxybenzamine can be decreased when used in combination with Oxaprozin.
Carmustine Carmustine Oxaprozin may decrease the excretion rate of Carmustine which could result in a higher serum level.
Amantadine Amantadine Oxaprozin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Codeine Codeine Oxaprozin may decrease the excretion rate of Codeine which could result in a higher serum level.
Bromocriptine Bromocriptine The risk or severity of hypertension can be increased when Oxaprozin is combined with Bromocriptine.
Metaproterenol Metaproterenol The risk or severity of hypertension can be increased when Orciprenaline is combined with Oxaprozin.
Tranylcypromine Tranylcypromine The risk or severity of hypertension can be increased when Tranylcypromine is combined with Oxaprozin.
Phenelzine Phenelzine Oxaprozin may decrease the excretion rate of Phenelzine which could result in a higher serum level.
Ergoloid Mesylates Ergoloid Mesylates The risk or severity of hypertension can be increased when Oxaprozin is combined with Ergoloid mesylate.
Tetracycline Tetracycline Oxaprozin may decrease the excretion rate of Tetracycline which could result in a higher serum level.
Thioridazine Thioridazine The risk or severity of hypertension can be increased when Thioridazine is combined with Oxaprozin.
Trifluoperazine Trifluoperazine The risk or severity of hypertension can be increased when Trifluoperazine is combined with Oxaprozin.
Bleomycin Bleomycin Oxaprozin may decrease the excretion rate of Bleomycin which could result in a higher serum level.
Sulfadiazine Sulfadiazine Oxaprozin may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Methadone Methadone Oxaprozin may decrease the excretion rate of Methadone which could result in a higher serum level.
Benztropine Benztropine Oxaprozin may decrease the excretion rate of Benzatropine which could result in a higher serum level.
Colestipol Colestipol Colestipol can cause a decrease in the absorption of Oxaprozin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Maprotiline Maprotiline Oxaprozin may decrease the excretion rate of Maprotiline which could result in a higher serum level.
Ibuprofen Ibuprofen The risk or severity of adverse effects can be increased when Oxaprozin is combined with Ibuprofen.
Azathioprine Azathioprine Oxaprozin may decrease the excretion rate of Azathioprine which could result in a higher serum level.
Phentermine Phentermine The risk or severity of hypertension can be increased when Phentermine is combined with Oxaprozin.
Methylphenidate Methylphenidate Oxaprozin may decrease the excretion rate of Methylphenidate which could result in a higher serum level.
Amoxapine Amoxapine The risk or severity of hypertension can be increased when Amoxapine is combined with Oxaprozin.
Sulfasalazine Sulfasalazine The therapeutic efficacy of Sulfasalazine can be decreased when used in combination with Oxaprozin.
Hydrocortisone Hydrocortisone The risk or severity of gastrointestinal irritation can be increased when Hydrocortisone is combined with Oxaprozin.
Phenazopyridine Phenazopyridine The risk or severity of nephrotoxicity can be increased when Oxaprozin is combined with Phenazopyridine.
Carbamazepine Carbamazepine Oxaprozin may decrease the excretion rate of Carbamazepine which could result in a higher serum level.
Methyldopa Methyldopa The therapeutic efficacy of Methyldopa can be decreased when used in combination with Oxaprozin.
Clonidine Clonidine The therapeutic efficacy of Clonidine can be decreased when used in combination with Oxaprozin.
Prazosin Prazosin The therapeutic efficacy of Prazosin can be decreased when used in combination with Oxaprozin.
Hydralazine Hydralazine Oxaprozin may decrease the antihypertensive activities of Hydralazine.
Cimetidine Cimetidine Oxaprozin may decrease the excretion rate of Cimetidine which could result in a higher serum level.
Gentamicin Injection Gentamicin Injection Oxaprozin may decrease the excretion rate of Gentamicin which could result in a higher serum level.
Warfarin Warfarin The risk or severity of bleeding and hemorrhage can be increased when Oxaprozin is combined with Warfarin.
Clonazepam Clonazepam Oxaprozin may decrease the excretion rate of Clonazepam which could result in a higher serum level.
Loperamide Loperamide The risk or severity of hyperkalemia can be increased when Loperamide is combined with Oxaprozin.
Promethazine Promethazine Oxaprozin may decrease the excretion rate of Promethazine which could result in a higher serum level.
Meclofenamate Meclofenamate The risk or severity of adverse effects can be increased when Meclofenamic acid is combined with Oxaprozin.
Nitrofurantoin Nitrofurantoin Oxaprozin may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Digoxin Digoxin Oxaprozin may decrease the excretion rate of Digoxin which could result in a higher serum level.
Chloroquine Chloroquine Oxaprozin may decrease the excretion rate of Chloroquine which could result in a higher serum level.
Ethosuximide Ethosuximide The risk or severity of hyperkalemia can be increased when Ethosuximide is combined with Oxaprozin.
Triamterene Triamterene The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Oxaprozin is combined with Triamterene.
Sulfinpyrazone Sulfinpyrazone The risk or severity of bleeding can be increased when Oxaprozin is combined with Sulfinpyrazone.
Chlorothiazide Chlorothiazide The therapeutic efficacy of Chlorothiazide can be decreased when used in combination with Oxaprozin.
Chlorthalidone Chlorthalidone The therapeutic efficacy of Chlorthalidone can be decreased when used in combination with Oxaprozin.
Metolazone Metolazone The therapeutic efficacy of Metolazone can be decreased when used in combination with Oxaprozin.
Isosorbide Isosorbide Isosorbide may increase the excretion rate of Oxaprozin which could result in a lower serum level and potentially a reduction in efficacy.
Secobarbital Secobarbital Oxaprozin may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Desipramine Desipramine Oxaprozin may decrease the excretion rate of Desipramine which could result in a higher serum level.
Amitriptyline Amitriptyline Amitriptyline may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Imipramine Imipramine Imipramine may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Probenecid Probenecid Probenecid may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Quinidine Quinidine Oxaprozin may decrease the excretion rate of Quinidine which could result in a higher serum level.
Procainamide Procainamide Oxaprozin may decrease the excretion rate of Procainamide which could result in a higher serum level.
Isoniazid Isoniazid Oxaprozin may decrease the excretion rate of Isoniazid which could result in a higher serum level.
Pyrazinamide Pyrazinamide Oxaprozin may decrease the excretion rate of Pyrazinamide which could result in a higher serum level.
Disopyramide Disopyramide Oxaprozin may decrease the excretion rate of Disopyramide which could result in a higher serum level.
Valproic Acid Valproic Acid The protein binding of Valproic acid can be decreased when combined with Oxaprozin.
Butabarbital Butabarbital Oxaprozin may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Liothyronine Liothyronine Oxaprozin may decrease the excretion rate of Liothyronine which could result in a higher serum level.
Methimazole Methimazole Oxaprozin may decrease the excretion rate of Methimazole which could result in a higher serum level.
Chlorpropamide Chlorpropamide The protein binding of Chlorpropamide can be decreased when combined with Oxaprozin.
Tolbutamide Tolbutamide The protein binding of Tolbutamide can be decreased when combined with Oxaprozin.
Tolazamide Tolazamide The protein binding of Tolazamide can be decreased when combined with Oxaprozin.
Baclofen Baclofen Oxaprozin may decrease the excretion rate of Baclofen which could result in a higher serum level.
Ethambutol Ethambutol Oxaprozin may decrease the excretion rate of Ethambutol which could result in a higher serum level.
Methyclothiazide Methyclothiazide The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Oxaprozin.
Hydrochlorothiazide Hydrochlorothiazide The therapeutic efficacy of Hydrochlorothiazide can be decreased when used in combination with Oxaprozin.
Dantrolene Dantrolene The risk or severity of hyperkalemia can be increased when Oxaprozin is combined with Dantrolene.
Chlorzoxazone Chlorzoxazone Oxaprozin may decrease the excretion rate of Chlorzoxazone which could result in a higher serum level.
Pyridoxine Pyridoxine Oxaprozin may decrease the excretion rate of Pyridoxine which could result in a higher serum level.
Folic Acid Folic Acid Oxaprozin may decrease the excretion rate of Folic acid which could result in a higher serum level.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) Oxaprozin may decrease the antihypertensive activities of Propranolol.
Minoxidil Minoxidil The therapeutic efficacy of Minoxidil can be decreased when used in combination with Oxaprozin.
Pseudoephedrine Pseudoephedrine The risk or severity of hypertension can be increased when Pseudoephedrine is combined with Oxaprozin.
Nortriptyline Nortriptyline The risk or severity of hypertension can be increased when Nortriptyline is combined with Oxaprozin.
Spironolactone Spironolactone The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Oxaprozin is combined with Spironolactone.
Amphotericin B Injection Amphotericin B Injection Amphotericin B may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Phytonadione Phytonadione Oxaprozin may decrease the excretion rate of Phylloquinone which could result in a higher serum level.
Amikacin Injection Amikacin Injection Oxaprozin may decrease the excretion rate of Amikacin which could result in a higher serum level.
Nadolol Nadolol Oxaprozin may decrease the antihypertensive activities of Nadolol.
Cholestyramine Resin Cholestyramine Resin Cholestyramine can cause a decrease in the absorption of Oxaprozin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Allopurinol Allopurinol Oxaprozin may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Flavoxate Flavoxate Oxaprozin may decrease the excretion rate of Flavoxate which could result in a higher serum level.
Colchicine Colchicine Oxaprozin may decrease the excretion rate of Colchicine which could result in a higher serum level.
Cefaclor Cefaclor Cefaclor may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Cefadroxil Cefadroxil Oxaprozin may decrease the excretion rate of Cefadroxil which could result in a higher serum level.
Cefazolin Injection Cefazolin Injection Cefazolin may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Cephalexin Cephalexin Cephalexin may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Cefoxitin Injection Cefoxitin Injection Cefoxitin may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Dacarbazine Dacarbazine Oxaprozin may decrease the excretion rate of Dacarbazine which could result in a higher serum level.
Acetazolamide Acetazolamide Acetazolamide may increase the excretion rate of Oxaprozin which could result in a lower serum level and potentially a reduction in efficacy.
Cefotaxime Injection Cefotaxime Injection Cefotaxime may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Calcitonin Salmon Injection Calcitonin Salmon Injection Oxaprozin may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level.
Ketoconazole Ketoconazole The risk or severity of hyperkalemia can be increased when Oxaprozin is combined with Ketoconazole.
Pyrantel Pyrantel Oxaprozin may decrease the excretion rate of Pyrantel which could result in a higher serum level.
Captopril Captopril The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Oxaprozin is combined with Captopril.
Dipyridamole Dipyridamole The risk or severity of bleeding and hemorrhage can be increased when Oxaprozin is combined with Dipyridamole.
Isoxsuprine Isoxsuprine The risk or severity of hypertension can be increased when Oxaprozin is combined with Isoxsuprine.
Ethacrynic Acid Ethacrynic Acid The therapeutic efficacy of Etacrynic acid can be decreased when used in combination with Oxaprozin.
Colistimethate Injection Colistimethate Injection Colistimethate may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Metoprolol Metoprolol Oxaprozin may decrease the antihypertensive activities of Metoprolol.
Aspirin Aspirin The therapeutic efficacy of Acetylsalicylic acid can be decreased when used in combination with Oxaprozin.
Salsalate Salsalate The risk or severity of adverse effects can be increased when Oxaprozin is combined with Salsalate.
Alprazolam Alprazolam Oxaprozin may decrease the excretion rate of Alprazolam which could result in a higher serum level.
Temazepam Temazepam Oxaprozin may decrease the excretion rate of Temazepam which could result in a higher serum level.
Triazolam Triazolam Oxaprozin may decrease the excretion rate of Triazolam which could result in a higher serum level.
Dicyclomine Dicyclomine Oxaprozin may decrease the excretion rate of Dicyclomine which could result in a higher serum level.
Propantheline Propantheline Oxaprozin may decrease the excretion rate of Propantheline which could result in a higher serum level.
Trimethoprim Trimethoprim Oxaprozin may decrease the excretion rate of Trimethoprim which could result in a higher serum level.
Diltiazem Diltiazem The therapeutic efficacy of Diltiazem can be decreased when used in combination with Oxaprozin.
Nifedipine Nifedipine Oxaprozin may decrease the excretion rate of Nifedipine which could result in a higher serum level.
Timolol Timolol Oxaprozin may decrease the antihypertensive activities of Timolol.
Verapamil Verapamil Oxaprozin may decrease the excretion rate of Verapamil which could result in a higher serum level.
Atenolol Atenolol Oxaprozin may decrease the antihypertensive activities of Atenolol.
Pindolol Pindolol Oxaprozin may decrease the antihypertensive activities of Pindolol.
Cisplatin Injection Cisplatin Injection Oxaprozin may decrease the excretion rate of Cisplatin which could result in a higher serum level.
Diflunisal Diflunisal The therapeutic efficacy of Diflunisal can be decreased when used in combination with Oxaprozin.
Piroxicam Piroxicam The risk or severity of adverse effects can be increased when Piroxicam is combined with Oxaprozin.
Bumetanide Bumetanide The therapeutic efficacy of Bumetanide can be decreased when used in combination with Oxaprozin.
Glyburide Glyburide The protein binding of Glyburide can be decreased when combined with Oxaprozin.
Glipizide Glipizide The protein binding of Glipizide can be decreased when combined with Oxaprozin.
Indapamide Indapamide The therapeutic efficacy of Indapamide can be decreased when used in combination with Oxaprozin.
Amoxicillin Amoxicillin Oxaprozin may decrease the excretion rate of Amoxicillin which could result in a higher serum level.
Oxacillin Injection Oxacillin Injection Oxaprozin may decrease the excretion rate of Oxacillin which could result in a higher serum level.
Pentoxifylline Pentoxifylline The risk or severity of bleeding can be increased when Oxaprozin is combined with Pentoxifylline.
Pentamidine Injection Pentamidine Injection Pentamidine may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Ceftriaxone Injection Ceftriaxone Injection Oxaprozin may decrease the excretion rate of Ceftriaxone which could result in a higher serum level.
Labetalol Labetalol Oxaprozin may decrease the antihypertensive activities of Labetalol.
Auranofin Auranofin Oxaprozin may decrease the excretion rate of Auranofin which could result in a higher serum level.
Leuprolide Injection Leuprolide Injection Oxaprozin may decrease the excretion rate of Leuprolide which could result in a higher serum level.
Gemfibrozil Gemfibrozil Oxaprozin may decrease the excretion rate of Gemfibrozil which could result in a higher serum level.
Guanabenz Guanabenz The therapeutic efficacy of Guanabenz can be decreased when used in combination with Oxaprozin.
Dipivefrin Ophthalmic Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Ceftazidime Injection Ceftazidime Injection Ceftazidime may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Ketoprofen Ketoprofen The risk or severity of adverse effects can be increased when Oxaprozin is combined with Ketoprofen.
Cefotetan Injection Cefotetan Injection Oxaprozin may decrease the excretion rate of Cefotetan which could result in a higher serum level.
Enalapril Enalapril The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Oxaprozin is combined with Enalapril.
Flurbiprofen Flurbiprofen The risk or severity of adverse effects can be increased when Flurbiprofen is combined with Oxaprozin.
Amiodarone Amiodarone The risk or severity of hyperkalemia can be increased when Oxaprozin is combined with Amiodarone.
Aztreonam Injection Aztreonam Injection Oxaprozin may decrease the excretion rate of Aztreonam which could result in a higher serum level.
Buspirone Buspirone Oxaprozin may decrease the excretion rate of Buspirone which could result in a higher serum level.
Ciprofloxacin Ciprofloxacin Oxaprozin may decrease the excretion rate of Ciprofloxacin which could result in a higher serum level.
Mesalamine Mesalamine The therapeutic efficacy of Mesalazine can be decreased when used in combination with Oxaprozin.
Diclofenac Diclofenac The risk or severity of adverse effects can be increased when Diclofenac is combined with Oxaprozin.
Fluoxetine Fluoxetine The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Oxaprozin.
Nimodipine Nimodipine The therapeutic efficacy of Nimodipine can be decreased when used in combination with Oxaprozin.
Clozapine Clozapine Oxaprozin may decrease the excretion rate of Clozapine which could result in a higher serum level.
Estazolam Estazolam Oxaprozin may decrease the excretion rate of Estazolam which could result in a higher serum level.
Ofloxacin Ofloxacin Oxaprozin may increase the neuroexcitatory activities of Ofloxacin.
Didanosine Didanosine Oxaprozin may decrease the excretion rate of Didanosine which could result in a higher serum level.
Pentostatin Injection Pentostatin Injection Oxaprozin may decrease the excretion rate of Pentostatin which could result in a higher serum level.
Benazepril Benazepril The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Oxaprozin is combined with Benazepril.
Etodolac Etodolac The risk or severity of adverse effects can be increased when Etodolac is combined with Oxaprozin.
Felodipine Felodipine The therapeutic efficacy of Felodipine can be decreased when used in combination with Oxaprozin.
Fosinopril Fosinopril The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Oxaprozin is combined with Fosinopril.
Nabumetone Nabumetone The risk or severity of adverse effects can be increased when Nabumetone is combined with Oxaprozin.
Quinapril Quinapril The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Oxaprozin is combined with Quinapril.
Ramipril Ramipril The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Oxaprozin is combined with Ramipril.
Amlodipine Amlodipine Oxaprozin may decrease the antihypertensive activities of Amlodipine.
Itraconazole Itraconazole The risk or severity of hyperkalemia can be increased when Oxaprozin is combined with Itraconazole.
Lisinopril Lisinopril The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Oxaprozin is combined with Lisinopril.
Sotalol Sotalol Oxaprozin may decrease the antihypertensive activities of Sotalol.
Bisoprolol Bisoprolol Oxaprozin may decrease the antihypertensive activities of Bisoprolol.
Doxazosin Doxazosin The therapeutic efficacy of Doxazosin can be decreased when used in combination with Oxaprozin.
Terazosin Terazosin The therapeutic efficacy of Terazosin can be decreased when used in combination with Oxaprozin.
Isradipine Isradipine The therapeutic efficacy of Isradipine can be decreased when used in combination with Oxaprozin.
Venlafaxine Venlafaxine Venlafaxine may increase the antiplatelet activities of Oxaprozin.
Fluvoxamine Fluvoxamine The risk or severity of gastrointestinal bleeding can be increased when Oxaprozin is combined with Fluvoxamine.
Nefazodone Nefazodone The risk or severity of gastrointestinal bleeding can be increased when Oxaprozin is combined with Nefazodone.
Lamotrigine Lamotrigine Oxaprozin may decrease the excretion rate of Lamotrigine which could result in a higher serum level.
Losartan Losartan The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Losartan is combined with Oxaprozin.
Valacyclovir Valacyclovir Valaciclovir may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Tramadol Tramadol Oxaprozin may decrease the excretion rate of Tramadol which could result in a higher serum level.
Carboplatin Injection Carboplatin Injection Carboplatin may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Moexipril Moexipril The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Oxaprozin is combined with Moexipril.
Ifosfamide Injection Ifosfamide Injection Oxaprozin may decrease the excretion rate of Ifosfamide which could result in a higher serum level.
Nicardipine Nicardipine The therapeutic efficacy of Nicardipine can be decreased when used in combination with Oxaprozin.
Bupropion Bupropion Oxaprozin may decrease the excretion rate of Bupropion which could result in a higher serum level.
Ticlopidine Ticlopidine The risk or severity of bleeding can be increased when Oxaprozin is combined with Ticlopidine.
Metformin Metformin Oxaprozin may decrease the excretion rate of Metformin which could result in a higher serum level.
Dalteparin Injection Dalteparin Injection The risk or severity of bleeding and hemorrhage can be increased when Oxaprozin is combined with Dalteparin.
Nisoldipine Nisoldipine The therapeutic efficacy of Nisoldipine can be decreased when used in combination with Oxaprozin.
Lamivudine Lamivudine Oxaprozin may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Acarbose Acarbose Oxaprozin may decrease the excretion rate of Acarbose which could result in a higher serum level.
Glimepiride Glimepiride The protein binding of Glimepiride can be decreased when combined with Oxaprozin.
Gemcitabine Injection Gemcitabine Injection Oxaprozin may decrease the excretion rate of Gemcitabine which could result in a higher serum level.
Cidofovir Injection Cidofovir Injection Cidofovir may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Meropenem Injection Meropenem Injection Oxaprozin may decrease the excretion rate of Meropenem which could result in a higher serum level.
Clomipramine Clomipramine Oxaprozin may decrease the excretion rate of Clomipramine which could result in a higher serum level.
Fosfomycin Fosfomycin Oxaprozin may decrease the excretion rate of Fosfomycin which could result in a higher serum level.
Mirtazapine Mirtazapine The risk or severity of hypertension can be increased when Mirtazapine is combined with Oxaprozin.
Trandolapril Trandolapril The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Oxaprozin is combined with Trandolapril.
Topiramate Topiramate Oxaprozin may decrease the excretion rate of Topiramate which could result in a higher serum level.
Valsartan Valsartan The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Valsartan is combined with Oxaprozin.
Pramipexole Pramipexole Oxaprozin may decrease the excretion rate of Pramipexole which could result in a higher serum level.
Carvedilol Carvedilol Oxaprozin may decrease the antihypertensive activities of Carvedilol.
Nilutamide Nilutamide Oxaprozin may decrease the excretion rate of Nilutamide which could result in a higher serum level.
Flutamide Flutamide Oxaprozin may decrease the excretion rate of Flutamide which could result in a higher serum level.
Selegiline Selegiline The risk or severity of hypertension can be increased when Oxaprozin is combined with Selegiline.
Sertraline Sertraline The risk or severity of bleeding can be increased when Sertraline is combined with Oxaprozin.
Propafenone Propafenone Oxaprozin may decrease the antihypertensive activities of Propafenone.
Irbesartan Irbesartan The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Irbesartan is combined with Oxaprozin.
Tamsulosin Tamsulosin Oxaprozin may decrease the excretion rate of Tamsulosin which could result in a higher serum level.
Finasteride Finasteride The risk or severity of hypertension can be increased when Oxaprozin is combined with Finasteride.
Quetiapine Quetiapine Oxaprozin may decrease the excretion rate of Quetiapine which could result in a higher serum level.
Cefepime Injection Cefepime Injection Cefepime may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Cefprozil Cefprozil Cefprozil may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Cefpodoxime Cefpodoxime Cefpodoxime may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Cetirizine Cetirizine Oxaprozin may decrease the excretion rate of Cetirizine which could result in a higher serum level.
Paroxetine Paroxetine The risk or severity of gastrointestinal bleeding can be increased when Paroxetine is combined with Oxaprozin.
Tolcapone Tolcapone Oxaprozin may decrease the excretion rate of Tolcapone which could result in a higher serum level.
Citalopram Citalopram The risk or severity of gastrointestinal bleeding can be increased when Citalopram is combined with Oxaprozin.
Capecitabine Capecitabine Oxaprozin may decrease the excretion rate of Capecitabine which could result in a higher serum level.
Abacavir Abacavir Oxaprozin may decrease the excretion rate of Abacavir which could result in a higher serum level.
Celecoxib Celecoxib The risk or severity of adverse effects can be increased when Celecoxib is combined with Oxaprozin.
Rosiglitazone Rosiglitazone Oxaprozin may decrease the excretion rate of Rosiglitazone which could result in a higher serum level.
Tolterodine Tolterodine Oxaprozin may decrease the excretion rate of Tolterodine which could result in a higher serum level.
Oseltamivir Oseltamivir Oxaprozin may decrease the excretion rate of Oseltamivir which could result in a higher serum level.
Colesevelam Colesevelam Colesevelam can cause a decrease in the absorption of Oxaprozin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Balsalazide Balsalazide The therapeutic efficacy of Balsalazide can be decreased when used in combination with Oxaprozin.
Nateglinide Nateglinide Oxaprozin may decrease the excretion rate of Nateglinide which could result in a higher serum level.
Rabeprazole Rabeprazole Oxaprozin may decrease the excretion rate of Rabeprazole which could result in a higher serum level.

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