Oxaprozin
Oxaprozin is a nonsteroidal anti-inflammatory drug (NSAID) taken by mouth to relieve the signs and symptoms of osteoarthritis, rheumatoid arthritis and juvenile rheumatoid arthritis.
🧬 Where this information comes from
The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 11 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →
Oxaprozin (Daypro) is an NSAID (nonsteroidal anti-inflammatory drug) for osteoarthritis and adult or juvenile rheumatoid arthritis that blocks the COX-1 and COX-2 enzymes, cutting the prostaglandins behind pain and inflammation; available as a generic and on the market since about 1992, it is a less common, once-a-day alternative to naproxen or ibuprofen. Like most NSAIDs it is usually well tolerated, with indigestion, heartburn, nausea or mild ankle swelling the complaints people notice most. Its boxed warning covers heart attack, stroke and stomach or intestinal bleeding that can strike without warning, so use the lowest dose that works for the shortest time and treat black stools or chest pain as urgent.
Clinical pearls
- Capsules and tablets are not interchangeable, so do not swap one for the other without a new prescription.
- Do not add ibuprofen, naproxen or pain-relief aspirin, and it does not replace low-dose aspirin for heart protection.
- With lithium, digoxin, methotrexate or warfarin, oxaprozin can push up levels, toxicity or bleeding, so every prescriber needs to know.
- It must not be used around CABG heart surgery, and should be avoided from about 30 weeks of pregnancy onward.
⚠️ FDA Boxed Warning — the FDA’s strongest safety alert ▾
Oxaprozin and other NSAIDs can increase the risk of heart attack and stroke, which can be fatal. This risk can start early in treatment and may grow the longer you take it. Oxaprozin must not be used around CABG heart surgery.
NSAIDs can also cause bleeding, ulcers or holes (perforation) in the stomach or intestines, which can be fatal. This can happen at any time and often without warning symptoms. Older adults and people with a past stomach ulcer or GI bleeding are at greatest risk.
Patient Information Guide A plain-language walkthrough of Oxaprozin, written from its FDA label.
What Oxaprozin Is Used For
▾
Oxaprozin is used for three types of arthritis.
- Osteoarthritis: relief of signs and symptoms (Coxanto capsules, Oxaprozin capsules and Oxaprozin tablets).
- Rheumatoid arthritis: relief of signs and symptoms (Coxanto capsules, Oxaprozin capsules and Oxaprozin tablets).
- Juvenile rheumatoid arthritis: relief of signs and symptoms (Coxanto capsules, Oxaprozin capsules and Oxaprozin tablets).
How Oxaprozin Works
▾
Oxaprozin is an NSAID with pain-relieving, anti-inflammatory and fever-reducing properties. It blocks the COX-1 and COX-2 enzymes that make prostaglandins. Prostaglandins make nerves more sensitive to pain and promote inflammation, so lowering them in the body's tissues eases arthritis symptoms.
Oxaprozin Dosage
▾
Oxaprozin is taken by mouth, usually once a day. The goal is the lowest effective amount for the shortest time. Your prescriber adjusts it to how you respond.
- Coxanto and Oxaprozin capsules and Oxaprozin tablets are different formulations and are not interchangeable.
- For juvenile rheumatoid arthritis (ages 6 to 16), the amount depends on body weight.
- For Oxaprozin tablets, people with low body weight or severe kidney impairment or on dialysis start at a lower amount.
- Food may slow absorption but does not change how much is absorbed.
Follow your prescriber's directions and your product's label, including for missed doses.
Dosing details from the FDA-approved label
From the Oxaprozin prescribing information (“Dosage and Administration”). Doses are set by your prescriber for your product, condition, kidney function and age — never change a dose on your own.
- Osteoarthritis (OA)
- 1200 mg (two 600 mg tablets) given orally once a day
- Capsule labels: 1,200 mg (four 300 mg capsules) given orally once a day
- Maximum: Adults: 1800 mg (26 mg/kg, whichever is lower) in divided doses (tablet label); 1,200 mg a day (Coxanto capsule label)
- Individualize to lowest effective dose; start at 600 mg once daily if low body weight or severe renal impairment/dialysis
- Rheumatoid arthritis (RA)
- 1200 mg (two 600 mg tablets) given orally once a day
- Capsule labels: 1,200 mg (four 300 mg capsules) given orally once a day
- Maximum: Adults: 1800 mg (26 mg/kg, whichever is lower) in divided doses (tablet label); 1,200 mg a day (Coxanto capsule label)
- Individualize to lowest effective dose; start at 600 mg once daily if low body weight or severe renal impairment/dialysis
- Juvenile rheumatoid arthritis (JRA), patients 6 to 16 years, 22 to 31 kg
- 600 mg once daily
- Maximum: In children, doses greater than 1200 mg have not been studied
- Dose based on body weight
- JRA, patients 32 to 54 kg
- 900 mg once daily
- Maximum: In children, doses greater than 1200 mg have not been studied
- Dose based on body weight
- JRA, patients 55 kg or greater
- 1200 mg once daily
- Maximum: In children, doses greater than 1200 mg have not been studied
- Dose based on body weight
- Patients with low body weight, or severe renal impairment or on dialysis
- Initiate therapy with 600 mg once daily
- If relief is insufficient, may be cautiously increased to 1200 mg
- Increase only with close monitoring
- Adults needing quick onset of action (tablet label)
- One-time loading dose of 1200 to 1800 mg
- Maximum: Not to exceed 26 mg/kg
- Doses larger than 1200 mg/day chronically reserved for patients weighing more than 50 kg with normal renal and hepatic function, low peptic ulcer risk
Read the label’s full dosing text
DOSAGE & ADMINISTRATION SECTION Carefully consider the potential benefits and risks of oxaprozin tablet, USP and other treatment options before deciding to use oxaprozin tablet, USP. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals (see WARNINGS ). After observing the response to initial therapy with oxaprozin tablet, USP, the dose and frequency should be adjusted to suit an individual patient's needs. Rheumatoid arthritis: For relief of the signs and symptoms of rheumatoid arthritis, the usual recommended dose is 1200 mg (two 600-mg tablets) given orally once a day (see Individualization of dosage ). Osteoarthritis: For relief of the signs and symptoms of osteoarthritis, the usual recommended dose is 1200 mg (two 600-mg tablets) given orally once a day (see Individualization of dosage ). Juvenile rheumatoid arthritis: For the relief of the signs and symptoms of JRA in patients 6-16 years of age, the recommended dose given orally once per day should be based on body weight of the patient as given in Table 3 (see also Individualization of dosage ). Table 3 Body Weight Range (kg) Dose (mg) 22-31 600 32-54 900 ≥55 1200 (see CLINICAL PHARMACOLOGY: Special populations: Pediatric patients ) Individualization of dosage: As with other NSAIDs, the lowest dose should be sought for each patient. Therefore, after observing the response to initial therapy with oxaprozin tablet, USP, the dose and frequency should be adjusted to suit an individual patient's needs. In osteoarthritis and rheumatoid arthritis and juvenile rheumatoid arthritis, the dosage should be individualized to the lowest effective dose of oxaprozin tablet, USP to minimize adverse effects. The maximum recommended total daily dose of oxaprozin tablet, USP in adults is 1800 mg (26 mg/kg, whichever is lower) in divided doses. In children, doses greater than 1200 mg have not been studied. Patients of low body weight should initiate therapy with 600 mg once daily.Patients with severe renal impairment or on dialysis should also initiate therapy with 600 mg once daily. If there is insufficient relief of symptoms in such patients, the dose may be cautiously increased to 1200 mg, but only with close monitoring (see CLINICAL PHARMACOLOGY , Special populations ).
Excerpted — the section continues on the label. Read the full Dosage and Administration section on DailyMed →
Oxaprozin Side Effects
▾
The most common side effects are mostly stomach-related.
Common side effects
- Constipation
- Diarrhea
- Indigestion (dyspepsia)
- Nausea
- Rash
- Heartburn or abdominal pain
- Swelling (edema)
- Headache or dizziness
When to get medical help
- Get emergency help for chest pain, shortness of breath, weakness on one side of the body or slurred speech, which can be signs of a heart attack or stroke.
- Call your doctor right away for black or bloody stools, vomiting blood or severe stomach pain. Serious stomach or intestinal bleeding can happen without warning.
- Stop the medicine and get help at the first sign of a skin rash, blistering, swelling of the face or other allergic signs.
- Seek emergency help for signs of a severe allergic reaction (anaphylaxis).
- Call your doctor for signs of liver trouble such as nausea, unusual tiredness, itching, yellow skin or eyes, upper right belly tenderness or flu-like symptoms.
- Report fever with rash, swollen glands or facial swelling, which can be signs of a serious reaction called DRESS.
- Tell your doctor about new or worsening swelling, weight gain or high blood pressure.
Get help right away for signs of bleeding, a serious skin reaction, an allergic reaction, liver problems or heart attack or stroke symptoms. In children with juvenile rheumatoid arthritis, stomach symptoms and rashes on sun-exposed skin were reported.
Oxaprozin Warnings and Precautions
▾
- Heart attack and stroke: NSAIDs raise this risk, which may start early and grow with longer use.
- Stomach and intestinal bleeding, ulcers and perforation: These can occur without warning and can be fatal. Risk is higher with a past ulcer or bleeding, older age, smoking, alcohol, and blood thinners, steroids or SSRIs.
- Blood pressure and fluid: NSAIDs can raise blood pressure and cause swelling or worsen heart failure.
- Kidneys and liver: NSAIDs can cause kidney injury, higher potassium and liver injury.
- Allergic and skin reactions: Anaphylaxis, Stevens-Johnson syndrome, toxic epidermal necrolysis and DRESS can occur.
- Blood: Anemia can occur. Tell your doctor if you have signs of anemia.
Oxaprozin Interactions
▾
Oxaprozin can interact with several common medicines.
- Warfarin, SSRIs, SNRIs and corticosteroids: higher bleeding or ulcer risk.
- Aspirin and other NSAIDs: more stomach risk with little extra benefit.
- ACE inhibitors, ARBs, beta-blockers and diuretics: weaker blood pressure control and possible kidney strain.
- Digoxin and lithium: levels may rise.
- Methotrexate, cyclosporine and pemetrexed: greater risk of toxicity.
- Glyburide: blood sugar monitoring at the start.
Interactions listed in the FDA-approved label
From the Oxaprozin prescribing information (“Drug Interactions”): what the manufacturer studied or reported to the FDA.
- Anticoagulants (e.g., warfarin), antiplatelet drugs, SSRIs, SNRIs (drugs that interfere with hemostasis): Synergistic effect on bleeding; increased risk of serious bleeding compared to either drug alone. Monitor patients for signs of bleeding.
- Aspirin: No greater therapeutic effect than NSAID alone, and significantly increased incidence of GI adverse reactions. Concomitant use with analgesic doses of aspirin is not generally recommended; oxaprozin is not a substitute for low dose aspirin for cardiovascular protection.
- ACE inhibitors, angiotensin receptor blockers, beta-blockers: NSAIDs may diminish the antihypertensive effect; in elderly, volume-depleted or renally impaired patients, ACE inhibitors/ARBs may result in deterioration of renal function, including possible acute renal failure. Monitor blood pressure and renal function; ensure patients are adequately hydrated; assess renal function at start and periodically.
- Diuretics (loop e.g. furosemide, thiazide): NSAIDs reduced the natriuretic effect of loop and thiazide diuretics in some patients. Observe for signs of worsening renal function and assure diuretic efficacy including antihypertensive effects.
- Digoxin: Reported to increase serum concentration and prolong half-life of digoxin. Monitor serum digoxin levels.
- Lithium: NSAIDs produced elevations in plasma lithium levels and reductions in renal lithium clearance; mean minimum lithium concentration increased 15% and renal clearance decreased by approximately 20%. Monitor for signs of lithium toxicity.
- Methotrexate: May increase the risk for methotrexate toxicity (e.g., neutropenia, thrombocytopenia, renal dysfunction). Monitor patients for methotrexate toxicity.
- Cyclosporine: May increase cyclosporine's nephrotoxicity. Monitor for signs of worsening renal function.
- Other NSAIDs or salicylates (e.g., diflunisal, salsalate): Increases the risk of GI toxicity, with little or no increase in efficacy. Concomitant use is not recommended.
- Pemetrexed: May increase the risk of pemetrexed-associated myelosuppression, renal, and GI toxicity. In renal impairment with creatinine clearance 45 to 79 mL/min, monitor for myelosuppression, renal and GI toxicity; avoid short half-life NSAIDs for two days before, day of, and two days after pemetrexed; interrupt longer half-life NSAIDs for at least five days before, day of, and two days after.
Read the label’s full interactions text
7 DRUG INTERACTIONS See Table 2 for clinically significant drug interactions with oxaprozin [ see Clinical Pharmacology ( 12.3 ) ]. Table 2: Clinically Significant Drug Interactions with Oxaprozin Drugs That Interfere with Hemostasis Clinical Impact: Oxaprozin and anticoagulants such as warfarin have a synergistic effect on bleeding. The concomitant use of oxaprozin and anticoagulants have an increased risk of serious bleeding compared to the use of either drug alone. Serotonin release by platelets plays an important role in hemostasis. Case-control and cohort epidemiological studies showed that concomitant use of drugs that interfere with serotonin reuptake and an NSAID may potentiate the risk of bleeding more than an NSAID alone. Intervention: Monitor patients with concomitant use of oxaprozin tablets with anticoagulants (e.g., warfarin), antiplatelet drugs (e.g., aspirin), SSRIs, and SNRIs for signs of bleeding [ see Warnings and Precautions ( 5.12 ) ]. Aspirin Clinical Impact: Controlled clinical studies showed that the concomitant use of NSAIDs and analgesic doses of aspirin does not produce any greater therapeutic effect than the use of NSAIDs alone. In a clinical study, the concomitant use of an NSAID and aspirin was associated with a significantly increased incidence of GI adverse reactions as compared to use of the NSAID alone [ see Warnings and Precautions ( 5.2 ) ]. Intervention: Concomitant use of oxaprozin tablets and analgesic doses of aspirin is not generally recommended because of the increased risk of bleeding [ see Warnings and Precautions ( 5.12 ) ]. Oxaprozin tablets are not a substitute for low dose aspirin for cardiovascular protection. ACE Inhibitors, Angiotensin Receptor Blockers, and Beta-Blockers Clinical Impact: NSAIDs may diminish the antihypertensive effect of ACE inhibitors, ARBs, or beta-blockers (including propranolol).
Excerpted — the section continues on the label. Read the full Drug Interactions section on DailyMed →
Not a complete list. The label covers the interactions the manufacturer studied or reported, and our own interaction database does not cover every medicine either. Bring your full medication list, including vitamins and herbal products, to your pharmacist.
Before Taking Oxaprozin
▾
- Allergy to oxaprozin, or asthma, hives or allergic reactions after aspirin or other NSAIDs, means you should not take it.
- It must not be used around CABG surgery.
- It must not be used with active GI bleeding.
- Use extra caution with a past ulcer or GI bleeding, heart disease, high blood pressure, heart failure, kidney or liver disease, or asthma.
- Pregnancy: limit use between about 20 and 30 weeks and avoid at about 30 weeks and later.
- NSAIDs may reversibly affect fertility in women.
- Breastfeeding: use only if clearly needed, after discussing it with your doctor.
- Children under 6 have not been studied.
- Older adults face higher risks of serious GI events.
Oxaprozin Overdose
▾
Too much can cause lethargy, drowsiness, nausea, vomiting and upper stomach pain. GI bleeding can occur, and rarely high blood pressure, kidney failure, slowed breathing or coma. There is no specific antidote, and care is supportive. Call a poison control center (1-800-222-1222) or seek emergency help.
What Oxaprozin Does in the Body
▾
Oxaprozin has pain-relieving, anti-inflammatory and fever-reducing effects. It is a potent inhibitor of prostaglandin production. The amounts reached during treatment have shown effects in the body. It also penetrates into joint tissues in people with rheumatoid arthritis.
How Your Body Processes Oxaprozin
▾
Oxaprozin is about 95% absorbed after being taken by mouth, and peak levels occur in roughly 2 to 3 hours. It is highly bound to proteins in the blood. The liver breaks it down into mostly inactive metabolites, which leave through the urine and feces. The elimination half-life is about 40 to 55 hours for total drug, which supports once-daily use.
How to Store Oxaprozin
▾
Keep bottles tightly closed. Store at room temperature 20°C to 25°C (68°F to 77°F); excursions permitted between 15°C to 30°C (59°F to 86°F) . Dispense in a tight, light-resistant container with a child-resistant closure.
Written from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →
Supplements & Herbs That Interact With Oxaprozin
52 supplements and herbal products have documented interactions with Oxaprozin in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.
- Major · 5
- Moderate · 35
- Minor · 12
Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.
Nutrient Depletion Considerations
Oxaprozin has been associated with lower levels of 1 nutrient in the clinical literature. This does not mean a deficiency will occur — it means these may be worth discussing with your pharmacist or healthcare provider, especially with long-term use.
Educational information from a licensed clinical database (Natural Medicines) — not medical advice. Do not start or stop medications or supplements without professional guidance.
Oxaprozin: Pharmacist Answers to Common Questions
Quick, plain-English answers to the questions patients ask most about Oxaprozin — the kind of thing our pharmacy team would talk through with you at the counter.
What is oxaprozin for?
▾
How should I take it?
▾
What side effects are normal?
▾
When should I call my doctor or get emergency help?
▾
Can I take it with other pain relievers or my other medicines?
▾
Is it safe in pregnancy?
▾
Is Oxaprozin available over the counter?
▾
When was Oxaprozin first available?
▾
Who makes Oxaprozin?
▾
Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →
More About Oxaprozin on HelloPharmacist
Oxaprozin Forms and Strengths (How It Comes)
Oxaprozin is available in 2 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.
Need a version that does not list lactose, a gluten source, a dye or gelatin? Inactive ingredients differ by manufacturer: see Oxaprozin inactive ingredients by manufacturer.
Tablet
How this form is used
- Oxaprozin tablets are used to relieve the signs and symptoms of osteoarthritis, rheumatoid arthritis and juvenile rheumatoid arthritis.
- Oxaprozin tablets are taken by mouth, usually once a day.
- For juvenile rheumatoid arthritis, the Oxaprozin tablet amount is based on the child's body weight.
- Oxaprozin tablets: people with low body weight or severe kidney impairment or on dialysis start at a lower amount.
Capsule
How this form is used
- Coxanto capsules are used to relieve the signs and symptoms of osteoarthritis, rheumatoid arthritis and juvenile rheumatoid arthritis.
- Oxaprozin capsules are used for the same three conditions.
- Coxanto and Oxaprozin capsules are taken by mouth once a day.
- Coxanto and Oxaprozin capsules are not interchangeable with other oxaprozin strengths or formulations such as tablets.
- For juvenile rheumatoid arthritis, the Coxanto capsule amount is based on the child's body weight.
Oxaprozin on the U.S. Market: Products, Makers and Brands
How Oxaprozin appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.
8 companies list 10 Oxaprozin product records with the FDA, mostly as tablet, capsule; the earliest marketing or approval year on record is 1992. Brand names on the directory include Daypro, Coxanto; the rest are generics.
FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.
Also listed with the FDA, not a patient dose form: Powder (2) — bulk drug substance and unfinished product sold to compounders and other manufacturers to finish, and multi-item kits. These aren’t counted in the dose-form total above.
Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.
How Widely Oxaprozin Is Used (Medicaid Data)
A general measure of how commonly Oxaprozin is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.
Think of this as a proxy for how widely Oxaprozin is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.
How commonly is Oxaprozin prescribed? Of the 1,603 medications we measure, Oxaprozin ranks #1,092 by Medicaid prescriptions — more than 32% of them.
Utilization by Oxaprozin product
Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.
oxaprozin 600 MG Oral Tablet
Summed across the 3 of 92 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 312132
Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.
Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Oxaprozin, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 3 of 92 listed Oxaprozin NDCs with Medicaid activity.
Compare Oxaprozin Products
A representative set of FDA-listed product records for Oxaprozin — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)
| Strength | Route | Manufacturer / Labeler | Category ⓘ | Details |
|---|---|---|---|---|
| 💊Capsule | ||||
| 300 mg | Oral | SOLA Pharmaceuticals, LLC × 2 listings | NDA | View NDC → |
| 💊Tablet | ||||
| 600 mg | Oral | Amneal Pharmaceuticals NY LLC | ANDA | View NDC → |
| 600 mg | Oral | Bryant Ranch Prepack × 2 listings | ANDA | View NDC → |
| 600 mg | Oral | Chartwell RX, LLC. | ANDA | View NDC → |
| 600 mg | Oral | Direct_Rx | ANDA | View NDC → |
| 600 mg | Oral | Dr. Reddy's Laboratories Limited | ANDA | View NDC → |
| 600 mg | Oral | Proficient Rx LP | ANDA | View NDC → |
| 600 mg | Oral | St Mary's Medical Park Pharmacy | ANDA | View NDC → |
Showing 10 of 10 products — FDA National Drug Code Directory. See every product, package size and price: browse all 10 Oxaprozin NDCs →
Oxaprozin Side Effects Reported to the FDA (FAERS)
After a medicine reaches the market, patients, doctors and drugmakers can send the FDA reports of problems they think may be linked to it. Here’s what’s been reported for Oxaprozin — a signal of what to watch for, not proof the drug caused it.
Source: openFDA, from the FDA Adverse Event Reporting System (FAERS). These are voluntary reports — they don’t prove the drug caused the effect, and counts reflect how often something was reported, not how often it actually happens. Reports also often name the very problem the medicine is taken for — a common reason to file one is that the drug didn’t help — so for a pain reliever you may see “pain” high on the list; that points to why the report was filed, not to the drug causing the symptom. This counts every report that lists Oxaprozin in any role, so the total runs higher than the FDA’s official dashboard, which counts only cases where the drug is the suspect. For the authoritative figures, see the FDA FAERS Public Dashboard. Always talk to your pharmacist or doctor.
Oxaprozin FDA Approval History
How Oxaprozin went from FDA review to the pharmacy shelf — the key milestones in its regulatory journey.
Source: Drugs@FDA.
Oxaprozin Recall History
A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.
The FDA’s enforcement reports list no Oxaprozin recalls since July 2021.
✅No Oxaprozin recalls on record since July 2021Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Oct 8, 2026.
RxNorm Concept Web — From Ingredient to Every Form and Strength
This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.
RxCUI 32613 2 dose forms · 2 strengths
Look up RxCUI 32613 in the RxCUI Atlas →
RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.
Oxaprozin Supply and Shortage Status
Whether Oxaprozin is in short supply in the U.S. right now, plus any shortage history the FDA has on record. A shortage usually reflects a manufacturing or demand issue — not a safety problem with the drug.
Source: openFDA, from the FDA Drug Shortages database.
💵 What Oxaprozin Costs Pharmacies (NADAC Benchmark)
The national average invoice price pharmacies pay for the drug itself, from CMS's NADAC survey (data as of Sep 30, 2026). This is a supply-cost benchmark — not a retail price and not what you'd pay at the counter.
| Form | Strength | Pharmacy acquisition benchmark | |
|---|---|---|---|
| Tablet · Oral | 600 mg | $0.475 per tablet | NDC details & price history |
| Tablet, Film Coated · Oral | 600 mg | $0.475 per tablet | NDC details & price history |
Source: CMS National Average Drug Acquisition Cost (NADAC), a survey of retail pharmacy invoice prices. Benchmarks shown are the range across package sizes of a representative product for each form and strength — other manufacturers' products may differ.
Oxaprozin Brand Names
Oxaprozin is sold under 2 brand names in the FDA directory — Daypro, Coxanto. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.
Who Makes Oxaprozin: Manufacturers and Labelers
8 companies list Oxaprozin products with the FDA. By number of product records, the largest are Bryant Ranch Prepack, SOLA Pharmaceuticals, LLC, Amneal Pharmaceuticals NY LLC. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.
Oxaprozin Drug Class (RxNorm)
Oxaprozin belongs to the Nonsteroidal Anti-inflammatory Drug class.
Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.
Sources for This Oxaprozin Page
Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.
How this page is built
HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. SOLA Pharmaceuticals, LLC is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →