Drug & supplement interaction

Collagen Type I (native) + Verapamil

Verapamil brand names: Isoptin SR, Verelan, Isoptin, Calan SR, Verelan SR, and others.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Collagen Type I (native) and Verapamil in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Collagen Type I (native) and Verapamil

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Verapamil and Collagen Type I (native) in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Collagen Type I (native) at all — not against Verapamil, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Collagen Type I (native) safety at a glance

Collagen Type I (n... overall Use caution Generally well tolerated for most adults, but quality and source vary widely between products.
Pregnancy Avoid Safety has not been established, so it is best to avoid unless your doctor approves.
Breastfeeding Avoid Not enough safety data exists, so avoid use while breastfeeding unless advised otherwise.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Verapamil and Collagen Type I (native)? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Collagen Type I (native) and Verapamil May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Stomach upset Additional detail

    Collagen Type I (native)

    “Orally, dyspepsia occurred in one patient in one clinical trial.”

    Collagen Type I (native) · Natural Medicines adverse-effect record, reported in dyspepsia.

    1 source cited
    1. 101769. Stancík R, Zvarka J, Hlavác M, Kubinec V, Rovenský J. Collagen type I in the treatment of painful osteoarthritis of the knee. Reumatologia. 2012;50(5):390-6. DOI

    Verapamil

    Listed in the ADVERSE REACTIONS section of the FDA label for Verapamil. Read the label on DailyMed ›

Effects for Verapamil come from the ADVERSE REACTIONS section of its FDA label; effects for Collagen Type I (native) come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

From our Q&A

Questions About Collagen Type I (native) or Verapamil

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Collagen Type I (native) or Verapamil, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Verapamil

This page covers Collagen Type I (native) only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Verapamil page lists 295 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Beer (major) and Coleus (major).

By severity: 10 major · 245 moderate · 40 minor.

From our pharmacist’s overview on the Verapamil page

“This is one of the longer interaction lists we publish, and with verapamil (Calan, Verelan) it warrants genuine care, starting with the ten major-rated entries. Verapamil lowers blood pressure and slows the heart, so most of the 295 ingredients on file either push that effect further than intended or change how much of the drug reaches…”

Reviewed by 2 · Jul 18, 2026

Open the Verapamil interaction page

How much people look this up

Where Collagen Type I (native) and Verapamil Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Collagen Type I (native)
Steady interest

#1,301 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Verapamil
Top 25%

#643 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Collagen Type I (native) reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Collagen Type I (native) and Verapamil records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Collagen Type I (native)

What is Collagen Type I (native)?

  • Skin health and wrinkles
  • Joint comfort and arthritis
  • Bone strength
  • Hair and nail support
  • Wound and tissue repair

Type I collagen is the most abundant protein in human skin, bones, and tendons, and it is sold as a supplement to support skin, joints, and bones. 'Native' (undenatured) Type I collagen keeps its natural triple-helix structure rather than being broken down into peptides. Early research is promising for skin and joints, but evidence is still limited, and most products are generally well tolerated.

Skin, bones, tendons, scales, and connective tissue of cows, pigs, fish, or chicken · Powders, capsules, drinks, and undenatured (native) collagen tablets

An interaction check asks whether these two react with each other — it does not ask whether Collagen Type I (native) is a good idea for someone in your situation. Here is what our Collagen Type I (native) record says about it on its own.

Collagen Type I (native): dosing

There is no official standardized dose for native Type I collagen, and the right amount depends on the specific product. Doses used in studies vary widely depending on the form (powder versus tablet) and whether the collagen is native or hydrolyzed.The safest approach is to follow the directions on the product label and not exceed them.

From our Collagen Type I (native) monograph — the full record covers uses, side effects and every documented interaction.

Read the full Collagen Type I (native) monograph & all interactions
Medication

About Verapamil

What Is Verapamil Used For?

Brand names: Isoptin SR, Verelan, Isoptin, Calan SR, Verelan SR, Calan, Covera HS, Verap, Veramil

Verapamil tablets and film-coated tablets are used to treat angina — including vasospastic (Prinzmetal's) angina, unstable angina, and chronic stable angina — as well as certain abnormal heart rhythms (arrhythmias) and high blood pressure (essential hypertension). For arrhythmias, regular-release tablets are used alongside digoxin to control heart rate in atrial flutter or atrial fibrillation, and to help prevent episodes of paroxysmal supraventricular tachycardia (SVT), a type of rapid heartbeat.

Extended-release and sustained-release oral forms (tablets and capsules) are indicated specifically for high blood pressure. Verapamil hydrochloride injection is used in hospital settings for rapid conversion of SVT to normal rhythm and for temporary control of fast heart rates in atrial flutter or atrial fibrillation.

Most-Reported Side Effects for Verapamil

From FAERS, the FDA’s public side-effect reporting system (4,297 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Dyspnea 352 reports
Nausea 351 reports
Dizziness 295 reports
Hypotension 293 reports
Fatigue 275 reports
See full Verapamil drug information
Keep checking

Other Drugs & Collagen Type I (native)

Browse every other medication we’ve checked against Collagen Type I (native) — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Collagen Type I (native) against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Collagen Type I (native) list.

See the full Collagen Type I (native) interactions page
See every supplement checked against Verapamil, ranked by severity
Evidence & sources

Collagen Type I (native) References

The 1 references that drive our Collagen Type I (native) monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Stancík R, Zvarka J, Hlavác M, Kubinec V, Rovenský J. Collagen type I in the treatment of painful osteoarthritis of the knee. Reumatologia. 2012;50(5):390-6. DOI

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Collagen Type I (native) and Verapamil Together: Common Questions

Is it safe to take Collagen Type I (native) with Verapamil?
We do not list a known interaction between Collagen Type I (native) and Verapamil. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Collagen Type I (native) and Verapamil have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Verapamil interact with any supplements?
Yes. Verapamil has documented interactions with 295 supplements in our database — Collagen Type I (native) is not one of them. The Verapamil interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Collagen Type I (native) monograph Uses, safety profile, and every drug interaction in one place Verapamil drug information The full plain-English guide to this medication Verapamil supplement interactions Every supplement checked against Verapamil, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Verapamil and Collagen Type I (native)?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.