Drug & supplement interaction

Collard + Carmustine

Carmustine brand names: Gliadel, BiCNU, Gliadel Wafer.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Collard and Carmustine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Collard and Carmustine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Carmustine and Collard in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Collard safety at a glance

Collard overall Generally safe Collard is widely eaten as a food and is generally safe for most people.
Pregnancy Generally safe Normal food amounts are considered safe and nutritious during pregnancy.
Breastfeeding Generally safe Eating collard as a food is generally considered safe while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Carmustine and Collard? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Carmustine

Interactions in our licensed database are recorded against drug classes, not just single drug names. Carmustine is filed under 2 classifications — alkylating agents, oral drugs. Collard has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Carmustine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Collard Does Interact With Other Medications

Collard has 86 moderate known drug interactions in our database — Carmustine isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Collard

Covers the 2,830 medications we’ve checked against Collard. Pick one to open its full report.

What to actually watch for

What Carmustine’s Own FDA Label Lists

This is not an interaction — none of it involves Collard. These are the most notable effects listed in the ADVERSE REACTIONS section of Carmustine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 7 of them are worth acting on rather than waiting out — marked below.

  • Blood clots Worth acting on
  • Seizures Worth acting on
  • Chest pain Worth acting on
  • Low mood Worth acting on
  • Raised blood pressure Worth acting on
  • Bleeding or bruising Worth acting on
  • A higher chance of infection Worth acting on
  • Back pain
  • Fever
  • Constipation

Showing the 10 most notable of 15 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Carmustine. Read the label on DailyMed › Collard’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Collard side to compare — that is a limit of the record, not a statement that Collard has no side effects.

Everything else you take

See Every Supplement That Interacts With Carmustine

This page covers Collard only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Carmustine page lists 24 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Acerola (moderate), Alpha-lipoic Acid (moderate), Coenzyme Q10 (moderate) and Coffee Charcoal (moderate).

By severity: 1 major · 14 moderate · 9 minor.

From our pharmacist’s overview on the Carmustine page

“Activated charcoal is the entry to understand first. It holds the only major rating among the 24 ingredients on file for carmustine, and because it can trap drugs that recirculate through the gut, it may lower carmustine levels even when the chemotherapy arrives by IV or as an implanted Gliadel wafer.”

Reviewed by 2 · Jul 18, 2026

Open the Carmustine interaction page

One more smart check

Taking Collard as Part of a Dietary Supplement Product? Check It for Interactions

We hold 379 real supplement products containing Collard, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Collard. Even though Collard itself has no known interaction with Carmustine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Collard and Carmustine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Collard
Top half

#471 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Carmustine
Top half

#960 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Collard reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Collard and Carmustine records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Collard

What is Collard?

  • General nutrition and vitamin source
  • Bone health
  • Heart health support
  • Digestive fiber
  • Antioxidant intake

Collard is a leafy green vegetable in the cabbage family that is rich in vitamins, minerals, and fiber, and is best thought of as a nutritious food rather than a medicine. Eating it as part of a balanced diet is healthy for most people, but there is little high-quality research on collard as a concentrated supplement. If you take blood thinners or have kidney concerns, talk with your pharmacist or doctor because of its vitamin K and oxalate content.

Brassica oleracea var. viridis · Brassicaceae · Leaves · Fresh or cooked leaves, frozen greens; occasionally powders or capsules

An interaction check asks whether these two react with each other — it does not ask whether Collard is a good idea for someone in your situation. Here is what our Collard record says about it on its own.

Collard: dosing

There is no established medicinal dose for collard. As a food, it can be enjoyed in normal serving sizes as part of a varied diet, just like other vegetables.If you choose a collard powder or capsule, there is no standardized dose, so follow the directions on the product label.

From our Collard monograph — the full record covers uses, side effects and every documented interaction.

Read the full Collard monograph & all interactions
Medication

About Carmustine

What Is Carmustine Used For?

Brand names: Gliadel, BiCNU, Gliadel Wafer

Carmustine injection is used as palliative therapy — either alone or combined with other chemotherapy drugs — for several brain tumors, including glioblastoma, brainstem glioma, medulloblastoma, astrocytoma, ependymoma, and metastatic brain tumors. It is also used for multiple myeloma (in combination with prednisone), and for relapsed or refractory Hodgkin's lymphoma and Non-Hodgkin's lymphomas (in combination with other approved drugs).

Gliadel — a dissolving wafer form of carmustine placed directly into the brain during surgery — is specifically indicated for newly diagnosed high-grade glioma (as an addition to surgery and radiation) and for recurrent glioblastoma (as an addition to surgery).

Most-Reported Side Effects for Carmustine

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Febrile neutropenia 391 reports
Myelodysplastic syndrome 296 reports
Disease progression 292 reports
Thrombocytopenia 250 reports
Fever 238 reports
See full Carmustine drug information
Keep checking

Other Drugs & Collard

Browse every other medication we’ve checked against Collard — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Collard page.

No interaction 2,743 drugs checked — show the list
Evidence & sources

Collard References

The 4 references that drive our Collard monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Zhao H, Lin J, Grossman HB, et al. Dietary isothiocyanates, GSTM1, GSTT1, NAT2 polymorphisms and bladder cancer risk. Int J Cancer 2007;120:2208-13.
  2. Cohen, J. H., Kristal, A. R., and Stanford, J. L. Fruit and vegetable intakes and prostate cancer risk. J Natl.Cancer Inst. 1-5-2000;92(1):61-68. PubMed
  3. Gaudet MM, Britton JA, Kabat GC, et al. Fruits, vegetables, and micronutrients in relation to breast cancer modified by menopause and hormone receptor status. Cancer Epidemiol Biomarkers Prev 2004;13(9):1485-94. DOI
  4. Amssayef A, Eddouks M. Antihyperglycemic Effect of the Moroccan Collard Green (Brassica oleracea var. viridis) in Streptozotocin-Induced Diabetic Rats. Endocr Metab Immune Disord Drug Targets 2020. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Collard and Carmustine Together: Common Questions

Is it safe to take Collard with Carmustine?
We do not list a known interaction between Collard and Carmustine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Collard and Carmustine combination checked?
Interactions in our licensed database are recorded against drug classes. Carmustine is filed under 2 classifications, and Collard has documented interactions with 1 drug class — none of Carmustine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Collard interact with any other medications?
Yes. Collard has 86 documented drug interactions in our database — Carmustine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Carmustine interact with any supplements?
Yes. Carmustine has documented interactions with 24 supplements in our database — Collard is not one of them. The Carmustine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Carmustine and Collard?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.