Drug & supplement interaction

Common Stonecrop + Hydrogen Peroxide

Hydrogen Peroxide brand name: Eskata.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated July 2026 · Pair last verified Sep 20, 2026

The bottom line No known interaction

We found no known interaction between Common Stonecrop and Hydrogen Peroxide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Common Stonecrop and Hydrogen Peroxide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Hydrogen Peroxide and Common Stonecrop in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Common Stonecrop at all — not against Hydrogen Peroxide, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Common Stonecrop safety at a glance

Common Stonecrop overall Use caution Limited safety data exist, and internal use can cause irritation, vomiting, and diarrhea.

Pregnancy Avoid There is not enough safety information, so avoid use during pregnancy.

Breastfeeding Avoid Safety while breastfeeding is unknown, so it is best to avoid it.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Hydrogen Peroxide and Common Stonecrop? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

What to actually watch for

What Common Stonecrop Itself Has Been Linked To

This is not an interaction — nothing below involves Hydrogen Peroxide. It is the side-effect record for Common Stonecrop on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Common Stonecrop, this list is the first place to look.

Diarrhea / Vomiting Additional detail
“Orally, common stonecrop can cause vomiting and diarrhea when consumed in very large amounts (18).”

Common Stonecrop · Natural Medicines adverse-effect record, reported in diarrhea.
1 source cited

18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Everything above comes from the Natural Medicines adverse-effect record for Common Stonecrop — expand a row for the licensed statement it rests on. We haven’t matched Hydrogen Peroxide to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Hydrogen Peroxide.

Everything else you take

See Every Supplement That Interacts With Hydrogen Peroxide

This page covers Common Stonecrop only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Hydrogen Peroxide page lists 3 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Dimethylsulfoxide (dmso) (moderate), Turpentine Oil (moderate) and Alchemilla (minor).

By severity: 2 moderate · 1 minor.

From our pharmacist’s overview on the Hydrogen Peroxide page

“DMSO is the one to know about first. Applied near skin treated with hydrogen peroxide (Eskata, the prescription form used in clinics to clear seborrheic keratoses), DMSO can carry topical drugs deeper into the skin than intended, potentially strengthening both the effect and the irritation.”

Reviewed by 2 · Jul 18, 2026

Open the Hydrogen Peroxide interaction page

How much people look this up

Where Common Stonecrop and Hydrogen Peroxide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Common Stonecrop

Steady interest

#1,246 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Hydrogen Peroxide

Steady interest

#2,283 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Common Stonecrop reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Common Stonecrop and Hydrogen Peroxide records this page draws on were last updated July 10, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Common Stonecrop

What is Common Stonecrop?

Wounds and skin irritation
Eczema and other skin conditions
Constipation (laxative use)
Urinary and bladder complaints
High blood pressure (folk use)

Common Stonecrop (Sedum acre) is a small succulent with a long history in European folk medicine, mostly applied to the skin or used as a laxative. There is very little modern scientific evidence to support any of its uses, and the plant can be irritating and may cause vomiting or diarrhea when swallowed, so it should be used with caution and ideally avoided internally.

Sedum acre · Crassulaceae · Above-ground parts (leaves, stems, and flowering tops), used fresh or dried · Fresh plant, dried herb, topical preparations, and rarely teas or tinctures

An interaction check asks whether these two react with each other — it does not ask whether Common Stonecrop is a good idea for someone in your situation. Here is what our Common Stonecrop record says about it on its own.

Common Stonecrop: dosing

There is no established or standardized dose for Common Stonecrop. Because it has not been studied in proper clinical trials, safe and effective amounts are simply not known.If you choose to use a commercial product, follow the directions on the label and do not exceed them.

From our Common Stonecrop monograph — the full record covers uses, side effects and every documented interaction.

Read the full Common Stonecrop monograph & all interactions

Medication

About Hydrogen Peroxide

Most-Reported Side Effects for Hydrogen Peroxide

From FAERS, the FDA’s public side-effect reporting system (326 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Nausea 24 reports

Fatigue 23 reports

Pruritus 17 reports

Vomiting 17 reports

Headache 16 reports

Keep checking

Other Drugs & Common Stonecrop

Browse every other medication we’ve checked against Common Stonecrop — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

0Moderate

0Minor

2,829No known interaction

2,829 No interaction

No interaction 2,829 drugs checked — show the list

We also checked Common Stonecrop against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Common Stonecrop list.

See the full Common Stonecrop interactions page

See every supplement checked against Hydrogen Peroxide, ranked by severity

Evidence & sources

Common Stonecrop References

The 1 references that drive our Common Stonecrop monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Common Stonecrop and Hydrogen Peroxide Together: Common Questions

Is it safe to take Common Stonecrop with Hydrogen Peroxide?

We do not list a known interaction between Common Stonecrop and Hydrogen Peroxide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Does Hydrogen Peroxide interact with any supplements?

Yes. Hydrogen Peroxide has documented interactions with 3 supplements in our database — Common Stonecrop is not one of them. The Hydrogen Peroxide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Common Stonecrop monograph Uses, safety profile, and every drug interaction in one place Hydrogen Peroxide supplement interactions Every supplement checked against Hydrogen Peroxide, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Hydrogen Peroxide and Common Stonecrop?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.