Drug & supplement interaction

Condurango + Procarbazine

Procarbazine brand name: Matulane.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Condurango and Procarbazine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Condurango and Procarbazine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Procarbazine and Condurango in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Condurango at all — not against Procarbazine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Condurango safety at a glance

Condurango overall Use caution Little modern safety data exists, so use cautiously and at low amounts.
Pregnancy Avoid Safety is unknown, so it is best avoided during pregnancy.
Breastfeeding Avoid No reliable safety data exists, so avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Procarbazine and Condurango? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Procarbazine’s Own FDA Label Lists

This is not an interaction — none of it involves Condurango. These are the most notable effects listed in the ADVERSE REACTIONS section of Procarbazine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Hearing loss Worth acting on
  • Trouble swallowing Worth acting on
  • Unsteadiness Worth acting on
  • Hallucinations Worth acting on
  • Yellowing of the skin or eyes Worth acting on
  • Fainting Worth acting on
  • Confusion Worth acting on
  • Seizures Worth acting on
  • Low mood Worth acting on
  • Anemia Worth acting on

Showing the 10 most notable of 46 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Procarbazine. Read the label on DailyMed › Condurango’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Condurango side to compare — that is a limit of the record, not a statement that Condurango has no side effects.

Overlapping uses

What Procarbazine Is Prescribed For, and What Condurango Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Procarbazine is a prescription medicine with approved uses on its FDA label. Condurango is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Procarbazine is prescribed for: Matulane (procarbazine) is used to treat Stage III and IV Hodgkin's disease — advanced forms of a cancer that affects the lymphatic system. It is not used alone; it is always given as part of a combination chemotherapy regimen. Matulane is a key component of the MOPP regimen, which combines nitrogen mustard, vincristine, procarbazine, and prednisone.

Condurango has been studied for:

  • Cancer studied, not established Condurango has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Condurango for cancer

    Although there has been interest in using oral condurango for cancer, there is insufficient relable information about the clinical effects of condurango for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Procarbazine on your own; if you are taking Condurango for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Procarbazine

This page covers Condurango only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Procarbazine page lists 24 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Acerola (moderate), Alpha-lipoic Acid (moderate), Coenzyme Q10 (moderate) and Coffee Charcoal (moderate).

By severity: 1 major · 14 moderate · 9 minor.

From our pharmacist’s overview on the Procarbazine page

“Procarbazine (Matulane) is chemotherapy, taken by mouth for Hodgkin lymphoma, and that raises the stakes of every entry on this page. Anything that keeps a full dose from reaching the tumor deserves serious attention, and the one interaction rated major, activated charcoal, does exactly that by binding the drug in the gut.”

Reviewed by 2 · Jul 18, 2026

Open the Procarbazine interaction page

One more smart check

Taking Condurango as Part of a Dietary Supplement Product? Check It for Interactions

We hold 37 real supplement products containing Condurango, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Condurango. Even though Condurango itself has no known interaction with Procarbazine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Condurango and Procarbazine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Condurango
Top half

#609 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Procarbazine
Steady interest

#2,375 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Condurango is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Condurango reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Condurango and Procarbazine records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Condurango

What is Condurango?

  • Digestive upset
  • Loss of appetite
  • Stimulating gastric secretion
  • Indigestion and bloating
  • Traditional tonic

Condurango is the bark of a South American vine traditionally used as a bitter to stimulate appetite and ease digestive complaints. Modern scientific evidence supporting any of these uses is very limited, and its safety has not been well studied, so use caution and talk with a pharmacist or doctor before trying it.

Marsdenia condurango · Apocynaceae · Dried bark · Tincture, fluid extract, tea (decoction), homeopathic preparations

An interaction check asks whether these two react with each other — it does not ask whether Condurango is a good idea for someone in your situation. Here is what our Condurango record says about it on its own.

Condurango: dosing

There is no well-established or standardized dose of condurango. Traditional preparations included tinctures, fluid extracts, and bark teas, but the amounts vary widely between products.If you choose to use a condurango product, follow the directions on the label and do not exceed them.

From our Condurango monograph — the full record covers uses, side effects and every documented interaction.

Read the full Condurango monograph & all interactions
Medication

About Procarbazine

What Is Procarbazine Used For?

Brand name: Matulane

Matulane (procarbazine) is used to treat Stage III and IV Hodgkin's disease — advanced forms of a cancer that affects the lymphatic system. It is not used alone; it is always given as part of a combination chemotherapy regimen.

Matulane is a key component of the MOPP regimen, which combines nitrogen mustard, vincristine, procarbazine, and prednisone.

See full Procarbazine drug information
Keep checking

Other Drugs & Condurango

Browse every other medication we’ve checked against Condurango — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Condurango against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Condurango list.

See the full Condurango interactions page
See every supplement checked against Procarbazine, ranked by severity
Evidence & sources

Condurango References

The 1 sources that drive our Condurango monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Condurango is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Herbs at a Glance — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Condurango and Procarbazine Together: Common Questions

Is it safe to take Condurango with Procarbazine?
We do not list a known interaction between Condurango and Procarbazine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Condurango and Procarbazine used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Condurango in each. That is a conversation for your prescriber, especially if Procarbazine is being adjusted to a target.
Does Procarbazine interact with any supplements?
Yes. Procarbazine has documented interactions with 24 supplements in our database — Condurango is not one of them. The Procarbazine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Condurango monograph Uses, safety profile, and every drug interaction in one place Procarbazine drug information The full plain-English guide to this medication Procarbazine supplement interactions Every supplement checked against Procarbazine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Procarbazine and Condurango?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.