Drug & supplement interaction

Corn Poppy + Mexiletine

Mexiletine brand name: Mexitil.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Corn Poppy and Mexiletine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Mexiletine states a food rule worth keeping to.

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Interaction report

Corn Poppy and Mexiletine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Mexiletine and Corn Poppy in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Corn Poppy safety at a glance

Corn Poppy overall Use caution Generally low in strong alkaloids, but human safety data are limited and it should be used cautiously.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid Not enough safety information, so it is best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Mexiletine and Corn Poppy? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Mexiletine

Interactions in our licensed database are recorded against drug classes, not just single drug names. Mexiletine is filed under 7 classifications — including cytochrome p450 1a2 (cyp1a2) inhibitors, cytochrome p450 1a2 (cyp1a2) substrates, cytochrome p450 1a2 (cyp1a2) substrates. Corn Poppy has documented interactions with 1 drug class — the most serious being cns depressants (moderate) — and none of Mexiletine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Corn Poppy Does Interact With Other Medications

Corn Poppy has 248 moderate known drug interactions in our database — Mexiletine isn’t one of them. If you take anything else, check it against the full list below.

Moderate 248 No known interaction 2,582 (incl. Mexiletine)
Taking anything else?

Check Another of Your Medications Against Corn Poppy

Covers the 2,830 medications we’ve checked against Corn Poppy. Pick one to open its full report.

What to actually watch for

What Corn Poppy Itself Has Been Linked To

This is not an interaction — nothing below involves Mexiletine. It is the side-effect record for Corn Poppy on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Corn Poppy, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Hives Worth acting on Additional detail

    “Topically, corn poppy flowers may cause allergic contact urticaria.”

    Corn Poppy · Natural Medicines adverse-effect record, reported in urticaria.

    1 source cited
    1. 46284. Gamboa, P. M., Jauregui, I., Urrutia, I., Gonzalez, G., Barturen, P., and Antepara, I. Allergic contact urticaria from poppy flowers (Papaver rhoeas). Contact Dermatitis 1997;37(3):140-141.

Everything above comes from the Natural Medicines adverse-effect record for Corn Poppy — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Mexiletine’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Mexiletine column appears here.

How to take them

Some Mexiletine Products Have a Food Rule — Corn Poppy Should Not Break It

At least one FDA label for a product containing Mexiletine says to take it with food. If you take Corn Poppy on an empty stomach out of habit, keep them separate — and take Mexiletine with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Mexiletine products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

Administration with food or antacid is recommended.

From the Dosage and Administration section of the FDA label we read for Mexiletine — where that label names a specific product, the instruction is that product's. See the Mexiletine drug page ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Mexiletine

This page covers Corn Poppy only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Mexiletine page lists 152 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), 1,3-dmaa (moderate), Acacia Rigidula (moderate), Active Hexose Correlated Compound (ahcc) (moderate) and Adrafinil (moderate).

By severity: 1 major · 107 moderate · 44 minor.

From our pharmacist’s overview on the Mexiletine page

“Mexiletine (Mexitil) steadies the heart's rhythm, and its benefit depends on holding a fairly precise blood level, so the 152 supplements on this list deserve real attention rather than a shrug. Only one entry, activated charcoal, is rated major, because it can soak up the drug in the gut and cut how much actually reaches your bloodstr…”

Reviewed by 2 · Jul 18, 2026

Open the Mexiletine interaction page

One more smart check

Taking Corn Poppy as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing Corn Poppy, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Corn Poppy. Even though Corn Poppy itself has no known interaction with Mexiletine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Corn Poppy and Mexiletine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Corn Poppy
Top half

#512 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Mexiletine
Top 25%

#671 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Corn Poppy reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Corn Poppy and Mexiletine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Corn Poppy

What is Corn Poppy?

Corn Poppy
  • Cough and sore throat
  • Sleep and restlessness
  • Mild pain
  • Anxiety and nervousness
  • Digestive complaints

Corn poppy is a red-flowered plant traditionally used in teas and syrups for cough, sleep, and mild pain. Solid human research is very limited, so its benefits are not well proven, and unlike its relative the opium poppy, it contains only small amounts of weak alkaloids. Talk to a pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Papaver rhoeas · Papaveraceae · Flowers (petals) and leaves · Tea, syrup, dried petals, tincture, capsules

An interaction check asks whether these two react with each other — it does not ask whether Corn Poppy is a good idea for someone in your situation. Here is what our Corn Poppy record says about it on its own.

Corn Poppy: dosing

There is no well-established or standardized dose for corn poppy. Traditional use generally involves small amounts of the dried petals made into a tea or syrup.Because products vary widely in strength, follow the directions on the product label and do not exceed the suggested amount. Avoid giving it to infants or young children.

From our Corn Poppy monograph — the full record covers uses, side effects and every documented interaction.

Read the full Corn Poppy monograph & all interactions
Medication

About Mexiletine

What Is Mexiletine Used For?

Brand name: Mexitil

Mexiletine Hydrochloride capsules are indicated for the treatment of documented, life-threatening ventricular arrhythmias — for example, sustained ventricular tachycardia (a dangerously fast heart rhythm originating in the lower chambers). Because mexiletine itself can trigger arrhythmias, it is not recommended for minor or symptom-free irregular heartbeats.

Treatment is started in a hospital setting so heart rhythm can be monitored closely. Antiarrhythmic drugs, including mexiletine, have not been shown to improve overall survival in patients with ventricular arrhythmias.

See full Mexiletine drug information
Keep checking

Other Drugs & Corn Poppy

Browse every other medication we’ve checked against Corn Poppy — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
248Moderate
0Minor
2,581No known interaction
248 Moderate 2,581 No interaction
Moderate

248 interactions

Showing 60 of 248 moderate interactions — see all 248 on the Corn Poppy page.

No interaction 2,581 drugs checked — show the list

We also checked Corn Poppy against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,581 medications checked with no known interaction — see the full Corn Poppy list.

See the full Corn Poppy interactions page
See every supplement checked against Mexiletine, ranked by severity
Evidence & sources

Corn Poppy References

The 2 references that drive our Corn Poppy monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Soulimani, R., Younos, C., Jarmouni-Idrissi, S., Bousta, D., Khalouki, F., and Laila, A. Behavioral and pharmaco-toxicological study of Papaver rhoeas L. in mice. J Ethnopharmacol 3-3-2001;74(3):265-274. PubMed
  2. Gamboa, P. M., Jauregui, I., Urrutia, I., Gonzalez, G., Barturen, P., and Antepara, I. Allergic contact urticaria from poppy flowers (Papaver rhoeas). Contact Dermatitis 1997;37(3):140-141.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Corn Poppy and Mexiletine Together: Common Questions

Is it safe to take Corn Poppy with Mexiletine?
We do not list a known interaction between Corn Poppy and Mexiletine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Corn Poppy and Mexiletine at the same time of day?
At least one FDA label for a product containing Mexiletine says to take it with food. If you take Corn Poppy on an empty stomach out of habit, keep them separate and take Mexiletine with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Mexiletine products can differ — so check the directions on your own box. This is about absorption, not an interaction.
How was the Corn Poppy and Mexiletine combination checked?
Interactions in our licensed database are recorded against drug classes. Mexiletine is filed under 7 classifications, and Corn Poppy has documented interactions with 1 drug class — none of Mexiletine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Corn Poppy interact with any other medications?
Yes. Corn Poppy has 248 documented drug interactions in our database — Mexiletine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Mexiletine interact with any supplements?
Yes. Mexiletine has documented interactions with 152 supplements in our database — Corn Poppy is not one of them. The Mexiletine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Corn Poppy monograph Uses, safety profile, and every drug interaction in one place Mexiletine drug information The full plain-English guide to this medication Mexiletine supplement interactions Every supplement checked against Mexiletine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Mexiletine and Corn Poppy?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.