Drug & supplement interaction

Cumin + Avatrombopag Maleate

Avatrombopag Maleate brand name: Doptelet.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Cumin and Avatrombopag Maleate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Avatrombopag Maleate states a food rule worth keeping to.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Cumin and Avatrombopag Maleate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Avatrombopag Maleate and Cumin in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Cumin safety at a glance

Cumin overall Generally safe Cumin used as a spice in food is generally safe for most people.
Pregnancy Use caution Food amounts are likely fine, but avoid medicinal or supplement doses due to limited safety data.
Breastfeeding Use caution Food amounts are likely fine, but there is not enough information on larger supplement doses.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Avatrombopag Maleate and Cumin? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Avatrombopag Maleate

Interactions in our licensed database are recorded against drug classes, not just single drug names. Avatrombopag Maleate is filed under 2 classifications — p-glycoprotein substrates, oral drugs. Cumin has documented interactions with 3 drug classes — the most serious being anticoagulant/antiplatelet drugs (moderate), antidiabetes drugs (moderate) and rifampin (rifadin) (moderate) — and none of Avatrombopag Maleate’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Cumin Does Interact With Other Medications

Cumin has 211 moderate known drug interactions in our database — Avatrombopag Maleate isn’t one of them. If you take anything else, check it against the full list below.

Moderate 211 No known interaction 2,619 (incl. Avatrombopag Maleate)
Taking anything else?

Check Another of Your Medications Against Cumin

Covers the 2,830 medications we’ve checked against Cumin. Pick one to open its full report.

What to actually watch for

What Cumin Itself Has Been Linked To

This is not an interaction — nothing below involves Avatrombopag Maleate. It is the side-effect record for Cumin on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Cumin, this list is the first place to look. 2 entries are worth acting on rather than waiting out — marked below.

  • A severe allergic reaction Worth acting on Additional detail

    “Orally, cumin may cause allergic reactions, including anaphylaxis, in sensitive individuals. One case report of anaphylaxis associated with cumin consumption has been reported.

    Topically, cumin may cause allergic contact dermatitis in sensitive individuals.”

    Cumin · Natural Medicines adverse-effect record, reported in dermatitis.

    3 sources cited
    1. 46905. Boxer, M., Roberts, M., and Grammer, L. Cumin anaphylaxis: a case report. J.Allergy Clin.Immunol. 1997;99(5):722-723. PubMed
    2. 31341. Anliker, M. D., Borelli, S., and Wuthrich, B. Occupational protein contact dermatitis from spices in a butcher: a new presentation of the mugwort-spice syndrome. Contact Dermatitis 2002;46(2):72-74. PubMed
    3. 46902. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  • An allergic reaction Worth acting on Additional detail

    Recorded for Cumin in the same Natural Medicines adverse-effect record shown under A severe allergic reaction above.

  • Stomach upset Additional detail

    Recorded for Cumin in the same Natural Medicines adverse-effect record shown under A severe allergic reaction above.

  • A skin rash Additional detail

    Recorded for Cumin in the same Natural Medicines adverse-effect record shown under A severe allergic reaction above.

Everything above comes from the Natural Medicines adverse-effect record for Cumin — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Avatrombopag Maleate’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Avatrombopag Maleate column appears here.

How to take them

Some Avatrombopag Maleate Products Have a Food Rule — Cumin Should Not Break It

At least one FDA label for a product containing Avatrombopag Maleate says to take it with food. If you take Cumin on an empty stomach out of habit, keep them separate — and take Avatrombopag Maleate with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Avatrombopag Maleate products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

Administer DOPTELET tablets and DOPTELET SPRINKLE with food.

From the Dosage and Administration section of the FDA label we read for Avatrombopag Maleate — where that label names a specific product, the instruction is that product's. See the Avatrombopag Maleate drug page ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

From our Q&A

Questions About Cumin or Avatrombopag Maleate

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Cumin or Avatrombopag Maleate, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Avatrombopag Maleate

This page covers Cumin only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Avatrombopag Maleate page lists 54 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), St. John's Wort (major), Bitter Melon (moderate), Black Pepper (moderate) and Bulbine Natalensis (moderate).

By severity: 2 major · 35 moderate · 17 minor.

From our pharmacist’s overview on the Avatrombopag Maleate page

“Avatrombopag maleate (Doptelet) exists to raise a low platelet count, so anything that drags its blood level down invites the bleeding risk it was prescribed to prevent. I would handle this list of 54 supplements with real care, and the two rated major come first.”

Reviewed by 2 · Jul 18, 2026

Open the Avatrombopag Maleate interaction page

One more smart check

Taking Cumin as Part of a Dietary Supplement Product? Check It for Interactions

We hold 279 real supplement products containing Cumin, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Cumin. Even though Cumin itself has no known interaction with Avatrombopag Maleate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Cumin and Avatrombopag Maleate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Cumin
Top 25%

#307 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Avatrombopag Maleate
Top 5%

#105 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Cumin reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Cumin and Avatrombopag Maleate records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Cumin

What is Cumin?

Cumin
  • Digestive upset
  • Bloating and gas
  • Appetite stimulation
  • Blood sugar support
  • Cholesterol support
  • Antimicrobial

Cumin is a common cooking spice that has a long history in traditional medicine for digestion and other complaints. Food amounts are generally safe for most people, but the evidence for medicinal or supplement-level benefits is limited and mostly early-stage. Talk with your pharmacist or doctor before using concentrated cumin supplements or oil.

Cuminum cyminum · Apiaceae · Seeds (fruit) and essential oil · Whole seeds, ground powder, capsules, extracts, and essential oil

An interaction check asks whether these two react with each other — it does not ask whether Cumin is a good idea for someone in your situation. Here is what our Cumin record says about it on its own.

Cumin: dosing

There is no well-established standardized medicinal dose for cumin. As a spice, it is used freely in cooking, which is considered safe for most people.For supplements, extracts, or essential oil, follow the directions on the product label and do not exceed the recommended amount.

From our Cumin monograph — the full record covers uses, side effects and every documented interaction.

Read the full Cumin monograph & all interactions
Medication

About Avatrombopag

What Is Avatrombopag Used For?

Brand name: Doptelet

Avatrombopag treats thrombocytopenia (a low platelet count that raises bleeding risk) in three groups of patients. Doptelet tablets are used in adults with chronic liver disease who need their platelet count raised before a medical procedure, and in adults with chronic immune thrombocytopenia (ITP) whose platelet count has not responded well enough to earlier treatments. Doptelet tablets are also used in children aged 6 years and older with persistent or chronic ITP who have not responded to prior treatment.

Doptelet Sprinkle (oral granules) is specifically indicated for children aged 1 year to less than 6 years with persistent or chronic ITP who have not responded adequately to a previous treatment.

See full Avatrombopag drug information
Keep checking

Other Drugs & Cumin

Browse every other medication we’ve checked against Cumin — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
211Moderate
0Minor
2,618No known interaction
211 Moderate 2,618 No interaction
Moderate

211 interactions

Showing 60 of 211 moderate interactions — see all 211 on the Cumin page.

No interaction 2,618 drugs checked — show the list

We also checked Cumin against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,618 medications checked with no known interaction — see the full Cumin list.

See the full Cumin interactions page
See every supplement checked against Avatrombopag Maleate, ranked by severity
Evidence & sources

Cumin References

The 10 references that drive our Cumin monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Anliker, M. D., Borelli, S., and Wuthrich, B. Occupational protein contact dermatitis from spices in a butcher: a new presentation of the mugwort-spice syndrome. Contact Dermatitis 2002;46(2):72-74. PubMed
  3. Dhandapani, S., Subramanian, V. R., Rajagopal, S., and Namasivayam, N. Hypolipidemic effect of Cuminum cyminum L. on alloxan-induced diabetic rats. Pharmacol.Res 2002;46(3):251-255. PubMed
  4. Sachin, B. S., Sharma, S. C., Sethi, S., Tasduq, S. A., Tikoo, M. K., Tikoo, A. K., Satti, N. K., Gupta, B. D., Suri, K. A., Johri, R. K., and Qazi, G. N. Herbal modulation of drug bioavailability: enhancement of rifampicin levels in plasma by herbal pro
  5. Jagtap, A. G. and Patil, P. B. Antihyperglycemic activity and inhibition of advanced glycation end product formation by Cuminum cyminum in streptozotocin induced diabetic rats. Food Chem.Toxicol. 5-6-2010; PubMed
  6. Srivastava, K. C. Extracts from two frequently consumed spices--cumin (Cuminum cyminum) and turmeric (Curcuma longa)--inhibit platelet aggregation and alter eicosanoid biosynthesis in human blood platelets. Prostaglandins Leukot.Essent.Fatty Acids 1989;3 PubMed
  7. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  8. Boxer, M., Roberts, M., and Grammer, L. Cumin anaphylaxis: a case report. J.Allergy Clin.Immunol. 1997;99(5):722-723. PubMed
  9. Karimian J, Farrokhzad A, Jalili C. The effect of cumin (Cuminum cyminum L.) supplementation on glycemic indices: A systematic review and meta-analysis of randomized controlled trials. Phytother Res 2021;35(8):4127-4135.
  10. Tavakoli-Rouzbehani OM, Faghfouri AH, Anbari M, et al. The effects of Cuminum cyminum on glycemic parameters: a systematic review and meta-analysis of controlled clinical trials. J Ethnopharmacol 2021;281:114510. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Cumin and Avatrombopag Maleate Together: Common Questions

Is it safe to take Cumin with Avatrombopag Maleate?
We do not list a known interaction between Cumin and Avatrombopag Maleate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Cumin and Avatrombopag Maleate at the same time of day?
At least one FDA label for a product containing Avatrombopag Maleate says to take it with food. If you take Cumin on an empty stomach out of habit, keep them separate and take Avatrombopag Maleate with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Avatrombopag Maleate products can differ — so check the directions on your own box. This is about absorption, not an interaction.
How was the Cumin and Avatrombopag Maleate combination checked?
Interactions in our licensed database are recorded against drug classes. Avatrombopag Maleate is filed under 2 classifications, and Cumin has documented interactions with 3 drug classes — none of Avatrombopag Maleate's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Cumin interact with any other medications?
Yes. Cumin has 211 documented drug interactions in our database — Avatrombopag Maleate is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Avatrombopag Maleate interact with any supplements?
Yes. Avatrombopag Maleate has documented interactions with 54 supplements in our database — Cumin is not one of them. The Avatrombopag Maleate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Cumin monograph Uses, safety profile, and every drug interaction in one place Avatrombopag drug information The full plain-English guide to this medication Avatrombopag Maleate supplement interactions Every supplement checked against Avatrombopag Maleate, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 10 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Avatrombopag Maleate and Cumin?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.