Drug & supplement interaction

Desert Parsley + Lidocaine

Lidocaine brand names: Xylocaine, Dilocaine, Lidoject-1, Xylocaine MPF, Nervocaine, and others.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Desert Parsley and Lidocaine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Desert Parsley and Lidocaine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Lidocaine and Desert Parsley in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Desert Parsley at all — not against Lidocaine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Desert Parsley safety at a glance

Desert Parsley overall Use caution Limited human safety data and a known risk of a measles-like skin rash in some users.
Pregnancy Avoid Not enough safety data; avoid use during pregnancy.
Breastfeeding Avoid Not enough safety data; avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Lidocaine and Desert Parsley? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Lidocaine’s Own FDA Label Lists

This is not an interaction — none of it involves Desert Parsley. These are the most notable effects listed in the ADVERSE REACTIONS section of Lidocaine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • A slow heartbeat Worth acting on
  • Wheezing Worth acting on
  • Confusion Worth acting on
  • Seizures Worth acting on
  • Shortness of breath Worth acting on mentioned in 3.8% of FDA reports for Lidocaine
  • Low mood Worth acting on
  • A severe allergic reaction Worth acting on
  • Hives Worth acting on
  • Bleeding or bruising Worth acting on
  • An allergic reaction Worth acting on

Showing the 10 most notable of 27 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Lidocaine. Read the label on DailyMed › Where a percentage is shown, it is the share of 96,036 voluntary FDA FAERS reports for Lidocaine that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Desert Parsley’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Desert Parsley side to compare — that is a limit of the record, not a statement that Desert Parsley has no side effects.

Everything else you take

See Every Supplement That Interacts With Lidocaine

This page covers Desert Parsley only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Lidocaine page lists 145 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Fever Bark (major), Grapefruit (major), St. John's Wort (major), 1,3-dmaa (moderate) and Acacia Rigidula (moderate).

By severity: 3 major · 111 moderate · 31 minor.

From our pharmacist’s overview on the Lidocaine page

“Lidocaine (Xylocaine) deserves genuine care on this page, and I would learn its three major-rated entries first. Grapefruit and St.”

Reviewed by 2 · Jul 18, 2026

Open the Lidocaine interaction page

How much people look this up

Where Desert Parsley and Lidocaine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Desert Parsley
Steady interest

#770 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Lidocaine
Top 10%

#232 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Desert Parsley is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Desert Parsley reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Desert Parsley and Lidocaine records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Desert Parsley

What is Desert Parsley?

  • Respiratory infections and colds
  • Cough and congestion
  • Flu-like illness
  • Immune support
  • Sore throat

Desert Parsley (Lomatium dissectum) is a root used in Native American and Western herbal traditions, mainly for colds, coughs, and respiratory infections. Modern scientific evidence in humans is very limited, and it can cause a widespread skin rash in some people, so use it cautiously and talk with your pharmacist or doctor first.

Lomatium dissectum · Apiaceae · Root · Tincture, capsules, dried root, tea, glycerite extract

An interaction check asks whether these two react with each other — it does not ask whether Desert Parsley is a good idea for someone in your situation. Here is what our Desert Parsley record says about it on its own.

Desert Parsley: dosing

There is no established standard dose for Desert Parsley. Traditional use varies widely depending on the form, whether it is a tincture, capsule, or tea.Because a safe and effective dose has not been defined in research, follow the directions on the product label and do not exceed them.

From our Desert Parsley monograph — the full record covers uses, side effects and every documented interaction.

Read the full Desert Parsley monograph & all interactions
Medication

About Lidocaine Transdermal Patch

What Is Lidocaine Transdermal Patch Used For?

Brand names: Xylocaine, Dilocaine, Lidoject-1, Xylocaine MPF, Nervocaine, Lidoject-2, Duo-Trach Kit, Octocaine, Lidoderm, Ztlido

Lidocaine skin patches are applied directly to the painful area to treat post-herpetic neuralgia (PHN) — the persistent burning or aching nerve pain that can remain after a shingles outbreak.

Lidoderm (lidocaine patch 5%) and ZTlido (lidocaine topical system 1.8%) are both indicated for this use in adults. Note that despite their different strengths, one ZTlido topical system provides equivalent lidocaine exposure to one Lidoderm patch.

Most-Reported Side Effects for Lidocaine

From FAERS, the FDA’s public side-effect reporting system (96,036 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Nausea 4,961 reports
Fatigue 4,867 reports
Headache 4,439 reports
Product quality issue 3,920 reports
Dyspnea 3,658 reports
See full Lidocaine Transdermal Patch drug information
Keep checking

Other Drugs & Desert Parsley

Browse every other medication we’ve checked against Desert Parsley — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Desert Parsley against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Desert Parsley list.

See the full Desert Parsley interactions page
See every supplement checked against Lidocaine, ranked by severity
Evidence & sources

Desert Parsley References

The 1 sources that drive our Desert Parsley monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Desert Parsley is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Using Dietary Supplements Wisely — NIH National Center for Complementary and Integrative Health (NCCIH) Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Desert Parsley and Lidocaine Together: Common Questions

Is it safe to take Desert Parsley with Lidocaine?
We do not list a known interaction between Desert Parsley and Lidocaine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Lidocaine interact with any supplements?
Yes. Lidocaine has documented interactions with 145 supplements in our database — Desert Parsley is not one of them. The Lidocaine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Desert Parsley monograph Uses, safety profile, and every drug interaction in one place Lidocaine Transdermal Patch drug information The full plain-English guide to this medication Lidocaine supplement interactions Every supplement checked against Lidocaine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Lidocaine and Desert Parsley?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.