Drug & supplement interaction

Dill + Ponesimod

Ponesimod brand name: Ponvory.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Dill and Ponesimod in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Dill and Ponesimod

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Ponesimod and Dill in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Dill safety at a glance

Dill overall Generally safe Generally safe in the amounts used in food.
Pregnancy Possibly Unsafe When used in medicinal amounts. Dill seed is used to stimulate menstrual flow. Theoretically, dill seed might adversely affect pregnancy. Read the full pregnancy detail
Breastfeeding Use caution Food amounts are likely fine, but the safety of medicinal doses is not well studied.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Ponesimod and Dill? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Ponesimod

Interactions in our licensed database are recorded against drug classes, not just single drug names. Ponesimod is filed under 3 classifications — qt interval-prolonging drugs, cytochrome p450 3a4 (cyp3a4) substrates, oral drugs. Dill has documented interactions with 2 drug classes — the most serious being antidiabetes drugs (moderate) and lithium (moderate) — and none of Ponesimod’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Dill Does Interact With Other Medications

Dill has 87 moderate known drug interactions in our database — Ponesimod isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Dill

Covers the 2,830 medications we’ve checked against Dill. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Dill and Ponesimod May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Swelling Additional detail

    Dill

    “Orally, there are case reports of individuals allergic to dill. In one case, symptoms, including swelling around the eyes, itching, rash, and chapped lips, occurred after a delay of 12 hours. In another case, immediate symptoms of anaphylaxis, as well as vomiting and diarrhea, occurred following intake and inhalation of foods cooked with dill.

    Topically, dill has resulted in contact dermatitis.”

    Dill · Natural Medicines adverse-effect record, reported in dermatitis.

    4 sources cited
    1. 47751. Freeman, G. L. Allergy to fresh dill. Allergy 1999;54(5):531-532. PubMed
    2. 47753. Chiu, A. M. and Zacharisen, M. C. Anaphylaxis to dill. Ann Allergy Asthma Immunol. 2000;84(5):559-560.
    3. 47767. Monteseirin, J., Perez-Formoso, J. L., Sanchez-Hernandez, M. C., Hernandez, M., Camacho, M. J., Bonilla, I., Guardia, P., and Conde, J. Occupational contact dermatitis to dill. Allergy 2002;57(9):866-867. PubMed
    4. 47773. Monteseirin, J., Perez-Formoso, J. L., Hernandez, M., Sanchez-Hernandez, M. C., Camacho, M. J., Bonilla, I., Chaparro, A., and Conde, J. Contact urticaria from dill. Contact Dermatitis 2003;48(5):275. PubMed

    Ponesimod

    Listed in the ADVERSE REACTIONS section of the FDA label for Ponesimod. Read the label on DailyMed ›

Reported for Dill but not commonly for Ponesimod: sun sensitivity, a severe allergic reaction, a skin rash and vomiting.

Effects for Ponesimod come from the ADVERSE REACTIONS section of its FDA label; effects for Dill come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Dill in Pregnancy & Breastfeeding

Pregnancy Possibly Unsafe

When used in medicinal amounts. Dill seed is used to stimulate menstrual flow. Theoretically, dill seed might adversely affect pregnancy.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Ponesimod

This page covers Dill only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ponesimod page lists 146 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).

By severity: 8 major · 98 moderate · 40 minor.

From our pharmacist’s overview on the Ponesimod page

“Someone managing relapsing MS with ponesimod (Ponvory) has real reason to read this list closely, since 8 of its 146 documented supplement interactions rate major. The largest group, 121 ingredients, works through CYP3A4, the liver enzyme that clears ponesimod.”

Reviewed by 2 · Jul 18, 2026

Open the Ponesimod interaction page

One more smart check

Taking Dill as Part of a Dietary Supplement Product? Check It for Interactions

We hold 123 real supplement products containing Dill, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Dill. Even though Dill itself has no known interaction with Ponesimod, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Dill and Ponesimod Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Dill
Top half

#481 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Ponesimod
Top half

#984 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Dill reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Dill and Ponesimod records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Dill

What is Dill?

  • Digestive upset and gas
  • Colic in infants (traditional)
  • Stimulating appetite
  • Bad breath
  • Menstrual discomfort

Dill is a common culinary herb that has long been used in traditional medicine for digestive complaints, but solid human evidence for any medicinal use is limited. It is generally considered safe in normal food amounts, while concentrated supplements or essential oil should be used with caution and discussed with a pharmacist or doctor.

Anethum graveolens · Apiaceae · Leaves (dill weed), seeds, and essential oil · Fresh or dried herb, seeds, tea, essential oil, capsules/extracts

An interaction check asks whether these two react with each other — it does not ask whether Dill is a good idea for someone in your situation. Here is what our Dill record says about it on its own.

Dill: dosing

There is no official or standardized medicinal dose for dill. As a food and seasoning, it is used freely to taste. As a tea, the seeds are sometimes steeped in hot water.For dill supplements, capsules, or extracts, the best advice is to follow the directions on the product label, since strength varies between products.

From our Dill monograph — the full record covers uses, side effects and every documented interaction.

Read the full Dill monograph & all interactions
Medication

About Ponesimod

What Is Ponesimod Used For?

Brand name: Ponvory

Ponvory (ponesimod) is approved for adults with relapsing forms of multiple sclerosis (MS). This includes clinically isolated syndrome (a first MS episode), relapsing-remitting MS, and active secondary progressive MS.

It is not approved for children, and it is only available as an oral tablet under the brand name Ponvory.

Most-Reported Side Effects for Ponesimod

From FAERS, the FDA’s public side-effect reporting system (428 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 35 reports
Dizziness 24 reports
Dyspnea 23 reports
Headache 22 reports
Nausea 14 reports
See full Ponesimod drug information
Keep checking

Other Drugs & Dill

Browse every other medication we’ve checked against Dill — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
87Moderate
0Minor
2,742No known interaction
Moderate

87 interactions

Showing 60 of 87 moderate interactions — see all 87 on the Dill page.

No interaction 2,742 drugs checked — show the list
Evidence & sources

Dill References

The 17 references that drive our Dill monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  4. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  5. Freeman, G. L. Allergy to fresh dill. Allergy 1999;54(5):531-532. PubMed
  6. Chiu, A. M. and Zacharisen, M. C. Anaphylaxis to dill. Ann Allergy Asthma Immunol. 2000;84(5):559-560.
  7. Monteseirin, J., Perez-Formoso, J. L., Sanchez-Hernandez, M. C., Hernandez, M., Camacho, M. J., Bonilla, I., Guardia, P., and Conde, J. Occupational contact dermatitis to dill. Allergy 2002;57(9):866-867. PubMed
  8. Monteseirin, J., Perez-Formoso, J. L., Hernandez, M., Sanchez-Hernandez, M. C., Camacho, M. J., Bonilla, I., Chaparro, A., and Conde, J. Contact urticaria from dill. Contact Dermatitis 2003;48(5):275. PubMed
  9. Kojuri, J., Vosoughi, A. R., and Akrami, M. Effects of anethum graveolens and garlic on lipid profile in hyperlipidemic patients. Lipids Health Dis. 2007;6:5. PubMed
  10. Panda, S. The effect of Anethum graveolens L. (dill) on corticosteroid induced diabetes mellitus: involvement of thyroid hormones. Phytother.Res 2008;22(12):1695-1697.
  11. Madani H, Mahmoodabady NA Vahdati A. Effects of hydroalchoholic [sic] extract of Anethum graveolens (DILL) on plasma glucose an [sic] lipid levels in diabetes induced rats. Iranian Journal of Diabetes & Lipid Disorders 2006;5(2):E13.
  12. Hekmatzadeh SF, Bazarganipour F, Malekzadeh J, Goodarzi F, Aramesh S. A randomized clinical trial of the efficacy of applying a simple protocol of boiled Anethum Graveolens seeds on pain intensity and duration of labor stages. Complement Ther Med. 2014;22 PubMed
  13. Sohm B, Cenizo V, André V, Zahouani H, Pailler-Mattei C, Vogelgesang B. Evaluation of the efficacy of a dill extract in vitro and in vivo. Int J Cosmet Sci. 2011;33(2):157-63.
  14. Hekmatzadeh SF, Bazarganipour F, Allan H, Aramesh S, Mohammadi J. Effects of boiled dill seed on anxiety during labor: A randomized clinical trial. Chin J Integr Med. 2020;26(2):100-105. PubMed
  15. Omidvar S, Nasiri-Amiri F, Bakhtiari A, Begum K. Clinical trial for the management dysmenorrhea using selected spices. Complement Ther Clin Pract. 2019;36:34-38. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Dill and Ponesimod Together: Common Questions

Is it safe to take Dill with Ponesimod?
We do not list a known interaction between Dill and Ponesimod. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Dill and Ponesimod have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Dill and Ponesimod combination checked?
Interactions in our licensed database are recorded against drug classes. Ponesimod is filed under 3 classifications, and Dill has documented interactions with 2 drug classes — none of Ponesimod's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Dill interact with any other medications?
Yes. Dill has 87 documented drug interactions in our database — Ponesimod is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Ponesimod interact with any supplements?
Yes. Ponesimod has documented interactions with 146 supplements in our database — Dill is not one of them. The Ponesimod interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Ponesimod and Dill?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.