Herb & supplement monograph

Dill Drug Interactions, Uses, Effectiveness, Safety & More

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS ·Updated July 2026

What is this page for?

First and foremost: how Dill interacts with medications. The heart of this page is the interaction list — every drug Dill is known to interact with, and how serious each one is.

But these pages have grown well beyond that into a full monograph — what Dill is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy

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On this page

Dill Drug Interactions: The Bottom Line

From the HelloPharmacist Editorial Team · Updated July 2026

Based on the available evidence, the overall risk of a clinically significant Dill drug interaction appears low for most people, though a couple of medication types deserve extra care. None of the listed interactions are rated major, and the concerns rest largely on animal research or theoretical reasoning rather than proven effects in people.

Interactions deserving the most attention

The interaction best worth knowing about involves lithium. Because dill may act as a mild diuretic, it could reduce how much lithium the body clears, which matters since lithium levels must stay within a narrow range. People taking diabetes medications should also be aware that dill extract lowered blood sugar in animal studies, so combining the two could in theory add to that effect and make blood sugar monitoring more important.

What the rest of the list means

Although dill appears alongside a long list of medications, that number mostly reflects how many drugs fall into these two broad groups. The concerns are largely predicted from animal studies or from dill's possible diuretic effect, not from documented harm in people, so most combinations are unlikely to cause a noticeable problem.

Check your medications against Dill

Based on HelloPharmacist’s Dill interaction data and reviewed under our editorial standards.

Interaction report

Drugs that interact with Dill

87 medications have a known interaction with Dill, graded by severity. Select any drug for the full evidence-based detail.

Don’t want to scroll the list? Just ask.

Tell us the medications you take and we’ll check each one against Dill using our pharmacist-reviewed interaction data.

AI summaries are generated from our Dill interaction data for education only — always confirm with your pharmacist. How we use AI

2,830 drugs

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
Each drug listed above links to the full report for that exact Dill combination — clinical detail, likelihood, evidence level, and citations.
Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

The big picture

The kinds of drugs Dill affects

Every type of medication (drug category) Dill is known to interact with. Open any category for the detail — or search your exact drug in the checker above.

All 2 drug categories Dill interacts with

Antidiabetes DrugsLithium

Antidiabetes Drugs

Theoretically, dill extract might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia. Animal research shows that dill extract can reduce blood sugar levels. Monitor blood glucose levels closely. Dose adjustments might be necessary.
Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence D

Lithium

Dill is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, dill might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D

Monograph

Dill: Uses, Safety & Side Effects

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Reviewed July 2026 ·

The bottom line

Dill is a common culinary herb that has long been used in traditional medicine for digestive complaints, but solid human evidence for any medicinal use is limited. It is generally considered safe in normal food amounts, while concentrated supplements or essential oil should be used with caution and discussed with a pharmacist or doctor.

Scientific name: Anethum graveolens
Family: Apiaceae
Part used: Leaves (dill weed), seeds, and essential oil
Common forms: Fresh or dried herb, seeds, tea, essential oil, capsules/extracts

People commonly use it for

Digestive upset and gas
Colic in infants (traditional)
Stimulating appetite
Bad breath
Menstrual discomfort

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance

OverallLikely safe

Generally safe in the amounts used in food.

PregnancyPossibly Unsafe

When used in medicinal amounts. Dill seed is used to stimulate menstrual flow. Theoretically, dill seed might adversely affect pregnancy.

Read the full pregnancy detail

BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid amounts greater than those found in foods.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Jump to a section

Overview

Dill (Anethum graveolens) is a flowering herb in the same plant family as parsley, fennel, and carrots. It is grown around the world and is widely used as a cooking herb, especially with fish, pickles, soups, and sauces.

Both the feathery leaves (called dill weed) and the small flat seeds are used. People also press the plant to make dill essential oil. For centuries, dill has been used in traditional medicine, mostly for stomach and digestive complaints. Today it is sold as fresh and dried herb, tea, seeds, capsules, and essential oil.

How it works

Dill contains aromatic plant compounds, including substances in its essential oil such as carvone and limonene, along with flavonoids and other antioxidants. These compounds give dill its distinctive smell and may help relax the muscles of the digestive tract, which is one proposed reason it has been used for gas and cramping.

Laboratory and animal research suggests dill extracts may have antioxidant and antimicrobial effects, and some studies hint at possible effects on blood sugar and cholesterol. It is important to know that these findings are mostly early-stage and do not prove the same effects happen in people.

Effectiveness

Does Dill work?

Here’s what the research actually shows for each use — graded by Natural Medicines and reviewed by Dr. Brian Staiger, PharmD.

Evidence overview · 8 uses evaluated

8 Insufficient evidence

How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.

2Likely EffectiveGood evidence, though not yet conclusive.

3Possibly EffectiveSome evidence suggests a benefit.

4Possibly IneffectiveSome evidence it may not help.

5Likely IneffectiveFairly strong evidence it doesn’t help.

6IneffectiveStrong evidence it doesn’t work.

7Insufficient Reliable Evidence to RateToo little research to say either way.

For Dill, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.

Also studied for 8 conditions — evidence insufficient to rate

Insufficient Reliable Evidence To Rate Aging skin