Drug & supplement interaction

Dill + Nateglinide

Nateglinide brand name: Starlix.

Moderate Interaction
Medically reviewed by · Updated September 2026
The bottom line Moderate

Dill has a moderate interaction with Nateglinide. Theoretically, dill extract might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.

Read the full interaction report
SeverityModerate
LikelihoodPossible
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Dill and Nateglinide

Here is the interaction we found between these two, with the evidence behind it.

Moderate

ANTIDIABETES DRUGS

Why this applies to Nateglinide

Nateglinide falls under ANTIDIABETES DRUGS — the group Dill interacts with.

Theoretically, dill extract might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia. Animal research shows that dill extract can reduce blood sugar levels. Monitor blood glucose levels closely. Dose adjustments might be necessary.
Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.
Severity Moderate Likelihood Possible Evidence D

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the simple version: nateglinide (Starlix) already pushes your pancreas to release insulin and lower your blood sugar. Dill, mostly in concentrated extract or essential oil form, may nudge blood sugar down a little too. Put the two together and the effects could stack, which means a slightly higher chance of hypoglycemia (low blood sugar). That can show up as shakiness, sweating, dizziness, a fast heartbeat, hunger, or feeling confused.

I want to be honest about how strong this evidence is: it's theoretical and comes from lab and animal studies, not from people. Normal cooking amounts of dill in your food are very unlikely to cause a problem. If you're thinking about a daily dill supplement, just check your blood sugar more closely and chat with your pharmacist or doctor first.

Contact Dr. Brian directly if you have additional questions on this interaction
References
  1. Panda, S. The effect of Anethum graveolens L. (dill) on corticosteroid induced diabetes mellitus: involvement of thyroid hormones. Phytother.Res 2008;22(12):1695-1697.
  2. Madani H, Mahmoodabady NA Vahdati A. Effects of hydroalchoholic [sic] extract of Anethum graveolens (DILL) on plasma glucose an [sic] lipid levels in diabetes induced rats. Iranian Journal of Diabetes & Lipid Disorders 2006;5(2):E13.

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Dill Also Interacts With Other Medications

Dill has 86 moderate known drug interactions in our database — the Nateglinide one above is one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. Nateglinide)
Taking anything else?

Check Another of Your Medications Against Dill

Covers the 2,830 medications we’ve checked against Dill. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Nateglinide

This page covers Dill only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Nateglinide page lists 290 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Siberian Cocklebur (major), Acai (moderate), Adrafinil (moderate) and African Wild Potato (moderate).

By severity: 2 major · 241 moderate · 47 minor.

From our pharmacist’s overview on the Nateglinide page

“People who take nateglinide (Starlix) with meals for type 2 diabetes are often drawn to supplements marketed for blood sugar, and that overlap is why these 290 interactions warrant real caution. Some 239 of the ingredients affect blood sugar on their own, most pushing it lower, so stacking them on nateglinide raises the odds of hypogly…”

Reviewed by 2 · Jul 18, 2026

Open the Nateglinide interaction page

One more smart check

Taking Dill as Part of a Dietary Supplement Product? Check It for Interactions

We hold 123 real supplement products containing Dill, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Dill. Your product may carry other ingredients that interact with Nateglinide too, on top of Dill — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Dill and Nateglinide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Dill
Top half

#449 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Nateglinide
Top half

#1,352 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Dill

What is Dill?

  • Digestive upset and gas
  • Colic in infants (traditional)
  • Stimulating appetite
  • Bad breath
  • Menstrual discomfort

Dill is a common culinary herb that has long been used in traditional medicine for digestive complaints, but solid human evidence for any medicinal use is limited. It is generally considered safe in normal food amounts, while concentrated supplements or essential oil should be used with caution and discussed with a pharmacist or doctor.

Read the full Dill monograph & all interactions
Medication

About Nateglinide

What Is Nateglinide Used For?

Brand name: Starlix

Nateglinide is used along with diet and exercise to improve blood sugar (glycemic) control in adults with type 2 diabetes. The supplied tablet labels, including the plain, film-coated and coated tablets, all list this same use.

It is not for people with type 1 diabetes or for treating diabetic ketoacidosis (a dangerous buildup of acids in the blood).

See full Nateglinide drug information
Keep checking

Other Drugs & Dill

Browse every other medication we’ve checked against Dill — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
86 Moderate 2,743 No interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Dill page.

No interaction 2,743 drugs checked — show the list

We also checked Dill against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Dill list.

See the full Dill interactions page
See every supplement checked against Nateglinide, ranked by severity
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Dill monograph › Uses, safety, and every drug interaction in one place Nateglinide supplement interactions › Every supplement checked against Nateglinide, ranked by severity Nateglinide drug information › The full plain-English guide to this medication Supplement interaction checker › Check any supplement or product against your medications Browse medications A–Z › Every drug we've checked against herbs & supplements Ask a pharmacist › Free, personal answer from our licensed team
Pharmacist Counseling Corner

Taking Dill and Nateglinide Together: Common Questions

Can you take Dill with Nateglinide?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Dill and Nateglinide interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Nateglinide and Dill?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.