Drug & supplement interaction

Dill + Pregabalin

Pregabalin brand names: Lyrica, Lyrica CR.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Oct 4, 2026
The bottom line No known interaction

We found no known interaction between Dill and Pregabalin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Dill and Pregabalin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Pregabalin and Dill in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Dill safety at a glance

Dill overall Generally safe Generally safe in the amounts used in food.
Pregnancy Possibly Unsafe When used in medicinal amounts. Dill seed is used to stimulate menstrual flow. Theoretically, dill seed might adversely affect pregnancy. Read the full pregnancy detail
Breastfeeding Use caution Food amounts are likely fine, but the safety of medicinal doses is not well studied.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Pregabalin and Dill? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Pregabalin

Interactions in our licensed database are recorded against drug classes, not just single drug names. Pregabalin is filed under 3 classifications — including cns depressants, oral drugs. Dill has documented interactions with 2 drug classes — the most serious being antidiabetes drugs (moderate) and lithium (moderate) — and none of Pregabalin’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Dill Does Interact With Other Medications

Dill has 87 moderate known drug interactions in our database — Pregabalin isn’t one of them. If you take anything else, check it against the full list below.

Moderate 87 No known interaction 2,743 (incl. Pregabalin)
Taking anything else?

Check Another of Your Medications Against Dill

Covers the 2,830 medications we’ve checked against Dill. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Dill and Pregabalin May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • A severe allergic reaction Worth acting on Additional detail

    Dill

    “Orally, there are case reports of individuals allergic to dill. In one case, symptoms, including swelling around the eyes, itching, rash, and chapped lips, occurred after a delay of 12 hours. In another case, immediate symptoms of anaphylaxis, as well as vomiting and diarrhea, occurred following intake and inhalation of foods cooked with dill.

    Topically, dill has resulted in contact dermatitis.”

    Dill · Natural Medicines adverse-effect record, reported in dermatitis.

    4 sources cited
    1. 47751. Freeman, G. L. Allergy to fresh dill. Allergy 1999;54(5):531-532. PubMed
    2. 47753. Chiu, A. M. and Zacharisen, M. C. Anaphylaxis to dill. Ann Allergy Asthma Immunol. 2000;84(5):559-560.
    3. 47767. Monteseirin, J., Perez-Formoso, J. L., Sanchez-Hernandez, M. C., Hernandez, M., Camacho, M. J., Bonilla, I., Guardia, P., and Conde, J. Occupational contact dermatitis to dill. Allergy 2002;57(9):866-867. PubMed
    4. 47773. Monteseirin, J., Perez-Formoso, J. L., Hernandez, M., Sanchez-Hernandez, M. C., Camacho, M. J., Bonilla, I., Chaparro, A., and Conde, J. Contact urticaria from dill. Contact Dermatitis 2003;48(5):275. PubMed

    Pregabalin

    Listed in the ADVERSE REACTIONS section of the FDA label for Pregabalin. Read the label on DailyMed ›

  • Sun sensitivity Additional detail

    Dill

    “Orally, dill is well tolerated when used in amounts commonly found in foods. Dill seems to be well tolerated when used as medicine (12). However, a thorough evaluation of safety outcomes has not been conducted. Some people are allergic to dill.

    Topically, photodermatosis is possible after contact with juice from freshly harvested plants (19). Dill can also cause contact dermatitis (19,47767, 47773).”

    Dill · Natural Medicines adverse-effect record, reported in dermatitis.

    5 sources cited
    1. 4912. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
    2. 12. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
    3. 47751. Freeman, G. L. Allergy to fresh dill. Allergy 1999;54(5):531-532. PubMed
    4. 47753. Chiu, A. M. and Zacharisen, M. C. Anaphylaxis to dill. Ann Allergy Asthma Immunol. 2000;84(5):559-560.
    5. 19. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

    Pregabalin

    Listed in the ADVERSE REACTIONS section of the FDA label for Pregabalin. Read the label on DailyMed ›

  • Itching / Swelling / Diarrhea / Vomiting Additional detail

    Dill

    Recorded for Dill in the same Natural Medicines adverse-effect record shown under A severe allergic reaction above.

    Pregabalin

    Listed in the ADVERSE REACTIONS section of the FDA label for Pregabalin. Read the label on DailyMed ›

  • A skin rash Additional detail

    Dill

    Recorded for Dill in the same Natural Medicines adverse-effect record shown under Sun sensitivity above.

    Pregabalin

    Listed in the ADVERSE REACTIONS section of the FDA label for Pregabalin. Read the label on DailyMed ›

Effects for Pregabalin come from the ADVERSE REACTIONS section of its FDA label; effects for Dill come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Dill in Pregnancy & Breastfeeding

Pregnancy Possibly Unsafe

When used in medicinal amounts. Dill seed is used to stimulate menstrual flow. Theoretically, dill seed might adversely affect pregnancy.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Overlapping uses

What Pregabalin Is Prescribed For, and What Dill Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Pregabalin is a prescription medicine with approved uses on its FDA label. Dill is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Pregabalin is prescribed for: Pregabalin treats several types of nerve-related pain. These include neuropathic pain from diabetic peripheral neuropathy (nerve damage from diabetes) and postherpetic neuralgia (nerve pain that lingers after shingles). Lyrica and pregabalin capsules and oral solution are also used for fibromyalgia, neuropathic pain from spinal cord injury, and as add-on therapy for partial-onset seizures. The seizure age range differs by product: Lyrica capsules and oral solution and pregabalin oral solution list ages 1 month and older, while generic pregabalin capsules list ages 17 and older.

Read the rest of what Pregabalin is prescribed for

Lyrica CR and pregabalin extended-release tablets are used only for diabetic nerve pain and postherpetic neuralgia. Their efficacy has not been established for fibromyalgia or for seizures.

Dill has been studied for:

  • Diabetes studied, not established Dill has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Dill for diabetes

    It is unclear if oral dill is beneficial for diabetes.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Pregabalin on your own; if you are taking Dill for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Dill or Pregabalin

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Dill or Pregabalin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Pregabalin

This page covers Dill only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Pregabalin page lists 95 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Kava (major).

By severity: 7 major · 73 moderate · 15 minor.

From our pharmacist’s overview on the Pregabalin page

“Pregabalin (Lyrica) calms overactive nerves, which is how it eases nerve pain, seizures, and anxiety, and that calming action stacks with almost everything on this list. Of the 95 supplements and herbs, the large majority add their own sedation on top of pregabalin's, and a few can tip that into genuine danger, with deep sedation and s…”

Reviewed by 2 · Jul 18, 2026

Open the Pregabalin interaction page

One more smart check

Taking Dill as Part of a Dietary Supplement Product? Check It for Interactions

We hold 123 real supplement products containing Dill, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Dill. Even though Dill itself has no known interaction with Pregabalin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Dill and Pregabalin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Dill
Top half

#436 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Pregabalin
Top 5%

#81 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Dill reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Dill and Pregabalin records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Dill

What is Dill?

  • Digestive upset and gas
  • Colic in infants (traditional)
  • Stimulating appetite
  • Bad breath
  • Menstrual discomfort

Dill is a common culinary herb that has long been used in traditional medicine for digestive complaints, but solid human evidence for any medicinal use is limited. It is generally considered safe in normal food amounts, while concentrated supplements or essential oil should be used with caution and discussed with a pharmacist or doctor.

Anethum graveolens · Apiaceae · Leaves (dill weed), seeds, and essential oil · Fresh or dried herb, seeds, tea, essential oil, capsules/extracts

An interaction check asks whether these two react with each other — it does not ask whether Dill is a good idea for someone in your situation. Here is what our Dill record says about it on its own.

Dill: dosing

There is no official or standardized medicinal dose for dill. As a food and seasoning, it is used freely to taste. As a tea, the seeds are sometimes steeped in hot water.For dill supplements, capsules, or extracts, the best advice is to follow the directions on the product label, since strength varies between products.

From our Dill monograph — the full record covers uses, side effects and every documented interaction.

Read the full Dill monograph & all interactions
Medication

About Pregabalin

What Is Pregabalin Used For?

Brand names: Lyrica, Lyrica CR

Pregabalin treats several types of nerve-related pain. These include neuropathic pain from diabetic peripheral neuropathy (nerve damage from diabetes) and postherpetic neuralgia (nerve pain that lingers after shingles).

Lyrica and pregabalin capsules and oral solution are also used for fibromyalgia, neuropathic pain from spinal cord injury, and as add-on therapy for partial-onset seizures. The seizure age range differs by product: Lyrica capsules and oral solution and pregabalin oral solution list ages 1 month and older, while generic pregabalin capsules list ages 17 and older. Lyrica CR and pregabalin extended-release tablets are used only for diabetic nerve pain and postherpetic neuralgia. Their efficacy has not been established for fibromyalgia or for seizures.

See full Pregabalin drug information
Keep checking

Other Drugs & Dill

Browse every other medication we’ve checked against Dill — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
87Moderate
0Minor
2,742No known interaction
87 Moderate 2,742 No interaction
Moderate

87 interactions

Showing 60 of 87 moderate interactions — see all 87 on the Dill page.

No interaction 2,742 drugs checked — show the list

We also checked Dill against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,742 medications checked with no known interaction — see the full Dill list.

See the full Dill interactions page
See every supplement checked against Pregabalin, ranked by severity
Evidence & sources

Dill References

The 10 references that drive our Dill monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  4. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  5. Freeman, G. L. Allergy to fresh dill. Allergy 1999;54(5):531-532. PubMed
  6. Chiu, A. M. and Zacharisen, M. C. Anaphylaxis to dill. Ann Allergy Asthma Immunol. 2000;84(5):559-560.
  7. Monteseirin, J., Perez-Formoso, J. L., Sanchez-Hernandez, M. C., Hernandez, M., Camacho, M. J., Bonilla, I., Guardia, P., and Conde, J. Occupational contact dermatitis to dill. Allergy 2002;57(9):866-867. PubMed
  8. Monteseirin, J., Perez-Formoso, J. L., Hernandez, M., Sanchez-Hernandez, M. C., Camacho, M. J., Bonilla, I., Chaparro, A., and Conde, J. Contact urticaria from dill. Contact Dermatitis 2003;48(5):275. PubMed
  9. Panda, S. The effect of Anethum graveolens L. (dill) on corticosteroid induced diabetes mellitus: involvement of thyroid hormones. Phytother.Res 2008;22(12):1695-1697.
  10. Madani H, Mahmoodabady NA Vahdati A. Effects of hydroalchoholic [sic] extract of Anethum graveolens (DILL) on plasma glucose an [sic] lipid levels in diabetes induced rats. Iranian Journal of Diabetes & Lipid Disorders 2006;5(2):E13.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Dill and Pregabalin Together: Common Questions

Is it safe to take Dill with Pregabalin?
We do not list a known interaction between Dill and Pregabalin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Dill and Pregabalin have any of the same side effects?
Yes — our sources link each of them separately to 7 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Are Dill and Pregabalin used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Dill in each. That is a conversation for your prescriber, especially if Pregabalin is being adjusted to a target.
How was the Dill and Pregabalin combination checked?
Interactions in our licensed database are recorded against drug classes. Pregabalin is filed under 3 classifications, and Dill has documented interactions with 2 drug classes — none of Pregabalin's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Dill interact with any other medications?
Yes. Dill has 87 documented drug interactions in our database — Pregabalin is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Pregabalin interact with any supplements?
Yes. Pregabalin has documented interactions with 95 supplements in our database — Dill is not one of them. The Pregabalin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Dill monograph Uses, safety profile, and every drug interaction in one place Pregabalin drug information The full plain-English guide to this medication Pregabalin supplement interactions Every supplement checked against Pregabalin, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 10 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Pregabalin and Dill?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.