Dyer's Broom - Aspirin, Caffeine, Dihydrocodeine Bitartrate Interaction
Herbal: Dyer's Broom
Also Known As: Genista tinctoria, Broom Flower, Dyers Broom, Dyer's Greenwood, Dyer's Weed, Dyer's Whin, Fleur à Teindre, Furze, Genestrelle, Genêt Bâtard, Genêt des Teinturiers, Genette, Green Broom, Greenweed, Herbe à Jaunir, Herbe à Teindre, Petit Gênet, Spargelle, Wood Waxen
Drug: Aspirin, Caffeine, Dihydrocodeine Bitartrate
Brand names:
Synalgos DC

Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 04, 2025
Interaction Details
Aspirin, Caffeine, Dihydrocodeine Bitartrate is classified as belonging to the following category: Caffeine
Theoretically, dyer's broom might reduce the clearance of caffeine.
Dyer's broom contains genistein. Taking genistein 1 gram daily for 14 days seems to inhibit caffeine clearance and metabolism in healthy females. This effect has been attributed to inhibition of the cytochrome P450 1A2 (CYP1A2) enzyme, which is involved in caffeine metabolism. It is unclear if this effect occurs with the lower amounts of genistein found in dyer's broom.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Chen, Y., Xiao, C. Q., He, Y. J., Chen, B. L., Wang, G., Zhou, G., Zhang, W., Tan, Z. R., Cao, S., Wang, L. P., and Zhou, H. H. Genistein alters caffeine exposure in healthy female volunteers. Eur.J Clin.Pharmacol. 2011;67(4):347-353.
Dyer's Broom Overview

Dyer's Broom - More Interactions
Dyer's Broom interacts with 29 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
Unknown | No interactions have been reported or no interaction data is currently available. |
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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Drug descriptions are provided by MedlinePlus.