What Supplements Interact with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Aspirin, Caffeine, Dihydrocodeine Bitartrate brand name: Synalgos DC. Every interaction below applies to the brands too.
Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy
What is this page for?
One answer, for one medication: what supplements and herbal products interact with Aspirin, Caffeine, Dihydrocodeine Bitartrate? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.
This page covers supplement interactions only — to check Aspirin, Caffeine, Dihydrocodeine Bitartrate against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy
398 supplements and herbal ingredients have interactions with Aspirin, Caffeine, Dihydrocodeine Bitartrate on file in the HelloPharmacist interaction database — 17 rated major, 334 moderate, and 47 minor. The most serious involve Beer, Grapefruit, Siberian Cocklebur, Wine and 1,4-butanediol.
Our assessment: with 17 major-rated interactions on the list, this one deserves real attention — know the major entries before combining anything with Aspirin, Caffeine, Dihydrocodeine Bitartrate.
Ranked by severity below. Every entry links to the full pharmacist-reviewed report for that exact combination — what can happen, how likely it is, and what to do about it.
This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓
Aspirin, Caffeine, Dihydrocodeine Bitartrate: Top Interactions at a Glance
The Aspirin, Caffeine, Dihydrocodeine Bitartrate supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.
Showing the 12 highest-ranked of 398 interacting ingredients — plus 1,054 more checked with no known interaction. See the complete ranked list.
The Most-Checked Aspirin, Caffeine, Dihydrocodeine Bitartrate Combinations Today
The Aspirin, Caffeine, Dihydrocodeine Bitartrate + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.
Theoretically, niacin may have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full interaction Minor Likelihood Possible Adenosine + Aspirin, Caffeine, Dihydrocodeine BitartrateiMethylxanthines are competitive antagonists of adenosine and can block its pharmacologic effects.
Read the full interaction Moderate Likelihood Possible Flaxseed Oil + Aspirin, Caffeine, Dihydrocodeine BitartrateiTheoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full interaction Moderate Likelihood Unlikely Niacinamide + Aspirin, Caffeine, Dihydrocodeine BitartrateiTheoretically, niacinamide may have additive effects when used with anticoagulant or antiplatelet drugs, especially in patients on hemodialysis.
Read the full interaction Moderate Likelihood Possible Black Currant + Aspirin, Caffeine, Dihydrocodeine BitartrateiTheoretically, black currant seed oil might increase the risk of bleeding if used in combination with anticoagulant or antiplatelet drugs.
Read the full interaction Minor Likelihood Unlikely Diindolylmethane + Aspirin, Caffeine, Dihydrocodeine BitartrateiTheoretically, diindolylmethane might lower serum levels of CYP1A2 substrates.
Read the full interactionEvery Supplement Checked Against Aspirin, Caffeine, Dihydrocodeine Bitartrate
All 1,452 ingredients in our database, ranked by severity — 398 with a Aspirin, Caffeine, Dihydrocodeine Bitartrate interaction on file and 1,054 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.
Looking for an interaction with a specific supplement product? Search products instead ↓
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Beer Likely
What it is: Beer is an alcoholic beverage that contains some minerals, B vitamins, and plant compounds from hops and grain, but it is not a health suppl...
Concomitant use may increase sedative and other adverse effects.
Read the full Beer + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGrapefruitCitrus Paradisi Likely
What it is: Grapefruit is a nutritious citrus fruit rich in vitamin C and other nutrients, and it is generally safe to eat.
Grapefruit juice can increase levels of drugs metabolized by CYP3A4.
Read the full Grapefruit + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSiberian Cocklebur Likely
What it is: Siberian cocklebur is a fruit used in traditional Chinese and other Asian herbal medicine, mainly for nasal congestion, sinus issues, and al...
Siberian cocklebur can adversely affect the kidney.
Read the full Siberian Cocklebur + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionWine Likely
What it is: Wine is an alcoholic beverage made from fermented grapes and is not a true dietary supplement or medicine.
Concomitant use may increase sedative and other adverse effects.
Read the full Wine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interaction1,4-butanediolOne Comma Four, one Four Bdo, one Four Bee, +1 more Probable
What it is: 1,4-butanediol is a toxic industrial chemical, not a safe dietary supplement.
Theoretically, concomitant use of 1,4-butanediol with CNS depressants may potentiate respiratory and CNS depression.
Read the full 1,4-butanediol + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionActivated CharcoalActivated Carbon, animal Charcoal, carbo Vegetabilis, +13 more Probable
What it is: Activated charcoal is a highly porous form of carbon that can bind certain substances in the gut, and it is used in hospitals to treat some...
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionDanshenSalvia Bowleyana, ch'ih Shen, chinese Red Sage, +15 more Probable
What it is: Danshen is a root used in traditional Chinese medicine, mainly for heart and circulation problems.
Theoretically, danshen may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Danshen + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionEphedraEphedra Distachya, belcho, cao Mahuang, +13 more Probable
What it is: Ephedra (ma huang) contains powerful stimulants like ephedrine that affect the heart and nervous system.
Theoretically, concomitant use might increase the risk for serious adverse effects.
Read the full Ephedra + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGamma-hydroxybutyrate (ghb) Probable
What it is: GHB (gamma-hydroxybutyrate) is a powerful central nervous system depressant that is NOT a safe dietary supplement.
GHB may increase the risk of serious CNS and respiratory depression.
Read the full Gamma-hydroxybutyrate (ghb) + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionKavaPiper Methysticum, ava Pepper, ava Root, +20 more Probable
What it is: Kava is a Pacific Island plant traditionally used to promote relaxation and ease anxiety, and some studies suggest it may help mild anxiety.
Combining kava with CNS depressants can have additive sedative effects.
Read the full Kava + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionL-tryptophanL-triptofano, l-trypt, l-tryptophane, +1 more Probable
What it is: L-tryptophan is an essential amino acid the body uses to make serotonin and melatonin, and people take it to support sleep and mood.
Theoretically, concomitant use of L-tryptophan with CNS depressants might cause additive sedative effects.
Read the full L-tryptophan + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPeyote Probable
What it is: Peyote is a small spineless cactus that contains mescaline, a powerful hallucinogen.
Concomitant use of peyote with stimulant drugs may increase the risk of adverse CNS effects.
Read the full Peyote + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPiracetam Probable
What it is: Piracetam is a synthetic 'nootropic' drug studied mainly for cognitive decline, myoclonus, and certain neurological conditions, but evidence...
Theoretically, concomitant use of piracetam and anticoagulant/antiplatelet drugs might increase the risk of bleeding.
Read the full Piracetam + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionRauvolfia Vomitoria Probable
What it is: Rauvolfia vomitoria is an African shrub whose root contains powerful alkaloids, including reserpine, that have historically been used for hi...
Theoretically, concomitant use might cause additive effects.
Read the full Rauvolfia Vomitoria + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSida CordifoliaAbutilon En Épi, bala, bariar, +15 more Probable
What it is: Sida cordifolia (bala or country mallow) is a traditional Ayurvedic plant that naturally contains ephedrine, a powerful stimulant.
Theoretically, Sida cordifolia might increase the risk of adverse cardiovascular effects when taken with stimulant drugs.
Read the full Sida Cordifolia + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSt. John's WortHypericum Perforatum, amber Touch-and-heal, barbe De Saint-jean, +13 more Probable
AsarabaccaAsarum Europaeum, asara, asari Herba, +12 more Possible
What it is: Asarabacca is a European woodland plant traditionally used to clear the nose, cause sweating, or trigger vomiting, but it is rarely used tod...
Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.
Read the full Asarabacca + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAyahuascaAppane, ayahoasca, caapi, +19 more Probable
What it is: Ayahuasca is a powerful psychoactive brew that combines a DMT-containing plant with a vine that allows the DMT to take effect, causing inten...
Theoretically, ayahuasca might increase plasma concentrations of CYP2D6 substrates.
Read the full Ayahuasca + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBlack Tea Probable
What it is: Black tea is a popular caffeinated drink made from the fully oxidized leaves of the Camellia sinensis plant, and it contains caffeine and an...
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Black Tea + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBridelia Probable
What it is: Bridelia is a group of tropical plants, with Bridelia ferruginea widely used in traditional African medicine for diabetes, infections, and d...
In animals, orally administered extracts of Bridelia ferruginea stem bark inhibit ADP/adrenaline-induced thrombosis by approximately 62%.Theoretically, Bridelia might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Bridelia + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCaffeine Probable
What it is: Caffeine is a natural stimulant found in coffee, tea, and many other plants and products.
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Caffeine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCannabidiol (cbd) Probable
What it is: CBD is a compound from the cannabis (hemp) plant that does not cause a 'high.' It has strong evidence only for certain rare seizure disorder...
Cannabidiol may increase levels of drugs metabolized by CYP1A2.
Read the full Cannabidiol (cbd) + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCocoaTheobroma Cacao, chocolat, chocolat Noir, +14 more Probable
What it is: Cocoa is rich in plant compounds called flavanols that may modestly support blood vessel function and blood pressure, but most chocolate pro...
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Cocoa + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCoffee Probable
What it is: Coffee is a widely consumed beverage made from roasted coffee beans, valued mainly for its caffeine, which boosts alertness and energy.
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Coffee + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCoffee CharcoalCafé Arabica, café Carbonisé, café Robusta, +5 more Probable
What it is: Coffee charcoal is made by roasting green coffee beans until they turn black, creating a charcoal-like material used traditionally for diarr...
Coffee charcoal can reduce the absorption of orally administered drugs and should be separated from oral drug administration by at least two hours.
Read the full Coffee Charcoal + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCola NutCola Acuminata, bissey Nut, bissy Nut, +10 more Probable
What it is: Cola nut is a caffeine-containing seed from West Africa used mainly as a natural stimulant for energy and alertness.
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Cola Nut + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionEchinaceaAmerican Cone Flower, black Sampson, black Susans, +7 more Probable
What it is: Echinacea is a popular herb taken to help prevent or shorten the common cold, but study results are mixed and the overall benefit appears sm...
Echinacea can increase plasma levels of caffeine by inhibiting its metabolism.
Read the full Echinacea + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionEuropean MandrakeMandragora Officinarum, alraunwurzel, mandragora, +7 more Probable
What it is: European mandrake is a highly toxic plant from the nightshade family that was used in ancient and medieval times as a sedative and pain reli...
Theoretically, concurrent use might increase absorption of some drugs because of inhibited gastrointestinal (GI) motility caused by European mandrake.
Read the full European Mandrake + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionEvodia Probable
What it is: Evodia is a fruit used in traditional Chinese medicine, most often for digestive complaints, headaches, and menstrual pain.
Evodia might reduce the levels and clinical effects of CYP1A2 substrates through induction of CYP1A2.
Read the full Evodia + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionFever BarkAlstonia Constricta, alstonia Bark, australian Febrifuge, +10 more Probable
What it is: Fever bark is the bark of the Australian tree Alstonia constricta, used in traditional medicine for fever, diarrhea, and infections.
Theoretically, fever bark might increase or decrease the effects of stimulant drugs.
Read the full Fever Bark + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGlucomannanGlucomanano, glucomannane, konjac, +1 more Probable
What it is: Glucomannan is a soluble fiber from the konjac root that swells into a gel in your stomach, which may help with mild weight loss, constipati...
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGoldensealHydrastis Canadensis, chinese Goldenseal, eye Balm, +14 more Probable
What it is: Goldenseal is a popular North American herb that contains berberine, a compound studied for antimicrobial effects.
Goldenseal might increase serum levels of drugs metabolized by CYP2D6.
Read the full Goldenseal + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGreen CoffeeCoffea Arabica, coffea Canephora, coffea Bukobensis, +2 more Probable
What it is: Green coffee is the unroasted bean of the coffee plant, prized for its high chlorogenic acid content.
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Green Coffee + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGreen TeaCamellia Sinensis, green Sencha Tea, green Tea Extract, +17 more Probable
What it is: Green tea is a popular beverage rich in antioxidants called catechins, and drinking it in normal amounts is considered safe for most people.
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Green Tea + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGuggulCommiphora Wightii, devadhupa, gomme Guggul, +17 more Probable
What it is: Guggul is a gum resin from the Commiphora wightii tree, long used in Ayurvedic medicine for cholesterol, joint, and skin problems.
Theoretically, guggul might reduce the effects of CYP3A4 substrates.
Read the full Guggul + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionIlex Guayusa Probable
What it is: Ilex guayusa is a caffeine-containing holly leaf from the Amazon, traditionally brewed as a tea for energy and alertness, much like yerba ma...
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Ilex Guayusa + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionKudzuPueraria Montana, bidarikand, bilaikanda, +18 more Probable
What it is: Kudzu is a fast-growing vine whose root has long been used in traditional Chinese medicine and is now studied mostly for reducing alcohol in...
Theoretically, taking kudzu with caffeine might increase levels of caffeine.
Read the full Kudzu + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionLithiumCarbonate De Lithium, citrate De Lithium, lithium Aspartate, +8 more Probable
What it is: Lithium is a naturally occurring metal that, in prescription form (lithium carbonate or citrate), is an FDA-approved, well-proven treatment...
Theoretically, taking lithium supplements with NSAIDs might increase lithium levels and adverse effects.
Read the full Lithium + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionMelatoninN-acetyl-5-methoxytryptamine Probable
What it is: Melatonin is a hormone your body makes naturally to help control your sleep-wake cycle, and the supplement form is widely used to help with...
Theoretically, melatonin might increase levels of drugs metabolized by CYP1A2.
Read the full Melatonin + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionOnionAllium Cepa, allii Cepae Bulbus, cebolla, +9 more Probable
What it is: Onion is a common food with a long history in traditional medicine, and it contains antioxidants like quercetin and sulfur compounds.
Concomitant use of aspirin with onion may worsen onion allergy.
Read the full Onion + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionOolong Tea Probable
What it is: Oolong tea is a traditional partially oxidized tea made from the same plant as green and black tea, and it provides caffeine and plant antio...
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Oolong Tea + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPanax GinsengAsian Ginseng, asiatic Ginseng, chinese Ginseng, +12 more Probable
What it is: Panax ginseng is a popular traditional herb used to boost energy, ease stress, and support overall wellness, though scientific evidence is m...
Theoretically, taking Panax ginseng with caffeine might increase the risk of adverse stimulant effects.
Read the full Panax Ginseng + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPsilocybin Probable
What it is: Psilocybin is a powerful psychedelic compound found in certain mushrooms and is being studied for hard-to-treat depression, anxiety, and add...
Theoretically, concomitant use of psilocybin with stimulant drugs might increase stimulant adverse effects.
Read the full Psilocybin + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPu-erh Tea Probable
What it is: Pu-erh tea is a fermented, aged form of tea made from the same plant as green and black tea.
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Pu-erh Tea + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSchisandraSchisandra Chinensis, bac Ngu Vi Tu, baie De Schisandra, +10 more Probable
What it is: Schisandra is a traditional Chinese medicine berry used as an adaptogen for stress, fatigue, and liver support.
Schisandra can increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Schisandra + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSodium Bicarbonate Probable
What it is: Sodium bicarbonate (baking soda) is a simple compound most often used as a fast-acting antacid and, in sports, as a buffer that may help wit...
Theoretically, sodium bicarbonate may reduce the levels and clinical effects of aspirin.
Read the full Sodium Bicarbonate + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSyrian Rue Probable
What it is: Syrian Rue (Peganum harmala) is a traditional plant whose seeds contain potent compounds called harmala alkaloids, including MAO-inhibiting...
Theoretically, Syrian rue might increase the levels and clinical effects of drugs metabolized by CYP2D6.
Read the full Syrian Rue + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionTree Turmeric Probable
What it is: Tree turmeric (Berberis aristata) is a shrub used in traditional Indian (Ayurvedic) medicine, valued mainly for its berberine content.
Theoretically, tree turmeric might increase the levels and clinical effects of drugs that are substrates of CYP3A4.
Read the full Tree Turmeric + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionWillow Bark Probable
What it is: Willow bark is a traditional plant remedy that contains salicin, a compound related to aspirin, and is most often used for pain and inflamma...
Theoretically, willow bark might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Willow Bark + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionWintergreen Probable
What it is: Wintergreen is a low-growing North American plant whose oil is rich in methyl salicylate, an aspirin-like compound used in topical pain rubs...
Using wintergreen oil topically in large amounts, with occlusive dressings, or for prolonged periods of time might increase the risk of additive salicylate toxicity when used with aspirin.
Read the full Wintergreen + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionYerba MansaAnemopsis Californica, anemopsis De Californie, lizard's Tail, +3 more Probable
What it is: Yerba mansa is a traditional Southwestern and Mexican medicinal plant used for sore throats, skin problems, and infections.
Theoretically, concomitant use might cause additive or prolonged sedative effects.
Read the full Yerba Mansa + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionYerba MateIlex Paraguariensis, chimarrao, green Mate, +14 more Probable
What it is: Yerba mate is a caffeine-containing herbal beverage from South America that is widely enjoyed for its stimulating, coffee-like effects.
Theoretically, concomitant use of stimulant drugs and yerba mate might increase stimulant adverse effects.
Read the full Yerba Mate + Aspirin, Caffeine, Dihydrocodeine Bitartrate interaction1,3-dmaaDmaa, dimethylamylamine Possible
What it is: DMAA (1,3-dimethylamylamine) is a synthetic stimulant that was sold in pre-workout and weight-loss supplements but has been linked to seriou...
1,3-DMAA strongly inhibits cytochrome P450 2D6 (CYP2D6) enzymes in vitro.
Read the full 1,3-dmaa + Aspirin, Caffeine, Dihydrocodeine Bitartrate interaction1,3-dmba Possible
What it is: 1,3-DMBA is a synthetic stimulant chemically similar to the banned stimulant DMAA, and it is not a proven or safe dietary ingredient.
Theoretically, combining 1,3-DMBA with other stimulant drugs might increase the risk of cardiovascular toxicity.
Read the full 1,3-dmba + Aspirin, Caffeine, Dihydrocodeine Bitartrate interaction1,4-dmaa Possible
What it is: 1,4-DMAA is a synthetic stimulant that the U.S.
1,4-DMAA is thought to have stimulant and vasoconstrictive effects, which have been demonstrated in animal studies.
Read the full 1,4-dmaa + Aspirin, Caffeine, Dihydrocodeine Bitartrate interaction5-htp5 Hydroxy-tryptophan, 5 Hydroxy-tryptophane, 5-hydroxytryptophan, +9 more Possible
What it is: 5-HTP is a compound your body uses to make serotonin, and people take it as a supplement hoping to improve mood, sleep, and headaches.
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAcacia RigidulaVachellia Rigidula, acacia Rigidula, acaciopsis Rigidula, +3 more Possible
What it is: Acacia rigidula is a shrub from Texas and Mexico that is marketed in weight-loss and energy supplements.
Theoretically, Acacia rigidula products that are adulterated with beta-methylphenylethylamine (BMPEA) might increase the levels of CYP2D6 substrates.
Read the full Acacia Rigidula + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAconiteAconitum Napellus, aconitum, aconitum Angustifolium, +20 more Possible
What it is: Aconite is a highly poisonous plant, and even small amounts of the raw or improperly processed root can cause severe, life-threatening react...
Theoretically, combining aconite with other antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
Read the full Aconite + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionActive Hexose Correlated Compound (ahcc) Possible
What it is: AHCC is a proprietary mushroom-derived supplement promoted mainly for immune support and to help people tolerate cancer treatment.
Theoretically, AHCC might increase levels of drugs metabolized by CYP2D6.
Read the full Active Hexose Correlated Compound (ahcc) + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAdrafinilAdrafinilum, benzhydryl Sulfinyl Acetyl Hydroxamic Acid, crl-40028, +1 more Possible
What it is: Adrafinil is a synthetic compound that the body converts into modafinil, a prescription wakefulness-promoting drug.
Theoretically, adrafinil might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Adrafinil + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAdrueCyperus Articulatus, chintul, cyperus, +5 more Possible
What it is: Adrue (Cyperus articulatus) is a sedge whose rhizome has long been used in traditional medicine for nausea and other stomach complaints, and...
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Adrue + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAfrican Wild Potato Possible
What it is: African Wild Potato (Hypoxis hemerocallidea) is a southern African plant traditionally used as a tonic and for immune, prostate, and inflamm...
In vitro evidence shows that African wild potato extract inhibits OAT3.
Read the full African Wild Potato + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAlbizia JulibrissinAlbizia Julibrissin, arbre De Sois, federbaum, +16 more Possible
What it is: Albizia julibrissin (Persian silk tree, He Huan) is a plant used in traditional Chinese medicine, mainly the flower and bark, for calming th...
Animal research suggests that certain constituents from Albizia julibrissin flowers can potentiate pentobarbital-induced sleeping time in mice.
Read the full Albizia Julibrissin + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAllspicePimenta Dioica, all Spice, allspice Essential Oil, +13 more Possible
What it is: Allspice is a popular cooking spice from a Caribbean evergreen tree that has long been used in folk medicine for digestion, pain, and infect...
Theoretically, combining allspice with an antiplatelet or anticoagulant drug might increase the risk of bleeding.
Read the full Allspice + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAloeAloe Vera, aloe Capensis, aloe Gel, +18 more Possible
What it is: Aloe vera gel is widely used on the skin for minor burns and irritation, and some research suggests it may help.
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAlpha-lipoic AcidThioctacid, thioctan, thioctic Acid Possible
What it is: Alpha-lipoic acid (ALA) is an antioxidant made naturally by the body and found in small amounts in foods.
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Alpha-lipoic Acid + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAmerican ElderSambucus Canadensis, american Elderberry, common Elderberry, +9 more Possible
What it is: American elder is a North American plant whose cooked, ripe berries and flowers are used mainly for colds, flu, and general immune support.
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full American Elder + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAndrographisAndrographis Paniculata, bhunimba, bidara, +19 more Possible
What it is: Andrographis is a bitter Asian herb traditionally used for colds, flu, and infections, and some studies suggest it may ease cold symptoms an...
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Andrographis + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAnisePimpinella Anisum, anis, anís, +14 more Possible
What it is: Anise is a fragrant, licorice-flavored seed used for centuries to ease digestion and soothe coughs.
Theoretically, anise oil might decrease the efficacy of caffeine.
Read the full Anise + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAristolochiaAristolochia Auricularia, birthwort, guan Mu Tong, +15 more Possible
What it is: Aristolochia contains aristolochic acid, a potent toxin linked to severe kidney damage and cancer, and it is not safe to take.
Aristolochia is nephrotoxic.
Read the full Aristolochia + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAsafoetidaFerula Assa-foetida, a Wei, asafétida, +13 more Possible
What it is: Asafoetida is a strong-smelling plant resin used widely as a spice and in traditional medicine, mainly for digestive complaints.
Theoretically, asafoetida might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Asafoetida + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAshitabaAngelica Keiskei, angelica, ashitaba Du Japon, +6 more Possible
What it is: Ashitaba is a leafy plant from Japan that is eaten as a vegetable and taken as a supplement for general health, antioxidant, and heart benef...
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Ashitaba + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAshwagandhaWithania Somnifera, ajagandha, amangura, +17 more Possible
What it is: Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, thoug...
Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Read the full Ashwagandha + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspenPopulus Tremuloides, populus Tremula, Álamo Temblón, +8 more Possible
What it is: Aspen bark and leaf contain salicin, a natural compound related to aspirin, which is why it is traditionally used for pain, fever, and infla...
Aspen contains salicin, a plant salicylate.
Read the full Aspen + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAstaxanthinAstaxanthine, astaxantina, dihydroxy-3, +6 more Possible
What it is: Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and...
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAtractylodesAtractylodes Lancea, amk, atr, +9 more Possible
What it is: Atractylodes is a root used for centuries in traditional Chinese, Japanese, and Thai medicine, mostly for digestive complaints and fatigue,...
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylodes + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBabassuAttalea Speciosa, babaçu, babassou, +5 more Possible
What it is: Babassu comes from a Brazilian palm tree, and its oil and mesocarp flour are used in foods, cosmetics, and traditional remedies.
Evidence from animal research suggests that babassu has antithrombotic effects.
Read the full Babassu + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBacopaBacopa Monnieri, andri, brahmi, +11 more Possible
What it is: Bacopa is an Ayurvedic herb most often used for memory and thinking.
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBaikal SkullcapScutellaria Baicalensis, baikal Scullcap, baikal Skullcap Root, +16 more Possible
What it is: Baikal skullcap is a traditional Chinese herb (Huang Qin) used for inflammation, allergies, and infections, with active compounds like baica...
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Baikal Skullcap + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBanderolOtoba Parvifolia Possible
What it is: Banderol is a Nutramedix-branded herbal extract made from the bark of the Amazonian tree Otoba parvifolia, most often promoted as part of al...
Small lab studies have found that Banderol may also inhibit OATP1B3 (Organic Anion Transporting Polypeptide 1B3), in addition to OATP1B1.
Read the full Banderol + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBasilOcimum Basilicum, albahaca, basilic, +15 more Possible
What it is: Basil is a popular cooking herb that is generally safe in the amounts used in food.
Theoretically, basil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Basil + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBay LeafLaurus Nobilis, bay, bay Laurel, +17 more Possible
What it is: Bay leaf is a common culinary herb that is safe in the small amounts used in cooking.
Theoretically, taking bay leaf in large amounts may enhance the therapeutic and adverse effects of sedatives.
Read the full Bay Leaf + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBear's GarlicAllium Ursinum, ail Des Bois, ail à Feuilles Larges, +11 more Possible
What it is: Bear's garlic is a wild relative of garlic enjoyed mainly as a mild-tasting food.
In vitro research shows that bear's garlic and some of its constituents can inhibit platelet aggregation.
Read the full Bear's Garlic + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBeetBeta Vulgaris, beet Greens, beet Juice, +19 more Possible
What it is: Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in...
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBerberineAlcaloïde De Berbérine, berberina, berbérine, +5 more Possible
What it is: Berberine is a yellow plant compound that has shown promise for lowering blood sugar and cholesterol in some studies, but the quality of res...
Theoretically, berberine might increase the sedative effects of CNS depressants.
Read the full Berberine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBeta-methylphenethylamine (bmpea) Possible
What it is: Beta-methylphenethylamine (BMPEA) is a synthetic stimulant chemically similar to amphetamine that has been found in some weight-loss and spo...
Theoretically, BMPEA might increase the levels and clinical effects of CYP2D6 substrates.
Read the full Beta-methylphenethylamine (bmpea) + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBilberryVaccinium Myrtillus, airelle, arándano, +16 more Possible
What it is: Bilberry is a blueberry-like fruit rich in antioxidant plant compounds called anthocyanins, and it has a long history of traditional use for...
Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Bilberry + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBiofeedback Possible
What it is: Biofeedback is a mind-body technique, not an herb or supplement.
There is some concern that electroencephalogram (EEG) biofeedback might lower the seizure threshold in some patients.
Read the full Biofeedback + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBishop's WeedAmmi Majus, Élevé, ammi Inodore, +12 more Possible
What it is: Bishop's Weed (Ammi majus) is a flowering plant whose seeds contain natural light-sensitizing compounds called psoralens, which have been st...
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Bishop's Weed + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBismuth Possible
What it is: Bismuth is a metallic element used in medicine mostly as bismuth subsalicylate (the active ingredient in some well-known stomach remedies) t...
Theoretically, use of bismuth subgallate or other bismuth salts might reduce the effects of anticoagulant/antiplatelet drugs.
Read the full Bismuth + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBitter AlmondPrunus Amygdalus, almendra Amarga, almendro Amargo, +13 more Possible
What it is: Bitter almond is a variety of almond that contains amygdalin, a compound the body converts into cyanide, making it potentially poisonous.
Theoretically, bitter almond oil may have additive effects with other CNS depressants.
Read the full Bitter Almond + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBitter OrangeCitrus Aurantium, aurantii Fructus, aurantium, +17 more Possible
What it is: Bitter orange is a citrus fruit whose extracts contain synephrine, a mild stimulant often added to weight-loss and energy supplements.
Bitter orange might increase levels of drugs metabolized by CYP3A4.
Read the full Bitter Orange + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBlack CohoshActaea Racemosa, baie D'actée, baneberry, +10 more Possible
What it is: Black cohosh is a North American plant most often used to ease menopause symptoms like hot flashes, but the research is mixed and far from s...
Some research suggests that black cohosh might inhibit CYP2D6, but there is conflicting evidence.
Read the full Black Cohosh + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBlack CurrantRibes Nigrum, black Currant Seed Oil, cassis, +8 more Possible
What it is: Black currant is a nutritious berry that is rich in vitamin C and antioxidants, and its seed oil contains the omega-6 fatty acid GLA.
Theoretically, black currant seed oil might increase the risk of bleeding if used in combination with anticoagulant or antiplatelet drugs.
Read the full Black Currant + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBlack Hoof MushroomPhellinus Linteus, black Hoof Fungus, mesima, +5 more Possible
What it is: Black Hoof Mushroom (Phellinus linteus) is a medicinal mushroom long used in East Asian traditional medicine, mainly for immune support.
Theoretically, black hoof mushroom might increase the levels and clinical effects of CYP1A2 substrates.
Read the full Black Hoof Mushroom + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBlack PepperPiper Nigrum, black Peppercorn, extrait De Poivre, +23 more Possible
What it is: Black pepper is a common kitchen spice that is generally safe in the amounts used in food.
Theoretically, black pepper might increase levels of drugs metabolized by CYP2D6.
Read the full Black Pepper + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBlack SeedNigella Sativa, black Caraway, black Cumin, +18 more Possible
What it is: Black seed (Nigella sativa) is a traditional spice and remedy that has been studied for asthma, blood sugar, cholesterol, and blood pressure...
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Black Seed + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBlood Irradiation Therapy Possible
What it is: Blood Irradiation Therapy is a medical procedure—not a dietary supplement or herb—in which blood is exposed to ultraviolet or laser light, e...
Preliminary clinical research suggests that blood irradiation therapy might reduce platelet aggregation.
Read the full Blood Irradiation Therapy + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBog Labrador TeaRhododendron Groenlandicum, bog Tea, continental Tea, +12 more Possible
What it is: Bog Labrador tea is a wetland shrub whose leaves have long been brewed as a traditional beverage and folk remedy, especially among Indigenou...
In vitro research shows that aqueous and ethanolic extracts of Bog Labrador tea leaves can increase the concentration of cytochrome P450 3A4 (CYP3A4) enzymes.
Read the full Bog Labrador Tea + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBoldoPeumus Boldus, boldine, boldo Folium, +4 more Possible
What it is: Boldo is a South American shrub whose leaves are traditionally used for digestive and gallbladder complaints, but good human evidence is ver...
Theoretically, taking boldo with anticoagulant/antiplatelet drugs might increase the risk of bleeding.
Read the full Boldo + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBorageBee Plant, beebread, borage Oil, +12 more Possible
What it is: Borage is a Mediterranean herb whose seed oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid studied mostly for skin condition...
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBoswellia SerrataBoswellia Serrata, arbre à Oliban Indien, boswella, +10 more Possible
What it is: Boswellia serrata is a tree resin used in traditional medicine, mainly for joint pain and inflammation.
Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
Read the full Boswellia Serrata + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBreadfruit Possible
What it is: Breadfruit is a starchy tropical fruit eaten as a staple food, and its leaves are used in traditional medicine for conditions like high bloo...
Theoretically, concomitant use with anticoagulant/antiplatelet drugs might increase the risk of bleeding.
Read the full Breadfruit + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBroccoli Possible
What it is: Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific int...
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBromelain Possible
What it is: Bromelain is a group of protein-digesting enzymes from pineapple that people take mainly for inflammation, swelling, and sinus problems.
Bromelain may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Bromelain + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBrussels Sprout Possible
What it is: Brussels sprouts are a nutritious cruciferous vegetable rich in fiber, vitamin C, vitamin K, and plant compounds called glucosinolates.
Animal research suggests that Brussels sprout can induce cytochrome P450 1A2 (CYP1A2) activity.
Read the full Brussels Sprout + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBuchuAgathosma Betulina, anysboegoe, barasmae Folium, +12 more Possible
What it is: Buchu is a fragrant South African shrub whose leaves are traditionally used for urinary and bladder complaints and as a diuretic.
Buchu may have antiplatelet effects.
Read the full Buchu + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBulbine Natalensis Possible
What it is: Bulbine natalensis is a South African plant marketed mainly as a testosterone-boosting and libido supplement, but the human evidence is esse...
Theoretically, Bulbine natalensis stem might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Bulbine Natalensis + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBupleurumBei Chai Hu, bupleuri, bupleurum Chinese, +12 more Possible
What it is: Bupleurum (Chai Hu) is a root used in traditional Chinese medicine, usually as part of multi-herb formulas, for liver, digestive, and fever-...
Theoretically, bupleurum might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Bupleurum + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBurdockArctium Lappa, arctium, bardana, +20 more Possible
What it is: Burdock is a traditional herb most often used for skin problems and as a so-called 'blood purifier,' but high-quality human studies are lack...
Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Burdock + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCabbageBrassica Oleracea, cabbage Leaf, chou, +13 more Possible
What it is: Cabbage is a nutritious, low-calorie vegetable that is safe to eat as food and is sometimes applied to the skin as a leaf wrap for breast en...
Theoretically, cabbage might decrease levels of drugs metabolized by CYP1A2.
Read the full Cabbage + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCaffeic Acid Possible
What it is: Caffeic acid is a natural plant compound found in coffee, many fruits, vegetables, and herbs, and it is studied mainly for its antioxidant a...
Theoretically, caffeic acid might increase the levels and clinical effects of OAT3 substrates.
Read the full Caffeic Acid + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCajeput OilMelaleuca Leucadendra, aceite De Cajeput, cajeputi Aetheroleum, +10 more Possible
What it is: Cajeput oil is an aromatic essential oil traditionally used for aches, congestion, and minor skin complaints, but solid human evidence for t...
Evidence from in vitro research suggests that cajeput leaf extract can inhibit cytochrome P450 2D6 (CYP2D6) by approximately 30%.
Read the full Cajeput Oil + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCalamusAcorus Calamus, acore Calame, acore Odorant, +20 more Possible
What it is: Calamus is a swamp plant with a long history in Ayurvedic and traditional Chinese medicine, mostly for digestive and nervous-system complain...
Theoretically, concurrent use of CNS depressants and calamus might have an additive effect and increase the risk of sedative effects.
Read the full Calamus + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCalifornia PoppyEschscholzia Californica, amapola De California, pavot D'amérique, +4 more Possible
What it is: California poppy is a traditional herbal remedy used mainly for anxiety and sleep problems, often combined with other calming herbs.
Theoretically, taking California poppy with drugs with sedative effects may increase the risk of sedative effects.
Read the full California Poppy + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCanadian Fleabane Possible
What it is: Canadian Fleabane is a common North American weed used in traditional medicine for diarrhea, minor bleeding, and urinary issues, but high-qu...
Theoretically, Canadian fleabane might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Canadian Fleabane + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCannabichromene (cbc)Cannabichrome, pentylcannabichromene, cannabinochromene Possible
What it is: Cannabichromene (CBC) is a non-intoxicating cannabinoid found in the cannabis plant that is being studied for possible pain, anti-inflammato...
Using cannabichromene with drugs that have sedative properties may cause additive therapeutic and adverse effects.
Read the full Cannabichromene (cbc) + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCannabisCannabis Sativa, anashca, banji, +25 more Possible
What it is: Cannabis contains many active compounds, mainly THC (which causes a 'high') and CBD (which does not).
Theoretically, cannabis might have additive effects if used with other CNS depressants.
Read the full Cannabis + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCaprylic AcidOctanoic Acid Possible
What it is: Caprylic acid is a medium-chain fatty acid found in coconut oil and palm kernel oil that is popularly used for yeast overgrowth and gut heal...
Theoretically, caprylic acid might increase plasma concentrations of NSAIDs.
Read the full Caprylic Acid + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCapsicum Possible
What it is: Capsicum (chili pepper) contains capsaicin, which is best known and best studied as a topical treatment for certain types of pain.
Theoretically, capsicum may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Capsicum + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCarawayCarum Carvi, alcaravea, anis Canadien, +20 more Possible
What it is: Caraway is a common cooking spice that has long been used to ease gas, bloating, and indigestion.
Theoretically, caraway might increase the effects and adverse effects of CNS depressants.
Read the full Caraway + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCarrageenan Possible
What it is: Carrageenan is a fiber-like substance taken from red seaweed and is mostly used as a thickener and gelling agent in foods.
Theoretically, carrageenan may increase the risk of bleeding in patients taking anticoagulant or antiplatelet drugs.
Read the full Carrageenan + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCat's ClawGriffe Du Chat, hawk's Claw, liane Du Pérou, +4 more Possible
What it is: Cat's claw is a South American vine traditionally used for inflammation, joint pain, and immune support.
Theoretically, cat's claw might increase or decrease the levels and effects of drugs metabolized by CYP3A4.
Read the full Cat's Claw + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCatechuBlack Catechu, acacia Catechu: Acacia à Cachou, acacia Catechu Heartwood Extract, +17 more Possible
What it is: Catechu is an astringent extract made from the heartwood of the Acacia (Senegalia) catechu tree, used traditionally for mouth sores, sore th...
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCatnipNepeta Cataria, cataire, catmint, +8 more Possible
What it is: Catnip is a mint-family herb most often used as a calming tea for sleep, anxiety, and minor digestive upset, but solid human research suppor...
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCauliflower Possible
What it is: Cauliflower is a nutritious cruciferous vegetable that provides vitamin C, fiber, and plant compounds called glucosinolates.
Preliminary clinical evidence suggests that eating cruciferous vegetables, including broccoli, cauliflower, daikon radish sprouts, and cabbage, can increase cytochrome P450 1A2 (CYP1A2) activity by 14% to 27%.
Read the full Cauliflower + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCeleryApium Graveolens, ache Des Marais, ajamoda, +13 more Possible
What it is: Celery is a common vegetable that is also taken as a seed extract or oil supplement, mainly for blood pressure, fluid retention, and joint d...
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCeylon Leadwort Possible
What it is: Ceylon Leadwort (Plumbago zeylanica) is a plant long used in Ayurvedic and other traditional medicine systems, mainly for digestion, skin pr...
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 2D6 (CYP2D6) in vitro.
Read the full Ceylon Leadwort + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionChaga Possible
What it is: Chaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support.
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionChanca PiedraPhyllanthus Niruri, amli, arranca-pedras, +16 more Possible
What it is: Chanca piedra is a tropical herb traditionally used as a 'stone breaker' for kidney and gallstones, and for liver and urinary health.
Theoretically, chanca piedra might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Chanca Piedra + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionChokeberryAronia Arbutifolia, aronia Melanocarpa, aronia Nigra, +1 more Possible
What it is: Chokeberry (aronia) is a dark berry rich in antioxidants called polyphenols, and it's widely eaten as juice, jam, and supplements.
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Chokeberry + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionChrysin Possible
What it is: Chrysin is a plant flavonoid sold mainly as a bodybuilding supplement claimed to raise testosterone or block estrogen, but human studies hav...
Theoretically, chrysin might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Chrysin + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCilantro Possible
What it is: Cilantro is the leafy part of the Coriandrum sativum plant and is widely eaten as a food, where it is considered safe for most people.
In vitro research suggests that extracts of cilantro can inhibit platelet aggregation.
Read the full Cilantro + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCinchonaCinchona Calisaya, arbol De La Quina, bois Aux Fièvres, +14 more Possible
What it is: Cinchona bark is the natural source of quinine and has been used for centuries to treat malaria and fever, but the bark itself is not standa...
Theoretically, taking cinchona might inhibit cytochrome P450 2D6 (CYP2D6) and increase levels of drugs metabolized by this enzyme.
Read the full Cinchona + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCloveSyzygium Aromaticum, bourgeon Floral De Clou De Girofle, bouton Floral De Clou De Girofle, +12 more Possible
What it is: Clove is a common cooking spice that is also used in traditional medicine, especially as a topical numbing agent for tooth pain thanks to it...
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP2D6.
Read the full Clove + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCnidiumCnidium Monnieri, cnidii Fructus, cnidii Monnieri Fructus, +10 more Possible
What it is: Cnidium is the dried fruit of an Asian plant long used in traditional Chinese medicine, mostly for skin problems and sexual health.
In laboratory research, cnidium has been shown to have sedative and hypnotic effects, possibly related to constituent coumarins.
Read the full Cnidium + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCod Liver Oil Possible
What it is: Cod liver oil supplies omega-3 fatty acids (EPA and DHA) along with vitamins A and D, and is popular for heart, joint, and general health su...
Theoretically, cod liver oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Cod Liver Oil + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCodonopsis Possible
What it is: Codonopsis (often called 'dang shen') is a root long used in Traditional Chinese Medicine as a gentle energy and digestive tonic, frequently...
Theoretically, codonopsis liquor might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Codonopsis + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionColeus6beta, 17beta-acetoxy-8, 13-epoxy-1alpha, +15 more Possible
What it is: Coleus is a plant from the mint family whose root contains a compound called forskolin, often marketed for weight loss, asthma, and heart he...
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionColtsfootTussilago Farfara, ass's Foot, brandlattich, +17 more Possible
What it is: Coltsfoot is a traditional herb long used to soothe coughs and clear mucus, but solid human evidence for these uses is lacking.
Concomitant use might increase the risk of bleeding due to decreased platelet aggregation.
Read the full Coltsfoot + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionConjugated Linoleic Acid (cla) Possible
What it is: CLA is a fatty acid found naturally in meat and dairy, and supplements are usually made from safflower oil.
Theoretically, CLA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Conjugated Linoleic Acid (cla) + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCordycepsOphiocordyceps Sinensis, caterpillar Fungus, caterpillar Mushroom, +10 more Possible
What it is: Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support.
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCorianderCoriandrum Sativum, coriander Essential Oil, coriandre, +5 more Possible
What it is: Coriander (also called cilantro) is a common cooking herb and spice that has long been used in traditional medicine for digestive complaints...
Theoretically, coriander might cause additive sedative effects when taken with CNS depressants.
Read the full Coriander + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCorn PoppyPapaver Rhoeas, amapola, common Poppy, +18 more Possible
What it is: Corn poppy is a red-flowered plant traditionally used in teas and syrups for cough, sleep, and mild pain.
Theoretically, concomitant use of corn poppy with CNS depressants might increase the risk of sedation.
Read the full Corn Poppy + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCorydalis Yanhusuo Possible
What it is: Corydalis yanhusuo is a traditional Chinese herb used mainly for pain.
Theoretically, Corydalis yanhusuo might increase the sedative effects of CNS depressants.
Read the full Corydalis Yanhusuo + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCranberryVaccinium Macrocarpon, agrio, american Cranberry, +16 more Possible
What it is: Cranberry is best known for helping to prevent repeated urinary tract infections (UTIs) in some people, and the evidence here is moderate bu...
Theoretically, cranberry might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Cranberry + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCubebsPiper Cubeba, cubeb, cubeb Berries, +14 more Possible
What it is: Cubebs are spicy, peppery berries from a vine in the pepper family that have long been used in traditional medicine for coughs, digestion, a...
Several compounds isolated from cubebs can inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Cubebs + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCuminCuminum Cyminum, anis Âcre, comino, +6 more Possible
What it is: Cumin is a common cooking spice that has a long history in traditional medicine for digestion and other complaints.
Theoretically, cumin might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cumin + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCypress Possible
What it is: Cypress comes from the Mediterranean cypress tree and is most often used as an essential oil in aromatherapy or skin care, and traditionally...
In vitro evidence shows that cypress cone extract inhibits blood coagulation in a concentration-dependent manner.
Read the full Cypress + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionDandelionTaraxacum Officinale, blowball, cankerwort, +17 more Possible
What it is: Dandelion is a common plant used in food and traditional medicine, often promoted as a natural 'water pill' and digestive aid.
Theoretically, dandelion might increase levels of drugs metabolized by CYP1A2.
Read the full Dandelion + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionDelta-9-tetrahydrocannabinol (thc)Bho, black Glass, budder, +9 more Possible
What it is: THC is the main mind-altering compound in cannabis and is best known for causing a 'high.' A prescription form (dronabinol) is approved for...
Theoretically, THC might have additive effects if used with other CNS depressants.
Read the full Delta-9-tetrahydrocannabinol (thc) + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionDendrobium Possible
What it is: Dendrobium is a group of orchids long used in traditional Chinese medicine, often to moisten the body and as a general tonic.
The dendrobium constituent dendrobine is reported to have convulsant effects.
Read the full Dendrobium + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionDevil's ClawHarpagophytum Procumbens, devils Claw, devil's Claw Root, +9 more Possible
What it is: Devil's claw is a southern African plant used mainly for arthritis and back pain, and some studies suggest it may help ease these types of d...
Theoretically, devil's claw might increase levels of drugs metabolized by CYP3A4.
Read the full Devil's Claw + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionDhea3b-hydroxy-androst-5-ene-17-one, 3betahydroxy-androst-5-ene-17-one, androstenolone, +4 more Possible
What it is: DHEA is a natural hormone that the body makes and that declines with age, and it is sold as a supplement claiming many benefits.
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dhea + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionDimethylhexylamine (dmha) Possible
What it is: DMHA (dimethylhexylamine, also called octodrine) is a synthetic stimulant added to some pre-workout and weight-loss supplements, often false...
Theoretically, combining DMHA with stimulant drugs might increase the risk of adverse cardiovascular effects.
Read the full Dimethylhexylamine (dmha) + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionDimethylsulfoxide (dmso)Dimethyl Sulfoxide, dimethyl Sulphoxide, dimethylis Sulfoxidum Possible
What it is: DMSO is a colorless liquid solvent that people apply to the skin for pain and inflammation, and it is FDA-approved (as a prescription) only...
Theoretically, DMSO might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Dimethylsulfoxide (dmso) + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionDiosmin Possible
What it is: Diosmin is a citrus-derived flavonoid most often used for vein-related problems such as chronic venous insufficiency and hemorrhoids, and it...
Theoretically, diosmin might inhibit the metabolism of CYP3A4 substrates.
Read the full Diosmin + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionDong QuaiAngelica Sinensis, angelica China, chinese Angelica, +15 more Possible
What it is: Dong Quai is a traditional Chinese herb often called "female ginseng" and is mostly used for menstrual and menopausal complaints.
Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Dong Quai + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionDyer's BroomGenista Tinctoria, broom Flower, dyers Broom, +16 more Possible
What it is: Dyer's broom is a European flowering plant best known historically as a source of yellow textile dye, with some traditional medicinal uses.
Theoretically, dyer's broom might reduce the clearance of caffeine.
Read the full Dyer's Broom + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionEicosapentaenoic Acid (epa) Possible
What it is: EPA is an omega-3 fatty acid found mostly in fatty fish and fish oil, and it is best known for lowering high triglycerides.
Theoretically, EPA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Eicosapentaenoic Acid (epa) + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionElecampaneAlant, aunée, aunée Officinale, +17 more Possible
What it is: Elecampane is a traditional herb used mainly for coughs and other respiratory complaints, and as a bitter for digestion.
Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Read the full Elecampane + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionEleutheroEleutherococcus Senticosus, acanthopanax Obovatus, ciwujia Root, +13 more Possible
What it is: Eleuthero is an herb traditionally used as an 'adaptogen' to fight fatigue, boost energy, and help the body handle stress.
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleuthero + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionEnglish IvyHedera Helix, common Ivy, gum Ivy, +9 more Possible
What it is: English ivy leaf extract is most commonly used in cough and cold syrups to help loosen mucus and ease coughing, and it is a popular ingredie...
Theoretically, English ivy might increase the levels of drugs metabolized by CYP2D6.
Read the full English Ivy + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionErgotClaviceps Purpurea, cockspur Rye, cornezuelo, +7 more Possible
What it is: Ergot is a toxic fungus that grows on rye and contains powerful chemicals (ergot alkaloids) that strongly narrow blood vessels and squeeze t...
Co-administration of stimulant drugs with ergot may increase the risk of vasoconstriction.
Read the full Ergot + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionEucalyptusEucalyptus Globulus, blue Gum, blue Mallee, +13 more Possible
What it is: Eucalyptus is best known for its strong-smelling oil used in vapor rubs, inhalants, and lozenges to ease coughs and congestion.
Theoretically, eucalyptus might increase the levels of CYP1A2 substrates.
Read the full Eucalyptus + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionEuropean BarberryBerberis Vulgaris, agracejo, barberry, +15 more Possible
What it is: European barberry is a shrub whose root, bark, and berries contain berberine, a bitter plant alkaloid that has been studied mostly in isolat...
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full European Barberry + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionEvening PrimroseOenothera Biennis, oenothera Muricata, oenothera Rubricaulis, +3 more Possible
What it is: Evening primrose oil is a seed oil rich in gamma-linolenic acid (GLA), an omega-6 fatty acid, that is popularly used for skin conditions, PM...
Theoretically, evening primrose oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Evening Primrose + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionFalse UnicornChamaelirium Luteum, alétris, blazing Star, +9 more Possible
What it is: False Unicorn is a North American plant whose root has long been used in traditional medicine for women's reproductive and menstrual concern...
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Read the full False Unicorn + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionFasting Possible
What it is: Fasting means voluntarily going without food (and sometimes drink) for set periods.
Fasting may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fasting + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionFennelFoeniculum Vulgare, adas, almindelig Fennikel, +20 more Possible
What it is: Fennel is a Mediterranean herb widely used as a food and spice, and traditionally taken for digestive complaints, colic, and menstrual cramp...
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionFeverfewTanacetum Parthenium, altamisa, bachelor's Buttons, +13 more Possible
What it is: Feverfew is a daisy-family herb best known for migraine prevention, where some studies suggest it may modestly lower how often migraines occ...
Theoretically, feverfew might increase levels of drugs metabolized by CYP2D6.
Read the full Feverfew + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionFlaxseedLinum Usitatissimum, alasi, aliviraaii, +20 more Possible
What it is: Flaxseed is a nutritious food rich in fiber, omega-3 fats (ALA), and plant compounds called lignans.
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionFlaxseed Oil Possible
What it is: Flaxseed oil is a plant-based source of the omega-3 fatty acid ALA, which the body can partly convert to the omega-3s found in fish oil.
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Oil + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionFo-ti Possible
What it is: Fo-ti (He Shou Wu) is a root used in traditional Chinese medicine, often promoted for healthy aging and hair.
Theoretically, fo-ti may increase the levels and clinical effects of drugs metabolized by CYP2D6.
Read the full Fo-ti + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionFulvic Acid Possible
What it is: Fulvic acid is a natural compound formed when plants and microbes break down in soil, and it is sold as a supplement for energy, gut, and ov...
Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
Read the full Fulvic Acid + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGalphimia GlaucaGalphimia Glauca, calderona Amarilla, flor Estrella, +2 more Possible
What it is: Galphimia glauca is a shrub from Mexico and Central America that has been studied mainly for anxiety, with some small clinical trials sugges...
Theoretically, taking Galphimia glauca with CNS depressants may increase the risk of sedation.
Read the full Galphimia Glauca + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGamma Butyrolactone (gbl)2-3 Dihydro Furanone Possible
What it is: Gamma butyrolactone (GBL) is a toxic industrial solvent, not a dietary supplement, and the body converts it into GHB, a powerful and dangero...
Theoretically, concomitant use of GBL with CNS depressants may potentiate respiratory and CNS depression.
Read the full Gamma Butyrolactone (gbl) + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGamma-linolenic Acid (gla) Possible
What it is: Gamma-linolenic acid (GLA) is an omega-6 fatty acid found in oils like evening primrose and borage.
Theoretically, GLA might increase the risk of bleeding when taken with anticoagulant or antiplatelet rugs.
Read the full Gamma-linolenic Acid (gla) + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGarciniaGarcinia Gummi-gutta, acide Hydroxycitrique, ahc, +11 more Possible
What it is: Garcinia is a tropical fruit whose rind contains hydroxycitric acid (HCA), widely marketed for weight loss and appetite control.
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGarden CressLepidium Sativum, berro Hortelano, cresson Alénois, +3 more Possible
What it is: Garden cress is a nutritious leafy herb and seed used widely in cooking and traditional medicine, providing vitamins, minerals, and fiber.
Theoretically, garden cress seed may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Garden Cress + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGarlicAllium Sativum, aged Black Garlic Extract, aged Garlic Extract, +16 more Possible
What it is: Garlic is a common food and supplement that may modestly help with blood pressure and cholesterol, though the evidence is mixed and effects...
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.
Read the full Garlic + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGenistein Combined Polysaccharide Possible
What it is: Genistein Combined Polysaccharide (GCP) is a soy-and-mushroom supplement studied mostly for hormone-related cancers like prostate cancer, bu...
Theoretically, genistein combined polysaccharide might reduce the clearance of caffeine.
Read the full Genistein Combined Polysaccharide + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGerman ChamomileMatricaria Recutita, blue Chamomile, camomèle, +12 more Possible
What it is: German chamomile is a widely used herbal remedy taken mainly as a tea for calming, sleep, and digestive complaints.
Theoretically, German chamomile might have additive effects when used with CNS depressants.
Read the full German Chamomile + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGingerZingiber Officinale, african Ginger, ardraka, +21 more Possible
What it is: Ginger is a widely used culinary spice with a long history in traditional medicine, and it has the strongest evidence for helping with nause...
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGinkgoGinkgo Biloba, abricot Argenté Japonais, adiantifolia, +13 more Possible
What it is: Ginkgo is one of the world's most popular herbal supplements, mostly taken to support memory and circulation.
Theoretically, taking ginkgo with drugs that lower the seizure threshold might increase the risk for convulsions.
Read the full Ginkgo + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGoat's RueGalega Officinalis Possible
What it is: Goat's rue is a traditional herb most often used by nursing parents to try to increase milk supply, and it has a historical link to diabetes...
Laboratory research suggests that goat's rue extract can inhibit platelet aggregation.
Read the full Goat's Rue + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGojiLycium Chinense, lycium Barbarum, barberry Matrimony Vine, +15 more Possible
What it is: Goji berries are a nutritious fruit rich in antioxidants, vitamins, and plant polysaccharides, and they are safe for most people as a food.
Theoretically, goji berry might inhibit CYP2D6 and reduce metabolism of CYP2D6 substrates.
Read the full Goji + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGoldthreadCoptis Chinensis, cankerroot, chinese Coptis, +13 more Possible
What it is: Goldthread is a traditional Chinese and East Asian herb whose root is rich in berberine, a compound being studied for blood sugar, cholester...
There's very preliminary evidence that berberine, a constituent of goldthread, might inhibit cytochrome P450 3A4 (CYP3A4) enzyme.
Read the full Goldthread + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGotu KolaCentella Asiatica, asiatic Pennywort, brahma-buti, +12 more Possible
What it is: Gotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memor...
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Gotu Kola + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGrapeVitis Vinifera, activin, black Grape Raisins, +10 more Possible
What it is: Grapes and grape products like grape seed extract contain antioxidant compounds such as resveratrol and proanthocyanidins that may support h...
Theoretically, grape seed extract may increase the levels of CYP2D6 substrates.
Read the full Grape + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGreater CelandineChelidonium Majus, bai Qu Cai, celandine, +9 more Possible
What it is: Greater celandine is a traditional herb most often promoted for digestive and gallbladder complaints, but solid human evidence for any use i...
Research in vitro shows that chelidonine, a constituent of greater celandine, inhibits cytochrome P450 2D6 (CYP2D6) enzyme activity.
Read the full Greater Celandine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGriffonia SimplicifoliaBandeiraea Simplicifolia Possible
What it is: Griffonia simplicifolia is a West African shrub whose seeds are a natural source of 5-HTP, a building block of the brain chemical serotonin.
Theoretically, taking Griffonia simplicifolia seed extract with CNS depressants might increase the risk of additive CNS depression.
Read the full Griffonia Simplicifolia + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGuar GumDietary Fiber, farine De Guar, fibre Alimentaire, +10 more Possible
What it is: Guar gum is a soluble, gel-forming fiber from the guar bean that may modestly help with cholesterol, blood sugar, and bowel regularity.
Guar gum might reduce the absorption of some oral drugs, potentially decreasing their effectiveness.
Read the full Guar Gum + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGuaranaPaullinia Cupana, brazilian Cocoa, cacao Brésilien, +3 more Possible
What it is: Guarana is an Amazonian seed that is naturally high in caffeine, which explains most of its stimulant and energy effects.
Theoretically, guarana may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Guarana + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGuarumoCecropia Obtusifolia, chancarro, grayumbo, +9 more Possible
What it is: Guarumo (Cecropia obtusifolia) is a tropical tree used in Latin American traditional medicine, most often as a leaf tea for diabetes and hig...
In an animal study, an aqueous extract of guarumo depressed the central nervous system, inducing significant motor incoordination and muscle relaxant activity.
Read the full Guarumo + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGum ArabicAcacia, acacia Gum, arabic Gum, +16 more Possible
What it is: Gum arabic is a soluble dietary fiber from the acacia tree that is widely used as a safe food additive and is sometimes taken as a supplemen...
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Gum Arabic + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGymnemaGymnema Sylvestre, gimnema, gur-mar, +14 more Possible
What it is: Gymnema is an Ayurvedic herb best known for possibly helping lower blood sugar and reducing the taste of sweetness on the tongue.
Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Read the full Gymnema + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionHawthornAubepine, aubépine, aubépine Blanche, +15 more Possible
What it is: Hawthorn is a plant traditionally used for heart-related complaints, and some studies suggest it may modestly help symptoms of mild heart fa...
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionHesperidinAlpha-glucosyl Hesperidin, alpha-glucosylhesperidin, bioflavonoid, +8 more Possible
What it is: Hesperidin is a flavonoid found in citrus fruits that is often combined with diosmin and used for vein and circulation problems like hemorrh...
Theoretically, concomitant use with CNS depressants may cause additive sedative effects.
Read the full Hesperidin + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionHigenamine Possible
What it is: Higenamine is a plant-based stimulant compound added to many weight-loss and pre-workout supplements, but there is very little human evidenc...
Theoretically, higenamine might increase the levels and clinical effects of drugs metabolized by CYP2D6.
Read the full Higenamine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionHoly BasilOcimum Tenuiflorum, ocimum Sanctum Possible
What it is: Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly s...
Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Holy Basil + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionHoneysuckle Possible
What it is: Honeysuckle, especially Japanese honeysuckle flower (Lonicera japonica), is a staple of traditional Chinese medicine used mainly for colds,...
Theoretically, honeysuckle might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Honeysuckle + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionHopsHumulus Lupulus, asperge Sauvage, common Hops, +13 more Possible
What it is: Hops are most often used for sleep and mild anxiety, frequently combined with valerian, but the human evidence is limited and not very stron...
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Read the full Hops + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionHordenineAnhalinine Possible
What it is: Hordenine is a natural alkaloid found in barley and some cacti that is marketed as a stimulant for energy, focus, and fat loss, but solid hu...
Hordenine is structurally similar to N-methyltyramine and synephrine, constituents in bitter orange known to have stimulant properties.
Read the full Hordenine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionHorny Goat WeedEpimedium Grandiflorum, barrenwort, Épimède, +10 more Possible
What it is: Horny goat weed (Epimedium) is a traditional Chinese herb most often marketed for low libido and erectile problems, but solid human evidence...
Theoretically, horny goat weed might increase the effects and side effects of CYP1A2 substrates.
Read the full Horny Goat Weed + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionHorse Chestnut Possible
What it is: Horse chestnut seed extract is most often used for chronic venous insufficiency, where standardized products may help reduce leg swelling, p...
Horse chestnut may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Horse Chestnut + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionHu Zhang Possible
What it is: Hu Zhang (Japanese knotweed root) is a traditional Chinese herb that is one of the richest natural sources of resveratrol and emodin.
Theoretically, hu zhang might increase levels of drugs metabolized by CYP1A2.
Read the full Hu Zhang + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionIndian GooseberryPhyllanthus Emblica, aamalaki, amalaki, +14 more Possible
What it is: Indian gooseberry (amla) is a vitamin C-rich fruit used in Ayurvedic medicine for many purposes, from antioxidant support to cholesterol and...
Theoretically, Indian gooseberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Indian Gooseberry + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionIndian Long PepperPiper Longum, bi Ba, bi Bo, +17 more Possible
What it is: Indian long pepper (pippali) is a spice long used in Ayurvedic medicine and is best known for its piperine content, which may increase how w...
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Indian Long Pepper + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionIndian SnakerootRauvolfia Serpentina, ajmaline, alseroxylon, +16 more Possible
What it is: Indian snakeroot is a traditional Ayurvedic plant that contains reserpine, a compound with real blood-pressure-lowering and sedative effects...
Theoretically, taking Indian snakeroot might cause additive sedative effects.
Read the full Indian Snakeroot + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionIndole-3-carbinol Possible
What it is: Indole-3-carbinol (I3C) is a compound formed when you eat cruciferous vegetables like broccoli and cabbage, and it is sold as a supplement m...
Theoretically, indole-3-carbinol might increase the metabolism of CYP1A2 substrates and lower serum concentrations.
Read the full Indole-3-carbinol + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionInositol NicotinateHexaniacinate D'inositol, hexanicotinoyl Inositol, inositol Hexaniacinate, +5 more Possible
What it is: Inositol nicotinate is a 'no-flush' form of niacin marketed for cholesterol and circulation.
Theoretically, concomitant use of inositol nicotinate with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Inositol Nicotinate + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionIpriflavone7-isopropoxyisoflavone, ipriflavona Possible
What it is: Ipriflavone is a synthetic isoflavone studied mainly for bone health and osteoporosis, but high-quality research has not shown that it relia...
Ipriflavone is thought to competitively inhibit cytochrome P450 1A2 (CYP1A2).
Read the full Ipriflavone + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionIsopropylnorsynephrine Possible
What it is: Isopropylnorsynephrine is a synthetic stimulant chemically related to synephrine, marketed mainly in weight-loss and pre-workout supplements...
Theoretically, taking isopropylnorsynephrine with stimulant drugs might have additive effects and increase the risk of adverse cardiovascular effects.
Read the full Isopropylnorsynephrine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionJackfruitArtocarpus Heterophyllus, arbol Del Pan, baramil, +21 more Possible
What it is: Jackfruit is a large tropical fruit that is nutritious and safe to eat as a food, offering fiber, vitamin C, potassium, and antioxidants.
Theoretically, jackfruit seeds might cause additive sedation when taken with CNS depressants.
Read the full Jackfruit + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionJamaican Dogwood Possible
What it is: Jamaican dogwood is a tree bark traditionally used to promote sleep and ease pain, but high-quality human studies are lacking.
Jamaican dogwood may potentiate sedative effects.
Read the full Jamaican Dogwood + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionJapanese Apricot Possible
What it is: Japanese Apricot (Prunus mume) is a tart fruit used widely in East Asian foods and traditional medicine, often as pickled umeboshi or a conc...
Some constituents of Japanese apricot flower extract might have antiplatelet properties.
Read the full Japanese Apricot + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionJapanese Persimmon Possible
What it is: Japanese persimmon is a nutritious fruit rich in fiber, vitamins, and antioxidant plant compounds, and its leaves and calyx are used in trad...
There is concern that Japanese persimmon leaf constituents might potentiate effects of anticoagulant and antiplatelet drugs.
Read the full Japanese Persimmon + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionJequirityAbrus Precatorius, bead Vine, black-eyed Susan, +19 more Possible
What it is: Jequirity (Abrus precatorius) is a tropical plant whose bright red, black-tipped seeds contain abrin, one of the most toxic plant proteins k...
Evidence from in vitro research suggests that constituents of jequirity beans can inhibit platelet aggregation.
Read the full Jequirity + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionJiaogulanGynostemma Pentaphyllum, adaptogen, adaptogène, +13 more Possible
What it is: Jiaogulan is a climbing vine used in traditional Chinese medicine as an adaptogen and for heart, blood sugar, and cholesterol support.
Theoretically, jiaogulan might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Jiaogulan + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionKhatCatha Edulis, abessinischer Tea, abyssinian Tea, +23 more Possible
What it is: Khat is a plant chewed for its amphetamine-like stimulant effects, but it carries serious risks including high blood pressure, heart problem...
Cathinone, a constituent of khat, appears to have sympathomimetic effects and can increase blood pressure and heart rate.
Read the full Khat + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionKinetin Possible
What it is: Kinetin is a plant growth hormone (a cytokinin) used mainly in topical anti-aging and skincare products, not as an oral dietary supplement.
In vitro research suggests that kinetin inhibits human platelet aggregation and activation.
Read the full Kinetin + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionKiwi Possible
What it is: Kiwi is a nutritious fruit that is rich in vitamin C, fiber, and antioxidants, and it is generally safe to eat as a food.
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Kiwi + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionKratomMitragyna Speciosa, biak-biak, cratom, +16 more Possible
What it is: Kratom is a Southeast Asian plant whose leaves act on the brain's opioid receptors and can produce both stimulant-like and opioid-like effec...
Theoretically, concomitant use might increase the risk for adverse CNS depressant effects.
Read the full Kratom + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionKrill Oil Possible
What it is: Krill oil is a source of omega-3 fatty acids (EPA and DHA) bound to phospholipids, which may help absorption.
Theoretically, krill oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Krill Oil + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionL-arginine2-amino-5-guanidinopentanoic Acid Possible
What it is: L-arginine is an amino acid that the body uses to make nitric oxide, a substance that helps blood vessels relax and widen.
Theoretically, concomitant use of L-arginine with anticoagulant and antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full L-arginine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionLemon BalmMelissa Officinalis, balm, balm Mint, +15 more Possible
What it is: Lemon balm is a gentle, lemon-scented mint-family herb traditionally used to ease stress, support sleep, and calm digestion, and topically f...
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionLemongrassCymbopogon Citratus, abafado, cana Santa, +17 more Possible
What it is: Lemongrass is a fragrant tropical grass widely used as a cooking herb, a tea, and an aromatherapy oil.
Theoretically, lemongrass might decrease the metabolism of CYP3A4 substrates.
Read the full Lemongrass + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionLentinanBeta-glucan Lentinan, lentinane, lentinus Edodes Polysaccharide, +4 more Possible
What it is: Lentinan is a beta-glucan polysaccharide from shiitake mushrooms that is studied mainly as an immune-modulating add-on to cancer chemotherap...
Laboratory research suggests that lentinan might increase the activity of cytochrome P450 2D6 (CYP2D6).
Read the full Lentinan + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionLicoriceGlycyrrhiza Echinate, alcacuz, bois Doux, +17 more Possible
What it is: Licorice root is a traditional remedy used for sore throats, coughs, and digestive complaints, but solid human evidence is limited for most...
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Licorice + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionLimeCitrus Aurantifolia, adam's Apple, bara Nimbu, +11 more Possible
What it is: Lime is a common citrus fruit and a good natural source of vitamin C and plant antioxidants.
Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4.
Read the full Lime + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionLion's Mane MushroomBearded Tooth, crinière De Lion, hedgehog Fungus, +9 more Possible
What it is: Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still li...
Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Lion's Mane Mushroom + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionLotusNelumbo Nucifera, bean Of India, blue Lotus, +20 more Possible
What it is: Lotus is an edible aquatic plant used in food and traditional medicine across Asia, with parts like the seeds, leaves, and flowers taken for...
Theoretically, concurrent use of lotus with other antiplatelet drugs might reduce platelet aggregation and increase the risk of bleeding.
Read the full Lotus + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionLycopene Possible
What it is: Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits.
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionMace Possible
What it is: Mace is the lacy red covering of the nutmeg seed and comes from the same tree as nutmeg.
Several volatile oils in mace, such as methyleugenol, isoeugenol, safrole, myristicin, 1,8-cineole, and geranyl acetate, seem to have sedative effects.
Read the full Mace + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionMagnoliaMagnolia Biondii, beaver Tree, bourgeon Floral De Magnolia, +13 more Possible
What it is: Magnolia bark and flower buds have a long history in traditional Chinese and Japanese medicine, often for stress, sleep, and digestion.
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionMangosteenGarcinia Mangostana, amibiasine, fruit Des Rois, +19 more Possible
What it is: Mangosteen is a tropical fruit whose rind is rich in plant compounds called xanthones that act as antioxidants.
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionMaral Root Possible
What it is: Maral Root (Rhaponticum carthamoides) is a Siberian herb used as an 'adaptogen' and is popular among athletes for stamina and muscle buildin...
In vitro research shows that maral root tincture can reduce platelet aggregation.
Read the full Maral Root + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionMaritime PinePinus Pinaster, condensed Tannins, french Marine Pine Bark Extract, +13 more Possible
What it is: Maritime pine bark extract (often sold as Pycnogenol) is a plant-based antioxidant most studied for circulation, vein, and skin health.
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Maritime Pine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionMarjoramOriganum Majorana, essence De Marjolaine, garden Marjoram, +12 more Possible
What it is: Marjoram is a Mediterranean kitchen herb related to oregano that is widely used in food and traditional medicine for digestive, sleep, and r...
In vitro research suggests that marjoram extract inhibits platelet aggregation and adhesion.
Read the full Marjoram + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionMarsh Labrador TeaRhododendron Tomentosum, james' Tea, lède Des Marais, +13 more Possible
What it is: Marsh Labrador tea is a bog-growing shrub used in folk medicine for coughs, colds, and skin problems, but high-quality human evidence for an...
Marsh Labrador tea can potentiate effects of barbiturates and alcohol.
Read the full Marsh Labrador Tea + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionMeadowsweetFilipendula Ulmaria, barbe De Bouc, barbe De Chèvre, +12 more Possible
What it is: Meadowsweet is a traditional European herb that contains natural salicylates (aspirin-like compounds) and is used mainly for digestive upset...
Theoretically, meadowsweet might have an additive effect with other salicylate-containing drugs, such as aspirin.
Read the full Meadowsweet + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionMesoglycan Possible
What it is: Mesoglycan is a blend of natural sugar-protein compounds (glycosaminoglycans, including heparan sulfate and dermatan sulfate) taken from ani...
Theoretically, combined use might increase bleeding risk.
Read the full Mesoglycan + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionMethoxylated Flavones Possible
What it is: Methoxylated flavones (often called polymethoxyflavones) are a group of plant compounds, found mainly in citrus peel, that include substance...
Some in vitro evidence suggests that methoxylated flavones might induce CYP1A2, possibly by increasing gene transcription.
Read the full Methoxylated Flavones + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionMethylsynephrine Possible
What it is: Methylsynephrine (also called oxilofrine) is a synthetic stimulant sometimes added to weight-loss and pre-workout products, but it is not a...
Methylsynephrine has cardiac stimulant effects.
Read the full Methylsynephrine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionMoringaMoringa Oleifera Possible
What it is: Moringa is a nutrient-rich plant whose leaves are widely used as a food and supplement, especially in parts of the world where malnutrition...
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Moringa + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionMotherwortLeonurus Cardiac, agripalma, agripaume, +16 more Possible
What it is: Motherwort is a traditional herb in the mint family long used for anxiety, heart palpitations, and women's reproductive complaints, but soli...
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionMountain AshSorbus Aucuparia, arbre Aux Grives, corbier D'europe, +12 more Possible
What it is: Mountain ash (rowan) is a northern-hemisphere tree whose bright red berries are traditionally cooked into jams, syrups, and teas.
Taking large amounts of fresh mountain ash berries may cause kidney damage due to its parasorbic acid constituent.
Read the full Mountain Ash + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionN,n-dmpea Possible
What it is: N,N-DMPEA (N,N-dimethylphenethylamine) is a synthetic relative of phenethylamine sometimes marketed in stimulant or pre-workout supplements.
In vitro research shows that N,N-DMPEA strongly inhibits cytochrome P450 2D6 (CYP2D6).
Read the full N,n-dmpea + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionN-acetyl Cysteine (nac)Acetyl Cysteine, mucomyst Possible
What it is: N-acetyl cysteine (NAC) is a supplement form of the amino acid cysteine and a building block for the antioxidant glutathione.
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full N-acetyl Cysteine (nac) + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionNattokinaseBsp, extrait De Natto, fermented Soybeans, +7 more Possible
What it is: Nattokinase is an enzyme from the fermented soybean food natto that may have mild blood-thinning and blood-flow effects.
Nattokinase might increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Nattokinase + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionNeemAzadirachta Indica, arishta, arishtha, +18 more Possible
What it is: Neem is a tree from India used for centuries in traditional medicine, especially for skin, dental, and antimicrobial purposes.
Theoretically, neem leaf extract might increase the levels and clinical effects of CYP1A2 substrates.
Read the full Neem + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionNiacin3-pyridinecarboxylic Acid, vitamin B3 Possible
What it is: Niacin (vitamin B3) is an essential nutrient your body needs for energy and metabolism, and deficiency is uncommon in most developed countri...
Theoretically, niacin may have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Niacin + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionNutmegMyristica Fragrans, buah Pala, jaatipatree, +14 more Possible
What it is: Nutmeg is a popular cooking spice that has long been used in traditional medicine for digestion and other complaints, but there is little so...
Theoretically, nutmeg might increase the risk of additive sedation when taken with CNS depressants.
Read the full Nutmeg + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionOctacosanol Possible
What it is: Octacosanol is a waxy long-chain alcohol from plant sources that is most often promoted for exercise endurance and cholesterol support, but...
Theoretically, octacosanol might inhibit platelet aggregation; however, clinical research suggests that this effect may not be clinically significant.
Read the full Octacosanol + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionOreganoOriganum Vulgare, carvacrol, european Oregano, +13 more Possible
What it is: Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound call...
Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Oregano + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionOregon GrapeMahonia Aquifolium, barberry, berberis, +13 more Possible
What it is: Oregon grape is a shrub whose root contains berberine and related compounds.
Theoretically, Oregon grape might increase the sedative effects of CNS depressants.
Read the full Oregon Grape + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPadang Cassia Possible
What it is: Padang Cassia is a type of cinnamon (Indonesian or Korintje cinnamon) grown mainly in Indonesia and used widely as a kitchen spice.
In vitro research shows that a methanol extract of Padang cassia inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full Padang Cassia + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPagoda Tree Possible
What it is: Pagoda Tree (Styphnolobium japonicum, also called the Japanese pagoda tree) is a traditional Asian medicinal plant best known as a natural s...
Theoretically, pagoda tree might reduce the clearance of caffeine.
Read the full Pagoda Tree + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPalm Oil Possible
What it is: Palm oil is a widely used edible oil pressed from the fruit of the oil palm tree, and red palm oil is a notable source of vitamin A and vita...
Theoretically, palm oil might decrease the effectiveness of antiplatelet or anticoagulant drugs.
Read the full Palm Oil + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPanax NotoginsengPanax Notoginseng, field Seven, noto-gin, +15 more Possible
What it is: Panax notoginseng (sanqi or tienchi ginseng) is a traditional Chinese herb most often used to help with bleeding, bruising, and circulation.
Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Panax Notoginseng + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPantethine Possible
What it is: Pantethine is a derivative of vitamin B5 (pantothenic acid) that some studies suggest may modestly lower cholesterol and triglycerides.
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionParsleyPetroselinum Crispum, common Parsley, garden Parsley, +16 more Possible
What it is: Parsley is a popular culinary herb that is safe to eat in normal food amounts and is a good source of vitamins K and C.
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPassion FlowerPassiflora Incarnata, apricot Vine, burucuya, +18 more Possible
What it is: Passion flower is a traditional calming herb that many people use for anxiety and sleep.
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passion Flower + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPau D'arcoTabebuia Impetiginosa, tabebuia Avellanedae, handroanthus Impetiginosus Possible
What it is: Pau d'arco is a South American tree bark traditionally used for infections and inflammation, and it contains compounds like lapachol that sh...
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPeonyPaeonia Lactiflora, bai Shao, chi Shao, +17 more Possible
What it is: Peony root is a traditional Chinese medicine herb often used for menstrual problems, cramps, and inflammation, frequently as part of combina...
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Peony + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPeppermintMentha X Piperita, black Peppermint, brandy Mint, +12 more Possible
What it is: Peppermint is a popular herb with the best evidence supporting enteric-coated peppermint oil for easing IBS symptoms.
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPhellodendronPhellodendron Amurense, amur Cork Bark, amur Cork Tree, +7 more Possible
What it is: Phellodendron is a traditional Chinese medicine bark (Huang Bai) that contains berberine and other plant compounds with antimicrobial and an...
Theoretically, phellodendron might increase the sedative effects of CNS depressants.
Read the full Phellodendron + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPhenibutBeta-phenyl-gamma-aminobutyric Acid, 4-amino-3-phenylbutyric Acid, b-(aminomethyl)-benzenepropanoic Acid, +7 more Possible
What it is: Phenibut is a synthetic, lab-made central nervous system depressant—not a natural herb—that some people use for anxiety and sleep, but it ca...
Theoretically, phenibut might increase the risk of sedation and respiratory depression when taken with CNS depressants.
Read the full Phenibut + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPhenpromethamine Possible
What it is: Phenpromethamine is a synthetic stimulant drug, not a herb or legitimate dietary supplement.
Theoretically, taking phenpromethamine with stimulant drugs might have additive effects and increase the risk of adverse cardiovascular effects.
Read the full Phenpromethamine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPinellia Ternata Possible
What it is: Pinellia ternata is a tuber used in traditional Chinese medicine, most often for nausea, vomiting, and phlegmy coughs, and almost always as...
Evidence from animal research shows that a Pinellia ternata preparation decreases activity and increases sleeping time.
Read the full Pinellia Ternata + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPlum Possible
What it is: Plums and their dried form (prunes) are common, nutritious foods that are best known for helping relieve constipation thanks to their fiber...
Theoretically, plum juice might have antiplatelet effects.
Read the full Plum + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPolicosanol32c, dotriacontanol, heptacosanol, +8 more Possible
What it is: Policosanol is a mix of waxy alcohols (mostly octacosanol) made from sugar cane or other plant waxes, and it is often marketed as a natural...
Theoretically, taking policosanol with other antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
Read the full Policosanol + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPomegranatePunica Granatum, anardana, dadim, +14 more Possible
What it is: Pomegranate is a nutrient-rich fruit that is high in antioxidants and is widely enjoyed as food and juice.
Theoretically, pomegranate might increase levels of drugs metabolized by CYP2D6.
Read the full Pomegranate + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPoria Mushroom Possible
What it is: Poria mushroom (Fu Ling) is a fungus long used in Traditional Chinese Medicine, mainly as a mild diuretic and digestive and calming aid.
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Mushroom + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPropolisAcide De Cire D'abeille, baume De Propolis, bee Glue, +12 more Possible
What it is: Propolis is a natural, resin-like substance made by bees that has antimicrobial and anti-inflammatory properties in lab studies.
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP2D6.
Read the full Propolis + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPuravive Possible
What it is: Puravive is a branded, multi-ingredient capsule marketed mainly for weight loss by claiming to boost brown fat activity, but there is no pub...
Puravive, a dietary supplement, contains several ingredients that may interact with anticoagulant drugs due to their potential mild anticoagulant effects.
Read the full Puravive + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPurple Nut Sedge Possible
What it is: Purple nut sedge (Cyperus rotundus) is a common weed whose tubers have a long history in Ayurvedic, Chinese, and other traditional medicine...
In vitro, purple nut sedge inhibits platelet aggregation.
Read the full Purple Nut Sedge + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionQuercetin7-pentahydroxyflavone, bioflavonoid, bioflavonoid Complex, +9 more Possible
What it is: Quercetin is a plant flavonoid with antioxidant and anti-inflammatory properties found in many common foods and sold as a supplement.
Theoretically, concomitant use might increase the effects and adverse effects of OAT3 substrates.
Read the full Quercetin + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionRabdosia RubescensRabdosia Rubescens, bing Ling Cao, blushred Rabdosia, +5 more Possible
What it is: Rabdosia rubescens is a Chinese herb traditionally used for sore throats, inflammation, and infections, and its compound oridonin has drawn...
In vitro research shows that oridonin, a constituent of Rabdosia rubescens, induces cytochrome P450 3A4 (CYP3A4) enzyme.
Read the full Rabdosia Rubescens + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionRaspberry Ketone Possible
What it is: Raspberry ketone is a natural aroma compound found in red raspberries that is heavily marketed for weight loss, but there is no good human e...
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketone + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionRauwolscine Possible
What it is: Rauwolscine (alpha-yohimbine) is a stimulant alkaloid closely related to yohimbine that is marketed mainly in fat-burning and pre-workout su...
Theoretically, taking rauwolscine with seizure threshold lowering drugs might increase the risk of adverse convulsant effects.
Read the full Rauwolscine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionRed Raspberry Possible
What it is: Red raspberry leaf is a traditional herbal remedy most often used as a tea in late pregnancy and for menstrual discomfort, but solid scienti...
Theoretically, taking red raspberry leaf with anticoagulant/antiplatelet drugs might increase the risk of bleeding.
Read the full Red Raspberry + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionReishi MushroomGanoderma Lucidum, basidiomycetes Mushroom, champignon Reishi, +15 more Possible
What it is: Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness.
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mushroom + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionResveratrolExtrait De Vin, extrait De Vin Rouge, kojo-kon, +16 more Possible
What it is: Resveratrol is a plant compound found in red grapes, berries, and peanuts that is popular for heart health, anti-aging, and antioxidant supp...
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
Read the full Resveratrol + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionRhubarbRheum Officinale, chinese Rhubarb, da Huang, +13 more Possible
What it is: Rhubarb root has a long history of use as a laxative and in traditional Chinese medicine, and its edible stalks are a common food.
Theoretically, long-term use of anthraquinones from rhubarb might increase the risk of nephrotoxicity when used with nephrotoxic drugs.
Read the full Rhubarb + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionRooibosAspalathus Linearis, green Red Bush, infusion Rooibos, +9 more Possible
What it is: Rooibos is a caffeine-free herbal tea from South Africa that is rich in antioxidants and generally considered safe as a beverage.
Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
Read the full Rooibos + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionRose HipRosa Alba, cynorhodon, cynosbatos, +22 more Possible
What it is: Rose hip is the vitamin C–rich fruit of the wild rose, used traditionally for colds and joint pain.
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rose Hip + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionRosemaryRosmarinus Officinalis, alecrim, compass Plant, +14 more Possible
What it is: Rosemary is a fragrant Mediterranean herb that is safe and flavorful in normal food amounts.
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Rosemary + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSafflowerCarthamus Tinctorius, alazor, american Saffron, +10 more Possible
What it is: Safflower is a thistle-like plant used mainly for its seed oil (a common cooking oil) and its colorful flowers.
High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Safflower + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSaffronCrocus Sativus, autumn Crocus, azafrán, +16 more Possible
What it is: Saffron is a costly spice that has shown promise in early studies for mild-to-moderate depression and some mood and PMS symptoms, but most r...
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSageSalvia Officinalis, broadleaf Sage, common Sage, +14 more Possible
What it is: Sage is a common kitchen herb that is generally safe in food amounts and is traditionally used for sore throats, digestion, sweating, and me...
Theoretically, taking sage might increase the sedative and adverse effects of CNS depressants.
Read the full Sage + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSassafrasSassafras Albidum, ague Tree, bois De Cannelle, +7 more Possible
What it is: Sassafras is an aromatic North American tree whose root bark and oil were once popular in teas and as a flavoring, but it contains safrole,...
Theoretically, concomitant use of sassafras with drugs with sedative properties may cause additive sedative effects.
Read the full Sassafras + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSaw PalmettoSerenoa Repens, american Dwarf Palm Tree, baies Du Palmier Scie, +8 more Possible
What it is: Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH).
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSceletium Possible
What it is: Sceletium (often sold as 'kanna') is a South African plant traditionally used to ease stress and lift mood.
Theoretically, concomitant use of sceletium and CNS depressants might result in additive sedative effects.
Read the full Sceletium + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSchizonepeta Possible
What it is: Schizonepeta is a mint-family herb long used in traditional Chinese medicine, usually as part of combination formulas for colds, fevers, and...
Animal research suggests that schizonepetin, a monoterpene constituent of schizonepeta, inhibits cytochrome P450 (CYP) 2D6.
Read the full Schizonepeta + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSea BuckthornAnanas De Sibérie, argasse, argousier, +17 more Possible
What it is: Sea buckthorn is a berry-bearing shrub rich in vitamins, carotenoids, and fatty acids that people use for skin, eye, digestive, and heart he...
Theoretically, sea buckthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Sea Buckthorn + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSecurinega Suffruticosa Possible
What it is: Securinega suffruticosa is a shrub used in traditional East Asian medicine, best known for an alkaloid called securinine that strongly stimu...
Theoretically, taking Securinega suffruticosa with stimulant drugs might increase the risk of serious adverse effects.
Read the full Securinega Suffruticosa + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSelenium Possible
What it is: Selenium is an essential trace mineral your body needs in small amounts for thyroid function, antioxidant defense, and immune health.
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSerrapeptase Possible
What it is: Serrapeptase is an enzyme marketed to reduce inflammation, swelling, pain, and mucus, but the human evidence is limited and mostly low quali...
Theoretically, taking serrapeptase with drugs that have antiplatelet or anticoagulant effects might increase the risk of bruising and bleeding.
Read the full Serrapeptase + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionShepherd's PurseCapsella Bursa-pastoris, blind Weed, bolsa Del Pastor, +14 more Possible
What it is: Shepherd's purse is a traditional herb most often used to help slow heavy menstrual bleeding and other minor bleeding, but solid human resea...
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionShiitake Mushroom Possible
What it is: Shiitake is a popular edible mushroom that is nutritious and safe to eat as food for most people.
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Shiitake Mushroom + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSkullcapScutellaria Lateriflora, american Skullcap, blue Pimpernel, +15 more Possible
What it is: American skullcap is an herb traditionally used to calm anxiety and promote relaxation, but solid human evidence is very limited.
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Skullcap + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSlippery ElmIndian Elm, moose Elm, olmo Americano, +7 more Possible
What it is: Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and ir...
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSorrelRumex Acetosa, acedera, azeda-brava, +13 more Possible
What it is: Sorrel is a tangy, leafy herb used in cooking and traditional medicine, often for congestion, digestion, and inflammation.
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sorrel + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSoy Possible
What it is: Soy is a nutritious bean that is a staple food and a popular source of plant protein and isoflavones.
Theoretically, soy might reduce the clearance of caffeine.
Read the full Soy + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSpearmintMentha Spicata, curled Mint, fish Mint, +16 more Possible
What it is: Spearmint is a common culinary mint that is generally safe in food and tea amounts.
Theoretically, spearmint might alter the sedative effects of CNS depressants.
Read the full Spearmint + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionStrawberry Possible
What it is: Strawberry is a popular, nutrient-rich fruit that supplies vitamin C, fiber, and antioxidant plant compounds.
In vitro and animal research suggests that strawberry extract can inhibit platelet aggregation due to its phenolic content.
Read the full Strawberry + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSulforaphane Possible
What it is: Sulforaphane is a natural compound found in broccoli and other cruciferous vegetables that has shown promising antioxidant and anti-inflamma...
Theoretically, sulforaphane might alter the levels and clinical effects of CYP1A2 substrates.
Read the full Sulforaphane + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSummer Savory Possible
What it is: Summer savory is a common kitchen herb that has long been used as a tea or remedy for digestive complaints and minor infections.
In vitro research suggests that summer savory extract inhibits platelet aggregation and adhesion.
Read the full Summer Savory + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSwallowroot Possible
What it is: Swallowroot (Decalepis hamiltonii) is a root used in South Indian folk medicine and as a food flavoring, often pickled or made into a coolin...
Theoretically, swallowroot might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Swallowroot + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSweet AnnieArtemisia Annua, absinthe Sauvage, ajenjo Silvestre, +11 more Possible
What it is: Sweet Annie (Artemisia annua) is the source of artemisinin, a compound used in prescription antimalarial drugs.
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Sweet Annie + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSweet CloverMelilotus Officinalis, angipars, casse Lunettes, +14 more Possible
What it is: Sweet clover is a traditional European herb most often promoted for vein problems and leg swelling, but high-quality human evidence is limit...
Theoretically, fresh sweet clover might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Sweet Clover + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSweet Vernal Grass Possible
What it is: Sweet Vernal Grass is a fragrant European meadow grass best known for the sweet, hay-like smell it gets from coumarin.
Hay prepared from dried sweet vernal grass contains an anticoagulant, dicoumarol, which has been associated with fatal hemorrhages in animals.
Read the full Sweet Vernal Grass + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionTamarind Possible
What it is: Tamarind is a tangy tropical fruit widely used in cooking and traditional medicine, mainly for digestion and as a mild laxative.
Theoretically, tamarind fruit extract might increase the effects and side effects of aspirin.
Read the full Tamarind + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionTarragonArtemisia Dracunculus, armoise Âcre, dragonne, +8 more Possible
What it is: Tarragon is a flavorful culinary herb that has been used in traditional medicine for digestion, sleep, and other complaints, but solid human...
Evidence from animal research suggests that tarragon essential oil can cause sedation and motor impairment when administered intraperitoneally at a dose of 1 mL/kg.
Read the full Tarragon + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionTerminaliaTerminalia Arjuna, abhaya, amandier Indien, +19 more Possible
What it is: Terminalia is a group of traditional Ayurvedic tree species (most notably Terminalia arjuna) used for heart, digestive, and general wellness...
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Terminalia + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionTheacrine Possible
What it is: Theacrine is a caffeine-like compound found naturally in certain tea plants and is sold in supplements for energy, focus, and mood.
Theoretically, theacrine might alter the effects of CNS depressants.
Read the full Theacrine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionThuja Possible
What it is: Thuja, also called northern white cedar or arborvitae, is a tree whose leaf and oil have a long history in folk and homeopathic medicine, es...
Thuja products can contains significant amounts of thujone, a neurotoxin.
Read the full Thuja + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionThunder God VineTripterygium Wilfordii, huang-t'eng Ken, lei Gong Teng, +8 more Possible
What it is: Thunder God Vine is a Chinese herb studied mainly for rheumatoid arthritis and other autoimmune conditions, with some promising but limited...
Theoretically, thunder god vine might increase the levels and clinical effects of CYP1A2 substrates.
Read the full Thunder God Vine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionThymeThymus Vulgaris, farigoule, farigoulette, +14 more Possible
What it is: Thyme is a common kitchen herb that has long been used for coughs, sore throats, and digestive complaints.
Theoretically, thyme leaf extract might have additive effects with anticoagulant or antiplatelet drugs.
Read the full Thyme + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionTianeptine Possible
What it is: Tianeptine is a prescription antidepressant in some countries, but it is NOT approved by the FDA in the United States and is illegally sold...
Tianeptine has sedative effects; high doses may have additive effects with other CNS depressants.
Read the full Tianeptine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionTinospora Cordifolia Possible
What it is: Tinospora cordifolia, known as Guduchi or Giloy in Ayurvedic medicine, is a climbing plant traditionally used to support immunity and treat...
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
Read the full Tinospora Cordifolia + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionTiratricol Possible
What it is: Tiratricol (also called TRIAC) is a powerful synthetic thyroid hormone metabolite, not a natural herb, and it has been illegally added to so...
Theoretically, tiratricol might increase the hypoprothrombinemic effects of oral anticoagulants.
Read the full Tiratricol + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionTragacanthAdragante, astragale Adragant, astragale De Marseille, +14 more Possible
What it is: Tragacanth is a plant gum used mainly as a thickener and emulsifier in foods, cosmetics, and medicines, and traditionally to soothe the thro...
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Tragacanth + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionTree Of Heaven Possible
What it is: Tree of Heaven (Ailanthus altissima) is a fast-growing, invasive tree whose bark has been used in traditional medicine, mostly for digestive...
Theoretically, tree of heaven extract might reduce platelet aggregation and increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Read the full Tree Of Heaven + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionTurmericCurcuma Longa, curcuma, curcumae Longa, +17 more Possible
What it is: Turmeric is a popular spice whose main active compounds, curcuminoids, are studied mostly for inflammation and joint pain.
Turmeric might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Turmeric + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionUva UrsiArctostaphylos Uva-ursi, arberry, arbousier, +16 more Possible
What it is: Uva ursi is a traditional herb used mainly for urinary tract infections, and its leaves contain a compound called arbutin that may have anti...
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionValerianValeriana Officinalis, all-heal, amantilla, +10 more Possible
What it is: Valerian is an herb whose root is widely used as a natural sleep aid and for calming nerves.
Valerian can have additive sedative effects when used concomitantly with CNS depressant drugs.
Read the full Valerian + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionVanadium Possible
What it is: Vanadium is a trace mineral found in tiny amounts in food, and people get plenty from a normal diet.
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionVinpocetineEburnamenine-14-carboxylic Acid, ay-27255, cavinton, +11 more Possible
What it is: Vinpocetine is a lab-made compound based on a chemical from the periwinkle plant, and it is marketed mainly for memory and brain health.
Vinpocetine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Vinpocetine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionVitamin EAlpha-tocopherol, beta-tocopherol, delta-tocopherol, +1 more Possible
What it is: Vitamin E is an essential fat-soluble vitamin and antioxidant that most people get in adequate amounts from a normal diet.
Theoretically, vitamin E might induce metabolism of CYP3A4, possibly reducing the levels CYP3A4 substrates.
Read the full Vitamin E + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionWasabiEutrema Japonicum, cochlearia Wasabi, eutrema Wasabi. Cardamine Pseudowasabi, +1 more Possible
What it is: Wasabi is best known as the pungent green condiment served with sushi, made from a Japanese plant in the cabbage family.
Theoretically, wasabi might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Wasabi + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionWheatgrassTriticum Aestivum, agropyre, blé En Herbe, +7 more Possible
What it is: Wheatgrass is the young grass of the wheat plant, taken as a juice or powder, and is mainly used as a concentrated source of vitamins and pl...
Theoretically, wheatgrass might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Wheatgrass + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionWhite Pepper Possible
What it is: White pepper comes from the same plant as black pepper and is mostly used as a kitchen spice.
In vitro evidence suggests that some constituents of white pepper inhibit cytochrome P450 2D6 (CYP2D6).
Read the full White Pepper + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionWild CherryPrunus Serotine, american Black Cherry, bird Cherry, +12 more Possible
What it is: Wild cherry bark is a traditional cough remedy found in many old-fashioned cough syrups and lozenges, but there is little modern scientific...
In vitro research suggests that wild cherry can inhibit cytochrome P450 3A4 (CYP3A4) enzymes.
Read the full Wild Cherry + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionWild LettuceLactuca Virosa, acrid Lettuce, allubbyne, +13 more Possible
What it is: Wild lettuce is a traditional herb used mainly for sleep, anxiety, and pain, but solid human research supporting these uses is very limited.
Theoretically, concomitant use with drugs with sedative effects might cause additive therapeutic effects and adverse effects.
Read the full Wild Lettuce + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionYin ChenArmoise à Balais, armoise Capillaire, artemisia Officinalis, +11 more Possible
What it is: Yin Chen is a traditional Chinese medicine herb used mainly for liver and gallbladder complaints and jaundice.
Theoretically, yin chen might enhance the therapeutic and adverse effects of other CNS depressants.
Read the full Yin Chen + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionYohimbePausinystalia Yohimbe, 11-hydroxy Yohimbine, coryanthe Yohimbe, +7 more Possible
What it is: Yohimbe is a West African tree bark that contains yohimbine, a compound mainly promoted for erectile dysfunction and as an aphrodisiac.
Theoretically, yohimbe might increase the levels and adverse effects of CYP2D6 substrates.
Read the full Yohimbe + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionZedoary Possible
What it is: Zedoary is a ginger-family root used in traditional Asian and Indian medicine, mostly for digestion and as a spice.
Theoretically, zedoary might increase levels of drugs metabolized by CYP3A4.
Read the full Zedoary + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionZizyphusZiziphus Jujuba, anèbe, annab, +20 more Possible
What it is: Zizyphus (jujube) is an edible fruit and traditional remedy used mainly for sleep, anxiety, and digestion.
Theoretically, zizyphus might cause additive sedative effects when taken with CNS depressants.
Read the full Zizyphus + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionArnicaAmerican Arnica, arctic Arnica, arnica Flos, +14 more Unlikely
What it is: Arnica is a daisy-family plant used mainly in topical and homeopathic products for bruising, muscle soreness, and pain.
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBlue-green AlgaeAfa, algae, algues Bleu-vert Du Lac Klamath, +16 more Unlikely
What it is: Blue-green algae are nutrient-rich aquatic microorganisms (such as spirulina and Klamath Lake algae) taken as a supplement for energy, nutri...
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Blue-green Algae + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionChinese Prickly Ash Unlikely
What it is: Chinese Prickly Ash is the fruit husk of Zanthoxylum bungeanum, best known as the Sichuan pepper that creates a tingling, numbing sensation...
Chinese prickly ash might inhibit platelet aggregation.
Read the full Chinese Prickly Ash + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionDocosahexaenoic Acid (dha)Adh, dha, fish Oil Fatty Acid, +7 more Unlikely
What it is: DHA is an omega-3 fatty acid found in fatty fish and algae that is a building block for the brain, nervous system, and eyes.
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Docosahexaenoic Acid (dha) + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionFenugreekTrigonella Foenum-graecum, alholva, bird's Foot, +14 more Unlikely
What it is: Fenugreek is a common kitchen spice that is also taken as a supplement, mainly for blood sugar, cholesterol, and to support breast milk prod...
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionForsythia Unlikely
What it is: Forsythia is a traditional Chinese herb, used mainly for cold and flu symptoms and as part of multi-herb formulas.
Theoretically, taking forsythia with anticoagulant or antiplatelet drugs might increase the risk of bleeding due to decreased platelet aggregation.
Read the full Forsythia + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionIp-6 Unlikely
What it is: IP-6 (inositol hexaphosphate, also called phytic acid or phytate) is a natural compound found in high-fiber plant foods and sold as a supple...
Theoretically, concomitant use of IP-6 with drugs that affect platelet aggregation may increase the risk of bleeding.
Read the full Ip-6 + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionLavenderLavandula Angustifolia, alhucema, common Lavender, +14 more Unlikely
What it is: Lavender is a fragrant herb most popular for promoting relaxation, easing anxiety, and supporting sleep, with some encouraging evidence for...
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionNiacinamide Unlikely
What it is: Niacinamide (also called nicotinamide) is a form of vitamin B3 used in supplements and skin-care products.
Theoretically, niacinamide may have additive effects when used with anticoagulant or antiplatelet drugs, especially in patients on hemodialysis.
Read the full Niacinamide + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSweet WoodruffGalium Odoratum, aspérula, aspérule, +9 more Unlikely
What it is: Sweet woodruff is a fragrant European herb traditionally used for digestion, calming, and various other complaints, but solid human evidence...
Theoretically, concomitant use might increase the effects of some anticoagulant and antiplatelet drugs and increase the risk of bleeding.
Read the full Sweet Woodruff + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionThyroid Extract Likely
What it is: Thyroid extract supplements are made from dried animal thyroid gland and may contain real thyroid hormones (T3 and T4), but the amounts in o...
Food and medications can interfere with thyroid hormone absorption.
Read the full Thyroid Extract + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAdenosineAdenosine, adenosine Monophosphate (amp), adenosine-5-monophosphate (a5mp), +2 more Possible
What it is: Adenosine is a natural building block your body uses for energy and cell signaling, and a prescription injectable version is used by doctors...
Methylxanthines are competitive antagonists of adenosine and can block its pharmacologic effects.
Read the full Adenosine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAegeline Possible
What it is: Aegeline is a compound originally identified in the bael tree (Aegle marmelos) that gained attention because it was added to some weight-los...
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full Aegeline + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAgarAgar-agar, agarose, agarose Gel, +17 more Possible
What it is: Agar is a plant-based gel made from red seaweed that is widely used as a vegetarian alternative to gelatin and as a source of dietary fiber.
Agar forms a thick gel, which may disrupt the absorption of nutrients and medications.
Read the full Agar + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAlginAlginate, alginate De Calcium, alginate De Magnésium, +12 more Possible
What it is: Algin (alginate) is a fiber-like substance from brown seaweed that is widely used as a thickener, gel, and binder in foods and medicines.
Theoretically, algin can alter the absorption of oral drugs.
Read the full Algin + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBaelAegle Marmelos, arbre De Bael, bael Tree, +16 more Possible
What it is: Bael is a fruit-bearing tree long used in traditional Indian (Ayurvedic) medicine, mostly for digestive problems like diarrhea and indigesti...
Bael extract and its constituent marmesinin inhibited cytochrome P450 1A2 (CYP1A2) activity in vitro.
Read the full Bael + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBlack PsylliumAfrican Plantain, brown Psyllium, dietary Fiber, +16 more Possible
What it is: Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive...
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Black Psyllium + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBlond PsylliumPlantago Ovata, balle De Psyllium, blond Plantago, +14 more Possible
What it is: Blond psyllium is a soluble fiber from the seed husks of Plantago ovata, and it is one of the better-studied fiber supplements.
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Blond Psyllium + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionBroccoli Sprout Possible
What it is: Broccoli sprouts are young broccoli seedlings rich in a compound called sulforaphane, which is being studied for antioxidant, anti-inflammat...
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Sprout + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCalea Zacatechichi Possible
What it is: Calea zacatechichi, often called 'dream herb,' is a Mexican plant traditionally used to encourage vivid dreams and to treat digestive compla...
Theoretically, Calea zacatechichi might increase the sedative effects of CNS depressants.
Read the full Calea Zacatechichi + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCarobCeratonia Siliqua, algarrobo, carob Flour, +16 more Possible
What it is: Carob is a Mediterranean tree whose pods are widely used as a caffeine-free, naturally sweet cocoa alternative and as a thickener (carob gum...
Theoretically, carob might also impair the absorption of oral drugs.
Read the full Carob + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCascara SagradaFrangula Purshiana, rhamnus Purshiana, bitter Bark, +13 more Possible
What it is: Cascara sagrada is a stimulant laxative made from the aged bark of a Pacific Northwest tree, used mainly for short-term relief of constipati...
Theoretically, cascara sagrada might decrease the effects of CYP3A4 substrates.
Read the full Cascara Sagrada + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionChromium Possible
What it is: Chromium is an essential trace mineral involved in how the body handles sugar and fat.
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionEurycoma LongifoliaAkar Pasak Bumi, ali's Umbrella, ali's Walking Stick, +17 more Possible
What it is: Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some...
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionFucus VesiculosusBlack Tang, bladder Fucus, bladder Wrack, +14 more Possible
What it is: Fucus vesiculosus (bladderwrack) is a brown seaweed rich in iodine that has been used traditionally for thyroid concerns, weight, and skin.
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Fucus Vesiculosus + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionHempCannabis Sativa, cheungsam, fiber Hemp, +14 more Possible
What it is: Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generall...
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionHibiscus SabdariffaHibiscus Sabdariffa, agua De Jamaica, ambashthaki, +16 more Possible
What it is: Hibiscus sabdariffa is a tart, cranberry-flavored plant most often consumed as a tea, and its best-studied use is for mildly lowering blood...
Theoretically, Hibiscus sabdariffa extract might reduce the metabolism of CYP2D6 substrates.
Read the full Hibiscus Sabdariffa + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionHoneyBeri Honey, blossom Honey, buckwheat Honey, +13 more Possible
What it is: Honey is a natural food with some real, modest evidence for easing coughs and helping certain wounds, especially when special medical-grade...
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Honey + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionKaraya GumBassora Tragacanth, goma Karaya, gomme Karaya, +14 more Possible
What it is: Karaya gum is a natural plant gum from the Sterculia tree that is mostly used as a bulk-forming laxative and as a thickener or adhesive in f...
Co-administration of oral drugs with bulk forming laxatives such as karaya gum may decrease, increase, or have no effect on the absorption of drugs.
Read the full Karaya Gum + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionMarshmallowAlthaea Officinalis, altea, alteia, +16 more Possible
What it is: Marshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sor...
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionN-methyltyramine Possible
What it is: N-methyltyramine is a natural compound related to tyramine that is found in bitter orange, barley, and other plants, and it is often added t...
N-methyltyramine is thought to have stimulant effects.
Read the full N-methyltyramine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionOctopamine Possible
What it is: Octopamine is a stimulant-like compound found in small amounts in some plants (such as bitter orange) and made naturally in the body.
Octopamine is thought to have stimulant effects.
Read the full Octopamine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionRhodiolaRhodiola Rosea, arctic Root, golden Root, +12 more Possible
What it is: Rhodiola is an herb traditionally used to fight fatigue and help the body cope with stress.
Theoretically, rhodiola might increase the risk of adverse effects when taken with CNS depressants.
Read the full Rhodiola + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionTyramine Possible
What it is: Tyramine is a natural compound formed when certain proteins break down, and it is found in aged cheeses, cured meats, fermented foods, and s...
Theoretically, taking tyramine with stimulant drugs might increase the risk of adverse cardiovascular effects.
Read the full Tyramine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionVitamin C Possible
What it is: Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements.
Acidification of the urine by vitamin C might increase aspirin levels.
Read the full Vitamin C + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionVitamin DErgocalciferol, cholecalciferol Possible
What it is: Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function.
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionXanthan GumBacterial Polysaccharide, corn Sugar Gum, goma Xantana, +7 more Possible
What it is: Xanthan gum is a fermentation-made fiber widely used to thicken and stabilize foods and to thicken liquids for people with swallowing diffic...
Theoretically, xanthan gum can alter the absorption of oral drugs due to its fiber qualities.
Read the full Xanthan Gum + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAcerolaMalpighia Emarginata, acerola Cherry, barbados Cherry, +9 more Unlikely
What it is: Acerola is a small tropical fruit prized for its very high natural vitamin C content, and it is mostly used as a food-based source of vitami...
Theoretically, acerola might reduce the clearance of aspirin; however, its vitamin C content is likely too low to produce clinically significant effects.
Read the full Acerola + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAlgal OilDha-s Oil, dha-t Oil, dhasco Oil, +7 more Unlikely
What it is: Algal oil is a plant-based source of the omega-3 fats DHA and (in some products) EPA, making it a popular alternative to fish oil for vegeta...
Theoretically, algal oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Algal Oil + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAsian Water PlantainAlisma Plantago-aquatica, dong Fang Ze Xie, jilgyeongitaegsa, +6 more Unlikely
What it is: Asian water plantain (Ze Xie) is a rhizome long used in traditional Chinese medicine, mainly as a diuretic and for fluid retention.
Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg orally daily and does not cause harm to the body.
Read the full Asian Water Plantain + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCalendulaCalendula Officinalis, caléndula, calendule, +13 more Unlikely
What it is: Calendula is a flowering plant whose petals are used mainly in skin creams, oils, and ointments to soothe minor irritation and support wound...
Theoretically, calendula might have additive effects when used with CNS depressants, although this appears to be unlikely.
Read the full Calendula + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionDiindolylmethaneDim Unlikely
What it is: Diindolylmethane (DIM) is a compound made when your body digests cruciferous vegetables, and it is sold as a supplement mainly for hormone b...
Theoretically, diindolylmethane might lower serum levels of CYP1A2 substrates.
Read the full Diindolylmethane + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionFish Oil Unlikely
What it is: Fish oil provides omega-3 fatty acids (EPA and DHA) that are best known for lowering high triglyceride levels.
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fish Oil + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionGamma-aminobutyric Acid (gaba)Acide Bêta-phényl-gamma-amino-butyrique, acide Gamma-aminobutyrique, Ácido Gama-aminobutríco, +3 more Unlikely
What it is: GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety,...
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gamma-aminobutyric Acid (gaba) + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionHumann Superbeets Heart Chews Unlikely
What it is: SuperBeets Heart Chews are a beetroot- and grape-seed-based supplement marketed to support healthy blood flow, blood pressure, and nitric ox...
Each serving of HumanN SuperBeets includes 150mg of grape seed extract (2 chews).
Read the full Humann Superbeets Heart Chews + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionKetogenic Diet Unlikely
What it is: The ketogenic diet is a very low-carbohydrate, high-fat eating plan that shifts the body to burn fat for fuel.
Although there is some concern that the ketogenic diet might have additive effects when used with anticoagulant and antiplatelet drugs, most clinical research does not show this effect.
Read the full Ketogenic Diet + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionMagnesiumChelated Magnesium, dimagnesium Malate, epsom Salts, +10 more Unlikely
What it is: Magnesium is an essential mineral your body needs for muscles, nerves, blood pressure, and many other functions, and supplements are useful...
Theoretically, magnesium may have antiplatelet effects, but the evidence is conflicting.
Read the full Magnesium + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionMilk ThistleSilybum Marianum, artichaut Sauvage, blessed Milk Thistle, +12 more Unlikely
What it is: Milk thistle is a popular herbal supplement most often used for liver health, and its main active component is a group of compounds called s...
It is unclear if milk thistle inhibits CYP3A4; research is conflicting.
Read the full Milk Thistle + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionMommy's Bliss Gripe Water Unlikely
What it is: Mommy's Bliss Gripe Water is a sugar-free, alcohol-free liquid made with fennel and ginger that parents use to soothe gassy, colicky, or fus...
Mommy's Bliss Gripe Water contains fennel seed.
Read the full Mommy's Bliss Gripe Water + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionMulleinVerbascum Densiflorum Unlikely
What it is: Mullein is a traditional herbal remedy most often used as a tea or syrup to soothe coughs, sore throats, and respiratory irritation.
Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot.
Read the full Mullein + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionPolypodium Leucotomos Unlikely
What it is: Polypodium leucotomos is a fern extract taken by mouth, mostly studied as an add-on to (not a replacement for) sunscreen and for certain lig...
Theoretically, Polypodium leucotomos might increase levels of drugs metabolized by CYP3A4.
Read the full Polypodium Leucotomos + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionRed CloverTrifolium Pratense, beebread, clovone, +17 more Unlikely
What it is: Red clover is a plant rich in isoflavones (plant compounds with weak estrogen-like activity) that is most often used for menopause symptoms...
Theoretically, red clover might increase levels of drugs metabolized by CYP1A2; however, a small clinical study found no effect.
Read the full Red Clover + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionTangerine Unlikely
What it is: Tangerine is a sweet citrus fruit that is a good source of vitamin C and other nutrients, and is widely enjoyed as food.
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Tangerine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionTheanine Unlikely
What it is: Theanine (usually L-theanine) is an amino acid found naturally in tea leaves that many people take to feel calmer and less stressed without...
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Theanine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionTocotrienolsAlpha-tocotrienol, beta-tocotrienol, delta-tocotrienol, +1 more Unlikely
What it is: Tocotrienols are a less common form of vitamin E with strong antioxidant activity studied mostly for cholesterol, liver, and heart health.
Concomitant use of tocotrienols with anticoagulant or antiplatelet agents might increase the risk of bleeding.
Read the full Tocotrienols + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionTurpentine OilPinus Palustris, aceite De Trementina, essence De Térébenthine, +9 more Unlikely
What it is: Turpentine oil is a strong-smelling pine resin product used mostly in tiny amounts in topical rubs for muscle aches and congestion.
There is some concern that turpentine oil can inhibit CYP1A2 enzyme activity by up to 90% via induction of inflammation and subsequent downregulation of CYP activity.
Read the full Turpentine Oil + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionUmckaloaboAfrican Geranium Unlikely
What it is: Umckaloabo is a root extract from a South African geranium that is most studied for short-term relief of acute bronchitis and other respirat...
Theoretically, Pelargonium sidoides might increase the risk of bleeding when taken with anticoagulant and antiplatelet drugs.
Read the full Umckaloabo + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionCan You Take It With Aspirin, Caffeine, Dihydrocodeine Bitartrate?
One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.
Can you take Niacin with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, niacin may have additive effects when used with anticoagulant or antiplatelet drugs.
Full Niacin + Aspirin, Caffeine, Dihydrocodeine Bitartrate answerCan you take Adenosine with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Methylxanthines are competitive antagonists of adenosine and can block its pharmacologic effects.
Full Adenosine + Aspirin, Caffeine, Dihydrocodeine Bitartrate answerCan you take Flaxseed Oil with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk...
Full Flaxseed Oil + Aspirin, Caffeine, Dihydrocodeine Bitartrate answerCan you take Niacinamide with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, niacinamide may have additive effects when used with anticoagulant or antiplatelet drugs, especially in patients on hemodialy...
Full Niacinamide + Aspirin, Caffeine, Dihydrocodeine Bitartrate answerCan you take Black Currant with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, black currant seed oil might increase the risk of bleeding if used in combination with anticoagulant or antiplatelet drugs.
Full Black Currant + Aspirin, Caffeine, Dihydrocodeine Bitartrate answerCan you take Atractylodes with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Full Atractylodes + Aspirin, Caffeine, Dihydrocodeine Bitartrate answerCan you take Babassu with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Evidence from animal research suggests that babassu has antithrombotic effects.
Full Babassu + Aspirin, Caffeine, Dihydrocodeine Bitartrate answerCan you take Bacopa with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Full Bacopa + Aspirin, Caffeine, Dihydrocodeine Bitartrate answerCan you take Baikal Skullcap with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Full Baikal Skullcap + Aspirin, Caffeine, Dihydrocodeine Bitartrate answerCan you take Banderol with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Small lab studies have found that Banderol may also inhibit OATP1B3 (Organic Anion Transporting Polypeptide 1B3), in addition to OATP1B1.
Full Banderol + Aspirin, Caffeine, Dihydrocodeine Bitartrate answerCan you take Basil with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, basil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Full Basil + Aspirin, Caffeine, Dihydrocodeine Bitartrate answerCan you take Bay Leaf with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking bay leaf in large amounts may enhance the therapeutic and adverse effects of sedatives.
Full Bay Leaf + Aspirin, Caffeine, Dihydrocodeine Bitartrate answerCan you take Bear's Garlic with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro research shows that bear's garlic and some of its constituents can inhibit platelet aggregation.
Full Bear's Garlic + Aspirin, Caffeine, Dihydrocodeine Bitartrate answerCan you take Beet with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, beet might increase the levels of CYP3A4 substrates.
Full Beet + Aspirin, Caffeine, Dihydrocodeine Bitartrate answerCan you take Berberine with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, berberine might increase the sedative effects of CNS depressants.
Full Berberine + Aspirin, Caffeine, Dihydrocodeine Bitartrate answerCan you take Beta-methylphenethylamine (bmpea) with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, BMPEA might increase the levels and clinical effects of CYP2D6 substrates.
Full Beta-methylphenethylamine (bmpea) + Aspirin, Caffeine, Dihydrocodeine Bitartrate answerCan you take Bilberry with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Full Bilberry + Aspirin, Caffeine, Dihydrocodeine Bitartrate answerCan you take Biofeedback with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. There is some concern that electroencephalogram (EEG) biofeedback might lower the seizure threshold in some patients.
Full Biofeedback + Aspirin, Caffeine, Dihydrocodeine Bitartrate answerCan you take Bishop's Weed with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Full Bishop's Weed + Aspirin, Caffeine, Dihydrocodeine Bitartrate answerCan you take Bismuth with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, use of bismuth subgallate or other bismuth salts might reduce the effects of anticoagulant/antiplatelet drugs.
Full Bismuth + Aspirin, Caffeine, Dihydrocodeine Bitartrate answerWhat Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
How Does Our Interaction Checker Work?
Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).
So the check works in three steps: (1) Aspirin, Caffeine, Dihydrocodeine Bitartrate is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Aspirin, Caffeine, Dihydrocodeine Bitartrate, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.
Aspirin, Caffeine, Dihydrocodeine Bitartrate sits in 18 interaction categories. Open any one to see what the group means:
Anticoagulant/Antiplatelet Drugs 202 ingredients
Blood-thinning medications. Supplements with their own effects on clotting or platelets can add up with these drugs and raise bleeding risk.
202 of the supplement ingredients on this page reach Aspirin, Caffeine, Dihydrocodeine Bitartrate through this category.
Cytochrome P450 3A4 (Cyp3A4) Substrates 121 ingredients
A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.
121 of the supplement ingredients on this page reach Aspirin, Caffeine, Dihydrocodeine Bitartrate through this category.
Cytochrome P450 1A2 (Cyp1A2) Substrates 79 ingredients
A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.
79 of the supplement ingredients on this page reach Aspirin, Caffeine, Dihydrocodeine Bitartrate through this category.
Cns Depressants 78 ingredients
Central-nervous-system depressants. Sedating supplements can intensify drowsiness and slowed reactions when combined.
78 of the supplement ingredients on this page reach Aspirin, Caffeine, Dihydrocodeine Bitartrate through this category.
Cytochrome P450 2D6 (Cyp2D6) Substrates 60 ingredients
A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.
60 of the supplement ingredients on this page reach Aspirin, Caffeine, Dihydrocodeine Bitartrate through this category.
Stimulant Drugs 44 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
44 of the supplement ingredients on this page reach Aspirin, Caffeine, Dihydrocodeine Bitartrate through this category.
Aspirin 22 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
22 of the supplement ingredients on this page reach Aspirin, Caffeine, Dihydrocodeine Bitartrate through this category.
Caffeine 17 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
17 of the supplement ingredients on this page reach Aspirin, Caffeine, Dihydrocodeine Bitartrate through this category.
Oral Drugs 17 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
17 of the supplement ingredients on this page reach Aspirin, Caffeine, Dihydrocodeine Bitartrate through this category.
Nephrotoxic Drugs 6 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
6 of the supplement ingredients on this page reach Aspirin, Caffeine, Dihydrocodeine Bitartrate through this category.
Seizure Threshold Lowering Drugs 6 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
6 of the supplement ingredients on this page reach Aspirin, Caffeine, Dihydrocodeine Bitartrate through this category.
Methylxanthines 5 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
5 of the supplement ingredients on this page reach Aspirin, Caffeine, Dihydrocodeine Bitartrate through this category.
Narcotic Drugs 5 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
5 of the supplement ingredients on this page reach Aspirin, Caffeine, Dihydrocodeine Bitartrate through this category.
Nonsteroidal Anti-Inflammatory Drugs (Nsaids) 5 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
5 of the supplement ingredients on this page reach Aspirin, Caffeine, Dihydrocodeine Bitartrate through this category.
Organic Anion Transporter 1 (Oat1) Substrates 4 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
4 of the supplement ingredients on this page reach Aspirin, Caffeine, Dihydrocodeine Bitartrate through this category.
Organic Anion Transporter 3 (Oat3) Substrates 4 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
4 of the supplement ingredients on this page reach Aspirin, Caffeine, Dihydrocodeine Bitartrate through this category.
Codeine 1 ingredient
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
1 of the supplement ingredient on this page reaches Aspirin, Caffeine, Dihydrocodeine Bitartrate through this category.
Cytochrome P450 1A2 (Cyp1A2) Substrates 1 ingredient
A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.
1 of the supplement ingredient on this page reaches Aspirin, Caffeine, Dihydrocodeine Bitartrate through this category.
Related: does Aspirin, Caffeine, Dihydrocodeine Bitartrate deplete any nutrients?
Aspirin, Caffeine, Dihydrocodeine Bitartrate has 5 reported nutrient associations in the research literature — see the Aspirin, Caffeine, Dihydrocodeine Bitartrate nutrient depletion report.
Take a Supplement Product? Check the Whole Bottle Against Aspirin, Caffeine, Dihydrocodeine Bitartrate
Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Aspirin, Caffeine, Dihydrocodeine Bitartrate.
Search a supplement product
Type a product name, brand, or UPC — smart search across our full catalog.
Grounded search over our product catalog — every verdict comes from our interaction database, never AI guesswork. How we use AI
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Photograph any Supplement Facts panel — we read the ingredients and check each one against your medications. Free, in seconds.
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Products that contain Aspirin, Caffeine, Dihydrocodeine Bitartrate-interacting ingredients
Real supplements from the NIH label database that contain the top interacting ingredients on this page — each one is worth a full label check before combining with Aspirin, Caffeine, Dihydrocodeine Bitartrate.
Aspirin, Caffeine, Dihydrocodeine Bitartrate & Supplements: Common Questions
What supplements interact with Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Which Aspirin, Caffeine, Dihydrocodeine Bitartrate supplement interactions are the most serious?
Can I take vitamins or supplements while on Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Do brands like Synalgos DC have the same supplement interactions as Aspirin, Caffeine, Dihydrocodeine Bitartrate?
Where do these interaction ratings come from?
Does Aspirin, Caffeine, Dihydrocodeine Bitartrate deplete any vitamins or nutrients?
What about Aspirin, Caffeine, Dihydrocodeine Bitartrate and my other medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Where This Data Comes From — and Why You Can Trust It
🧪 Licensed clinical database
Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.
🧑⚕️ Pharmacist review
This page is curated and coded by Dr. Brian Staiger, PharmD, BCPS, Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.
🔄 Kept current
Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 25, 2026.
🔍 Full transparency
How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.
Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.