Drug & supplement interaction

Ground Pine + Levothyroxine, Liothyronine

Levothyroxine, Liothyronine brand name: Armour Thyroid.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Ground Pine and Levothyroxine, Liothyronine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Ground Pine and Levothyroxine, Liothyronine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Levothyroxine, Liothyronine and Ground Pine in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Ground Pine at all — not against Levothyroxine, Liothyronine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Ground Pine safety at a glance

Ground Pine overall Use caution Little modern safety data exists, so use cautiously and only under guidance.
Pregnancy Avoid Traditionally linked to menstrual stimulation, so avoid during pregnancy.
Breastfeeding Avoid No safety data in breastfeeding, so it is best avoided.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Levothyroxine, Liothyronine and Ground Pine? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
Everything else you take

See Every Supplement That Interacts With Levothyroxine, Liothyronine

This page covers Ground Pine only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Levothyroxine, Liothyronine page lists 50 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Tiratricol (major), Acetyl-l-carnitine (moderate), Alpha-lipoic Acid (moderate) and Ascophyllum Nodosum (moderate).

By severity: 2 major · 39 moderate · 9 minor.

From our pharmacist’s overview on the Levothyroxine, Liothyronine page

“For anyone taking levothyroxine or liothyronine (Armour Thyroid), this list earns real caution, not just a passing glance. Most of these 50 ingredients pull in one of two directions.”

Reviewed by 2 · Jul 18, 2026

Open the Levothyroxine, Liothyronine interaction page

How much people look this up

Where Ground Pine and Levothyroxine, Liothyronine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Ground Pine
Top half

#692 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Levothyroxine, Liothyronine
Top 5%

#56 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Ground Pine is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Ground Pine reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Ground Pine and Levothyroxine, Liothyronine records this page draws on were last updated June 20, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Ground Pine

What is Ground Pine?

  • Joint pain and gout
  • Mild fever
  • Menstrual complaints
  • Wound and skin care
  • Digestive upset

Ground Pine (Ajuga chamaepitys) is a traditional European herb used mainly for joint pain, gout, and menstrual problems, but there is very little modern scientific evidence to support these uses. Because its safety has not been well studied, it should be used cautiously, and it should be avoided in pregnancy and breastfeeding. Talk to a pharmacist or doctor before trying it.

Ajuga chamaepitys · Lamiaceae · Aerial parts (flowering tops, leaves, and stems) · Dried herb, tea/infusion, tincture, liquid extract

An interaction check asks whether these two react with each other — it does not ask whether Ground Pine is a good idea for someone in your situation. Here is what our Ground Pine record says about it on its own.

Ground Pine: dosing

There is no established, standardized dose for Ground Pine. It has not been studied enough in modern research to define a safe and effective amount.If you choose to use a commercial product, follow the directions on the label and do not exceed them.

From our Ground Pine monograph — the full record covers uses, side effects and every documented interaction.

Read the full Ground Pine monograph & all interactions
Medication

About Levothyroxine, Liothyronine

Most-Reported Side Effects for Levothyroxine, Liothyronine

From FAERS, the FDA’s public side-effect reporting system (15 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 4 reports
Asthenia 3 reports
Dizziness 3 reports
Arthralgia 2 reports
Disorientation 2 reports
Keep checking

Other Drugs & Ground Pine

Browse every other medication we’ve checked against Ground Pine — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Ground Pine References

The 2 sources that drive our Ground Pine monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Ground Pine is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Herbs at a Glance — NIH National Center for Complementary and Integrative Health Source
  2. Herbs and Supplements — MedlinePlus (U.S. National Library of Medicine) Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Ground Pine and Levothyroxine, Liothyronine Together: Common Questions

Is it safe to take Ground Pine with Levothyroxine, Liothyronine?
We do not list a known interaction between Ground Pine and Levothyroxine, Liothyronine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Levothyroxine, Liothyronine interact with any supplements?
Yes. Levothyroxine, Liothyronine has documented interactions with 50 supplements in our database — Ground Pine is not one of them. The Levothyroxine, Liothyronine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Levothyroxine, Liothyronine and Ground Pine?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.