Drug & supplement interaction

Herb Robert + Clonidine

Clonidine brand name: Catapres.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Herb Robert and Clonidine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Herb Robert and Clonidine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Clonidine and Herb Robert in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Herb Robert at all — not against Clonidine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Herb Robert safety at a glance

Herb Robert overall Use caution Generally used in small amounts traditionally, but human safety data are very limited.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid No reliable safety data exist for nursing mothers, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Clonidine and Herb Robert? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Herb Robert and Clonidine May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • A skin rash Additional detail

    Herb Robert

    “There is currently a limited amount of information on the adverse effects of Herb Robert. Topically, Herb Robert has been reported to cause allergic contact dermatitis.”

    Herb Robert · Natural Medicines adverse-effect record, reported in dermatitis.

    2 sources cited
    1. 99144. Svendsen MT, Andersen KE, Thormann H, Paulsen E. Contact sensitization to Geranium robertianum L. in an amateur gardener. Contact Dermatitis. 2015;72(6):420-1.
    2. 99146. Badaoui A, Pecquet C, Fargeas C, Mahé E. Contact dermatitis caused by Geranium robertianum with erythema multiforme-like reaction. Contact Dermatitis. 2017;77(6):423-424.

    “Topically, Herb Robert can cause contact dermatitis. There are at least two cases of known contact sensitization of elderly individuals to Herb Robert through gardening. One case resulted in an erythema multiforme-like eruption requiring treatment with steroids.”

    Herb Robert · Natural Medicines adverse-effect record, reported in dermatitis.

    2 sources cited
    1. 99144. Svendsen MT, Andersen KE, Thormann H, Paulsen E. Contact sensitization to Geranium robertianum L. in an amateur gardener. Contact Dermatitis. 2015;72(6):420-1.
    2. 99146. Badaoui A, Pecquet C, Fargeas C, Mahé E. Contact dermatitis caused by Geranium robertianum with erythema multiforme-like reaction. Contact Dermatitis. 2017;77(6):423-424.

    Clonidine

    Listed in the ADVERSE REACTIONS section of the FDA label for Clonidine. Read the label on DailyMed ›

Reported for Herb Robert but not commonly for Clonidine: a severe skin reaction.

Effects for Clonidine come from the ADVERSE REACTIONS section of its FDA label; effects for Herb Robert come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 57,112 voluntary FDA FAERS reports for Clonidine that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

From our Q&A

Questions About Herb Robert or Clonidine

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Herb Robert or Clonidine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Clonidine

This page covers Herb Robert only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Clonidine page lists 138 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Tyramine (major) and Adrafinil (moderate).

By severity: 4 major · 113 moderate · 21 minor.

From our pharmacist’s overview on the Clonidine page

“American hellebore is the ingredient I would want a clonidine (Catapres) patient to know about first. Its alkaloids lower blood pressure even in small doses and slow the heart, both things clonidine already does, so the combination can drop someone dangerously low.”

Reviewed by 2 · Jul 18, 2026

Open the Clonidine interaction page

How much people look this up

Where Herb Robert and Clonidine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Herb Robert
Steady interest

#828 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Clonidine
Steady interest

#1,512 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Herb Robert reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Herb Robert and Clonidine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Herb Robert

What is Herb Robert?

Herb Robert
  • Digestive upset
  • Wound and skin care
  • Sore throat and mouth irritation
  • Respiratory complaints
  • General 'detox' tonic

Herb Robert is a traditional European herb used for digestion, wounds, and minor inflammation, but there is very little human research to confirm it works for any condition. It is likely fine in small amounts as a tea for most healthy adults, but its safety has not been well studied. Talk to your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Geranium robertianum · Geraniaceae · Above-ground parts (leaves, stems, and flowers) · Tea, tincture, dried herb, capsules, fresh poultice

An interaction check asks whether these two react with each other — it does not ask whether Herb Robert is a good idea for someone in your situation. Here is what our Herb Robert record says about it on its own.

Herb Robert: dosing

There is no established, standardized dose for Herb Robert. Traditional use involved brewing a small amount of the dried herb as a tea or applying crushed fresh leaves to the skin, but these amounts were not measured in a consistent, science-based way.If you choose to use a commercial product, follow the directions on the label and do not exceed the recommended amount.

From our Herb Robert monograph — the full record covers uses, side effects and every documented interaction.

Read the full Herb Robert monograph & all interactions
Medication

About Clonidine

What Is Clonidine Used For?

Brand name: Catapres

Clonidine is used to treat high blood pressure (hypertension). Several products — including Clonidine Hydrochloride tablets, Javadin oral solution, Nexiclon XR extended-release tablets, and Catapres-TTS skin patches — are approved for this use, either alone or combined with other blood pressure medicines.

Extended-release formulations — including Onyda XR oral suspension and clonidine hydrochloride extended-release tablets (such as Kapvay) — are approved to treat ADHD in children and teenagers ages 6 to 17, either on their own or alongside stimulant medications. Separately, clonidine injection products (Duraclon and others) are used alongside opioid pain medicines to treat severe cancer pain that opioids alone cannot control adequately.

Most-Reported Side Effects for Clonidine

From FAERS, the FDA’s public side-effect reporting system (57,112 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 3,519 reports
Nausea 3,475 reports
Headache 3,432 reports
Hypertension 3,275 reports
Dyspnea 2,748 reports
See full Clonidine drug information
Keep checking

Other Drugs & Herb Robert

Browse every other medication we’ve checked against Herb Robert — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Herb Robert against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Herb Robert list.

See the full Herb Robert interactions page
See every supplement checked against Clonidine, ranked by severity
Evidence & sources

Herb Robert References

The 3 references that drive our Herb Robert monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Svendsen MT, Andersen KE, Thormann H, Paulsen E. Contact sensitization to Geranium robertianum L. in an amateur gardener. Contact Dermatitis. 2015;72(6):420-1.
  2. Panahi Y, Akhavan A, Sahebkar A, et al. Investigation of the effectiveness of Syzygium aromaticum, Lavandula angustifolia and Geranium robertianum essential oils in the treatment of acute external otitis: a comparative trial with ciprofloxacin. J Microbi PubMed
  3. Badaoui A, Pecquet C, Fargeas C, Mahé E. Contact dermatitis caused by Geranium robertianum with erythema multiforme-like reaction. Contact Dermatitis. 2017;77(6):423-424.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Herb Robert and Clonidine Together: Common Questions

Is it safe to take Herb Robert with Clonidine?
We do not list a known interaction between Herb Robert and Clonidine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Herb Robert and Clonidine have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Clonidine interact with any supplements?
Yes. Clonidine has documented interactions with 138 supplements in our database — Herb Robert is not one of them. The Clonidine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Herb Robert monograph Uses, safety profile, and every drug interaction in one place Clonidine drug information The full plain-English guide to this medication Clonidine supplement interactions Every supplement checked against Clonidine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Clonidine and Herb Robert?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.