Drug & supplement interaction

Korean Pine + Opium Tincture

Opium Tincture brand name: Paregoric.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Korean Pine and Opium Tincture in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Korean Pine and Opium Tincture

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Opium Tincture and Korean Pine in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Korean Pine safety at a glance

Korean Pine overall Use caution The nuts and oil are generally safe as food, but concentrated supplements are less studied.
Pregnancy Use caution Pine nuts as food are fine, but concentrated extracts have not been well studied, so avoid these.
Breastfeeding Use caution Food amounts are likely fine, but safety of supplements is unknown, so use caution.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Opium Tincture and Korean Pine? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Opium Tincture

Interactions in our licensed database are recorded against drug classes, not just single drug names. Opium Tincture is filed under 4 classifications — including narcotic drugs, cns depressants, seizure threshold lowering drugs. Korean Pine has documented interactions with 1 drug class — the most serious being antihypertensive drugs (moderate) — and none of Opium Tincture’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Korean Pine Does Interact With Other Medications

Korean Pine has 172 moderate known drug interactions in our database — Opium Tincture isn’t one of them. If you take anything else, check it against the full list below.

Moderate 172 No known interaction 2,658 (incl. Opium Tincture)
Taking anything else?

Check Another of Your Medications Against Korean Pine

Covers the 2,830 medications we’ve checked against Korean Pine. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Opium Tincture

This page covers Korean Pine only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Opium Tincture page lists 100 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Kava (major).

By severity: 7 major · 78 moderate · 15 minor.

From our pharmacist’s overview on the Opium Tincture page

“Opium tincture (Paregoric) is an opioid, prescribed mainly for severe diarrhea, and like any opioid it slows the brain and breathing. That is why 78 of the 100 supplement ingredients on this page interact by adding sedation, and why the seven rated major, alcohol and kava among them, deserve your attention before the rest.”

Reviewed by 2 · Jul 18, 2026

Open the Opium Tincture interaction page

One more smart check

Taking Korean Pine as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing Korean Pine, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Korean Pine. Even though Korean Pine itself has no known interaction with Opium Tincture, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Korean Pine and Opium Tincture Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Korean Pine
Steady interest

#834 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Opium Tincture
Steady interest

#2,564 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Korean Pine reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Korean Pine and Opium Tincture records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Korean Pine

What is Korean Pine?

  • Appetite control and weight management
  • Heart and cholesterol health
  • General nutrition and energy
  • Skin and antioxidant support
  • Cough and respiratory comfort (traditional)

Korean Pine is best known as the source of edible pine nuts and pine nut oil, which are nutritious foods rich in healthy fats. While some early research looks at pine nut oil for appetite and cholesterol, strong human evidence for any specific health benefit is limited. Treat it mainly as a food, and check with your pharmacist or doctor before using concentrated extracts.

Pinus koraiensis · Pinaceae · Seeds (pine nuts), seed oil, nuts, bark, and needles · Pine nuts (food), pine nut oil (capsules or liquid), needle tea, extracts

An interaction check asks whether these two react with each other — it does not ask whether Korean Pine is a good idea for someone in your situation. Here is what our Korean Pine record says about it on its own.

Korean Pine: dosing

There is no established standard medicinal dose for Korean Pine or pine nut oil. As a food, pine nuts are simply eaten in normal amounts as part of meals.For pine nut oil capsules or extracts, follow the directions on the product label, since strength varies between products.

From our Korean Pine monograph — the full record covers uses, side effects and every documented interaction.

Read the full Korean Pine monograph & all interactions
Medication

About Paregoric

What Is Paregoric Used For?

Brand name: Paregoric

  • Paregoric is used to relieve diarrhea. It decreases stomach and intestinal movement in the digestive system.

  • This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

See full Paregoric drug information
Keep checking

Other Drugs & Korean Pine

Browse every other medication we’ve checked against Korean Pine — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
172Moderate
0Minor
2,657No known interaction
172 Moderate 2,657 No interaction
Moderate

172 interactions

Showing 60 of 172 moderate interactions — see all 172 on the Korean Pine page.

No interaction 2,657 drugs checked — show the list

We also checked Korean Pine against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,657 medications checked with no known interaction — see the full Korean Pine list.

See the full Korean Pine interactions page
See every supplement checked against Opium Tincture, ranked by severity
Evidence & sources

Korean Pine References

The 2 references that drive our Korean Pine monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Sugano M, Ikeda I, Wakamatsu K, Oka T. Influence of Korean pine (Pinus koraiensis)-seed oil containing cis-5,cis-9,cis-12-octadecatrienoic acid on polyunsaturated fatty acid metabolism, eicosanoid production and blood pressure of rats. Br J Nutr 1994;72(5
  2. Lee H, Kim H, Choue R, Lim H. Evaluation of the Effects of Pinus koraiensis Needle Extracts on Serum Lipid and Oxidative Stress in Adults with Borderline Dyslipidemia: A Randomized, Double-Blind, and Placebo-Controlled Clinical Trial. Evid Based Complemen

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Korean Pine and Opium Tincture Together: Common Questions

Is it safe to take Korean Pine with Opium Tincture?
We do not list a known interaction between Korean Pine and Opium Tincture. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Korean Pine and Opium Tincture combination checked?
Interactions in our licensed database are recorded against drug classes. Opium Tincture is filed under 4 classifications, and Korean Pine has documented interactions with 1 drug class — none of Opium Tincture's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Korean Pine interact with any other medications?
Yes. Korean Pine has 172 documented drug interactions in our database — Opium Tincture is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Opium Tincture interact with any supplements?
Yes. Opium Tincture has documented interactions with 100 supplements in our database — Korean Pine is not one of them. The Opium Tincture interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Korean Pine monograph Uses, safety profile, and every drug interaction in one place Paregoric drug information The full plain-English guide to this medication Opium Tincture supplement interactions Every supplement checked against Opium Tincture, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Opium Tincture and Korean Pine?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.