Drug & supplement interaction

Korean Pine + Rosuvastatin

Rosuvastatin brand names: Crestor, Ezallor.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Korean Pine and Rosuvastatin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Korean Pine and Rosuvastatin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Rosuvastatin and Korean Pine in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Korean Pine safety at a glance

Korean Pine overall Use caution The nuts and oil are generally safe as food, but concentrated supplements are less studied.
Pregnancy Use caution Pine nuts as food are fine, but concentrated extracts have not been well studied, so avoid these.
Breastfeeding Use caution Food amounts are likely fine, but safety of supplements is unknown, so use caution.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Rosuvastatin and Korean Pine? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Rosuvastatin

Interactions in our licensed database are recorded against drug classes, not just single drug names. Rosuvastatin is filed under 4 classifications — including hmg-coa reductase inhibitors ("statins"), hepatotoxic drugs, oral drugs. Korean Pine has documented interactions with 1 drug class — the most serious being antihypertensive drugs (moderate) — and none of Rosuvastatin’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Korean Pine Does Interact With Other Medications

Korean Pine has 172 moderate known drug interactions in our database — Rosuvastatin isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Korean Pine

Covers the 2,830 medications we’ve checked against Korean Pine. Pick one to open its full report.

What to actually watch for

What Rosuvastatin’s Own FDA Label Lists

This is not an interaction — none of it involves Korean Pine. These are the most notable effects listed in the ADVERSE REACTIONS section of Rosuvastatin’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • A change in thyroid levels Worth acting on
  • Severe muscle breakdown Worth acting on
  • Muscle weakness Worth acting on
  • Memory problems Worth acting on
  • Pancreatitis Worth acting on
  • Yellowing of the skin or eyes Worth acting on
  • High blood sugar Worth acting on
  • Confusion Worth acting on
  • A severe skin reaction Worth acting on
  • Low mood Worth acting on

Showing the 10 most notable of 30 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Rosuvastatin. Read the label on DailyMed › Where a percentage is shown, it is the share of 223,851 voluntary FDA FAERS reports for Rosuvastatin that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Korean Pine’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Korean Pine side to compare — that is a limit of the record, not a statement that Korean Pine has no side effects.

Overlapping uses

What Rosuvastatin Is Prescribed For, and What Korean Pine Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Rosuvastatin is a prescription medicine with approved uses on its FDA label. Korean Pine is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Rosuvastatin is prescribed for: Rosuvastatin lowers cholesterol and other blood fats. It is used with a healthy diet in adults for high cholesterol (primary hyperlipidemia), mixed dyslipidemia, high triglycerides (hypertriglyceridemia) and primary dysbetalipoproteinemia (a less common cholesterol disorder). It is also used for familial hypercholesterolemia, an inherited form of very high cholesterol. Some tablet labels cover children 8 and older with the heterozygous form.

Read the rest of what Rosuvastatin is prescribed for

Other labels also cover the homozygous form in children 7 and older, but one generic tablet label leaves out the pediatric information. Several tablet labels include slowing atherosclerosis (fatty plaque buildup in arteries) and lowering the risk of heart attack, stroke and arterial revascularization procedures in adults at increased cardiovascular risk. Wording varies by product.

Korean Pine has been studied for:

  • Dyslipidemia studied, not established Korean Pine has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Korean Pine for dyslipidemia

    A small clinical study in people with mild dyslipidemia (total cholesterol 200-239 mg/dL) shows that taking an extract of Korean pine needles 600 mg orally twice daily for 12 weeks does not significantly improve levels of any serum lipid.

    1 source cited
    1. 97259. Lee H, Kim H, Choue R, Lim H. Evaluation of the Effects of Pinus koraiensis Needle Extracts on Serum Lipid and Oxidative Stress in Adults with Borderline Dyslipidemia: A Randomized, Double-Blind, and Placebo-Controlled Clinical Trial. Evid Based Complemen

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Rosuvastatin on your own; if you are taking Korean Pine for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Korean Pine or Rosuvastatin

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Korean Pine or Rosuvastatin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Rosuvastatin

This page covers Korean Pine only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Rosuvastatin page lists 63 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Grapefruit (major), Siberian Cocklebur (major) and Wine (major).

By severity: 5 major · 48 moderate · 10 minor.

From our pharmacist’s overview on the Rosuvastatin page

“Rosuvastatin (Crestor, Ezallor) is a statin taken daily for years to lower cholesterol, and its supplement list deserves real scrutiny, not a quick skim. Five of the 63 ingredients on file carry a major rating, headed by grapefruit, which can raise statin blood levels, and by heavy drinking, since beer and wine compound the strain this…”

Reviewed by 2 · Jul 18, 2026

Open the Rosuvastatin interaction page

One more smart check

Taking Korean Pine as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing Korean Pine, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Korean Pine. Even though Korean Pine itself has no known interaction with Rosuvastatin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Korean Pine and Rosuvastatin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Korean Pine
Top half

#668 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Rosuvastatin
Top 1%

#14 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Korean Pine reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Korean Pine and Rosuvastatin records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Korean Pine

What is Korean Pine?

  • Appetite control and weight management
  • Heart and cholesterol health
  • General nutrition and energy
  • Skin and antioxidant support
  • Cough and respiratory comfort (traditional)

Korean Pine is best known as the source of edible pine nuts and pine nut oil, which are nutritious foods rich in healthy fats. While some early research looks at pine nut oil for appetite and cholesterol, strong human evidence for any specific health benefit is limited. Treat it mainly as a food, and check with your pharmacist or doctor before using concentrated extracts.

Pinus koraiensis · Pinaceae · Seeds (pine nuts), seed oil, nuts, bark, and needles · Pine nuts (food), pine nut oil (capsules or liquid), needle tea, extracts

An interaction check asks whether these two react with each other — it does not ask whether Korean Pine is a good idea for someone in your situation. Here is what our Korean Pine record says about it on its own.

Korean Pine: dosing

There is no established standard medicinal dose for Korean Pine or pine nut oil. As a food, pine nuts are simply eaten in normal amounts as part of meals.For pine nut oil capsules or extracts, follow the directions on the product label, since strength varies between products.

From our Korean Pine monograph — the full record covers uses, side effects and every documented interaction.

Read the full Korean Pine monograph & all interactions
Medication

About Rosuvastatin

What Is Rosuvastatin Used For?

Brand names: Crestor, Ezallor

Rosuvastatin lowers cholesterol and other blood fats. It is used with a healthy diet in adults for high cholesterol (primary hyperlipidemia), mixed dyslipidemia, high triglycerides (hypertriglyceridemia) and primary dysbetalipoproteinemia (a less common cholesterol disorder).

It is also used for familial hypercholesterolemia, an inherited form of very high cholesterol. Some tablet labels cover children 8 and older with the heterozygous form. Other labels also cover the homozygous form in children 7 and older, but one generic tablet label leaves out the pediatric information. Several tablet labels include slowing atherosclerosis (fatty plaque buildup in arteries) and lowering the risk of heart attack, stroke and arterial revascularization procedures in adults at increased cardiovascular risk. Wording varies by product.

See full Rosuvastatin drug information
Keep checking

Other Drugs & Korean Pine

Browse every other medication we’ve checked against Korean Pine — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
172Moderate
0Minor
2,657No known interaction
Moderate

172 interactions

Showing 60 of 172 moderate interactions — see all 172 on the Korean Pine page.

No interaction 2,657 drugs checked — show the list
Evidence & sources

Korean Pine References

The 2 references that drive our Korean Pine monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Sugano M, Ikeda I, Wakamatsu K, Oka T. Influence of Korean pine (Pinus koraiensis)-seed oil containing cis-5,cis-9,cis-12-octadecatrienoic acid on polyunsaturated fatty acid metabolism, eicosanoid production and blood pressure of rats. Br J Nutr 1994;72(5
  2. Lee H, Kim H, Choue R, Lim H. Evaluation of the Effects of Pinus koraiensis Needle Extracts on Serum Lipid and Oxidative Stress in Adults with Borderline Dyslipidemia: A Randomized, Double-Blind, and Placebo-Controlled Clinical Trial. Evid Based Complemen

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Korean Pine and Rosuvastatin Together: Common Questions

Is it safe to take Korean Pine with Rosuvastatin?
We do not list a known interaction between Korean Pine and Rosuvastatin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Korean Pine and Rosuvastatin used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Korean Pine in each. That is a conversation for your prescriber, especially if Rosuvastatin is being adjusted to a target.
How was the Korean Pine and Rosuvastatin combination checked?
Interactions in our licensed database are recorded against drug classes. Rosuvastatin is filed under 4 classifications, and Korean Pine has documented interactions with 1 drug class — none of Rosuvastatin's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Korean Pine interact with any other medications?
Yes. Korean Pine has 172 documented drug interactions in our database — Rosuvastatin is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Rosuvastatin interact with any supplements?
Yes. Rosuvastatin has documented interactions with 63 supplements in our database — Korean Pine is not one of them. The Rosuvastatin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Rosuvastatin and Korean Pine?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.