Drug & supplement interaction

L-cysteine + Liraglutide

Liraglutide brand name: Victoza.

Moderate Interaction
Medically reviewed by · Updated September 2026
The bottom line Moderate

L-cysteine has a moderate interaction with Liraglutide. Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.

Read the full interaction report
SeverityModerate
LikelihoodPossible
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

L-cysteine and Liraglutide

Here is the interaction we found between these two, with the evidence behind it.

Moderate

ANTIDIABETES DRUGS

Why this applies to Liraglutide

Liraglutide falls under ANTIDIABETES DRUGS — the group L-cysteine interacts with.

Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that L-cysteine can have hypoglycemic effects.
Severity Moderate Likelihood Possible Evidence D

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the gist: liraglutide (Victoza) already works to lower your blood sugar. In some lab and animal studies, L-cysteine has shown its own mild blood-sugar-lowering effect. So the concern is simply additive. If you stack a supplement that nudges sugar down on top of a medication that does the same job, your levels could theoretically dip too low.

Honestly, this is a theoretical worry based only on animal research, not human studies, so I wouldn't lose sleep over it. Still, it's worth knowing the signs of low blood sugar (shakiness, sweating, dizziness, confusion, sudden hunger). Liraglutide alone rarely causes that, but pay attention if you add cysteine. Please check with your pharmacist or doctor before starting it, and keep monitoring your numbers.

Contact Dr. Brian directly if you have additional questions on this interaction
References
  1. Lee S, Han KH, Nakamura Y, et al. Dietary L-cysteine improves the antioxidative potential and lipid metabolism in rats fed a normal diet. Biosci Biotechnol Biochem 2013;77(7):1430-4.

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

L-cysteine Also Interacts With Other Medications

L-cysteine has 85 moderate known drug interactions in our database — the Liraglutide one above is one of them. If you take anything else, check it against the full list below.

Moderate 85 No known interaction 2,745 (incl. Liraglutide)
Taking anything else?

Check Another of Your Medications Against L-cysteine

Covers the 2,830 medications we’ve checked against L-cysteine. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Liraglutide

This page covers L-cysteine only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Liraglutide page lists 239 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Siberian Cocklebur (major), Acai (moderate), African Wild Potato (moderate), Agaricus Mushroom (moderate) and Agmatine (moderate).

By severity: 1 major · 208 moderate · 30 minor.

From our pharmacist’s overview on the Liraglutide page

“If you take liraglutide (Victoza), the ingredient to know first is Siberian cocklebur, the only major-rated interaction of the 239 on this page. Its seeds have caused severe hypoglycemia in people, dangerously low blood sugar, and liraglutide already pushes glucose down.”

Reviewed by 2 · Jul 18, 2026

Open the Liraglutide interaction page

One more smart check

Taking L-cysteine as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing L-cysteine, each one broken down to its full ingredient list — and combination products often carry several ingredients besides L-cysteine. Your product may carry other ingredients that interact with Liraglutide too, on top of L-cysteine — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where L-cysteine and Liraglutide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement L-cysteine
Steady interest

#798 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Liraglutide
Top half

#1,334 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About L-cysteine

What is L-cysteine?

  • Antioxidant support
  • Skin and hair health
  • Liver support
  • Respiratory and mucus thinning
  • General protein/amino acid supplementation

L-cysteine is a sulfur-containing amino acid your body uses to make proteins and the antioxidant glutathione. Most people get enough from food, and supplements are usually well tolerated, but strong evidence supporting specific health benefits from extra L-cysteine is limited. Talk to your pharmacist or doctor before starting it, especially if you are pregnant, breastfeeding, or have a health condition.

Read the full L-cysteine monograph & all interactions
Medication

About Liraglutide Injection

What Is Liraglutide Injection Used For?

Brand name: Victoza

The label text provided describes Saxenda (liraglutide injection) for chronic weight management. It is used along with a reduced-calorie diet and more physical activity.

Saxenda is for adults with obesity (BMI 30 or higher), or overweight (BMI 27 or higher) with at least one weight-related condition such as high blood pressure, type 2 diabetes or abnormal cholesterol/fats (dyslipidemia). It is also for children 12 and older who weigh over 60 kg and have obesity by pediatric BMI cut-offs.

See full Liraglutide Injection drug information
Keep checking

Other Drugs & L-cysteine

Browse every other medication we’ve checked against L-cysteine — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
85Moderate
0Minor
2,744No known interaction
85 Moderate 2,744 No interaction
Moderate

85 interactions

Showing 60 of 85 moderate interactions — see all 85 on the L-cysteine page.

No interaction 2,744 drugs checked — show the list

We also checked L-cysteine against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,744 medications checked with no known interaction — see the full L-cysteine list.

See the full L-cysteine interactions page
See every supplement checked against Liraglutide, ranked by severity
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
L-cysteine monograph › Uses, safety, and every drug interaction in one place Liraglutide supplement interactions › Every supplement checked against Liraglutide, ranked by severity Liraglutide Injection drug information › The full plain-English guide to this medication Supplement interaction checker › Check any supplement or product against your medications Browse medications A–Z › Every drug we've checked against herbs & supplements Ask a pharmacist › Free, personal answer from our licensed team
Pharmacist Counseling Corner

Taking L-cysteine and Liraglutide Together: Common Questions

Can you take L-cysteine with Liraglutide?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the L-cysteine and Liraglutide interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Liraglutide and L-cysteine?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.