Drug & supplement interaction

Lactobacillus Jensenii + Hydrocodone, Pseudoephedrine

Hydrocodone, Pseudoephedrine brand names: P-V-Tussin, Rezira.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Lactobacillus Jensenii and Hydrocodone, Pseudoephedrine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Lactobacillus Jensenii and Hydrocodone, Pseudoephedrine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Hydrocodone, Pseudoephedrine and Lactobacillus Jensenii in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Lactobacillus Jensenii safety at a glance

Lactobacillus Jens... overall Use caution Generally considered low risk for healthy people, but supplement evidence is limited and quality varies.
Pregnancy Use caution Not well studied as a supplement in pregnancy; speak with your doctor before using.
Breastfeeding Use caution Little safety data exists for use while breastfeeding; check with your doctor first.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Hydrocodone, Pseudoephedrine and Lactobacillus Jensenii? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Hydrocodone, Pseudoephedrine

Interactions in our licensed database are recorded against drug classes, not just single drug names. Hydrocodone, Pseudoephedrine is filed under 9 classifications — including narcotic drugs, alpha-adrenergic agonists, stimulant drugs. Lactobacillus Jensenii has documented interactions with 1 drug class — the most serious being antibiotic drugs (moderate) — and none of Hydrocodone, Pseudoephedrine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Lactobacillus Jensenii Does Interact With Other Medications

Lactobacillus Jensenii has 182 moderate known drug interactions in our database — Hydrocodone, Pseudoephedrine isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Lactobacillus Jensenii

Covers the 2,830 medications we’ve checked against Lactobacillus Jensenii. Pick one to open its full report.

What to actually watch for

What Lactobacillus Jensenii Itself Has Been Linked To

This is not an interaction — nothing below involves Hydrocodone, Pseudoephedrine. It is the side-effect record for Lactobacillus Jensenii on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Lactobacillus Jensenii, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • A higher chance of infection Worth acting on Additional detail

    “Since Lactobacillus jensenii preparations contain live and active microorganisms, there is some concern that they might cause pathogenic infection in some patients. L. jensenii has been isolated in cases of bacteremia, sepsis, prostate abscess, perinephric abscess, endocarditis, and pulmonary septic emboli.”

    Lactobacillus Jensenii · Natural Medicines adverse-effect record, reported in sepsis.

    5 sources cited
    1. 107543. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
    2. 110917. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
    3. 110918. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
    4. 110920. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
    5. 110921. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.

Everything above comes from the Natural Medicines adverse-effect record for Lactobacillus Jensenii — expand a row for the licensed statement it rests on. We haven’t matched Hydrocodone, Pseudoephedrine to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Hydrocodone, Pseudoephedrine.

Everything else you take

See Every Supplement That Interacts With Hydrocodone, Pseudoephedrine

This page covers Lactobacillus Jensenii only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Hydrocodone, Pseudoephedrine page lists 241 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Ephedra (major) and Gamma-hydroxybutyrate (ghb) (major).

By severity: 13 major · 190 moderate · 38 minor.

From our pharmacist’s overview on the Hydrocodone, Pseudoephedrine page

“Rezira and P-V-Tussin pair hydrocodone, an opioid, with pseudoephedrine, a decongestant, so the 241 supplements here pull in two directions and I would handle this combination with real care. Most entries either deepen the opioid's sedation (78 ingredients are CNS depressants, alcohol included) or stack stimulant effects onto the pseud…”

Reviewed by 2 · Jul 18, 2026

Open the Hydrocodone, Pseudoephedrine interaction page

How much people look this up

Where Lactobacillus Jensenii and Hydrocodone, Pseudoephedrine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Lactobacillus Jensenii
Top half

#488 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Hydrocodone, Pseudoephedrine
Top 25%

#291 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Lactobacillus Jensenii reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Lactobacillus Jensenii and Hydrocodone, Pseudoephedrine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Lactobacillus Jensenii

What is Lactobacillus Jensenii?

  • Vaginal health
  • Maintaining healthy vaginal flora
  • Bacterial vaginosis support
  • Yeast infection support
  • General probiotic use

Lactobacillus jensenii is one of the natural 'good' bacteria found in a healthy vagina, and it is sometimes added to probiotic products marketed for vaginal health. While its role in the body is well recognized, there is only limited human research on taking it as a supplement, so the benefits are not proven. Talk with your pharmacist or doctor before using it, especially if you have a weakened immune system.

Lactobacillus jensenii · Lactobacillaceae · Whole live bacteria (probiotic strain) · Capsules, vaginal suppositories, multi-strain probiotic blends, powders

An interaction check asks whether these two react with each other — it does not ask whether Lactobacillus Jensenii is a good idea for someone in your situation. Here is what our Lactobacillus Jensenii record says about it on its own.

Lactobacillus Jensenii: dosing

There is no official or standardized dose for Lactobacillus jensenii. Probiotic amounts are often measured in colony-forming units (CFUs), and products vary widely.The best approach is to follow the directions on the product label and not exceed the recommended amount.

From our Lactobacillus Jensenii monograph — the full record covers uses, side effects and every documented interaction.

Read the full Lactobacillus Jensenii monograph & all interactions
Keep checking

Other Drugs & Lactobacillus Jensenii

Browse every other medication we’ve checked against Lactobacillus Jensenii — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
182Moderate
0Minor
2,647No known interaction
Moderate

182 interactions

Showing 60 of 182 moderate interactions — see all 182 on the Lactobacillus Jensenii page.

No interaction 2,647 drugs checked — show the list
Evidence & sources

Lactobacillus Jensenii References

The 6 references that drive our Lactobacillus Jensenii monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  3. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  4. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  5. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  6. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Lactobacillus Jensenii and Hydrocodone, Pseudoephedrine Together: Common Questions

Is it safe to take Lactobacillus Jensenii with Hydrocodone, Pseudoephedrine?
We do not list a known interaction between Lactobacillus Jensenii and Hydrocodone, Pseudoephedrine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Lactobacillus Jensenii and Hydrocodone, Pseudoephedrine combination checked?
Interactions in our licensed database are recorded against drug classes. Hydrocodone, Pseudoephedrine is filed under 9 classifications, and Lactobacillus Jensenii has documented interactions with 1 drug class — none of Hydrocodone, Pseudoephedrine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Lactobacillus Jensenii interact with any other medications?
Yes. Lactobacillus Jensenii has 182 documented drug interactions in our database — Hydrocodone, Pseudoephedrine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Hydrocodone, Pseudoephedrine interact with any supplements?
Yes. Hydrocodone, Pseudoephedrine has documented interactions with 241 supplements in our database — Lactobacillus Jensenii is not one of them. The Hydrocodone, Pseudoephedrine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Hydrocodone, Pseudoephedrine and Lactobacillus Jensenii?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.