Drug & supplement interaction

Lady's Bedstraw + Perphenazine

Perphenazine brand name: Trilafon.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated June 2026 · Pair last verified Sep 20, 2026

The bottom line No known interaction

We found no known interaction between Lady's Bedstraw and Perphenazine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Lady's Bedstraw and Perphenazine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Perphenazine and Lady's Bedstraw in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Lady's Bedstraw at all — not against Perphenazine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Lady's Bedstraw safety at a glance

Lady's Bedstraw overall Use caution Generally considered mild in food-like amounts, but human safety data are very limited.

Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.

Breastfeeding Avoid No reliable safety data, so avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Perphenazine and Lady's Bedstraw? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

What to actually watch for

What Perphenazine’s Own FDA Label Lists

This is not an interaction — none of it involves Lady's Bedstraw. These are the most notable effects listed in the ADVERSE REACTIONS section of Perphenazine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

A bowel blockage Worth acting on
Muscle weakness Worth acting on
Trouble swallowing Worth acting on
Trouble passing urine Worth acting on
Unsteadiness Worth acting on
Low blood sugar Worth acting on
A slow heartbeat Worth acting on
Yellowing of the skin or eyes Worth acting on
High blood sugar Worth acting on
Wheezing Worth acting on

Showing the 10 most notable of 50 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Perphenazine. Read the label on DailyMed › Lady's Bedstraw’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Lady's Bedstraw side to compare — that is a limit of the record, not a statement that Lady's Bedstraw has no side effects.

Everything else you take

See Every Supplement That Interacts With Perphenazine

This page covers Lady's Bedstraw only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Perphenazine page lists 147 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Henbane (major), Indian Snakeroot (major), Rauvolfia Vomitoria (major) and Scopolia (major).

By severity: 5 major · 108 moderate · 34 minor.

From our pharmacist’s overview on the Perphenazine page

“Perphenazine (Trilafon) treats schizophrenia and severe nausea, and this list deserves real care. Five of the 147 ingredients on file rate major, and those five are the ones to understand first.”

Reviewed by 2 · Jul 18, 2026

Open the Perphenazine interaction page

How much people look this up

Where Lady's Bedstraw and Perphenazine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Lady's Bedstraw

Steady interest

#1,299 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Perphenazine

Steady interest

#2,250 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Lady's Bedstraw is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Lady's Bedstraw reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Lady's Bedstraw and Perphenazine records this page draws on were last updated June 22, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Lady's Bedstraw

What is Lady's Bedstraw?

Urinary and mild diuretic support
Skin complaints (topical)
Mild calming/sleep support
Digestive upset
Wound and inflammation soothing

Lady's bedstraw is a traditional European herb taken mostly as a tea for urinary, skin, and mild calming purposes. High-quality human research is lacking, so its benefits are not well proven, and you should talk with a pharmacist or doctor before using it—especially during pregnancy or breastfeeding.

Galium verum · Rubiaceae · Aerial parts (flowering tops, leaves, and stems) · Tea, infusion, tincture, dried herb, topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Lady's Bedstraw is a good idea for someone in your situation. Here is what our Lady's Bedstraw record says about it on its own.

Lady's Bedstraw: dosing

There is no established or standardized dose for lady's bedstraw. Traditional use involves a tea made from the dried aerial parts, but exact safe and effective amounts have not been determined by research.If you choose to use a commercial product, follow the directions on the label and do not exceed them.

From our Lady's Bedstraw monograph — the full record covers uses, side effects and every documented interaction.

Read the full Lady's Bedstraw monograph & all interactions

Medication

About Perphenazine

What Is Perphenazine Used For?

Brand name: Trilafon

Perphenazine tablets are approved to treat schizophrenia in adults. They are also used to control severe nausea and vomiting in adults when other measures are not enough.

Perphenazine has not been shown effective for managing behavioral problems in patients with intellectual disabilities, and it is not approved for dementia-related psychosis in elderly patients.

See full Perphenazine drug information

Keep checking

Other Drugs & Lady's Bedstraw

Browse every other medication we’ve checked against Lady's Bedstraw — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

0Moderate

0Minor

2,829No known interaction

2,829 No interaction

No interaction 2,829 drugs checked — show the list

We also checked Lady's Bedstraw against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Lady's Bedstraw list.

See the full Lady's Bedstraw interactions page

See every supplement checked against Perphenazine, ranked by severity

Evidence & sources

Lady's Bedstraw References

The 2 sources that drive our Lady's Bedstraw monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Lady's Bedstraw is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

Herbs at a Glance — NIH National Center for Complementary and Integrative Health (NCCIH) Source
Herbs and Supplements — MedlinePlus (U.S. National Library of Medicine) Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Lady's Bedstraw and Perphenazine Together: Common Questions

Is it safe to take Lady's Bedstraw with Perphenazine?

We do not list a known interaction between Lady's Bedstraw and Perphenazine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Does Perphenazine interact with any supplements?

Yes. Perphenazine has documented interactions with 147 supplements in our database — Lady's Bedstraw is not one of them. The Perphenazine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Lady's Bedstraw monograph Uses, safety profile, and every drug interaction in one place Perphenazine drug information The full plain-English guide to this medication Perphenazine supplement interactions Every supplement checked against Perphenazine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Perphenazine and Lady's Bedstraw?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.