Drug & supplement interaction

Maidenhair Fern + Testosterone Enanthate

Testosterone Enanthate brand name: Xyosted.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Maidenhair Fern and Testosterone Enanthate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Maidenhair Fern and Testosterone Enanthate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Testosterone Enanthate and Maidenhair Fern in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Maidenhair Fern at all — not against Testosterone Enanthate, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Maidenhair Fern safety at a glance

Maidenhair Fern overall Use caution Used traditionally in foods and teas, but modern safety data in humans are limited.
Pregnancy Unsafe When used orally. Maidenhair fern is contraindicated in pregnancy. Read the full pregnancy detail
Breastfeeding Avoid There is not enough safety information, so it is best avoided while breastfeeding.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Testosterone Enanthate and Maidenhair Fern? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Testosterone Enanthate’s Own FDA Label Lists

This is not an interaction — none of it involves Maidenhair Fern. These are the most notable effects listed in the ADVERSE REACTIONS section of Testosterone Enanthate’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Kidney stones Worth acting on
  • Hearing loss Worth acting on
  • A stroke or mini-stroke Worth acting on
  • Bone thinning Worth acting on
  • Pain or burning when passing urine Worth acting on
  • Low blood sugar Worth acting on
  • A heart attack Worth acting on
  • Blood clots Worth acting on
  • Hallucinations Worth acting on
  • Yellowing of the skin or eyes Worth acting on

Showing the 10 most notable of 54 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Testosterone Enanthate. Read the label on DailyMed › Where a percentage is shown, it is the share of 1,589 voluntary FDA FAERS reports for Testosterone Enanthate that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Maidenhair Fern’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Maidenhair Fern side to compare — that is a limit of the record, not a statement that Maidenhair Fern has no side effects.

Special populations

Maidenhair Fern in Pregnancy & Breastfeeding

Pregnancy Unsafe

When used orally. Maidenhair fern is contraindicated in pregnancy.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

From our Q&A

Questions About Maidenhair Fern or Testosterone Enanthate

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Maidenhair Fern or Testosterone Enanthate, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Testosterone Enanthate

This page covers Maidenhair Fern only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Testosterone Enanthate page lists 184 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Grapefruit (major), Siberian Cocklebur (major) and St. John's Wort (major).

By severity: 6 major · 134 moderate · 44 minor.

From our pharmacist’s overview on the Testosterone Enanthate page

“Beer and wine both carry major ratings on this list, because heavy alcohol use can compound the strain testosterone enanthate (Xyosted) already places on the liver. That liver theme runs through 38 of the 184 ingredients on file, Siberian cocklebur among them, and with six interactions rated major overall, this page deserves genuine ca…”

Reviewed by 2 · Jul 18, 2026

Open the Testosterone Enanthate interaction page

One more smart check

Taking Maidenhair Fern as Part of a Dietary Supplement Product? Check It for Interactions

We hold 18 real supplement products containing Maidenhair Fern, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Maidenhair Fern. Even though Maidenhair Fern itself has no known interaction with Testosterone Enanthate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Maidenhair Fern and Testosterone Enanthate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Maidenhair Fern
Steady interest

#1,266 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Testosterone Enanthate
Steady interest

#1,422 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Maidenhair Fern reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Maidenhair Fern and Testosterone Enanthate records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Maidenhair Fern

What is Maidenhair Fern?

  • Cough and respiratory complaints
  • Hair and scalp health
  • Cold and flu symptoms
  • Mild urinary complaints
  • Menstrual complaints

Maidenhair fern is a traditional herb used mainly in teas and syrups for coughs and respiratory complaints, but high-quality human studies are lacking. Because its safety has not been well studied, it is best to use it cautiously and to avoid it during pregnancy and breastfeeding.

Adiantum capillus-veneris · Pteridaceae · Fronds (leaves) and the whole above-ground plant · Tea (infusion), syrup, dried herb, liquid extract, and as an ingredient in traditional cough preparations

An interaction check asks whether these two react with each other — it does not ask whether Maidenhair Fern is a good idea for someone in your situation. Here is what our Maidenhair Fern record says about it on its own.

Maidenhair Fern: dosing

There is no standardized or well-established dose for maidenhair fern. Traditional use is mostly as a tea made from the dried fronds or as a syrup, but exact safe and effective amounts have not been confirmed by research.If you choose to use it, follow the directions on the product label and do not exceed the suggested amount. A pharmacist can help you decide whether it is appropriate for you and review it alongside your other medicines and supplements.

From our Maidenhair Fern monograph — the full record covers uses, side effects and every documented interaction.

Read the full Maidenhair Fern monograph & all interactions
Medication

About Testosterone Injection

What Is Testosterone Injection Used For?

Brand name: Xyosted

Testosterone injections replace testosterone when the body makes too little or none. The label describes this in men with primary hypogonadism (a problem in the testicles) and hypogonadotropic hypogonadism (a problem with the pituitary or hypothalamus signals).

Testosterone Enanthate Injection is also used to stimulate puberty in carefully selected boys with clearly delayed puberty. It may be used secondarily in some postmenopausal women with advanced, inoperable breast cancer that has spread to the bone, under an oncologist’s direction. Aveed is for hypogonadism in men and is not for use in women.

Most-Reported Side Effects for Testosterone Enanthate

From FAERS, the FDA’s public side-effect reporting system (1,589 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Injection site pain 153 reports
Injection site haemorrhage 133 reports
Injection site mass 59 reports
Fatigue 57 reports
Injection site bruising 56 reports
See full Testosterone Injection drug information
Keep checking

Other Drugs & Maidenhair Fern

Browse every other medication we’ve checked against Maidenhair Fern — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Maidenhair Fern References

The 2 references that drive our Maidenhair Fern monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Maidenhair Fern and Testosterone Enanthate Together: Common Questions

Is it safe to take Maidenhair Fern with Testosterone Enanthate?
We do not list a known interaction between Maidenhair Fern and Testosterone Enanthate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Testosterone Enanthate interact with any supplements?
Yes. Testosterone Enanthate has documented interactions with 184 supplements in our database — Maidenhair Fern is not one of them. The Testosterone Enanthate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Testosterone Enanthate and Maidenhair Fern?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.