Drug & supplement interaction

Miracle Fruit + Cisplatin

Cisplatin brand name: Platinol-AQ.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Miracle Fruit and Cisplatin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Miracle Fruit and Cisplatin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Cisplatin and Miracle Fruit in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Miracle Fruit safety at a glance

Miracle Fruit overall Use caution Generally well tolerated as a food, but long-term and high-dose safety has not been well studied.
Pregnancy Use caution There is not enough reliable safety data, so it is best to avoid concentrated supplements and use caution.
Breastfeeding Use caution There is not enough reliable safety data, so caution is advised.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Cisplatin and Miracle Fruit? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Cisplatin

Interactions in our licensed database are recorded against drug classes, not just single drug names. Cisplatin is filed under 6 classifications — including platinum agents, alkylating agents, immunosuppressants. Miracle Fruit has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Cisplatin’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Miracle Fruit Does Interact With Other Medications

Miracle Fruit has 86 moderate known drug interactions in our database — Cisplatin isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Miracle Fruit

Covers the 2,830 medications we’ve checked against Miracle Fruit. Pick one to open its full report.

What to actually watch for

What Cisplatin’s Own FDA Label Lists

This is not an interaction — none of it involves Miracle Fruit. These are the most notable effects listed in the ADVERSE REACTIONS section of Cisplatin’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • An electrolyte imbalance Worth acting on
  • Loss of vision Worth acting on
  • Low magnesium Worth acting on
  • Hearing loss Worth acting on
  • A stroke or mini-stroke Worth acting on
  • Dehydration Worth acting on
  • Low sodium Worth acting on
  • A low white blood cell count Worth acting on mentioned in 12.2% of FDA reports for Cisplatin
  • Low potassium Worth acting on
  • A heart attack Worth acting on

Showing the 10 most notable of 33 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Cisplatin. Read the label on DailyMed › Where a percentage is shown, it is the share of 77,669 voluntary FDA FAERS reports for Cisplatin that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Miracle Fruit’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Miracle Fruit side to compare — that is a limit of the record, not a statement that Miracle Fruit has no side effects.

Everything else you take

See Every Supplement That Interacts With Cisplatin

This page covers Miracle Fruit only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Cisplatin page lists 90 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Siberian Cocklebur (major), Acerola (moderate) and Active Hexose Correlated Compound (ahcc) (moderate).

By severity: 3 major · 75 moderate · 12 minor.

From our pharmacist’s overview on the Cisplatin page

“Kidney damage is the risk I would flag first for anyone receiving cisplatin (Platinol-AQ). Cisplatin is a chemotherapy drug that already stresses the kidneys, and two of the three major-rated interactions on this list, Siberian cocklebur and asarabacca, involve herbs that can injure the kidneys on their own, stacking harm on an organ t…”

Reviewed by 2 · Jul 18, 2026

Open the Cisplatin interaction page

How much people look this up

Where Miracle Fruit and Cisplatin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Miracle Fruit
Steady interest

#828 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Cisplatin
Steady interest

#1,598 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Miracle Fruit reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Miracle Fruit and Cisplatin records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Miracle Fruit

What is Miracle Fruit?

Miracle Fruit
  • Making sour foods taste sweet
  • Sugar substitute or sweetness enhancer
  • Reducing added sugar intake
  • Improving taste during chemotherapy
  • Novelty 'flavor tripping' experiences

Miracle fruit contains a protein called miraculin that temporarily makes sour and acidic foods taste sweet for up to about an hour. It is generally considered safe as a food when used occasionally, but high-quality research on any health benefits is limited. If you are pregnant, breastfeeding, or have a medical condition, check with your pharmacist or doctor first.

Synsepalum dulcificum · Sapotaceae · Fruit (berry) · Fresh berries, freeze-dried tablets, freeze-dried powder, frozen pulp

An interaction check asks whether these two react with each other — it does not ask whether Miracle Fruit is a good idea for someone in your situation. Here is what our Miracle Fruit record says about it on its own.

Miracle Fruit: dosing

There is no official or standardized medical dose for miracle fruit. Products are usually sold as a single fresh berry, a freeze-dried tablet, or a small amount of powder meant for one taste-changing session.The best approach is to follow the directions on the product label and not use more than recommended.

From our Miracle Fruit monograph — the full record covers uses, side effects and every documented interaction.

Read the full Miracle Fruit monograph & all interactions
Medication

About Cisplatin Injection

What Is Cisplatin Injection Used For?

Brand name: Platinol-AQ

Cisplatin Injection is used to treat three types of cancer. For metastatic testicular tumors and metastatic ovarian tumors, it is used as part of combination chemotherapy — alongside other approved cancer medicines — in patients who have already had surgery and/or radiation therapy. For metastatic ovarian tumors, it can also be used alone as a second-line treatment when standard chemotherapy has stopped working and cisplatin has not been tried before.

For advanced bladder cancer (specifically transitional cell bladder cancer) that can no longer be treated with surgery or radiation, Cisplatin Injection is used as a single agent.

Most-Reported Side Effects for Cisplatin

From FAERS, the FDA’s public side-effect reporting system (77,669 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Nausea 5,437 reports
Neutropenia 4,877 reports
Disease progression 4,657 reports
Febrile neutropenia 4,606 reports
Vomiting 4,566 reports
See full Cisplatin Injection drug information
Keep checking

Other Drugs & Miracle Fruit

Browse every other medication we’ve checked against Miracle Fruit — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Miracle Fruit page.

No interaction 2,743 drugs checked — show the list
Evidence & sources

Miracle Fruit References

The 1 references that drive our Miracle Fruit monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Obafemi TO, Olaleye MT, Akinmoladun AC. Antidiabetic property of miracle fruit plant (Synsepalum dulcificum Shumach. & Thonn. Daniell) leaf extracts in fructose-fed streptozotocin-injected rats via anti-inflammatory activity and inhibition of carbohydrate

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Miracle Fruit and Cisplatin Together: Common Questions

Is it safe to take Miracle Fruit with Cisplatin?
We do not list a known interaction between Miracle Fruit and Cisplatin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Miracle Fruit and Cisplatin combination checked?
Interactions in our licensed database are recorded against drug classes. Cisplatin is filed under 6 classifications, and Miracle Fruit has documented interactions with 1 drug class — none of Cisplatin's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Miracle Fruit interact with any other medications?
Yes. Miracle Fruit has 86 documented drug interactions in our database — Cisplatin is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Cisplatin interact with any supplements?
Yes. Cisplatin has documented interactions with 90 supplements in our database — Miracle Fruit is not one of them. The Cisplatin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Cisplatin and Miracle Fruit?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.