Drug & supplement interaction

Monterey Pine + Brexpiprazole

Brexpiprazole brand name: Rexulti.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Monterey Pine and Brexpiprazole in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Monterey Pine and Brexpiprazole

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Brexpiprazole and Monterey Pine in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Monterey Pine at all — not against Brexpiprazole, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Monterey Pine safety at a glance

Monterey Pine overall Not established There is little human safety data for Monterey Pine taken as a supplement.
Pregnancy Avoid Safety is not established, so it is best to avoid during pregnancy.
Breastfeeding Avoid Safety is not established, so it is best to avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Brexpiprazole and Monterey Pine? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Monterey Pine Itself Has Been Linked To

This is not an interaction — nothing below involves Brexpiprazole. It is the side-effect record for Monterey Pine on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Monterey Pine, this list is the first place to look.

  • A skin rash Additional detail

    “Contact dermatitis from Monterey pine sawdust has been reported.”

    Monterey Pine · Natural Medicines adverse-effect record, reported in dermatitis.

    1 source cited
    1. 63615. Burry, J. N. Environmental dermatitis: contact dermatitis from Pinus radiata. Med J Aust. 7-2-1977;2(1):13-14. DOI

Everything above comes from the Natural Medicines adverse-effect record for Monterey Pine — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Brexpiprazole’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Brexpiprazole column appears here.

Everything else you take

See Every Supplement That Interacts With Brexpiprazole

This page covers Monterey Pine only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Brexpiprazole page lists 177 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), Indian Snakeroot (major), Lithium (major) and Rauvolfia Vomitoria (major).

By severity: 6 major · 130 moderate · 41 minor.

From our pharmacist’s overview on the Brexpiprazole page

“Brexpiprazole (Rexulti) treats schizophrenia and is added to antidepressants for depression, and its supplement list warrants real care before you add anything to it. The bulk of the 177 entries change how your liver clears the drug, so grapefruit can push levels up while St.”

Reviewed by 2 · Jul 18, 2026

Open the Brexpiprazole interaction page

One more smart check

Taking Monterey Pine as Part of a Dietary Supplement Product? Check It for Interactions

We hold 43 real supplement products containing Monterey Pine, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Monterey Pine. Even though Monterey Pine itself has no known interaction with Brexpiprazole, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Monterey Pine and Brexpiprazole Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Monterey Pine
Top half

#682 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Brexpiprazole
Steady interest

#1,435 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Monterey Pine reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Monterey Pine and Brexpiprazole records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Monterey Pine

What is Monterey Pine?

Monterey Pine
  • Antioxidant support
  • Skin and aging concerns
  • Circulation support
  • Inflammation
  • Respiratory comfort

Monterey Pine is mainly a timber tree, and human evidence for its use as a supplement is very limited. Some pine bark extracts are studied for antioxidant effects, but most claims specific to Monterey Pine are not well proven. Talk to a pharmacist or doctor before using any pine-based product.

Pinus radiata · Pinaceae · Bark, needles, and essential oil · Bark extract supplements, essential oil, needle tea

An interaction check asks whether these two react with each other — it does not ask whether Monterey Pine is a good idea for someone in your situation. Here is what our Monterey Pine record says about it on its own.

Monterey Pine: dosing

There is no established standard dose for Monterey Pine. Because products vary widely in strength and form, a safe, proven amount has not been set.If you choose to use a pine-derived product, follow the directions on the label and do not exceed them. Essential oils are for external or aromatherapy use only unless a professional advises otherwise.

From our Monterey Pine monograph — the full record covers uses, side effects and every documented interaction.

Read the full Monterey Pine monograph & all interactions
Medication

About Brexpiprazole

What Is Brexpiprazole Used For?

Brand name: Rexulti

Brexpiprazole tablets are approved for two uses in adults: as an add-on (adjunctive) treatment alongside antidepressants for major depressive disorder (MDD), and as a treatment for schizophrenia. These uses apply to both the generic brexpiprazole tablets and Rexulti.

Rexulti has one additional approved use: treating agitation associated with dementia due to Alzheimer's disease in adults. Rexulti is also approved for schizophrenia in adolescents ages 13 and older. Note that Rexulti is not approved for dementia-related psychosis without agitation from Alzheimer's disease, and it is not meant to be used on an as-needed basis for Alzheimer's-related agitation.

Most-Reported Side Effects for Brexpiprazole

From FAERS, the FDA’s public side-effect reporting system (16,505 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Weight increased 1,702 reports
Akathisia 869 reports
Tremor 654 reports
Anxiety 612 reports
Tardive dyskinesia 599 reports
See full Brexpiprazole drug information
Keep checking

Other Drugs & Monterey Pine

Browse every other medication we’ve checked against Monterey Pine — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Monterey Pine References

The 1 references that drive our Monterey Pine monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Burry, J. N. Environmental dermatitis: contact dermatitis from Pinus radiata. Med J Aust. 7-2-1977;2(1):13-14. DOI

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Monterey Pine and Brexpiprazole Together: Common Questions

Is it safe to take Monterey Pine with Brexpiprazole?
We do not list a known interaction between Monterey Pine and Brexpiprazole. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Brexpiprazole interact with any supplements?
Yes. Brexpiprazole has documented interactions with 177 supplements in our database — Monterey Pine is not one of them. The Brexpiprazole interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Brexpiprazole and Monterey Pine?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.