Drug & supplement interaction

Mountain Ash + Melphalan Flufenamide

Melphalan Flufenamide brand name: Pepaxto.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Mountain Ash and Melphalan Flufenamide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Mountain Ash and Melphalan Flufenamide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Melphalan Flufenamide and Mountain Ash in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Mountain Ash safety at a glance

Mountain Ash overall Use caution Cooked berries are generally well tolerated in food amounts, but raw berries can cause stomach upset and evidence for medicinal use is limited.
Pregnancy Possibly Unsafe When large amounts of fresh berries are ingested. There is insufficient reliable information available about the safety of dried or cooked berries; avoid using. Read the full pregnancy detail
Breastfeeding Possibly Unsafe When large amounts of fresh berries are ingested. There is insufficient reliable information available about the safety of dried or cooked berries; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Melphalan Flufenamide and Mountain Ash? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Melphalan Flufenamide

Interactions in our licensed database are recorded against drug classes, not just single drug names. Melphalan Flufenamide is filed under a single classification — alkylating agents. Mountain Ash has documented interactions with 1 drug class — the most serious being nephrotoxic drugs (moderate) — and none of Melphalan Flufenamide’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Mountain Ash Does Interact With Other Medications

Mountain Ash has 355 moderate known drug interactions in our database — Melphalan Flufenamide isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Mountain Ash

Covers the 2,830 medications we’ve checked against Mountain Ash. Pick one to open its full report.

What to actually watch for

What Mountain Ash Itself Has Been Linked To

This is not an interaction — nothing below involves Melphalan Flufenamide. It is the side-effect record for Mountain Ash on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Mountain Ash, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Kidney problems Worth acting on Additional detail

    “Orally, consuming large amounts of fresh mountain ash berries can cause serious adverse effects due to its parasorbic acid constituent. These adverse effects include gastroenteritis, vomiting, queasiness, gastric pain, diarrhea, kidney damage, and polymorphic xanthomas (18).”

    Mountain Ash · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    “Orally, large amounts of fresh mountain ash berries may cause kidney damage, including albuminuria and glycosuria, due to its parasorbic acid constituent (18).”

    Mountain Ash · Natural Medicines adverse-effect record, reported in albuminuria.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  • Diarrhea / Vomiting / Nausea Additional detail

    “Orally, large amounts of fresh mountain ash berries may cause gastroenteritis, vomiting, queasiness, gastric pain, and diarrhea due to its parasorbic acid constituent (18).”

    Mountain Ash · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Everything above comes from the Natural Medicines adverse-effect record for Mountain Ash — expand a row for the licensed statement it rests on. We haven’t matched Melphalan Flufenamide to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Melphalan Flufenamide.

Special populations

Mountain Ash in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When large amounts of fresh berries are ingested. There is insufficient reliable information available about the safety of dried or cooked berries; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Melphalan Flufenamide

This page covers Mountain Ash only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Melphalan Flufenamide page lists 7 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Acerola (moderate), Alpha-lipoic Acid (moderate), Coenzyme Q10 (moderate), Rose Hip (moderate) and Turmeric (moderate).

By severity: 7 moderate.

From our pharmacist’s overview on the Melphalan Flufenamide page

“The single most important thing on this page is antioxidants. Melphalan flufenamide (Pepaxto) is a chemotherapy used for multiple myeloma, and part of how it kills cancer cells is by generating free radicals.”

Reviewed by 2 · Jul 18, 2026

Open the Melphalan Flufenamide interaction page

One more smart check

Taking Mountain Ash as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing Mountain Ash, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Mountain Ash. Even though Mountain Ash itself has no known interaction with Melphalan Flufenamide, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Mountain Ash and Melphalan Flufenamide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Mountain Ash
Top half

#690 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Melphalan Flufenamide
Top half

#1,171 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Mountain Ash reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Mountain Ash and Melphalan Flufenamide records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Mountain Ash

What is Mountain Ash?

Mountain Ash
  • Sore throat and hoarseness
  • Digestive upset and constipation
  • Cough and chest congestion
  • Mild urinary complaints
  • Source of vitamin C in folk medicine

Mountain ash (rowan) is a northern-hemisphere tree whose bright red berries are traditionally cooked into jams, syrups, and teas. There is very little reliable human research to support any medical use, and raw berries contain compounds that can cause stomach upset, so cooking is important. If you want to try it, talk with your pharmacist or doctor first.

Sorbus aucuparia · Rosaceae · Fruit (berries), and sometimes the flowers and bark · Cooked berries, jam or jelly, juice, syrup, tea, tincture

An interaction check asks whether these two react with each other — it does not ask whether Mountain Ash is a good idea for someone in your situation. Here is what our Mountain Ash record says about it on its own.

Mountain Ash: dosing

There is no established or standardized medicinal dose for mountain ash. It is most often consumed as cooked berries, jam, syrup, or tea rather than as a measured supplement.If you use a commercial product, follow the directions on the label and do not exceed the suggested amount.

From our Mountain Ash monograph — the full record covers uses, side effects and every documented interaction.

Read the full Mountain Ash monograph & all interactions
Medication

About Melphalan Flufenamide Injection

What Is Melphalan Flufenamide Injection Used For?

Brand name: Pepaxto

  • Melphalan flufenamide injection is used along with dexamethasone to treat multiple myeloma (a type of cancer of the bone marrow) in adults whose disease has returned or has not improved after receiving at least four other chemotherapy medications. Melphalan flufenamide is in a class of medications called alkylating agents. It works by stopping or slowing the growth of cancer cells in your body.

See full Melphalan Flufenamide Injection drug information
Keep checking

Other Drugs & Mountain Ash

Browse every other medication we’ve checked against Mountain Ash — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
355Moderate
0Minor
2,474No known interaction
Moderate

355 interactions

Showing 60 of 355 moderate interactions — see all 355 on the Mountain Ash page.

No interaction 2,474 drugs checked — show the list
Evidence & sources

Mountain Ash References

The 1 references that drive our Mountain Ash monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Mountain Ash and Melphalan Flufenamide Together: Common Questions

Is it safe to take Mountain Ash with Melphalan Flufenamide?
We do not list a known interaction between Mountain Ash and Melphalan Flufenamide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Mountain Ash and Melphalan Flufenamide combination checked?
Interactions in our licensed database are recorded against drug classes. Melphalan Flufenamide is filed under 1 classification, and Mountain Ash has documented interactions with 1 drug class — none of Melphalan Flufenamide's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Mountain Ash interact with any other medications?
Yes. Mountain Ash has 355 documented drug interactions in our database — Melphalan Flufenamide is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Melphalan Flufenamide interact with any supplements?
Yes. Melphalan Flufenamide has documented interactions with 7 supplements in our database — Mountain Ash is not one of them. The Melphalan Flufenamide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Melphalan Flufenamide and Mountain Ash?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.