Drug & supplement interaction

Nasturtium + Brexpiprazole

Brexpiprazole brand name: Rexulti.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Nasturtium and Brexpiprazole in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

Know someone taking this? Share
Interaction report

Nasturtium and Brexpiprazole

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Brexpiprazole and Nasturtium in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Nasturtium at all — not against Brexpiprazole, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Nasturtium safety at a glance

Nasturtium overall Use caution Generally considered safe as a food, but concentrated extracts have limited safety data.
Pregnancy Avoid Not enough safety information; medicinal amounts are best avoided during pregnancy.
Breastfeeding Use caution Safety during breastfeeding is not well studied, so caution is advised.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Brexpiprazole and Nasturtium? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Nasturtium Itself Has Been Linked To

This is not an interaction — nothing below involves Brexpiprazole. It is the side-effect record for Nasturtium on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Nasturtium, this list is the first place to look.

  • A skin rash Additional detail

    “Orally, large amounts of nasturtium or benzyl mustard oil, a constituent of nasturtium, can cause gastrointestinal tract irritation (2,18). Large amounts of nasturtium can cause albuminuria due to glomerular and tubular damage (2).

    Topically, contact with the nasturtium plant and its benzyl mustard oil constituent can cause skin and mucosal irritation (2,18).”

    Nasturtium · Natural Medicines adverse-effect record, reported in albuminuria.

    3 sources cited
    1. 2. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
    2. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
    3. 99386. Perez-Crespo M, Silvestre JF, Mataix J, Ballester I, Toledo F, Betlloch I. Contact dermatitis due to nasturtium. Contact Dermatitis. 2009;60(4):229-30. PubMed

    “Topically, contact with the nasturtium plant and its benzyl mustard oil constituent can cause skin and mucosal irritation (2,18). Benzyl mustard oil is a contact allergen if applied to the skin. There are multiple case reports of contact dermatitis attributed to nasturtium.”

    Nasturtium · Natural Medicines adverse-effect record, reported in dermatitis.

    3 sources cited
    1. 2. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
    2. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
    3. 99386. Perez-Crespo M, Silvestre JF, Mataix J, Ballester I, Toledo F, Betlloch I. Contact dermatitis due to nasturtium. Contact Dermatitis. 2009;60(4):229-30. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Nasturtium — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Brexpiprazole’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Brexpiprazole column appears here.

Everything else you take

See Every Supplement That Interacts With Brexpiprazole

This page covers Nasturtium only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Brexpiprazole page lists 177 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), Indian Snakeroot (major), Lithium (major) and Rauvolfia Vomitoria (major).

By severity: 6 major · 130 moderate · 41 minor.

From our pharmacist’s overview on the Brexpiprazole page

“Brexpiprazole (Rexulti) treats schizophrenia and is added to antidepressants for depression, and its supplement list warrants real care before you add anything to it. The bulk of the 177 entries change how your liver clears the drug, so grapefruit can push levels up while St.”

Reviewed by 2 · Jul 18, 2026

Open the Brexpiprazole interaction page

One more smart check

Taking Nasturtium as Part of a Dietary Supplement Product? Check It for Interactions

We hold 3 real supplement products containing Nasturtium, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Nasturtium. Even though Nasturtium itself has no known interaction with Brexpiprazole, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Nasturtium and Brexpiprazole Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Nasturtium
Top half

#402 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Brexpiprazole
Top half

#983 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Nasturtium reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Nasturtium and Brexpiprazole records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Nasturtium

What is Nasturtium?

  • Urinary tract infections
  • Respiratory infections and congestion
  • Antimicrobial support
  • Wound and skin care (topical)
  • Mild cold and cough symptoms

Nasturtium is an edible garden plant traditionally used for urinary and respiratory infections, often combined with horseradish in herbal products. Some lab studies suggest it has antimicrobial activity, but high-quality human evidence is limited. Talk with your pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have kidney or stomach problems.

Tropaeolum majus · Tropaeolaceae · Leaves, flowers, and seeds · Fresh leaves and flowers (food/salad), dried herb, tea, capsules, tinctures, and combination herbal products

An interaction check asks whether these two react with each other — it does not ask whether Nasturtium is a good idea for someone in your situation. Here is what our Nasturtium record says about it on its own.

Nasturtium: dosing

There is no well-established standardized dose for nasturtium. Amounts vary widely depending on whether you use fresh leaves, dried herb, tea, capsules, or a combination product.The best approach is to follow the directions on the product label and not exceed the recommended amount.

From our Nasturtium monograph — the full record covers uses, side effects and every documented interaction.

Read the full Nasturtium monograph & all interactions
Medication

About Brexpiprazole

What Is Brexpiprazole Used For?

Brand name: Rexulti

Brexpiprazole tablets are approved for two uses in adults: as an add-on (adjunctive) treatment alongside antidepressants for major depressive disorder (MDD), and as a treatment for schizophrenia. These uses apply to both the generic brexpiprazole tablets and Rexulti.

Rexulti has one additional approved use: treating agitation associated with dementia due to Alzheimer's disease in adults. Rexulti is also approved for schizophrenia in adolescents ages 13 and older. Note that Rexulti is not approved for dementia-related psychosis without agitation from Alzheimer's disease, and it is not meant to be used on an as-needed basis for Alzheimer's-related agitation.

Most-Reported Side Effects for Brexpiprazole

From FAERS, the FDA’s public side-effect reporting system (16,505 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Weight increased 1,702 reports
Akathisia 869 reports
Tremor 654 reports
Anxiety 612 reports
Tardive dyskinesia 599 reports
See full Brexpiprazole drug information
Keep checking

Other Drugs & Nasturtium

Browse every other medication we’ve checked against Nasturtium — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Nasturtium References

The 5 references that drive our Nasturtium monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Fintelmann V, Albrecht U, Schmitz G, Schnitker J. Efficacy and safety of a combination herbal medicinal product containing Tropaeoli majoris herba and Armoraciae rusticanae radix for the prophylactic treatment of patients with respiratory tract diseases:
  4. Albrecht U, Goos KH, Schneider B. A randomised, double-blind, placebo-controlled trial of a herbal medicinal product containing Tropaeoli majoris herba (Nasturtium) and Armoraciae rusticanae radix (Horseradish) for the prophylactic treatment of patients w
  5. Perez-Crespo M, Silvestre JF, Mataix J, Ballester I, Toledo F, Betlloch I. Contact dermatitis due to nasturtium. Contact Dermatitis. 2009;60(4):229-30. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Nasturtium and Brexpiprazole Together: Common Questions

Is it safe to take Nasturtium with Brexpiprazole?
We do not list a known interaction between Nasturtium and Brexpiprazole. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Brexpiprazole interact with any supplements?
Yes. Brexpiprazole has documented interactions with 177 supplements in our database — Nasturtium is not one of them. The Brexpiprazole interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Brexpiprazole and Nasturtium?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.